key: cord-0069234-1f014o19
authors: Corrêa, Diogo Goulart; da Cruz, Luiz Celso Hygino
title: Reply to the letter to the editor: “impact of SARS-CoV-2 vaccines on the nervous system”
date: 2021-11-03
journal: Clin Imaging
DOI: 10.1016/j.clinimag.2021.10.016
sha: c562c13ad9ecbea4db756f345c3b7a2b6c9581e9
doc_id: 69234
cord_uid: 1f014o19

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debate on the topic. After carefully reading the letter, we understand that the authors concerns are based on the fact that some of the clinical investigations performed on the patients were not expressly included in the body of the text.

However, due to this opportunity, we can expose more information about the clinical cases.

Patient 1 were a 64-year-old man, who presented an ischemic stroke two days after vaccination. He was hospitalized in an intensive care unit, having been monitored with a long-term electrocardiogram, which did not reveal any arrhythmia. As we indicated in the paper, the hemogram, including the red blood cells and platelets counts, was normal. During hospitalization and clinical follow-up, the patient did not present any signs or symptoms of heart failure. In addition, the electrocardiogram and the echocardiogram were normal. The echocardiogram did not show any sign of systolic dysfunction or atrial or intraventricular thrombus. Also, the troponin serum level was normal. A brain magnetic resonance angiography was also normal. The patient remains under outpatient follow-up, with no evidence of cardiac symptoms, and a new echocardiogram was normal. Therefore, the medical team considered that there was no need to perform a heart magnetic resonance imaging (MRI) to rule out myocarditis.

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Compliance with ethical standards Declarations of interest: none. Funding: No funding was received for this study

Ethical approval: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards