key: cord-0681865-mttay3hy
authors: Mastrangelo, Andrea; Germinario, Bruno Nicolò; Ferrante, Marica; Frangi, Claudia; Li Voti, Raffaele; Muccini, Camilla; Ripa, Marco
title: Candidemia in COVID-19 patients: incidence and characteristics in a prospective cohort compared to historical non-COVID-19 controls
date: 2020-10-30
journal: Clin Infect Dis
DOI: 10.1093/cid/ciaa1594
sha: 336fd5854d7782ce6ba877f8a9165b992a46dd1c
doc_id: 681865
cord_uid: mttay3hy

nan

M a n u s c r i p t 2 Dear Editor,

We have read with interest the article by Lewis White and Colleagues, providing insights on invasive fungal infections in COVID-19 patients [1] . The Authors describe a significant proportion of invasive yeast infections, especially candidemia. It is not clear to date if the incidence of candidemia in COVID-19 patients is higher than expected. Moreover, no comparison of clinical presentation and outcomes between affected patients with and without COVID-19 is available.

To investigate these points, we compared the incidence and characteristics of candidemia in a prospective cohort of patients with SARS-CoV-2 infection to those of a historical cohort of non- Limitations of this work include the monocentric retrospective design, and the limited sample size.

In conclusion, we observed an increased incidence of candidemia in hospitalized patients with COVID-19 compared to a historical non-COVID-19 cohort. We found no imbalance in several 

We would like to thank all the physicians, nurses and healthcare workers of San Raffaele Hospital, whose efforts have contributed to mitigate the impact of COVID-19 pandemic.

There was no funding source for this study.

A c c e p t e d M a n u s c r i p t A c c e p t e d M a n u s c r i p t 6 

A national strategy to diagnose COVID-19 associated