key: cord-0692575-nl2ct49j
authors: Khoiwal, Kavita; Kalita, Deepjyoti; Shankar, Ravi; Kumari, Reena; Dhundi, Deepika; Bahadur, Anupama; Panda, Prasan Kumar; Chaturvedi, Jaya
title: Identification of SARS‐CoV‐2 in the vaginal fluid and cervical exfoliated cells of women with active COVID‐19 infection: A pilot study
date: 2021-03-29
journal: Int J Gynaecol Obstet
DOI: 10.1002/ijgo.13671
sha: 5dd71c1c467f56ea0a975fc81303cf935a398a14
doc_id: 692575
cord_uid: nl2ct49j

In women with confirmed COVID‐19, a negative RT‐PCR test result does not rule out the possibility of a low level of SARS‐CoV‐2 in the female genital tract.

Out of these three participants, two were premenopausal and one was postmenopausal; one was symptomatic with COVID-19-related pneumonia (moderate), and the other two had asymptomatic COVID-19

infection and were admitted for gynecological indications.

We could only find one study which reported detection of SARS-CoV-2 in vaginal swabs, 3 while other case studies did not identify the presence of SARS-CoV-2 in vaginal fluid. 4, 5 The detection rate in the present study was 20%, which might be explained by the higher analytical sensitivity and specificity of TMA-based technology than RT-PCR testing. 6, 7 The strengths of the study were its prospective nature, inclu- infection.

The authors have no conflicts of interest. 

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