key: cord-0071098-nnxm5tcp
authors: Al Sulmi, Eman S; Al Yousef, Manar M; Almuslim, Jenan A; Al Muslim, Rawan A; Amailo, Zahra A; Alabbad, Fatimah A
title: Awareness, Perceptions, and Desirability of Epidural Analgesia Among Pregnant Women in King Fahad University Hospital, Al Khobar
date: 2021-12-03
journal: nan
DOI: 10.7759/cureus.20146
sha: 2ee7a463105eb6d91c8154304f3226b0698e18c8
doc_id: 71098
cord_uid: nnxm5tcp

Background: Childbirth is a normal life event that is considered to have the most severe pain faced by women in their lifetime. However, this pain can be managed in many ways such as using epidural analgesia (EDA). Objective: This study focuses on assessing the awareness, perceptions, and desirability of EDA among pregnant women at King Fahad University Hospital (KFUH), Al Khobar. Methods: A cross-sectional study was conducted at KFUH in Al Khobar, Eastern Province of Saudi Arabia. The study took place from November to December 2020 by using a pre-designed questionnaire developed by the researchers based on a thorough literature review of prior studies. A total of 209 pregnant females participated in the study. The study included all pregnant women attending antenatal clinics and the emergency room at KFUH and we excluded postpartum women from the study. Results: A total of 209 pregnant women participated in this two-month study and completed the questionnaire. The majority of women were between the age of 30-35 years old (33%), while a few (16%) were less than 24 years. The patient’s perception was found to be significantly influenced by age and household income. On the other hand, awareness of EDA complications and desirability was seen to be associated with income. Conclusion: Study results demonstrate that the majority of pregnant women were aware, as well as had a positive perception and desirability toward using EDA for labor pain. On the other hand, pregnant women who had a lack of awareness and perception toward EDA may suffer more from labor pain, which will negatively affect their birth experience and may make it less enjoyable. Therefore, education about different types of analgesia, especially EDA, should be included in an antenatal care program.

Childbirth is a normal life event that is considered to have the most severe pain faced by women in their lifetime. This pain is manageable and can be influenced by medications and many other factors including age and psychological factors such as anxiety, emotional support, educational level, culture, and ethnicity [1] . Epidural analgesia (EDA) is considered an effective measure for labor pain relief if administered timely [2] . EDA allows women to rest if the labor is prolonged, and remain an active participant in the child birthing [3] . If instrumental delivery is needed, EDA will help to decrease the discomfort, and if a cesarean section (CS) is required it allows to stay awake during the procedure. Moreover, using EDA helps to avoid opioidinduced maternal and neonatal respiratory depression [4] . A systematic review study, conducted in 2020, concludes that the early administration of EDA does not increase the risk of proceeding CS, prolong the second stage of labor, or impact maternal and neonatal outcomes [5] . American College of Obstetricians and Gynecologists (ACOG) recommends the use of analgesia in labor when possible [6] . The National Institute for Clinical Excellence has encouraged patients' education on the availability and effectiveness of labor pain options, hence, ensuring that pregnant women have the choice of adequate pain management in labor [7] . EDA is proven an effective and safe option for optimal labor pain management [2, 4] . Therefore, it is imperative to assess the perception and acceptability of our population to EDA in order to educate and correct misconceptions. Therefore, we conducted this study to assess pregnant women's awareness, perception, and desirability of the usage of EDA, and to identify the reasons for giving birth without epidural analgesia.

The study aims to assess the awareness, perception, and desirability of epidural analgesia among pregnant women, identify the reasons for giving birth without epidural analgesia, and the predictors for epidural analgesia requests among pregnant women at a single center in Saudi Arabia. With the approval (IRB-UGS-2020-01-291) of Imam Abdulrahman bin Faisal University IRB, a cross-sectional study was conducted at King Fahad University Hospital (KFUH) in Al Khobar, Eastern Province of Saudi Arabia using a selfadministered questionnaire. The questionnaire is divided into eight sections including demographic characteristics, frequency of EDA usage and history of exposure, experience of labor, perception of EDA, awareness of EDA, awareness of complications of EDA in labor, desirability, and source and adequacy of the information. Both paper-based and electronic versions of the questionnaire, according to patients' convenience, were offered to all pregnant women attending antenatal clinics and obstetrics' emergency room excluding postpartum women. With the corona virus disease 2019 (COVID-19) restrictions and reduction in number of clinic visits to maintain social distancing, an average of seven women per day was expected to agree to participate in the study. Thus, 308 women are expected to participate in the two months period. The questionnaire was developed by the researchers based on a thorough literature review of prior studies [2, 8, 9] . It was developed in English then translated to Arabic. The English version was provided for non-Arabic patients. A pilot study for both the Arabic and English version validation was performed on 10 participants who weren't included in the study and changes were made accordingly. The data collectors explained the study to candidates, after agreeing on participation, and signed consent was taken from all participants before they were given the self-administered questionnaire to complete.

