key: cord-0130881-30692i5q authors: Mahmoudi, Mohammadreza title: COVID Lessons: Was there any way to reduce the negative effect of COVID-19 on the United States economy? date: 2022-01-02 journal: nan DOI: nan sha: 7d19303e4ff3a42bc190ecebfbb4908f7b1daf0e doc_id: 130881 cord_uid: 30692i5q This paper aims to study the economic impact of COVID-19. To do that, in the first step, I showed that the adjusted SEQIER model, which is a generalization form of SEIR model, is a good fit to the real COVID-induced daily death data in a way that it could capture the nonlinearities of the data very well. Then, I used this model with extra parameters to evaluate the economic effect of COVID-19 through job market. The results show that there was a simple strategy that US government could implemented in order to reduce the negative effect of COVID-19. Because of that the answer to the paper's title is yes. If lockdown policies consider the heterogenous characteristics of population and impose more restrictions on old people and control the interactions between them and the rest of population the devastating impact of COVID-19 on people lives and US economy reduced dramatically. Specifically, based on this paper's results, this strategy could reduce the death rate and GDP loss of the United States 0.03 percent and 2 percent respectively. By comparing these results with actual data which show death rate and GDP loss 0.1 percent and 3.5 percent respectively, we could figure out that death rate reduction is 0.07 percent which means for the same percent of GDP loss executing optimal targeted policy could save 2/3 lives. Approximately, 378,000 persons dead because of COVID-19 during 2020, hence reducing death rate to 0.03 percent means saving around 280,000 lives, which is huge. as the one of the main challenges of human being in new era changed our lives dramatically, in the way that many scientists believe that our era could divided into pre-COVID and post-COVID periods. COVID-19 appeared first time in Wuhan, China but with astonishing speed spread all over the world. The reason behind creation of COVID-19 is mysterious yet, however, it takes many lives and makes huge damage in economy of countries. From late November 2019, which China announced the first case of COVID-19 in Wuhan up until December 2021 278 million positive COVID-19 cases and 5.39 million COVID-induced death have recorded worldwide. In addition, the IMF report [1] shows in advanced economies over 2020-22 the cumulative per capita income losses are expected to be 11 percent of 2019 per capita GDP. Whilst, in emerging and developing countries (excluding China) losses are equivalent to 20 percent of 2019 per capita GDP. Although, public vaccination was available at the beginning of 2021, too many undeveloped countries are falling behind, and economic inequality is worsening. In the United States as the first country with most COVID-19 cases and death toll, 51. indicate shelter-in-place policies. Source: Brzezinski et al. (2020) By analyzing the lockdown policies, we can figure out they treat all people equally and they ignore the heterogeneous characteristics of population. However, COVID-19 have affected age group differently. Based on CDC studies, risk of infection, hospitalization, and death of COVID-19 are different for various age group. This fact is shown in Table 2 . The reference age group is the 18-29 year-old category, because this group has the largest cumulative number of COVID-19 positive cases compared to other age groups. For example, compared to the 18-29 year-old individuals, hospitalization and death for people older than 85 years are 15 and 570 times higher, respectively. [4] Real data also confirmed the contents of Table 2 are old (more than 65 years old). [6] Moreover, by analyzing the data of deaths by age group we find that the 65 years and older group accounted for the highest death rate. As it is described in Figure 3 , only 2.2 percent of COVID-induced death was from young adults (18-39 years old), around 20 percent of COVID-induced death was from middle-aged adults (40-64 years old), and around 80 percent of COVID-induced death was from adults 65 years and older. 2 percent of COVID-induced death was from young adults (18-39 years old), around 20 percent of COVID-induced death was from middle-aged adults (40-64 years old), and around 80 percent of COVID-induced death was from adults 65 years and older. [6] These statistics motivate me to study COVID-19 modeling in the case of heterogenous population. By putting the age statistics of COVID-19 pandemic together we could conclude that 1) we have heterogenous population, and 2) the risk of getting infected and dying are different for each age group. Therefore, every optimal policy should consider the heterogeneity aspect of COVID-19. For example, one of the first conclusions that we could get from above data analysis was that: Since the majority of positive cases belong to 18-29 year old and the majority of death belongs to those who are 65 years and older, the optimal policy should reduce the interaction within and between these groups. In this paper, I use an adjusted SEQIHR model to study the economic effect of COVID-19 