key: cord-0688421-0yk04zx8
authors: Díaz, Cristóbal; Contreras, Julio J.; Muñoz, Martín; Osorio, Matías; Quiroz, Milton; Pizarro, Renato
title: Parsonage-Turner syndrome association with SARS-CoV-2 infection.
date: 2021-04-21
journal: JSES reviews, reports, and techniques
DOI: 10.1016/j.xrrt.2021.04.002
sha: 2c3dcd9808e74c19774675ac71933384f16b1b93
doc_id: 688421
cord_uid: 0yk04zx8

Parsonage-Turner syndrome (PTS), also known as idiopathic brachial plexopathy or neuralgic amyotrophy, was first described by Julius Dreschfeld in 1887. PTS is characterized by a single or multiple mononeuropathies at the level of the brachial plexus (not exclusive), acute and self-limited, associated with motor deficit and muscle atrophy. The exact pathophysiology is still unknown. Of the many proposed causes, an infectious or immune-mediated process seems to be the most supported. Viral illness is the most common associated risk factor (25% to 55%). Currently, there are only three case reports in the literature on the relation of COVID-19 with PTS. The COVID- 19 neurological involvement has been described mainly at the central nervous system, with Guillain-Barré syndrome being the most frequent at the peripheral nervous system. In the context of a coronavirus pandemic, we should suspect this disease in patients with neuropathic pain in the shoulder region within the possible differential diagnoses. This publication is about a case of PTS in association with COVID-19 and a review of scientific literature available.

Currently, there are only three case reports in the literature on the relation of COVID-19 26 with PTS 1, 8, 14 . The COVID-19 neurological involvement has been described mainly at the 27 central nervous system, with Guillain-Barré syndrome being the most frequent at the 28 peripheral nervous system 2 . In the context of a coronavirus pandemic, we should suspect 29 this disease in patients with neuropathic pain in the shoulder region within the possible 30 differential diagnoses. This publication is about a case of PTS in association with COVID-31 19 and a review of scientific literature available. (Table 1) . Electrodiagnostic evaluation (nerve conduction study and needle electromyography, Table   63 2) showed signs suggestive of a subacute and severe degree of right brachial plexopathy J o u r n a l P r e -p r o o f

Pure sensory neuralgic amyotrophy in 166

167 2. Carod-Artal FJ. Neurological complications of coronavirus and COVID-19

Immune 203 brachial plexus neuropathy: Suggestive evidence for an inflammatory-immune 204 pathogenesis

Neuralgic amyotrophy 206 (Parsonage-Turner syndrome)

Natural history of brachial plexus neuropathy