id sid tid token lemma pos xd07gq7176p 1 1 cardiovascular cardiovascular ADJ xd07gq7176p 1 2 diseases disease NOUN xd07gq7176p 1 3 ( ( PUNCT xd07gq7176p 1 4 cvd cvd PROPN xd07gq7176p 1 5 ) ) PUNCT xd07gq7176p 1 6 have have AUX xd07gq7176p 1 7 been be AUX xd07gq7176p 1 8 the the DET xd07gq7176p 1 9 leading lead VERB xd07gq7176p 1 10 cause cause NOUN xd07gq7176p 1 11 of of ADP xd07gq7176p 1 12 death death NOUN xd07gq7176p 1 13 in in ADP xd07gq7176p 1 14 the the DET xd07gq7176p 1 15 developed develop VERB xd07gq7176p 1 16 world world NOUN xd07gq7176p 1 17 for for ADP xd07gq7176p 1 18 nearly nearly ADV xd07gq7176p 1 19 100 100 NUM xd07gq7176p 1 20 years year NOUN xd07gq7176p 1 21 , , PUNCT xd07gq7176p 1 22 responsible responsible ADJ xd07gq7176p 1 23 for for ADP xd07gq7176p 1 24 nearly nearly ADV xd07gq7176p 1 25 18 18 NUM xd07gq7176p 1 26 million million NUM xd07gq7176p 1 27 deaths death NOUN xd07gq7176p 1 28 yearly yearly ADV xd07gq7176p 1 29 , , PUNCT xd07gq7176p 1 30 more more ADJ xd07gq7176p 1 31 deaths death NOUN xd07gq7176p 1 32 than than ADP xd07gq7176p 1 33 all all DET xd07gq7176p 1 34 forms form NOUN xd07gq7176p 1 35 of of ADP xd07gq7176p 1 36 cancer cancer NOUN xd07gq7176p 1 37 combined combine VERB xd07gq7176p 1 38 . . PUNCT xd07gq7176p 2 1 the the DET xd07gq7176p 2 2 majority majority NOUN xd07gq7176p 2 3 of of ADP xd07gq7176p 2 4 cvd cvd PROPN xd07gq7176p 2 5 related relate VERB xd07gq7176p 2 6 deaths death NOUN xd07gq7176p 2 7 are be AUX xd07gq7176p 2 8 due due ADJ xd07gq7176p 2 9 to to ADP xd07gq7176p 2 10 myocardial myocardial ADJ xd07gq7176p 2 11 infarction infarction NOUN xd07gq7176p 2 12 ( ( PUNCT xd07gq7176p 2 13 mi mi PROPN xd07gq7176p 2 14 ) ) PUNCT xd07gq7176p 2 15 . . PUNCT xd07gq7176p 3 1 additionally additionally ADV xd07gq7176p 3 2 , , PUNCT xd07gq7176p 3 3 the the DET xd07gq7176p 3 4 only only ADJ xd07gq7176p 3 5 viable viable ADJ xd07gq7176p 3 6 long long ADJ xd07gq7176p 3 7 - - PUNCT xd07gq7176p 3 8 term term NOUN xd07gq7176p 3 9 solution solution NOUN xd07gq7176p 3 10 for for ADP xd07gq7176p 3 11 undiagnosed undiagnosed ADJ xd07gq7176p 3 12 mis mis PROPN xd07gq7176p 3 13 and and CCONJ xd07gq7176p 3 14 the the DET xd07gq7176p 3 15 remaining remain VERB xd07gq7176p 3 16 cvds cvds PROPN xd07gq7176p 3 17 is be AUX xd07gq7176p 3 18 heart heart NOUN xd07gq7176p 3 19 transplant transplant NOUN xd07gq7176p 3 20 , , PUNCT xd07gq7176p 3 21 in in ADP xd07gq7176p 3 22 which which PRON xd07gq7176p 3 23 nearly nearly ADV xd07gq7176p 3 24 70 70 NUM xd07gq7176p 3 25 % % NOUN xd07gq7176p 3 26 of of ADP xd07gq7176p 3 27 potential potential ADJ xd07gq7176p 3 28 donor donor NOUN xd07gq7176p 3 29 organs organ NOUN xd07gq7176p 3 30 are be AUX xd07gq7176p 3 31 deemed deem VERB xd07gq7176p 3 32 unusable unusable ADJ xd07gq7176p 3 33 . . PUNCT xd07gq7176p 4 1 the the DET xd07gq7176p 4 2 major major ADJ xd07gq7176p 4 3 mechanism mechanism NOUN xd07gq7176p 4 4 of of ADP xd07gq7176p 4 5 damage damage NOUN xd07gq7176p 