for United States. First, I introduce some important papers, which focus on compartmental models to examine COVID-19 and its economic impacts. Then, I use data and run the SEQIHR model to find the best fitted model to COVID-induced daily death data of United States as well as analyze the economic effect of COVID-19 by using multi-risk SEQIHR model to address the heterogenous feature of COVID-19 and evaluate COVIDcontrolling policies. Finally, I discuss main results and provide conclusion. Ross introduced a simple compartmental model in order to analyze the transmission of malaria between mosquitoes and humans. He also mentioned the concept of basic reproduction number for the first time in his work (Brauer, Castillo-Chavez, and Feng (2019) ). Moreover, Kermack and McKendrick (1927) , Kermack and McKendrick (1932) , and Kermack and McKendrick (1933) studied the transmission of infection using the basic compartmental models profoundly. Later, their models reformulated and used by Diekmann, Heesterbeek, and Metz (1995) Compartmental models as the mathematical modeling of infectious diseases divided population into several compartments. Based on defined compartments, we have different compartmental models such as SIR, SIS, SIRD, SEIR, and so on (Brauer, Castillo-Chavez, and Feng (2019) ). For example, in SIR model, which is known as the simplest compartmental model, the population divided into three categories: susceptible, infected, and recovered. Another famous compartmental model is SEIR model which have extra compartments named exposed group. There are many papers which employed a compartmental model to explore an outbreak (e.g. Blackwood and Childs (2018) ; GILL ; Gibson and Renshaw (1998) They argued that the compartmental models generated distinct outcomes but when fitted to the data, these results were robust to the model structure. Also, indicating the purpose of the models is very vital in the case of using complex compartmental models. In this paper, I used an adjusted SEQIHR model to analyze COVID-19 pandemic. For the first time Gumel et al. (2004) introduced SEQIHR model to study the SARS epidemic of 2002-2003. They divided population into six categories of susceptible, exposed, infected, quarantined, isolated/hospitalized, and recovered/dead to examine the effect of isolation and quarantine to control SARS outbreaks in Toronto, Beijing, Singapore, and Hong Kong. Their results indicated that the main strategy to control SARS is reducing the contact rate between susceptible and infectious groups by isolating infected individuals. Also, governments by mixing optimal isolation policies and highly effective testing programs could eradicate SARS. In addition, Siriprapaiwan, Moore, and Koonprasert (2018) did the similar approach work with updated data set and got the same results. There are many papers which utilized the compartmental model to analyze COVID-19 pandemic. In the following I summarized the results of some of the main papers. Bertozzi et al. (2020) argued that due to high fluctuation of reproduction number over time and by location, inaccuracy of COVID-19 death and positive cases data, and the difficulties of evaluating nonpharmaceutical interventions, modeling and forecasting the COVID-19 outbreaks is very challenging process. In addition, Roda et al. (2020) States correctly. Also, they claimed that it is no clear whether earlier lockdown policies would have decreased the long-term cumulative COVID-induced death. Furthermore, Sargent and Stachurski (2015) in their comprehensive book "Quantitative Economics with Julia", specifically section V: Modeling in Continuous Time, provided the Julia code for deterministic and stochastic COVID-19 modeling. There are some papers which focus on the limitations of COVID-19 modeling. For instance, Fernández-Villaverde and Jones (2020) (2021)). In addition, there are many economists who study the economic impact of COVID-19, among them I address several main papers in the following. One of the economists who study COVID-19 modeling and its effect on economy profoundly is Atkeson (2021a) . He used a model of private and public behavior to study the dynamic of COVID-19 and answer to the question how we could mitigate the effect of COVID-19 pandemic on public health. He concluded that the combination of quick non-pharmaceutical interventions and fast development of pharmaceutical technologies could save 300,000 lives approximately. Also, Atkeson, Kopecky, and Zha (2020b) detected four facts regarding the effect of non-pharmaceutical interventions on COVID-19 outbreak. 1-20-30 days after each region experienced 25 cumulative deaths, the growth rate of COVID-19 daily death reduced dramatically. 2-After this period, the daily death growth rate constant around zero. 3-In the first 10 days of pandemic the standard deviation of daily death growth rate decreased dramatically. 