id	sid	tid	token	lemma	pos
xs55m904d26	1	1	this	this	DET
xs55m904d26	1	2	work	work	NOUN
xs55m904d26	1	3	explores	explore	VERB
xs55m904d26	1	4	the	the	DET
xs55m904d26	1	5	synthesis	synthesis	NOUN
xs55m904d26	1	6	of	of	ADP
xs55m904d26	1	7	two	two	NUM
xs55m904d26	1	8	natural	natural	ADJ
xs55m904d26	1	9	products	product	NOUN
xs55m904d26	1	10	possessing	possess	VERB
xs55m904d26	1	11	unusual	unusual	ADJ
xs55m904d26	1	12	amino	amino	NOUN
xs55m904d26	1	13	acid	acid	NOUN
xs55m904d26	1	14	residues	residue	NOUN
xs55m904d26	1	15	,	,	PUNCT
xs55m904d26	1	16	as	as	ADV
xs55m904d26	1	17	well	well	ADV
xs55m904d26	1	18	as	as	ADP
xs55m904d26	1	19	a	a	DET
xs55m904d26	1	20	bioinspired	bioinspired	ADJ
xs55m904d26	1	21	unnatural	unnatural	ADJ
xs55m904d26	1	22	prolyl	prolyl	NOUN
xs55m904d26	1	23	residue.pseudouridimycin	residue.pseudouridimycin	PROPN
xs55m904d26	1	24	(	(	PUNCT
xs55m904d26	1	25	pum	pum	PROPN
xs55m904d26	1	26	)	)	PUNCT
xs55m904d26	1	27	is	be	AUX
xs55m904d26	1	28	a	a	DET
xs55m904d26	1	29	naturally	naturally	ADV
xs55m904d26	1	30	occurring	occur	VERB
xs55m904d26	1	31	c	c	NOUN
xs55m904d26	1	32	-	-	PUNCT
xs55m904d26	1	33	nucleoside	nucleoside	NOUN
xs55m904d26	1	34	dipeptide	dipeptide	NOUN
xs55m904d26	1	35	antibiotic	antibiotic	ADJ
xs55m904d26	1	36	.	.	PUNCT
xs55m904d26	2	1	pum	pum	PROPN
xs55m904d26	2	2	inhibits	inhibit	VERB
xs55m904d26	2	3	bacterial	bacterial	ADJ
xs55m904d26	2	4	rna	rna	PROPN
xs55m904d26	2	5	polymerase	polymerase	NOUN
xs55m904d26	2	6	(	(	PUNCT
xs55m904d26	2	7	rnap	rnap	NOUN
xs55m904d26	2	8	)	)	PUNCT
xs55m904d26	2	9	in	in	ADP
xs55m904d26	2	10	vitro	vitro	X
xs55m904d26	2	11	at	at	ADP
xs55m904d26	2	12	nanomolar	nanomolar	ADJ
xs55m904d26	2	13	concentrations	concentration	NOUN
xs55m904d26	2	14	while	while	SCONJ
xs55m904d26	2	15	exhibiting	exhibit	VERB
xs55m904d26	2	16	&	&	CCONJ
xs55m904d26	2	17	gt;10	gt;10	SPACE
xs55m904d26	2	18	-	-	ADJ
xs55m904d26	2	19	fold	fold	VERB
xs55m904d26	2	20	selectivity	selectivity	NOUN
xs55m904d26	2	21	over	over	ADP
xs55m904d26	2	22	human	human	ADJ
xs55m904d26	2	23	and	and	CCONJ
xs55m904d26	2	24	viral	viral	ADJ
xs55m904d26	2	25	rnap	rnap	NOUN
xs55m904d26	2	26	.	.	PUNCT
xs55m904d26	3	1	it	it	PRON
xs55m904d26	3	2	also	also	ADV
xs55m904d26	3	3	exhibits	exhibit	VERB
xs55m904d26	3	4	a	a	DET
xs55m904d26	3	5	10	10	NUM
xs55m904d26	3	6	-	-	ADJ
xs55m904d26	3	7	fold	fold	VERB
xs55m904d26	3	8	lower	low	ADJ
xs55m904d26	3	9	rate	rate	NOUN
xs55m904d26	3	10	of	of	ADP