4 6 for for ADP xd07gq7176p 4 7 both both DET xd07gq7176p 4 8 mi mi NOUN xd07gq7176p 4 9 as as ADV xd07gq7176p 4 10 well well ADV xd07gq7176p 4 11 as as ADP xd07gq7176p 4 12 that that PRON xd07gq7176p 4 13 which which PRON xd07gq7176p 4 14 occurs occur VERB xd07gq7176p 4 15 during during ADP xd07gq7176p 4 16 organ organ NOUN xd07gq7176p 4 17 procurement procurement NOUN xd07gq7176p 4 18 and and CCONJ xd07gq7176p 4 19 transplantation transplantation NOUN xd07gq7176p 4 20 is be AUX xd07gq7176p 4 21 ischemic ischemic ADJ xd07gq7176p 4 22 / / SYM xd07gq7176p 4 23 reperfusion reperfusion NOUN xd07gq7176p 4 24 injury injury NOUN xd07gq7176p 4 25 ( ( PUNCT xd07gq7176p 4 26 i i NOUN xd07gq7176p 4 27 / / SYM xd07gq7176p 4 28 r r NOUN xd07gq7176p 4 29 ) ) PUNCT xd07gq7176p 4 30 . . PUNCT xd07gq7176p 5 1 due due ADP xd07gq7176p 5 2 to to ADP xd07gq7176p 5 3 an an DET xd07gq7176p 5 4 extreme extreme ADJ xd07gq7176p 5 5 limit limit NOUN xd07gq7176p 5 6 on on ADP xd07gq7176p 5 7 viable viable ADJ xd07gq7176p 5 8 human human ADJ xd07gq7176p 5 9 hearts heart NOUN xd07gq7176p 5 10 available available ADJ xd07gq7176p 5 11 for for ADP xd07gq7176p 5 12 transplant transplant NOUN xd07gq7176p 5 13 , , PUNCT xd07gq7176p 5 14 let let VERB xd07gq7176p 5 15 alone alone ADJ xd07gq7176p 5 16 research research NOUN xd07gq7176p 5 17 , , PUNCT xd07gq7176p 5 18 the the DET xd07gq7176p 5 19 use use NOUN xd07gq7176p 5 20 of of ADP xd07gq7176p 5 21 animal animal NOUN xd07gq7176p 5 22 models model NOUN xd07gq7176p 5 23 has have AUX xd07gq7176p 5 24 become become VERB xd07gq7176p 5 25 a a DET xd07gq7176p 5 26 common common ADJ xd07gq7176p 5 27 alternative alternative NOUN xd07gq7176p 5 28 for for ADP xd07gq7176p 5 29 cvd cvd PROPN xd07gq7176p 5 30 study study PROPN xd07gq7176p 5 31 . . PUNCT xd07gq7176p 6 1 unfortunately unfortunately ADV xd07gq7176p 6 2 , , PUNCT xd07gq7176p 6 3 due due ADP xd07gq7176p 6 4 to to ADP xd07gq7176p 6 5 differences difference NOUN xd07gq7176p 6 6 in in ADP xd07gq7176p 6 7 human human ADJ xd07gq7176p 6 8 and and CCONJ xd07gq7176p 6 9 animal animal NOUN xd07gq7176p 6 10 physiology physiology NOUN xd07gq7176p 6 11 and and CCONJ xd07gq7176p 6 12 pathology pathology NOUN xd07gq7176p 6 13 , , PUNCT xd07gq7176p 6 14 results result NOUN xd07gq7176p 6 15 from from ADP xd07gq7176p 6 16 such such ADJ xd07gq7176p 6 17 studies study NOUN xd07gq7176p 6 18 are be AUX xd07gq7176p 6 19 often often ADV xd07gq7176p 6 20 inconclusive inconclusive ADJ xd07gq7176p 6 21 or or CCONJ xd07gq7176p 6 22 contradictive contradictive ADJ xd07gq7176p 6 23 to to ADP xd07gq7176p 6 24 one one NUM xd07gq7176p 6 25 another.in another.in NUM xd07gq7176p 6 26 recent recent ADJ xd07gq7176p 6 27 decades decade NOUN xd07gq7176p 6 28 , , PUNCT xd07gq7176p 6 29 tissue tissue NOUN xd07gq7176p 6 30 engineering engineering NOUN xd07gq7176p 6 31 has have AUX xd07gq7176p 6 32 developed develop VERB xd07gq7176p 6 33 model model NOUN xd07gq7176p 6 34 tissues tissue