4-Based on epidemiological models, these three facts interpreted as the reduction of COVID-19 reproduction number and transmission rate. Also, they argued that ignoring these four facts leads to exaggerate the importance of non-pharmaceutical policies. Avery et al. (2020) provided the critical reviews regarding the coronavirus pandemic models from economist point of view. They claimed that it is not clear whether COVID-19 models help policy makers to implement effective COVIDcontrolling policies in the first months of pandemic, even in some cases like UK it leaded the UK government responded to the spread of the pandemic with delay. They argued that profound data set leads to more accurate COVID modelling. (Also, see Brodeur et al. (2021) ). Stock (2020) provided a framework for economists which used SIR model to understand the impacts of social distancing and containment policies on the development of pandemic and economy. He got the asymptomatic rate using random sampling of the population. To evaluate the economics of shutdown policies he found the most efficient policies to achieve a given transmission rate, β, then determined the path of β in order to compute the trades off between economic cost and lives loss. Moreover, there are several papers which studied the effect of COVID-controlling policies by considering heterogenous population. In the following I summarized the results of several of the main papers, then discussed the main difference between my approach and theirs. Kaplan, Moll, and Violante (2020) integrated an extended SIR model of COVID-19 into a macroeconomic model realistic parameters and job-related and sectoral heterogeneity. They maintained that the economic welfare costs of COVID-19 are large and heterogenous for all combinations of health and economic policies, because of that governments should consider the lives loss costs as well as the fraction of population who endure the upset of economic costs in order to design the COVID-controlling policies. Brotherhood et al. (2020) investigated the importance of the age structure in the COVID-19 outbreak by using an expanded SIR model. They found that imposing more restrictions on young people will extend the duration of pandemic, as well as testing and quarantines save lives even when they only targeted young people. Also, government can raise the welfare of young and old age groups by mixing different policies. Old people can protect themselves during the pandemic. Rampini (2020) scrutinized a sequential framework to elevate COVID-19 interventions policies by considering a heterogeneous population. He divided population into to group: young people who less affected by COVID-19 and work more and old people who more affected by COVID-19 and work less, then figured out lifting lockdown for young people first and the old people later leads to reduction in demand for health care system, death rate, and economy cost of lockdown. In addition, Crossley, Fisher, and Low (2021) examined the UK labor market shocks, and the way individuals and household responded to the first wave of COVID-19 based on the available data regarding first two waves of COVID-19 outbreak. Their results reveled that people with fragile employment condition including those belong to minority ethnic groups, and under 30 years old are affected by labor market shocks significantly. Also, 50 percent of individuals had experienced reduction in their income by 10 percent, and this reduction is very severe for poor households. Arnon, Ricco, and Smetters (2020) evaluated the early lockdown policies using an epidemiological-econometric model. They created daily measures of contact rate and employment and estimate main parameters of the model using an event study framework. The results showed that 1-non-pharmaceutical interventions reduced death toll by 30 percent and saved 33,000 lives, and decline employment by 15 percent, around 3 million jobs in the first three months on COVID-19 outbreak. However, there is small evidence that indicated these policies reduced contact rates nationwide over the same period. 2-Stay at home order is more effective strategy than shutdown policy which targeted businesses. 3-A strict lockdown policies at the first months of pandemic could improve epidemiological and economic consequences in the meantime. Acemoglu, Chernozhukov, et al. (2020) developed a multi-risk SIR model where each compartment divided into three age groups, young, middle-aged, and old in order to capture the heterogenous aspect of COVID-19 outbreak. The results showed that the optimal targeted policies which imposed strict restrictions on old people outperform uniform policies significantly. Specifically, optimal semi-targeted or fully-targeted policies reduce mortality from 1.83% to 0.71%, hence, save 2.7 million lives compared to uniform policies. Another paper which focusses on multi-risk SIR model is written by Gollier (2020) . Specifically, he studies the effect of age-specific confinement and PCR testing policies on incomes and death. He claimed that investing 15% of annual GDP to confine 90% of population for 4 months or confine 30% of population for 5 months could eliminate COVID-19. However, he asserted that paper's results depend on uncertain epidemiological, economics, social, and policy parameters. Glover et al. (2020) paper provided more comprehensive approach regarding heterogenous characteristics of COVID-19 with respect to previous papers. They made a model to determine economic activity and pandemic