key: cord-0695933-c416r3w9
authors: Jiang, Fenglin
title: Letter to the Editor regarding article “Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID‐19 pneumonia”
date: 2021-07-21
journal: Ann Noninvasive Electrocardiol
DOI: 10.1111/anec.12868
sha: 7a6c4e433362bbf109f1cb258a41addf04b95c12
doc_id: 695933
cord_uid: c416r3w9

nan

Dear Editor,

We have read with great interest the article "Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia" by Alareedh et al., (2021) .

The difference between respiratory system virus, circulatory system virus, pulmonary hemorrhagic fever virus, and enterovirus is not very important. Is there still less virus in E. coli culture?

ACE2 mediates the destruction of endothelial cells, and thrombosis may be the mechanism. Where is prethrombotic state and hypercoagulable state? It is just an academic discussion of assumptions. The ECG of pulmonary embolism is the camouflager of the heart world.

It has various manifestations. Autopsy seems to have proved everything and myocardial infarction.

higher in the intensive care unit /severely ill than in less critical patients. The cytokine release with complement and iNO dysregulation are established mechanisms potentially leading to sepsisrelated cardiomyopathy, making sepsis per se one of the potential mechanism leading to acute cardiac injury in COVID-19 patients.

Moreover, the hyper-inflammation with endothelial dysfunction is likely be responsible of both pulmonary in situ platelet aggregation and deep thrombosis potentially leading to severe pulmonary embolism and right ventricular failure (Tavazzi et al., 2020) . et al., 2021) . The COVID-19, due to SARS-CoV-2, has uncovered many real-world issues when it comes to healthcare management and has led to widespread mortality. These include myopericarditis, acute coronary syndromes, thrombosis, arrhythmias, hypertension, and heart failure (Veldtman et al., 2020) . Novel coronavirus disease (COVID-19) has led to a major public health crisis globally.

Currently, myocardial damage is speculated to be associated with COVID-19, which can be seen as one of the main causes of death of patients with COVID-19 (Liaqat et al., 2021) . These cases sug- 

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Electrocardiographic markers of increased risk of sudden cardiac death in patients with COVID-19 pneumonia