NOUN xd07gq7176p 6 35 utilizing utilize VERB xd07gq7176p 6 36 human human ADJ xd07gq7176p 6 37 derived derive VERB xd07gq7176p 6 38 cells cell NOUN xd07gq7176p 6 39 to to PART xd07gq7176p 6 40 better well ADV xd07gq7176p 6 41 mimic mimic VERB xd07gq7176p 6 42 human human ADJ xd07gq7176p 6 43 physiology physiology NOUN xd07gq7176p 6 44 in in ADP xd07gq7176p 6 45 vitro vitro X xd07gq7176p 6 46 . . PUNCT xd07gq7176p 7 1 this this PRON xd07gq7176p 7 2 reduces reduce VERB xd07gq7176p 7 3 species specie NOUN xd07gq7176p 7 4 to to ADP xd07gq7176p 7 5 species species NOUN xd07gq7176p 7 6 variability variability NOUN xd07gq7176p 7 7 as as ADV xd07gq7176p 7 8 well well ADV xd07gq7176p 7 9 as as ADP xd07gq7176p 7 10 ethical ethical ADJ xd07gq7176p 7 11 concerns concern NOUN xd07gq7176p 7 12 regarding regard VERB xd07gq7176p 7 13 usage usage NOUN xd07gq7176p 7 14 of of ADP xd07gq7176p 7 15 clinically clinically ADV xd07gq7176p 7 16 precious precious ADJ xd07gq7176p 7 17 human human ADJ xd07gq7176p 7 18 organs organ NOUN xd07gq7176p 7 19 . . PUNCT xd07gq7176p 8 1 several several ADJ xd07gq7176p 8 2 studies study NOUN xd07gq7176p 8 3 have have AUX xd07gq7176p 8 4 utilized utilize VERB xd07gq7176p 8 5 tissue tissue NOUN xd07gq7176p 8 6 engineered engineer VERB xd07gq7176p 8 7 methods method NOUN xd07gq7176p 8 8 for for ADP xd07gq7176p 8 9 studying study VERB xd07gq7176p 8 10 human human ADJ xd07gq7176p 8 11 myocardium myocardium NOUN xd07gq7176p 8 12 , , PUNCT xd07gq7176p 8 13 however however ADV xd07gq7176p 8 14 they they PRON xd07gq7176p 8 15 have have AUX xd07gq7176p 8 16 been be AUX xd07gq7176p 8 17 restricted restrict VERB xd07gq7176p 8 18 to to ADP xd07gq7176p 8 19 specific specific ADJ xd07gq7176p 8 20 characterization characterization NOUN xd07gq7176p 8 21 and/or and/or CCONJ xd07gq7176p 8 22 pharmaceutical pharmaceutical NOUN xd07gq7176p 8 23 screening screening NOUN xd07gq7176p 8 24 rather rather ADV xd07gq7176p 8 25 than than ADP xd07gq7176p 8 26 recapitulating recapitulate VERB xd07gq7176p 8 27 a a DET xd07gq7176p 8 28 physiologically physiologically ADV xd07gq7176p 8 29 relevant relevant ADJ xd07gq7176p 8 30 human human ADJ xd07gq7176p 8 31 heart heart NOUN xd07gq7176p 8 32 tissue tissue NOUN xd07gq7176p 8 33 model model NOUN xd07gq7176p 8 34 . . PUNCT xd07gq7176p 9 1 it it PRON xd07gq7176p 9 2 is be AUX xd07gq7176p 9 3 imperative imperative ADJ xd07gq7176p 9 4 that that SCONJ xd07gq7176p 9 5 a a DET xd07gq7176p 9 6 physiologically physiologically ADV xd07gq7176p 9 7 relevant relevant ADJ xd07gq7176p 9 8 model model NOUN xd07gq7176p 9 9 is be AUX xd07gq7176p 9 10 developed develop VERB xd07gq7176p 9 11 to to PART xd07gq7176p 9 12 better well ADV xd07gq7176p 9 13 diagnose diagnose VERB xd07gq7176p 9 14 and and CCONJ xd07gq7176p 9 15 treat treat VERB xd07gq7176p 9 16 cvd cvd PROPN xd07gq7176p 9 17 , , PUNCT xd07gq7176p 9 18 specifically specifically ADV xd07gq7176p 9 19 mi mi NOUN xd07gq7176p 9 20 and and CCONJ xd07gq7176p 9 21 heart heart NOUN xd07gq7176p 9 22 transplant transplant NOUN xd07gq7176p 9 23 , , PUNCT xd07gq7176p 9 24 as as ADP xd07gq7176p 9 25 being be AUX xd07gq7176p 9 26 able able ADJ xd07gq7176p 9 27 to to PART xd07gq7176p 9 28 accurately accurately ADV xd07gq7176p 9 29 identify identify VERB xd07gq7176p 9 30 and and CCONJ xd07gq7176p 9 31 understand understand VERB xd07gq7176p 9 32 the the DET xd07gq7176p 9 33 underlying underlying ADJ xd07gq7176p 9 34 mechanisms mechanism NOUN xd07gq7176p 9 35 of of ADP xd07gq7176p 9 36 i i PRON xd07gq7176p 9 37 / / SYM xd07gq7176p 9 38 r r NOUN xd07gq7176p 9 39 in in ADP xd07gq7176p 9 40 human human ADJ xd07gq7176p 9 41 physiology physiology NOUN xd07gq7176p 9 42 is be AUX xd07gq7176p 9 43 crucial crucial ADJ xd07gq7176p 9 44 for for ADP xd07gq7176p 9 45 cvd cvd PROPN xd07gq7176p 9 46 treatment treatment NOUN xd07gq7176p 9 47 and and CCONJ xd07gq7176p 9 48 prevention.the prevention.the DET xd07gq7176p 9 49 main main ADJ xd07gq7176p 9 50 goal goal NOUN xd07gq7176p 9 51 of of ADP xd07gq7176p 9 52 this this DET xd07gq7176p 9 53 dissertation dissertation NOUN xd07gq7176p 9 54 was be AUX xd07gq7176p 9 55 to to PART xd07gq7176p 9 56 develop develop VERB xd07gq7176p 9 57 a a DET xd07gq7176p 9 58 high high ADJ xd07gq7176p 9 59 throughput throughput NOUN xd07gq7176p 9 60 physiologically physiologically ADV xd07gq7176p 9 61 relevant relevant ADJ xd07gq7176p 9 62 human human ADJ xd07gq7176p 9 63 derived derive VERB xd07gq7176p 9 64 myocardium myocardium NOUN xd07gq7176p 9 65 tissue tissue NOUN xd07gq7176p 9 66 model model NOUN xd07gq7176p 9 67 to to PART xd07gq7176p 9 68 investigate investigate VERB xd07gq7176p 9 69 novel novel ADJ xd07gq7176p 9 70 diagnosis diagnosis NOUN xd07gq7176p 9 71 and and CCONJ xd07gq7176p 9 72 treatment treatment NOUN xd07gq7176p 9 73 methods method NOUN xd07gq7176p 9 74 of of ADP xd07gq7176p 9 75 i i PRON xd07gq7176p 9 76 / / SYM xd07gq7176p 9 77 r r NOUN xd07gq7176p 9 78 in in ADP xd07gq7176p 9 79 both both CCONJ xd07gq7176p 9 80 mi mi NOUN xd07gq7176p 9 81 and and CCONJ xd07gq7176p 9 82 heart heart NOUN xd07gq7176p 9 83 transplantation transplantation NOUN xd07gq7176p 9 84 . . PUNCT xd07gq7176p 10 1 towards towards ADP xd07gq7176p 10 2 this this DET xd07gq7176p 10 3 goal goal NOUN xd07gq7176p 10 4 , , PUNCT xd07gq7176p 10 5 we we PRON xd07gq7176p 10 6 first first ADV xd07gq7176p 10 7 developed develop VERB xd07gq7176p 10 8 a a DET xd07gq7176p 10 9 microfluidic microfluidic ADJ xd07gq7176p 10 10 human human ADJ xd07gq7176p 10 11 heart heart NOUN xd07gq7176p 10 12 anoxia anoxia NOUN xd07gq7176p 10 13 and and CCONJ xd07gq7176p 10 14 reperfusion reperfusion NOUN xd07gq7176p 10 15 tissue tissue NOUN xd07gq7176p 10 16 ( ( PUNCT xd07gq7176p 10 17 heart heart NOUN xd07gq7176p 10 18 ) ) PUNCT xd07gq7176p 10 19 model model NOUN xd07gq7176p 10 20 using use VERB xd07gq7176p 10 21 human human ADJ xd07gq7176p 10 22 induced induce VERB xd07gq7176p 10 23 pluripotent