key: cord-0031419-002le26o
authors: Sookaromdee, Pathum; Wiwanitkit, Viroj
title: Effectiveness of mRNA Covid-19 vaccine in healthcare workers
date: 2022-05-13
journal: Enferm Infecc Microbiol Clin (Engl Ed)
DOI: 10.1016/j.eimce.2021.08.015
sha: f811302c06bf7efde2b3a135f9c93b8e8a6bb658
doc_id: 31419
cord_uid: 002le26o

nan

We would like to discuss on publication entitled "Effectiveness of the BNT162b2 mRNA Covid-19 vaccine in Spanish healthcare workers." 1 1. Núñez López et al. concluded that "BNT162b2 mRNA COVID-19 vaccine is highly effective in Spanish HCW." 1 We agree that mRNA vaccine might be useful. However, it might be difficult to say that the vaccine is highly effective. Without laboratory investigation on protective antibody titer, the data on incidence of disease might be only indirect clinical evidence. The infection incidence might be associated with many factors including situation of disease epidemic, which is different at different time period. Without an investigation, it is not possible to detect the silent asymptomatic infection among HCW. In a setting the zero COVID-19 case in hospital, the positivity among HCW is still possible. 2 

Effectiveness of the BNT162b2 mRNA Covid-19 vaccine in Spanish healthcare workers

Seroprevalence of hospital staff in a province with zero COVID-19 cases

Pathum Sookaromdee a, * , Viroj Wiwanitkit b a Private Academic Consultant

None.