development. They divided population by young and old age groups, by basic and luxury economic activity, and by health status. Moreover, they analyzed the optimal economic alleviation policy in the case that government can reallocate taxes and transfers. Their results show optimal reallocation and alleviation policies interact, and more modest lockdown policies are optimal when reallocation makes tax distortions. In addition, they claimed that if vaccine available in the first months of 2020, harder but shorter lockdown will be best strategy to control COVID-19. In addition, I study a bunch of related papers which examine the economic impact of COVID-19 including Wu and Olson (2020) I used the adjusted SEQIHR model to model COVID-19 outbreaks. This model is a generalization of the SEIR model of an infectious disease in which a population is divided into six categories of susceptible (S), exposed (E), infected (I), quarantined (Q), isolated/hospitalized (H), and recovered/dead (R). The susceptible group represents uninfected people that can be infected by contacting with infected or exposed individuals. The exposed group refers to individuals who are potentially infective but cannot transmit • I considered the natural rate of birth and death and their effects on the COVID-19 dynamic. • In order to consider endogenous response of policy makers and individuals during the pandemic, I considered some of the main parameters of the model, like contact rate and basic reproduction number over time. • I added the rate of vaccination of susceptible individuals (ν), because at the end of 2020 public vaccination was available in most states. The parameters that I used in my model are summarized in Table 3 . • The susceptible group (S(t)) expands by natural birth (Π) and recovered people who are endangered again with rate (this is because recovered people are not fully immune against COVID-19 reinfection). Moreover, it shrinks by natural death at rate , recovered people because of vaccination at rate ν, and contact by infected people (symptomatic, asymptomatic, quarantined, or isolated) who go to other compartments with transmission rate , , , . In fact, quarantine is not perfect but reduces the contact rate by a factor , and isolation is imperfect, but decreases the contact rate by . • The exposed group (E(t)) increases by new infections of the susceptible group. It is decreased by people becoming infective at rate , being quarantined at a rate , and dying at rate . • The infected group (I(t)) expands by developing clinical symptoms among asymptomatic individuals at rate . It reduces by natural death at rate , COVID-induced death at rate , hospitalization at rate , and recovery at rate . • The quarantined group (Q(t)) generates by susceptible and exposed individuals who are quarantined at rate , and respectively. It shrinks by recovery at rate , hospitalization at rate , and natural death at rate . • The hospitalized group (H(t)) increases by infected and quarantined individuals who are isolated at hospitals at rate and respectively, and diminished by natural death at rate , COVID-induced death at rate , and recovery at rate Based on these assumptions the graph of the adjusted SEQIHR model is depicted in Figure 4 : Moreover, the model assumptions lead to the following system of ordinary differential equations: Since ( ) = ( ) + ( ) + ( ) + ( ) + ( ) + ( ), In addition, death rate induced by the COVID-19 is as follows: Where, = ( + + + ), is contact rate of susceptible individuals with infected people (symptomatic, asymptomatic, quarantined, or isolated). i. Disease-free equilibrium, which is not a useful solution for our problem. ii. Pandemic equilibrium, which is the targeted solution for our system of equations. , which is equal to equation ( 17 ). Hence, the proof is complete. ∎ The basic reproduction number ( 0 ) At time zero (0) > 0, (0) > 0, (0) = (0) = (0) = (0) = (0) = 0. Moreover, the quantities of parameters are mentioned in Table 4 .  Natural death rate The natural death rate for US is 7.37 per 1000 people in 2020. [8] Ν At the end of 2020 only 0.01% of the US population had been fully vaccinated. [9] Modification parameter related to infection from exposed group I set = , based on Gumel et al. (2004) . Modification parameter related to infection from quarantined group I set = , based on Gumel et al. (2004) . Modification parameter related to infection from hospitalized group I set = . , based on Gumel et al. (2004) . The vaccine is 95 percent effective. The data showed between January 17 and August 21, 2021,1 in 5,000 fully vaccinated people experienced a breakthrough infection. More recently, this rate is 1 in 100 fully vaccinated people. [10] Rate of quarantine of exposed asymptomatic individuals Approximately 10% of non-ICU and ICU admissions will die because of Note: This table summarized the parameter's quantities that I use to run the best fit SEQIHR model. I ran the system of equations of the SEQIHR model using the above parameters and got the Figure 5 , which surprisingly fit to the 2020 daily death data of the United States. It should be noted that Atkeson (2021b) used a SEIHR model and got the similar plot. Note: The figure plots