key: cord-0692387-mx8wgkja
authors: Annunziata, Maria Carmela; Patrì, Angela; Ruggiero, Angelo; Di Guida, Adriana; Menicanti, Claudia; Greco, Vincenzo; Fabbrocini, Gabriella
title: Cutaneous involvement during COVID‐19 pandemic: an emerging sign of infection
date: 2020-06-18
journal: J Eur Acad Dermatol Venereol
DOI: 10.1111/jdv.16769
sha: c186861ee172ffb26d6e247c7484a7017f584690
doc_id: 692387
cord_uid: mx8wgkja

Since December 2019, SARS‐CoV‐2 epidemic has spread all over the world.(1) To date, few reports regarding the cutaneous involvement in COVID‐19 have been published.(2,3) Herein, we report a four cases series describing skin lesions probably related with COVID‐19. The case 1 was a 66‐year‐old Caucasian female with a history of hypertension and dyslipidaemia. When hospitalized, she showed fever, nasal congestion and pneumonia symptoms. A chest‐TC displayed bilateral interstitial lungs’ involvement and a nasopharyngeal‐swab confirmed SARS‐CoV‐2 infection. At day 6 of hospitalization, an asymptomatic erythematous‐pomphoid skin rash occurred on the trunk (Figure 1A).

regarding the cutaneous involvement in COVID-19 have been published. 2, 3 Herein, we report a four cases series describing skin lesions probably related with COVID-19. The case 1 was a 66-year-old Caucasian female with a history of hypertension and dyslipidaemia. When hospitalized, she showed fever, nasal congestion and pneumonia symptoms. A chest-TC displayed bilateral interstitial lungs' involvement and a nasopharyngeal-swab confirmed SARS-CoV-2 infection. At day 6 of hospitalization, an asymptomatic erythematous-pomphoid skin rash occurred on the trunk ( Figure   1A ). The case 2 was a 60-year-old Caucasian female tested positive for SARS-CoV-2. A chest-TC confirmed lungs' involvement. Patient's comorbidities were diabetes and hypertension. When hospitalized, systemic symptoms included headache, fever, nasal congestion and cough. At day 9 of hospitalization, the patient referred abdomen pruritus. After 24 hours, an erythematous rash with vesicles and crusts developed on the abdomen ( Figure 1B ). The case 3 was a 30-year-old Caucasian male in home quarantine due to a contact with a COVID-19 confirmed case, which consulted our dermatological clinic through tele-dermatology services 4 for the onset of a cutaneous rash. After 2 days of fever, pruritic erythematous papules and vesicles had developed on the trunk. The lesions resolved spontaneously in 10 days ( Figure 2A ). The case 4 was a 30-year-old Caucasian male, in home isolation, which showed fever and cough as first symptoms. After 3 days, a tele-

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