The data were presented as frequency tables for categorical variables. Chi-squared test was used to compare demographics as an independent variable (Age, Nationality, Income, and Parity) with perception, awareness, and desirability of EDA as dependent variables. The questionnaire was assessed and showed that Cronbach's Alpha is 0.859 which means it is statistically reliable.

The result in terms of awareness, perception and desirability, were interpreted using the mean as follows: from 1 to 2 considered to be positive, and from 2.1 to 3 considered to be negative. Results with p-values below 0.05 were considered to be statistically significant. All data analyses were performed in IBM SPSS Statistics for Windows, Version 26.0 (Released 2019, IBM Corp, Armonk, New York).

For a two-month study period, a total of 209 pregnant women participated in this study with a participation rate of 67.5%. Some of the participants completed the questionnaire but there were also some missing data. The majority of women were between the age of 25-35 years old (62%) and predominantly Saudi (80.6%). Moreover, approximately half of the respondents' income was less than 8000 Saudi Riyal (SAR) (49.8%). The majority (80.6%) of our participants had given at least one birth in the past, and only 19.3% were nulliparous. Table 1 gives the details. Out of the 209 women who participated in the questionnaire, only 68 (32.7%) used epidural analgesia in their previous labor. Fifty-two participants reported a negative experience in the form of either developing side effects or complications such as inadequate analgesia and back pain (39.7% and 36.8%, respectively). On the other hand, 76.8% of women who had used epidural analgesia reported a satisfactory experience. Only 28.6% of the women who did not use epidural analgesia in the previous labor are willing to use it in the future. The reasons for rejection were mostly due to fear of side effects (40%). See Table 2 . 

Although pregnant women who already used EDA reported positive perception, awareness, and awareness of complications of EDA, the relation between previous use of EDA with the perception, awareness, and awareness of complications of EDA was statistically insignificant (p-value = 0.503, 0.616, 0.335 respectively).

Around 56% of participants were worried about losing the ability of sensation when they need to push; however, half of them have a positive perception of EDA and agreed that the benefits outweigh the risks of potential side effects. See Table 3 . The patient's perception is significantly associated with age (p-value 0.049). In other words, the majority of women with a positive perception toward EDA were in the age group of 30-35 years (33.7%). Similar results were found between income and perception, which were statistically significant; participants with low income (<8000SAR) showed more positive perceptions regarding the use of EDA for labor pain. However, parity and nationality did not significantly affect the women's perception of EDA. See Table 4 . Awareness of EDA complications was assessed by asking about the common complication of EDA ( Table 6) .

Most of the women (n=120; 57.4%) agreed that it causes back pain followed by headache (n=96; 45.9%), low blood pressure (n=77; 36.8%), increased intervention in labor (n=63; 30.1%), and finally prolongation of second-stage labor and effect on the unborn baby (n=61; 29.2%). There was positive awareness of EDA complications, which was associated with income. The result revealed that 55% of participants' income was less than 8000SAR. The p-value result from studying the association between income and awareness of complications of EDA was found to be significant at 0.012. On the other hand, data showed that there is no significant association between age, nationality, parity, and awareness of EDA complications ( In this study result, there was a strong association between income and desirability to take EDA. As shown in Table 4 , pregnant women with income less than 8000SAR (p-value 0.009) were more willing to use EDA than the others. On the other hand, there was no significant association between age, nationality, parity, and desirability to use EDA. The end result revealed that most of the pregnant women in this study (63.6%) had positive desirability to take EDA.

Most women (n=71; 34%) reported family and friends as their source of information about EDA, followed by doctors (n=60; 28.7%), media (n=56; 26.8%), nurses (n=9; 4.3%), and antenatal class (n=9; 4.3%).

In addition, pregnant women who received information from the antenatal class have better perception and awareness of EDA compared to those receiving information from other sources (100%, 88.9% respectively). However, this relation was statistically insignificant (p-value 0.125, 0.947 respectively).

Our study showed that the majority of participants (85.6%) were aware of the EDA. A similar result was found in a study done in Riyadh, which showed that the participants were knowledgeable regarding EDA [10] .

In contrast, a study done in Abu Dhabi in 2015 showed that women are not well informed about EDA and so they do not consider it [11] . Moreover, there was no relation found between the awareness of EDA and age, nationality, income, and parity (p-value 0.544, 0.113, 0.349, 0.702 respectively).

Of the women in our study population, 80.4% were aware about the complication of using EDA for labor pain. This was contrary to study findings by Ezeonu et al., which showed that majority of women (72.41%) had no knowledge about the complication of EDA [2] . We found that the majority of women agreed that EDA causes back pain and headache. This finding is similar to what was found in a Saudi study that was done in 2018 [12] , unlike the conclusion of another study that was done among women from Australia and the United Kingdom, where they found that women in Australia have greater awareness about epidural infection and nerve damage [13] .

