key: cord-0252604-b67xpq12 authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj title: Frequency of diarrhea in novel coronavirus 2019 infection date: 2020 journal: Gastroenterol Hepatol Bed Bench DOI: nan sha: be5027b049d344e83ba4fbd6150bbab3f8623004 doc_id: 252604 cord_uid: b67xpq12 nan . This disease started in China then it is imported to several countries. As a new disease, knowledge on its clinical feature is limited. In additional to respiratory manifestation, atypical clinical presentation of the new disease is possible. An important atypical clinical presentation is diarrhea. Here, the authors performed a summative analysis on available data on 314 cases of novel coronavirus 2019 infections (2 -4) to calculate for frequency of diarrhea. Of those 140 cases, diarrhea is presented in 3 cases. The frequency of diarrhea is 2.14 % (95 % confidence interval = 0.70 % -6.56 %). Based on this observation, it can show that diarrhea is a possible atypical clinical presentation of novel coronavirus 2019 infection. in fact, diarrhea is usually a possible but forgotten clinical presentation in new emerging disease such as swine flu (5) . Practitioner should recognize the possibility that diarrhea might be the first clinical presentation of the patient with novel coronavirus 2019 infection. Nevertheless, the exact pathophysiology of diarrhea in novel coronavirus 2019 infection is unknown. Further study on this issue is recommende. Emerging new coronavirus infection in Wuhan, China: situation in early 2020 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia Wiwanitkit V Diarrhoea as a presentation of bird flu infection: a summary on its correlation to outcome in Thai cases