the real data (7-Day moving average) and the estimated SEQIHR model based on the Table 2 parameter's quantities. As it is clear, the estimated SEQIHR model (blue line) is a good fit to the real data. Since an adjusted SEQIHR model did a great job to fit the data, in the following section, I used the above fitted model and its parameters' quantities to find economic effect of COVID-19 in the case that there exists heterogeneous population. There are several papers which evaluate the effectiveness on COVID-controlling policies (see Gupta et al. (2020) ; Dave et al. (2021) ; Brzezinski et al. (2020) ; Hsiang et al. (2020) ; Friedson et al. (2020) ). Beside the effectiveness of COVID-controlling policies, one feature which is same among them is that they implemented uniformly. In fact, they treat all people equally and ignore the heterogeneity characteristic of population. Form other hand, one of the main issues of compartmental models is that they do not consider heterogeneity among a population. In a pandemic like COVID-19, the severity of illness and mortality rate are different for different age groups and excluding this crucial characteristic may lead to inaccurate conclusions. Experience with COVID-19 shows how good analysis could help to reduce the deadly effect of a pandemic. By analyzing and implementing good strategies, governments could decrease mortality rate and the negative effect of a pandemic on the economy. I aim to analyze the economic effect of COVID-19 by using a multi risk SEQIHR model. As shown in the previous section, the SEQIHR model is a good fit to the data in that it can capture the nonlinear features of the US daily COVID-induced death toll. Therefore, in the following paragraphs I use this model in the case that we have heterogenous compartments, susceptible, infected, hospitalized, quarantined, and recovered. Based on CDC categorization, I considered the heterogeneous characteristics of these compartments for people who are between 18 and 39 years old (young), between 40 and 64 years old (middle-age) and more than 65 years old (old). I excluded the group with those younger than 17 years old, because the mortality rate for them is very low. In the following I consider multi-risk SEQIHR model to capture the heterogeneity feature of COVID-19. In order to evaluate the economic effect of COVID-19 I use the same methodology introduced by Acemoglu, Chernozhukov, et al. (2020) .However, there are several main differences between their approach and mine. • As it shown in the previous part the SEQIHR model did a good job to fit the real daily death toll, hence I use the multi-risk SEQIHR model, while Acemoglu, Chernozhukov, et al. (2020)used multi-risk SIR model. • Acemoglu et al. 2020 published the paper in May 2020, because of that they had limited data and inaccurate parameters' quantities. However, I have the COVID-19 related data up until December 2021, so that I have more accurate parameters' quantities. Because of that, as it shown in the results part, my results are very close to the real situation compared to Acemoglu, Chernozhukov, et al. (2020) . • Moreover, there are some incorrect assumptions in the Acemoglu, Chernozhukov, et al. (2020) which lead to unvalidated results and somehow far from the truth. For instance, in their paper they mentioned non-ICU patient do not die, while in the reality it is not true. Also, they asserted the proportion of ICU and non-ICU patients do not change over time, though the data show this proportion changed over time. Moreover, they argued that recovered individuals are immune against COVID-19 infection, whilst based on the COVID-19 data there is a possibility that recovered people got infected again. Furthermore, they considered stochastic vaccine arrival, however, we know that the public COVID-19 vaccination was started at late December 2020. Based on the adequate data and more accurate parameters' quantities and correct assumptions I ran the MR-SEQIHR model. As it is shown in the Figure 6 , I divided each compartment of the SEQIHR model which presented in the previous part based on three age groups: 18 and 39 years old (young), between 40 and 64 years old (middle-age) and more than 65 years old (old). Hence, the total population formula denotes in the equation ( 26 ). Where indicates different age groups and t is continuous time; ∈ [0, ⋈). Also, the total population is normalized to unity, hence ∑ = 1. Note: By considering heterogenous population and the SEQIHR model assumptions I depict the multi-risk SEQIHR plot which divided each compartment into three categories: 18 and 39 years old (young), between 40 and 64 years old (middle-age) and more than 65 years old (old). In addition to the relationship between the compartments described previously, different age groups have interactions within each compartment. In order to evaluate the economic effect of COVID-19, beside the SEQIHR Model's parameters that I mentioned in the previous section, I use the following parameters to run MR-SEQIHR model. • denotes the workers' production of age group i in the absence of lockdown, otherwise the production is zero. w can represent the wage of employees too. • designates cost of death