key: cord-0037863-5i6ne0zh authors: nan title: The Twentieth International Conference on Antiviral Research date: 2007-02-22 journal: Antiviral Res DOI: 10.1016/j.antiviral.2007.01.008 sha: 24a43e36f66f731ab8d72e44779262e220e86a1d doc_id: 37863 cord_uid: 5i6ne0zh nan The Society was organized in 1987 as a non-profit scientific organization for the purpose of advancing and disseminating knowledge in all areas of antiviral research. To achieve this objective, the Society organizes an annual meeting. The Society is now in its twenty first year of existence, and has about 600 members representing 30 countries. For membership application forms or further information, please contact Dr. Joseph M. Colacino, Secretary, ISAR; Vice President, Drug Discovery, PTC Therapeutics, Inc., 100 Corporate Court, south Plainfield, NJ 07080, USA, Phone +1 908 222 7000x131; fax +1 908 222 0567; E-mail jcolacin0@ptcbio.com. Membership application forms will also be available at the Conference Registration desk, or from our website http://m114.phrm.cf.ac.uk/isar/node/1. 00 Break 10:30 4. Mutations in the RNaseH Region Observed in the HIV-1 of Antiretroviral Treatment (ART) Experienced Patients 10:45 5. Involvement of New Mutational Pattern in HIV-1 gp41 in T-20 Treatment Stefano Aquaro 1,2 , Valentina Svicher 2 , Roberta D'Arrigo 3 , Mario Santoro 2 , Giovanni Di Perri 4 , Sergio Lo Caputo 5 Institute, Rome, 14:15 22. Novel 4 -Azido-2 -Deoxy-Nucleoside Analogs Are Potent Inhibitors of NS5B-Dependent Characterization of the Intracellular Metabolism of ␤-d-2 -Deoxy-2 -Fluoro-2 -C-Methyl-Cytidine and the Inhibition of HCV Polymerase NS5B by its 5 -Triphosphate Species Han Ma GL59728: A Potent Allosteric Inhibitor of the HCV NS5b RNA Dependent RNA Polymerase With Excellent Pharmacokinetic Properties Christopher Roberts Potent HCV NS5B Polymerase Inhibitors Derived From 5-Hydroxy-3(2H)-Pyridazinones: Part 1. Exploration of Pyridazinone 4-Substituent Variation Y The Combination of Anti-Poxvirus Compounds ST-246 and TTP-018 are synergistic In Vitro Yali Chen 1 , Chris Harver 1 , Guang Yang 1 Selective Phosphorylation of Antiviral Drugs by Vaccinia Virus Thymidine Kinase Emma Harden 1 Korea Research Institue of Chemical Technology 144. Substrate Specificity and Molecular Modelling of Feline Herpesvirus-1 Thymidine Kinase Islam Mohammad 1 UK 145. Chemical Stability and Intracellular Metabolism of 1-(S)-[3-Hydroxy-2-(Phosphonomethoxy)Propyl]-5-Azacytosine Lieve Naesens 1 , Graciela Andrei 1 , Ivan Votruba 2 , Marcela Krecmerová 2 Flemingovo nam. 2, 166 10 Prague 6, Czech Republic 146. Influence of Substitutes in the Central Phenyl Ring of Capsid Function Inhibitors on Anti-Coxsackievirus B3 Stivity Michaela Schmidtke 1 Efficacy of 5-halogenated 2'-deoxyuridines on vaccinia virus thymidine kinase positive and negative strains, and influence of cell type on antiviral potency Donald Smee University of Alberta, Canada; 2 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Russia 149. Enhanced Potency and Efficacy of 29-mer shRNAs in Inhibition Crosstalk Between Scavenger Receptors (SR-A) and Toll-like Receptors (TLR) Results in Rapid Pro-Inflammatory Cytokine Differentiation in Monocytes Exposed to Cytomegalovirus (CMV) Hooi Yew 1 09:15 30. The Imidazopyrrolopyridine Analogue AG110 is A Novel, Highly Selective Inhibitor of Pestivirus Replication and Targets the Viral RNA-Dependent RNA Polymerase AFMB-UMR 6098, France; 4 University of Tours, France; 5 University of Innsbruck, Austria; 6 University of Auvergne, France 09:30 31. Nitazoxanide is an Effective Antiviral Agent Against Both HBV and HCV Replication In Vitro Brent Korba 1 , Muller Abigail 1 Efficacy of Cationic Lipid-DNA Complexes (CLDC) on Hepatitis B Virus in Transgenic Mice John D. Morrey 1 , Neil E. Motter 1 , Brandon Taro 1 , Fairman Jeffery 2 1 Institute for Antiviral Research Structural Basis for the Expanded Substrate Specificity of Vaccinia Virus Thymidine Kinase: Insight from the Crystal Structure Mark Prichard 1 Vaccination as an Antiviral Strategy for Control of Cytomegalovirus (CMV) Disease: A Vectored Vaccine Approach Targeting the UL83 (pp65) Homolog Protects Against Congenital CMV Disease in the Guinea Pig Model Mark Schleiss 1 JuvImmune is a Novel Vaccine Adjuvant that Enhances Protection of Mice from Lethal HSV-2 Infection Following Immunization Jane Strasser 1 , Rhonda Cardin 1 A Novel Class of Amphipathic DNA Polymers Inhibits Hepatitis C Virus Infection by Blocking Viral Entry Takuya Matsumura 1 Canada 12:00 Lunch Oral Session VI: Other Viruses and Late Breaker Presentations Celebrity Ballroom EFGH Chairs: Brian Gowen, Ph.D. and Roger Ptak 13:30 38. Comparative Activity of Anti-Enteroviral Agents Against Poliovirus Replication In Vitro; Implications for the End Phase of the Polio Eradication Initiative Armando M De Palma 1 Carbohydrate-Binding Agents (CBAs) Selectively Target the Glycoproteins of the HCV and HIV Envelope to Prevent Vitro and In Vivo Activity of T-705 Against Arenavirus and Bunyavirus Infections Kie-Hoon Jung 1 , Min-Hui Wong 1 QSAR Studies on [(Biphenyloxy)Propyl]Isoxazole Derivatives With Anti-Rhinovirus 2 Activity E. Muratov 1,2 , V. Kuz'min 1,2 , A. Artemenko 2 , I. Volineckaya 2 2 A.V. Bogatsky Physical-Chemical Institute NAS of