key: cord-0078008-um90mt4b authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj title: Correspondence on “Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19” date: 2022-05-11 journal: J Stroke Cerebrovasc Dis DOI: 10.1016/j.jstrokecerebrovasdis.2022.106556 sha: 8dc8236d6cec980a6600c71d83e71392e2383fa0 doc_id: 78008 cord_uid: um90mt4b nan . Since the basic Wirchow's triad is the accepted explanation for the pathophysiological process of the stroke, we agree that there should be no difference in the pathogenesis of the stroke in cases with and without vaccination history. It's usually difficult to find a link between immunization and stroke. The current observation study lacks data on the vaccine recipients' pre-vaccination thrombohemostatic condition, therefore it cannot rule out the effect of underlying disease. Furthermore, a vaccine recipient may have a coexisting disease that causes thrombohemostatic problems. It is important to emphasize that not all Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19 Thrombosis After Adenovirus-Vectored COVID-19 Vaccination: A Concern on Underlying Illness. Mungmunpuntipantip R, Wiwanitkit V thrombohemostatic issues in COVID-19 vaccine recipients are caused by the vaccine [2] .Funding : none Conflict of interest: none