xs55m904d26	3	11	spontaneous	spontaneous	ADJ
xs55m904d26	3	12	resistance	resistance	NOUN
xs55m904d26	3	13	in	in	ADP
xs55m904d26	3	14	s.	s.	PROPN
xs55m904d26	3	15	pyogenes	pyogene	NOUN
xs55m904d26	3	16	rnap	rnap	NOUN
xs55m904d26	3	17	compared	compare	VERB
xs55m904d26	3	18	to	to	ADP
xs55m904d26	3	19	rifampicin	rifampicin	PROPN
xs55m904d26	3	20	(	(	PUNCT
xs55m904d26	3	21	rif	rif	PROPN
xs55m904d26	3	22	)	)	PUNCT
xs55m904d26	3	23	.	.	PUNCT
xs55m904d26	4	1	this	this	DET
xs55m904d26	4	2	natural	natural	ADJ
xs55m904d26	4	3	product	product	NOUN
xs55m904d26	4	4	harbors	harbor	VERB
xs55m904d26	4	5	a	a	DET
xs55m904d26	4	6	dipeptide	dipeptide	NOUN
xs55m904d26	4	7	tail	tail	NOUN
xs55m904d26	4	8	that	that	PRON
xs55m904d26	4	9	consists	consist	VERB
xs55m904d26	4	10	of	of	ADP
xs55m904d26	4	11	n	n	NOUN
xs55m904d26	4	12	-	-	PUNCT
xs55m904d26	4	13	guanidinoglycine	guanidinoglycine	NOUN
xs55m904d26	4	14	and	and	CCONJ
xs55m904d26	4	15	n	n	NOUN
xs55m904d26	4	16	-	-	PUNCT
xs55m904d26	4	17	hydroxyglutamine	hydroxyglutamine	ADJ
xs55m904d26	4	18	(	(	PUNCT
xs55m904d26	4	19	hgln	hgln	PROPN
xs55m904d26	4	20	)	)	PUNCT
xs55m904d26	4	21	residues	residue	NOUN
xs55m904d26	4	22	,	,	PUNCT
xs55m904d26	4	23	as	as	ADV
xs55m904d26	4	24	well	well	ADV
xs55m904d26	4	25	as	as	ADP
xs55m904d26	4	26	a	a	DET
xs55m904d26	4	27	β	β	ADJ
xs55m904d26	4	28	-	-	PUNCT
xs55m904d26	4	29	pseudouridyl	pseudouridyl	ADJ
xs55m904d26	4	30	moiety	moiety	NOUN
xs55m904d26	4	31	.	.	PUNCT
xs55m904d26	5	1	we	we	PRON
xs55m904d26	5	2	report	report	VERB
xs55m904d26	5	3	our	our	PRON
xs55m904d26	5	4	total	total	ADJ
xs55m904d26	5	5	synthesis	synthesis	NOUN
xs55m904d26	5	6	of	of	ADP
xs55m904d26	5	7	pum	pum	PROPN
xs55m904d26	5	8	and	and	CCONJ
xs55m904d26	5	9	the	the	DET
xs55m904d26	5	10	structure	structure	NOUN
xs55m904d26	5	11	-	-	PUNCT
xs55m904d26	5	12	based	base	VERB
xs55m904d26	5	13	design	design	NOUN
xs55m904d26	5	14	of	of	ADP
xs55m904d26	5	15	dipeptidyl	dipeptidyl	NOUN
xs55m904d26	5	16	analogues	analogue	NOUN
xs55m904d26	5	17	.	.	PUNCT
xs55m904d26	6	1	we	we	PRON
xs55m904d26	6	2	also	also	ADV
xs55m904d26	6	3	explore	explore	VERB
xs55m904d26	6	4	conformation	conformation	NOUN
xs55m904d26	6	5	-	-	PUNCT
xs55m904d26	6	6	activity	activity	NOUN
xs55m904d26	6	7	relationships	relationship	NOUN
xs55m904d26	6	8	for	for	ADP
xs55m904d26	6	9	pum	pum	PROPN
xs55m904d26	6	10	via	via	ADP
xs55m904d26	6	11	modifications	modification	NOUN
xs55m904d26	6	12	to	to	ADP
xs55m904d26	6	13	the	the	DET