in age group i other than production lost when employees are dead because of COVID-19. • refers the share of recovered individuals in age group i who allowed to work. • indicates the interest rate in order to calculate the present value of monetary and non-monetary costs of COVID-induced death. Susceptible (S), exposed (E), infected (I), quarantined (Q), isolated/hospitalized (H), and recovered/dead (R) dynamics are similar to the equations ( 1 ) to ( 6 ) , Which explained in the previous section. I analyze the economic effect of COVID-19 through employment; hence I consider some assumptions in order to get the employment equation. These assumptions are as follows. • The fraction of susceptible individuals of each age group who allow to work is (1 − − ( )). • The fraction of exposed individuals of each age group who allow to work is (1 − − ( )). In addition, the fraction of exposed individuals of each age groups go to quarantined and infected compartments with rates , respectively, so that they are not allowed to work. • The fraction of infected individuals of each age group who allow to work is (1 − − ( )). Moreover, the fraction of infected individuals of each age groups go to hospitalized compartment with rate or die because of COVID-19 with rate , so that they are not allowed to work. • Based on the input and output of quarantined compartment, the fraction of quarantined individuals of each age group who cannot work is (1 − ). • Based on the input and output of hospitalized compartment, the fraction of hospitalized individuals of each age group who cannot work is (1 − ). • The fraction of recovered individuals of each age group who allow to work is (1 − − ( )). In addition, fraction of recovered individuals in each age group are allowed to work. Therefore, based on the above assumptions we could write the employments equation as follows: Furthermore, the planner's objective is controlling lockdown, { ( )} , for ∈ [0, T), in order to minimize the expected present value of social costs. Then, we could write the objective function as follows: Note that ( − ( )) denotes monetary costs of death and ( ( ) + ( )) represents nonmonetary costs of death. I consider the period before arriving vaccine, hence by substituting equation ( 27 ) in equation ( 28 ), we can rewrite the objective function as follows: Where ̂= + indicates the total cost of death. Since SEQIHR did a good job to fit the real data, the parameters' quantities which I used to run SEQIHR in the previous section are the same. Other required quantities for running MR-SEQIHR are as follows: • • I assume that the old people produce nothing, = 0, and young and middle-aged workers' production equal 1, = = 1. [15] • Since ( ) represents the severity of lockdown, I assume ̅̅̅ = 1, and ̅̅̅ = ̅̅̅̅ = 0.7. Moreover, in the case of uniform policy I assume ̅ = 0.7. (Alvarez et al). • Based on the CDC report, the COVID-induced mortality rate of young is 0.000315, the mortality of middle-age is 0.00132, and the mortality rate of old is 0.0030. [16] • As in Acemoglu, Chernozhukov, et al. (2020) , I set non-monetary cost of death, = − − Δ . Where Δ denotes remaining work time, so that Δ = 15 × 365 and Δ = 0. Also, daily interest rate, = 0.01 365 . Moreover, I consider = 20 in the baseline model, which means non-monetary cost of death is 20 times the annual economic contribution of a representative worker. • Acemoglu, Chernozhukov, et al. (2020) consider stochastic vaccine arrival, while we know that the first dose of vaccine was available for public at late December 2020. Because of that I just consider the situation that we have deterministic vaccine arrival. In the baseline model, I consider T=365, which implies it takes around a year the first doses of vaccine to be available publicly. Acemoglu, Chernozhukov, et al. (2020) used pareto frontier to show the trade-off between COVID-19 induced life loss and GDP loss as an indicator of economic loss of the United States. They show this relationship in the Figure 7 . As it is clear after a certain point there is an ascending trend in the pareto frontier which indicates more GDP and lives lost in the absence of any COVID-19 controlling policies. In addition, the optimal targeted curve is closer to the "bliss point", the origin, than the uniform curve. Note: This figure represents the pareto frontier of optimal uniform and targeted COVID-controlling policies. As it is clear the optimal targeted policies which treated distinct age groups differently could reduce the output loss and death rate much better than uniform policies which treat population uniformly, because of that the optimal targeted curve is closer to the "bliss point", the origin, than the uniform curve. Acemoglu, Chernozhukov, et al. (2020) They argue that when we have uniform policy which means all the population treated equally for implementing lockdown policies, the death rate and GDP loss will be 1.83 percent and 23.4 percent respectively at the end of 2020. However, targeted policies and even simi targeted policies which treated different age groups differently and impose strict lockdown on old individuals could reduce the fatality rate and GDP loss compared to uniform