key: cord-0011609-ckchywc9
authors: Patanè, Luisa; Morotti, Denise; Giunta, Monica Rosaria; Sigismondi, Cristina; Piccoli, Maria Giovanna; Frigerio, Luigi; Mangili, Giovanna; Arosio, Marco; Cornolti, Giorgio
title: Vertical transmission of COVID-19: SARS-CoV-2 RNA on the fetal side of the placenta in pregnancies with COVID-19 positive mothers and neonates at birth
date: 2020-05-18
journal: Am J Obstet Gynecol MFM
DOI: 10.1016/j.ajogmf.2020.100145
sha: 03eeb5115edf80fd1bab0545d7656ea8fe6fbb68
doc_id: 11609
cord_uid: ckchywc9

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Hospital in Bergamo between March 5, 2020 and April 21, 2020 were included in the study.

Maternal and neonatal charts were retrospectively reviewed. Institutional Review Board approved 17 the study and informed consent were obtained from the patients.

All the placentas were collected at birth, and sampled and analyzed at Papa Giovanni XXIII 20 Hospital.

Paraffin-embedded formalin-fixed placentas sections were incubated with hematoxylin and eosin 22 (DAKO) and anti-CD68 antibody (mouse origin , Clone KP1, DAKO) that stains macrophages. 

Case 1: The first neonate was vaginally delivered on March 27, after spontaneous labor of a mother with fever, cough and positive COVID-19 NP at 37.6 weeks of gestation. Neonatal weight was 

CoV-2 (COVID-19)

With COVID-19 Pneumonia JAMA

A case report of neonatal COVID-19 infection in China 131

Detection of SARS-COV-2 in Placental and Fetal Membrane Samples