pluripotent ADJ xd07gq7176p 10 24 stem stem NOUN xd07gq7176p 10 25 cell cell NOUN xd07gq7176p 10 26 derived derive VERB xd07gq7176p 10 27 cardiomyocytes cardiomyocyte NOUN xd07gq7176p 10 28 ( ( PUNCT xd07gq7176p 10 29 icms icms NOUN xd07gq7176p 10 30 ) ) PUNCT xd07gq7176p 10 31 and and CCONJ xd07gq7176p 10 32 endothelial endothelial ADJ xd07gq7176p 10 33 cells cell NOUN xd07gq7176p 10 34 ( ( PUNCT xd07gq7176p 10 35 iecs iecs PROPN xd07gq7176p 10 36 ) ) PUNCT xd07gq7176p 10 37 and and CCONJ xd07gq7176p 10 38 observed observe VERB xd07gq7176p 10 39 that that SCONJ xd07gq7176p 10 40 cells cell NOUN xd07gq7176p 10 41 seeded seed VERB xd07gq7176p 10 42 in in ADP xd07gq7176p 10 43 the the DET xd07gq7176p 10 44 heart heart NOUN xd07gq7176p 10 45 retained retain VERB xd07gq7176p 10 46 their their PRON xd07gq7176p 10 47 canonical canonical ADJ xd07gq7176p 10 48 cell cell NOUN xd07gq7176p 10 49 specific specific ADJ xd07gq7176p 10 50 markers marker NOUN xd07gq7176p 10 51 and and CCONJ xd07gq7176p 10 52 functionality functionality NOUN xd07gq7176p 10 53 and and CCONJ xd07gq7176p 10 54 were be AUX xd07gq7176p 10 55 able able ADJ xd07gq7176p 10 56 to to PART xd07gq7176p 10 57 survive survive VERB xd07gq7176p 10 58 within within ADP xd07gq7176p 10 59 the the DET xd07gq7176p 10 60 device device NOUN xd07gq7176p 10 61 for for ADP xd07gq7176p 10 62 up up ADP xd07gq7176p 10 63 to to PART xd07gq7176p 10 64 7 7 NUM xd07gq7176p 10 65 days day NOUN xd07gq7176p 10 66 under under ADP xd07gq7176p 10 67 flow flow NOUN xd07gq7176p 10 68 giving give VERB xd07gq7176p 10 69 physiological physiological ADJ xd07gq7176p 10 70 wall wall NOUN xd07gq7176p 10 71 shear shear PROPN xd07gq7176p 10 72 stresses stress NOUN xd07gq7176p 10 73 . . PUNCT xd07gq7176p 11 1 we we PRON xd07gq7176p 11 2 then then ADV xd07gq7176p 11 3 utilized utilize VERB xd07gq7176p 11 4 the the DET xd07gq7176p 11 5 heart heart NOUN xd07gq7176p 11 6 to to PART xd07gq7176p 11 7 validate validate VERB xd07gq7176p 11 8 the the DET xd07gq7176p 11 9 therapeutic therapeutic ADJ xd07gq7176p 11 10 potential potential NOUN xd07gq7176p 11 11 of of ADP xd07gq7176p 11 12 adipose adipose NOUN xd07gq7176p 11 13 derived derive VERB xd07gq7176p 11 14 mesenchymal mesenchymal NOUN xd07gq7176p 11 15 stem stem NOUN xd07gq7176p 11 16 cell cell NOUN xd07gq7176p 11 17 ( ( PUNCT xd07gq7176p 11 18 asc asc PROPN xd07gq7176p 11 19 ) ) PUNCT xd07gq7176p 11 20 secretome secretome PROPN xd07gq7176p 11 21 ( ( PUNCT xd07gq7176p 11 22 asc asc PROPN xd07gq7176p 11 23 - - PUNCT xd07gq7176p 11 24 s s NUM xd07gq7176p 11 25 ) ) PUNCT xd07gq7176p 11 26 in in ADP xd07gq7176p 11 27 an an DET xd07gq7176p 11 28 organ organ NOUN xd07gq7176p 11 29 transplant transplant NOUN xd07gq7176p 11 30 scenario scenario NOUN xd07gq7176p 11 31 . . PUNCT xd07gq7176p 12 1 we we PRON xd07gq7176p 12 2 showed show VERB xd07gq7176p 12 3 that that SCONJ xd07gq7176p 12 4 the the DET xd07gq7176p 12 5 detrimental detrimental ADJ xd07gq7176p 12 6 