The overall perception regarding EDA was positive in 87.6% of participants, which is higher by approximately 37% than the result of a Saudi study conducted in 2018 [12] . This could indicate that the population is becoming more educated toward EDA. A study in Townsville, Australia, showed that 44% of participants disagreed that they would never use EDA, while 56% were unsure about whether EDA helps with labor progression, and 63% agreed that they were worried about the possibility that it will affect their ability to walk and move around [8] . These results were similar to our study with a small difference in the percentages ( Table 3) . In two previous studies, it was seen that most of the participants in Saudi Arabia and Pakistan were concerned about backache associated with EDA [14, 12] . Similarly, in this study, back pain if using EDA was the biggest concern.

When it comes to EDA desirability, only 63.6% of pregnant women showed willingness to take EDA. In a study done in Ludhiana, desirability and willingness to take EDA (96.7%) were significantly higher than our findings [2] . Interestingly, we found that pregnant women with income less than 8000SAR (p-value 0.009) were more willing to use EDA. We also found that age, nationality, and parity did not affect desirability to have EDA in labor. In contrast, a previously published study in India found that unwillingness and desire for epidural analgesia were closely linked to the gravida status [15] .

Logically, we found that pregnant women who had a satisfactory experience with EDA (36, 67.9%) are more willing to use it again compared to those with unsatisfactory experience (p-value 0.000). However, only 28.6% of pregnant women who had not used EDA in the past would like to use it in future. In addition, the reasons for low desirability for EDA were due to fear of side effects. This end result is similar to another study done in Nigeria, which concluded that 95% of the respondents who took EDA were satisfied with the experience and desired to take it again [2] . However, only 70% of those who had not used EDA expressed the desire to use it. Some of the reported causes for the lack of desirability to using EDA includes fear of side effects, cost, and experiencing natural labor.

The most common source of information regarding EDA was the family and friends (34%) followed by physicians (28.7%), media (26.8%), nurses (4.3%), and antenatal class (4.3%). This result is similar to a study done in Saudi Arabia where they found that the most common source of information regarding EDA was friends and relatives (67%), previous labor experience (16%), media (8%), and books (2%) respectively [12] . Only 39.1% of participants agreed that they have received adequate information on various forms of pain relief in labor including EDA. Therefore, antenatal care programs should include educational sessions about different types of pain relief during labor including EDA.

Using the result of this research, an antenatal care program should include a discussion between pregnant women and a certified healthcare provider about EDA, its side effects, potential complications and alternatives.

As the study was conducted between November and December 2020, the number of patients was restricted due to the COVID-19 pandemic. Moreover, this study took place in a tertiary hospital where the cases were more complicated; therefore, the participants were more knowledgeable. A suggestion is to conduct further research among pregnant women from different levels of healthcare systems including primary, secondary, and tertiary health care facilities.

In this study, most pregnant women received their sources of information from family, friends, or social media. This could influence the awareness, perception, and desirability of EDA. Therefore, we recommend giving antenatal educational programs for pregnant women who attend the clinic about possible pain management in labor including EDA. In addition, healthcare providers should put more effort on social media and provide the community with evidence-based information about possible methods of pain relief during labor since social media has a great influence in the community these days.

This study highlights the importance of labor pain management policies and patients' education. Although our study results demonstrate that the majority of pregnant women were aware of EDA and also had a positive perception and desirability toward using EDA for labor pain, there is still a good number of women who have a lack of awareness and perception toward EDA. These women may have more intense labor pain that will negatively affect their labor experience and make it less enjoyable. Therefore, having a national policy and guidelines on labor pain management is crucial to improving labor experience and maternal care in Saudi Arabia. Furthermore, education about different types of labor pain analgesia, especially EDA, should be included early in an antenatal care program.

Human subjects: Consent was obtained or waived by all participants in this study. Imam Abdulrahman bin Faisal University IRB issued approval IRB-UGS-2020-01-291. The application was reviewed and approved at Imam Abdulrahman bin Faisal University IRB through an expedited review on Tuesday, October 20, 2020. . Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue.

In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Analgesia for labour: an evidence-based insight for the obstetrician

Perceptions and practice of epidural analgesia among women attending antenatal clinic in FETHA

Knowledge and attitude regarding epidural analgesia among expectant mothers

Epidural analgesia during labor

Concerned topics of epidural labor analgesia: labor elongation and maternal pyrexia: a systematic review

ACOG Committee Opinion #295: pain relief during labor

Intrapartum care for healthy women and babies. National Institute for Health and Care Excellence

Women's epidural decision-making in labour: a Townsville perspective

Lebanese women‫׳‬s awareness and attitude toward epidural anesthesia during labor

Women's awareness and attitude toward epidural analgesia

A survey of women's views of epidural analgesia in the Middle East

Knowledge and attitude of Saudi women toward painless labor, and misconception about the risks and complications

Complications of obstetric regional analgesia: how much information is enough?

A survey on perception of epidural in labouring women

Epidural analgesia during labor: attitudes among expectant mothers and their care providers