xs55m904d26	6	14	dipeptide	dipeptide	NOUN
xs55m904d26	6	15	hydroxamate	hydroxamate	NOUN
xs55m904d26	6	16	bond.as	bond.as	NUM
xs55m904d26	6	17	part	part	NOUN
xs55m904d26	6	18	of	of	ADP
xs55m904d26	6	19	our	our	PRON
xs55m904d26	6	20	continued	continue	VERB
xs55m904d26	6	21	interest	interest	NOUN
xs55m904d26	6	22	in	in	ADP
xs55m904d26	6	23	hydroxamate	hydroxamate	NOUN
xs55m904d26	6	24	-	-	PUNCT
xs55m904d26	6	25	containing	contain	VERB
xs55m904d26	6	26	residues	residue	NOUN
xs55m904d26	6	27	,	,	PUNCT
xs55m904d26	6	28	we	we	PRON
xs55m904d26	6	29	devised	devise	VERB
xs55m904d26	6	30	the	the	DET
xs55m904d26	6	31	synthesis	synthesis	NOUN
xs55m904d26	6	32	of	of	ADP
xs55m904d26	6	33	an	an	DET
xs55m904d26	6	34	unnatural	unnatural	ADJ
xs55m904d26	6	35	analogue	analogue	NOUN
xs55m904d26	6	36	of	of	ADP
xs55m904d26	6	37	pipecolic	pipecolic	PROPN
xs55m904d26	6	38	acid	acid	PROPN
xs55m904d26	6	39	(	(	PUNCT
xs55m904d26	6	40	pip	pip	PROPN
xs55m904d26	6	41	)	)	PUNCT
xs55m904d26	6	42	,	,	PUNCT
xs55m904d26	6	43	ε	ε	PROPN
xs55m904d26	6	44	-	-	PUNCT
xs55m904d26	6	45	oxapipicolic	oxapipicolic	PROPN
xs55m904d26	6	46	acid	acid	NOUN
xs55m904d26	6	47	(	(	PUNCT
xs55m904d26	6	48	oxapip	oxapip	NOUN
xs55m904d26	6	49	)	)	PUNCT
xs55m904d26	6	50	.	.	PUNCT
xs55m904d26	7	1	immunosuppressants	immunosuppressant	NOUN
xs55m904d26	7	2	fk506	fk506	PROPN
xs55m904d26	7	3	and	and	CCONJ
xs55m904d26	7	4	rapamycin	rapamycin	NOUN
xs55m904d26	7	5	are	be	AUX
xs55m904d26	7	6	only	only	ADV
xs55m904d26	7	7	biologically	biologically	ADV
xs55m904d26	7	8	active	active	ADJ
xs55m904d26	7	9	when	when	SCONJ
xs55m904d26	7	10	the	the	DET
xs55m904d26	7	11	amide	amide	PROPN
xs55m904d26	7	12	bond	bond	PROPN
xs55m904d26	7	13	preceding	precede	VERB
xs55m904d26	7	14	pip	pip	PROPN
xs55m904d26	7	15	adopts	adopt	VERB
xs55m904d26	7	16	the	the	DET
xs55m904d26	7	17	trans	trans	PROPN
xs55m904d26	7	18	conformation	conformation	NOUN
xs55m904d26	7	19	,	,	PUNCT
xs55m904d26	7	20	highlighting	highlight	VERB
xs55m904d26	7	21	a	a	DET
xs55m904d26	7	22	need	need	NOUN
xs55m904d26	7	23	for	for	ADP
xs55m904d26	7	24	trans	trans	ADJ
xs55m904d26	7	25	-	-	VERB
xs55m904d26	7	26	inducing	inducing	ADJ
xs55m904d26	7	27	pip	pip	PROPN
xs55m904d26	7	28	surrogates	surrogate	NOUN
xs55m904d26	7	29	.	.	PUNCT
xs55m904d26	8	1	utilizing	utilize	VERB
xs55m904d26	8	2	model	model	NOUN
xs55m904d26	8	3	systems	system	NOUN
xs55m904d26	8	4	,	,	PUNCT
xs55m904d26	8	5	we	we	PRON
xs55m904d26	8	6	determined	determine	VERB
