key: cord-0077085-gh3ckabx
authors: Camastra, Giovanni; Ciolina, Federica; Corsi, Maria Pia; Gemmiti, Maria Paola; Arcari, Luca
title: Monitoring the evolution of myocarditis following COVID-19 mRNA vaccination with serial cardiac magnetic resonance imaging
date: 2022-04-13
journal: Int J Cardiovasc Imaging
DOI: 10.1007/s10554-022-02603-1
sha: 162198b998a8ead89f14b7496ebf259a17a73cb0
doc_id: 77085
cord_uid: gh3ckabx

nan

With the ongoing vaccination campaign against coronavirus disease-19 (COVID-19), cases of myocarditis associated with mRNA vaccination have been increasingly recognized. We describe here the case of a young male patient who developed chest pain and increased troponin 4 days after vaccination with Pfizer-BioNTech COVID-19 vaccine. Coronary angiography revealed patent coronary arteries and in the setting of clinically suspected myocarditis the patient was referred for cardiac magnetic resonance (CMR). CMR images showed normal biventricular function, edema in the inferior and infero-lateral left ventricular (LV) wall ( Fig. 1 , T2-STIR imaging in panel A, T2 mapping in panels B and C) with midwall fibrosis within the same region as indicate by increased signal in native T1 mapping ( Fig. 1 , panel D), late gadolinium enhancement (LGE) (Fig. 1 , panel E) and reduced signal in post-contrast T1 mapping images ( Fig. 1 , panel F). All these findings were consistent with acute myocarditis. A further examination was scheduled at 6 months, to assess myocardial remodeling after the acute phase and evaluate the need for adjunctive treatments. The follow-up examination showed absence of edema and a significant reduction of LGE extension (Fig. 2) . This result suggests the ongoing resolution of the disease and its benign course. Large cohorts of patients with myocarditis after mRNA vaccination for COVID-19 revealed the common occurrence of mild forms with benign outcome [1] , albeit severe cases requiring intensive management might occur. Translating the approach applied to more classic forms of myocarditis [2] , serial CMR might be useful to provide adjunctive clinical information and an improved risk-stratification.

* Luca Arcari luca_arcari@outlook.it 

The authors declare no competing interests. 

2021) myocarditis after Covid-19 vaccination in a large health care organization

Prognostic value of repeating cardiac magnetic resonance in patients with acute myocarditis