policies. Specifically, the optimal targeted policies that contains strict lockdown on oldest group can reduce the fatality rate and GDP loss to 1 percent and 12.8 percent respectively compared to uniform lockdown. However, based on the World bank data, [17] the GDP growth rate of united states in 2020 is -3.5 percent, while this indicator was 2.2 percent in 2019. Comparing actual statistics with Acemoglu, Chernozhukov, et al. (2020) results indicate a significant difference between them. Even, optimal targeted policies which computed 12.8 percent decrease in GDP is far from the reality. Moreover, based of the National Center for Health Statistics (NCHS) report, [18] which mentioned previously, the COVID-19 induced-death rate is 0.1 percent which is far different from Acemoglu, Chernozhukov, et al. (2020) results. As previously discussed, wrong assumptions, inaccurate parameters, and limited data may lead to these incorrect results. In order to get the precise results, I use the actual parameters and good fitted SEQIHR model. Figure 8 represents pareto frontier of GDP loss and death rate under distinct COVID-controlling policies for different quantities of . Like figure 7 the origin, where there is zero death rate and GDP loss, indicates bliss point. The convex shape of the frontiers indicates the decreasing returns to scale of getting one goal in the expense of other. The red point refers the exact condition of US during 2020 where the GDP loss is 3.5 percent and death rate is 0.1 percent based on the real data. In addition, the blue dotted line represents the uniform COVID-controlling policies which treated all people uniformly. Moreover, the green dotted line represents the targeted COVID-controlling policies which treated each age group differently. Note: The figure plots the pareto frontier of targeted and uniform COVID-controlling policies plus the exact condition of death rate and GDP loss based on the real data. The blue dotted line represents the uniform COVID-controlling policies, the green dotted line depicts the targeted COVID-controlling policies, and the red dot refers to exact condition of the US based on the real data. As it is clear from Figure 8 , the exact condition of US is close to optimal uniform policies. Also, GDP maximizing outcome occurred in the southeast part of each frontier. Then, at the GDP maximizing point of the optimal uniform policy frontier, the GDP loss is 2 percent and death rate is 0.18 percent. However, at the GDP maximizing point of the optimal targeted policy frontier, the GDP loss is 1 percent and death rate is 0.09 percent. More importantly, with the same level of GDP loss of exact condition, 3.5 percent, optimal targeted policy could reduce the death rate to 0.03 percent. Declining death toll by 0.07 percent means for the same percent of GDP loss if we implement optimal targeted policy, we could save 2/3 lives that is dead because of COVID-19. Nearly, 378,000 persons dead because of COVID-19 during 2020, therefore reducing death rate to 0.03 percent mean saving around 280,000 lives, which is huge. All in all, the adjusted SEQIHR did a great job to show the dynamic of COVID-19 over time, specifically it is good fit to the COVID-induced daily death data of United States in a way that it could capture the nonlinearities of the data very well. Because of that I used this model to estimate the economic impact of COVID-19 in the United States. Since risk of hospitalization, infection and death are different for various age groups, I used multi-risk SEQIHR model to evaluate lockdown policies. I considered the heterogeneous feature of COVID-19 by dividing each compartment of SEQIHR model into three categories: individuals who are between 18 and 39 years old (young), persons who are between 40 and 64 years old (middle-age) and people who are more than 65 years old (old). Since the mortality rate for those younger than 17 years old is very low I excluded them, then adding several parameters to the SEQIHR model and ran the model. Based on the actual data, the GDP loss and death rate for the United States during 2020 were 3.5 and 0.1 percent. However, the paper's results show that optimal targeted policy which imposed more severe restrictions on old people could reduce mortality rate to 0.03 percent with the same level of GDP loss of actual data, 3.5 percent. Compared to actual data, the targeted policy could save 280,000 lives. Gating criteria are the data-driven conditions each region or state should satisfy before proceeding to a phased opening The data related to the number of COVID-19 positive cases by age group The data related to the number of COVID-induced death by age group Based on the National Center for Health Statistics (NCHS) report, the provisional general fertility rate (GFR) for the United States in 2020 was 55.8 births per 1,000 women aged 15-44. The NCHS report available at A multi-risk SIR model with optimally targeted lockdown Optimal adaptive testing for epidemic control: combining molecular and serology tests Azarakhsh Malekian, and Asuman Ozdaglar. 