xs55m904d26	8	7	that	that	SCONJ
xs55m904d26	8	8	oxapip	oxapip	PROPN
xs55m904d26	8	9	enhanced	enhance	VERB
xs55m904d26	8	10	trans	trans	PROPN
xs55m904d26	8	11	amide	amide	PROPN
xs55m904d26	8	12	population	population	NOUN
xs55m904d26	8	13	in	in	ADP
xs55m904d26	8	14	peptides	peptide	NOUN
xs55m904d26	8	15	,	,	PUNCT
xs55m904d26	8	16	which	which	PRON
xs55m904d26	8	17	we	we	PRON
xs55m904d26	8	18	presumed	presume	VERB
xs55m904d26	8	19	was	be	AUX
xs55m904d26	8	20	due	due	ADJ
xs55m904d26	8	21	to	to	ADP
xs55m904d26	8	22	lone	lone	ADJ
xs55m904d26	8	23	pair	pair	NOUN
xs55m904d26	8	24	-	-	PUNCT
xs55m904d26	8	25	lone	lone	ADJ
xs55m904d26	8	26	pair	pair	NOUN
xs55m904d26	8	27	repulsion	repulsion	NOUN
xs55m904d26	8	28	between	between	ADP
xs55m904d26	8	29	the	the	DET
xs55m904d26	8	30	amide	amide	PROPN
xs55m904d26	8	31	carbonyl	carbonyl	PROPN
xs55m904d26	8	32	and	and	CCONJ
xs55m904d26	8	33	the	the	DET
xs55m904d26	8	34	oxapip	oxapip	PROPN
xs55m904d26	8	35	ε	ε	PROPN
xs55m904d26	8	36	oxygen	oxygen	PROPN
xs55m904d26	8	37	.	.	PUNCT
xs55m904d26	9	1	we	we	PRON
xs55m904d26	9	2	also	also	ADV
xs55m904d26	9	3	pursued	pursue	VERB
xs55m904d26	9	4	the	the	DET
xs55m904d26	9	5	total	total	ADJ
xs55m904d26	9	6	synthesis	synthesis	NOUN
xs55m904d26	9	7	of	of	ADP
xs55m904d26	9	8	eleganine	eleganine	PROPN
xs55m904d26	9	9	a	a	PROPN
xs55m904d26	9	10	,	,	PUNCT
xs55m904d26	9	11	a	a	DET
xs55m904d26	9	12	complex	complex	ADJ
xs55m904d26	9	13	indole	indole	ADJ
xs55m904d26	9	14	alkaloid	alkaloid	ADJ
xs55m904d26	9	15	natural	natural	ADJ
xs55m904d26	9	16	product	product	NOUN
xs55m904d26	9	17	capable	capable	ADJ
xs55m904d26	9	18	of	of	ADP
xs55m904d26	9	19	inducing	induce	VERB
xs55m904d26	9	20	apoptosis	apoptosis	NOUN
xs55m904d26	9	21	in	in	ADP
xs55m904d26	9	22	huh-7	huh-7	PUNCT
xs55m904d26	9	23	cancer	cancer	NOUN
xs55m904d26	9	24	cells	cell	NOUN
xs55m904d26	9	25	.	.	PUNCT
xs55m904d26	10	1	this	this	DET
xs55m904d26	10	2	molecule	molecule	NOUN
xs55m904d26	10	3	possesses	possess	VERB
xs55m904d26	10	4	an	an	DET
xs55m904d26	10	5	unusual	unusual	ADJ
xs55m904d26	10	6	ethylideneproline	ethylideneproline	ADJ
xs55m904d26	10	7	core	core	NOUN
xs55m904d26	10	8	with	with	ADP
xs55m904d26	10	9	e	e	PROPN
xs55m904d26	10	10	alkene	alkene	NOUN
xs55m904d26	10	11	geometry	geometry	NOUN
xs55m904d26	10	12	.	.	PUNCT
xs55m904d26	11	1	we	we	PRON
xs55m904d26	11	2	devised	devise	VERB
xs55m904d26	11	3	a	a	DET
xs55m904d26	11	4	nickel	nickel	NOUN
xs55m904d26	11	5	-	-	PUNCT