2020. Testing, voluntary social distancing and the spread of an infection Bayesian Estimation of Epidemiological Models: Methods, Causality, and Policy Trade-Offs Epidemiological and economic effects of lockdown How deadly is COVID-19? Understanding the difficulties with estimation of its fatality rate What will be the economic impact of COVID-19 in the US? Rough estimates of disease scenarios Behavior and the Dynamics of Epidemics A parsimonious behavioral SEIR model of the 2020 COVID epidemic in the United States and the United Kingdom Economic benefits of covid-19 screening tests Behavior and the Transmission of COVID-19 Estimating and forecasting disease scenarios for COVID-19 with an SIR model Four stylized facts about COVID-19 Policy implications of models of the spread of coronavirus: Perspectives and opportunities for economists Covid-induced economic uncertainty Nonlinear production networks with an application to the covid-19 crisis Keynesian Production Networks and the Covid-19 Crisis: A Simple Benchmark Reopening scenarios Understanding Coronanomics: The economic implications of the coronavirus (COVID-19) pandemic An seir infectious disease model with testing and conditional quarantine The challenges of modeling and forecasting the spread of COVID-19 An introduction to compartmental modeling for the budding infectious disease modeler Modern infectious diseases: Macroeconomic impacts and policy responses The impact of COVID-19 on US firms Per Krusell, and Jonna Olsson. 2020. Integrated epi-econ assessment Economics in One Virus: An Introduction to Economic Reasoning through COVID-19 Measuring sectoral supply and demand shocks during COVID-19 A literature review of the economics of COVID-19 An economic model of the Covid-19 pandemic with young and old agents: Behavior, testing and policies The covid-19 pandemic: government vs. community action across the united states 2020. The US labor market during the beginning of the pandemic recession The economic burden of COVID-19 in the United States: Estimates and projections under an infection-based herd immunity approach Causal impact of masks, policies, behavior on early covid-19 pandemic in the US COVID-19 scenarios for the United States The heterogeneous and regressive consequences of COVID-19: Evidence from high quality panel data When do shelter-inplace orders fight COVID-19 best? Policy heterogeneity across states and adoption time Epidemic models: their structure and relation to data The macroeconomics of epidemics Internal and external effects of social distancing in a pandemic Restarting the economy while saving lives under Covid-19 Estimating and simulating a SIRD model of COVID-19 for many countries, states, and cities Transitioning out of the coronavirus lockdown: A framework for evaluating zone-based social distancing Did California's shelter-inplace order work? Early coronavirus-related public health effects Estimating parameters in stochastic compartmental models using Markov chain methods DETERMINISTIC AND STOCHASTIC MODELS OF INFECTIOUS DISEASE: CIRCULAR MIGRATIONS AND HIV TRANSMISSION DYNAMICS Health versus wealth: On the distributional effects of controlling a pandemic Cost-benefit analysis of age-specific deconfinement strategies Macroeconomic implications of COVID-19: Can negative supply shocks cause demand shortages? Modelling strategies for controlling SARS outbreaks Tracking public and private responses to the COVID-19 epidemic: evidence from state and local government actions Trading off consumption and covid-19 deaths The type-reproduction number T in models for infectious disease control The mathematics of infectious diseases The effect of large-scale anti-contagion policies on the COVID-19 pandemic The great lockdown and the big stimulus: Tracing the pandemic possibility frontier for the US A contribution to the mathematical theory of epidemics Contributions to the mathematical theory of epidemics. II.-The problem of endemicity Contributions to the mathematical theory of epidemics. III.-Further studies of the problem of endemicity Optimal control of prevention and treatment in a basic macroeconomic-epidemiological model The economic impact of COVID-19 The global macroeconomic impacts of COVID-19: Seven scenarios Behavioral dynamics of COVID-19: Estimating under-reporting, multiple waves, and adherence fatigue across 92 nations Sequential lifting of COVID-19 interventions with population heterogeneity Why is it difficult to accurately predict the COVID-19 epidemic? Quantitative economics with Julia Sensitivity to model structure: a comparison of compartmental models in epidemiology Generalized reproduction numbers, sensitivity analysis and critical immunity levels of an SEQIJR disease model with immunization and varying total population size Data gaps and the policy response to the novel coronavirus A bayesian updating scheme for pandemics: estimating the infection dynamics of covid-19 Transmission Dynamics of COVID-19 under Differential Levels of Masking and Vaccination Products of Compartmental Models in Epidemiology Pandemic risk management in operations and finance Optimal quarantine and isolation control in SEQIJR SARS model Understanding Concerns, Sentiments, and Disparities Among Population Groups During the COVID-19 Pandemic Via Twitter Data Mining: Large-scale Cross-sectional Study