xs55m904d26	11	6	catalyzed	catalyze	VERB
xs55m904d26	11	7	route	route	NOUN
xs55m904d26	11	8	to	to	ADP
xs55m904d26	11	9	this	this	DET
xs55m904d26	11	10	proline	proline	NOUN
xs55m904d26	11	11	analogue	analogue	NOUN
xs55m904d26	11	12	that	that	PRON
xs55m904d26	11	13	was	be	AUX
xs55m904d26	11	14	highly	highly	ADV
xs55m904d26	11	15	selective	selective	ADJ
xs55m904d26	11	16	for	for	ADP
xs55m904d26	11	17	the	the	DET
xs55m904d26	11	18	desired	desire	VERB
xs55m904d26	11	19	alkene	alkene	NOUN
xs55m904d26	11	20	geometry	geometry	NOUN
xs55m904d26	11	21	,	,	PUNCT
xs55m904d26	11	22	while	while	SCONJ
xs55m904d26	11	23	also	also	ADV
xs55m904d26	11	24	installing	instal	VERB
xs55m904d26	11	25	the	the	DET
xs55m904d26	11	26	necessary	necessary	ADJ
xs55m904d26	11	27	trans	trans	PROPN
xs55m904d26	11	28	stereochemistry	stereochemistry	NOUN
xs55m904d26	11	29	for	for	ADP
xs55m904d26	11	30	the	the	DET
xs55m904d26	11	31	c2,c3	c2,c3	PROPN
xs55m904d26	11	32	ring	ring	NOUN
xs55m904d26	11	33	substituents	substituent	NOUN
xs55m904d26	11	34	.	.	PUNCT
xs55m904d26	12	1	we	we	PRON
xs55m904d26	12	2	successfully	successfully	ADV
xs55m904d26	12	3	employed	employ	VERB
xs55m904d26	12	4	larock	larock	ADJ
xs55m904d26	12	5	heteroannulation	heteroannulation	NOUN
xs55m904d26	12	6	to	to	PART
xs55m904d26	12	7	link	link	VERB
xs55m904d26	12	8	the	the	DET
xs55m904d26	12	9	ethylideneproline	ethylideneproline	ADJ
xs55m904d26	12	10	ring	ring	NOUN
xs55m904d26	12	11	to	to	ADP
xs55m904d26	12	12	a	a	DET
xs55m904d26	12	13	substituted	substituted	ADJ
xs55m904d26	12	14	indole	indole	NOUN
xs55m904d26	12	15	.	.	PUNCT
xs55m904d26	13	1	unfortunately	unfortunately	ADV
xs55m904d26	13	2	,	,	PUNCT
xs55m904d26	13	3	attempts	attempt	VERB
xs55m904d26	13	4	to	to	PART
xs55m904d26	13	5	form	form	VERB
xs55m904d26	13	6	the	the	DET
xs55m904d26	13	7	final	final	ADJ
xs55m904d26	13	8	intramolecular	intramolecular	ADJ
xs55m904d26	13	9	hemiaminal	hemiaminal	ADJ
xs55m904d26	13	10	ether	ether	NOUN
xs55m904d26	13	11	bond	bond	NOUN
xs55m904d26	13	12	of	of	ADP
xs55m904d26	13	13	eleganine	eleganine	PROPN
xs55m904d26	13	14	a	a	PRON
xs55m904d26	13	15	were	be	AUX
xs55m904d26	13	16	unsuccessful	unsuccessful	ADJ
xs55m904d26	13	17	,	,	PUNCT
xs55m904d26	13	18	instead	instead	ADV
xs55m904d26	13	19	affording	afford	VERB
xs55m904d26	13	20	us	we	PRON
xs55m904d26	13	21	an	an	DET
xs55m904d26	13	22	enamine	enamine	NOUN
xs55m904d26	13	23	dimer	dimer	NOUN
xs55m904d26	13	24	product	product	NOUN
xs55m904d26	13	25	.	.	PUNCT