effect effect NOUN xd07gq7176p 12 7 of of ADP xd07gq7176p 12 8 cardioplegic cardioplegic ADJ xd07gq7176p 12 9 solution solution NOUN xd07gq7176p 12 10 was be AUX xd07gq7176p 12 11 mainly mainly ADV xd07gq7176p 12 12 limited limited ADJ xd07gq7176p 12 13 to to ADP xd07gq7176p 12 14 icms icms NOUN xd07gq7176p 12 15 , , PUNCT xd07gq7176p 12 16 and and CCONJ xd07gq7176p 12 17 the the DET xd07gq7176p 12 18 inclusion inclusion NOUN xd07gq7176p 12 19 of of ADP xd07gq7176p 12 20 asc asc PROPN xd07gq7176p 12 21 - - PUNCT xd07gq7176p 12 22 s s PROPN xd07gq7176p 12 23 was be AUX xd07gq7176p 12 24 able able ADJ xd07gq7176p 12 25 to to PART xd07gq7176p 12 26 ameliorate ameliorate VERB xd07gq7176p 12 27 this this PRON xd07gq7176p 12 28 via via ADP xd07gq7176p 12 29 the the DET xd07gq7176p 12 30 oxidative oxidative ADJ xd07gq7176p 12 31 stress stress NOUN xd07gq7176p 12 32 pathway pathway NOUN xd07gq7176p 12 33 . . PUNCT xd07gq7176p 13 1 finally finally ADV xd07gq7176p 13 2 , , PUNCT xd07gq7176p 13 3 we we PRON xd07gq7176p 13 4 developed develop VERB xd07gq7176p 13 5 an an DET xd07gq7176p 13 6 in in ADP xd07gq7176p 13 7 vitro vitro X xd07gq7176p 13 8 mi mi PROPN xd07gq7176p 13 9 model model NOUN xd07gq7176p 13 10 for for ADP xd07gq7176p 13 11 the the DET xd07gq7176p 13 12 heart heart NOUN xd07gq7176p 13 13 and and CCONJ xd07gq7176p 13 14 compared compare VERB xd07gq7176p 13 15 mirna mirna ADJ xd07gq7176p 13 16 expression expression NOUN xd07gq7176p 13 17 to to ADP xd07gq7176p 13 18 mi mi PROPN xd07gq7176p 13 19 patients patient NOUN xd07gq7176p 13 20 using use VERB xd07gq7176p 13 21 a a DET xd07gq7176p 13 22 near near ADJ xd07gq7176p 13 23 real real ADJ xd07gq7176p 13 24 - - PUNCT xd07gq7176p 13 25 time time NOUN xd07gq7176p 13 26 mirna mirna PROPN xd07gq7176p 13 27 concentration concentration NOUN xd07gq7176p 13 28 sensor sensor NOUN xd07gq7176p 13 29 , , PUNCT xd07gq7176p 13 30 and and CCONJ xd07gq7176p 13 31 observed observe VERB xd07gq7176p 13 32 that that SCONJ xd07gq7176p 13 33 the the DET xd07gq7176p 13 34 heart heart NOUN xd07gq7176p 13 35 was be AUX xd07gq7176p 13 36 able able ADJ xd07gq7176p 13 37 to to PART xd07gq7176p 13 38 closely closely ADV xd07gq7176p 13 39 mimic mimic VERB xd07gq7176p 13 40 clinical clinical ADJ xd07gq7176p 13 41 mirna mirna PROPN xd07gq7176p 13 42 expression expression NOUN xd07gq7176p 13 43 through through ADP xd07gq7176p 13 44 both both CCONJ xd07gq7176p 13 45 the the DET xd07gq7176p 13 46 ischemic ischemic NOUN xd07gq7176p 13 47 and and CCONJ xd07gq7176p 13 48 reperfusion reperfusion NOUN xd07gq7176p 13 49 stages stage NOUN xd07gq7176p 13 50 of of ADP xd07gq7176p 13 51 mi mi PROPN xd07gq7176p 13 52 . . PUNCT xd07gq7176p 14 1 the the DET xd07gq7176p 14 2 novel novel ADJ xd07gq7176p 14 3 heart heart NOUN xd07gq7176p 14 4 provides provide VERB xd07gq7176p 14 5 researchers researcher NOUN xd07gq7176p 14 6 with with ADP xd07gq7176p 14 7 a a DET xd07gq7176p 14 8 modular modular ADJ xd07gq7176p 14 9 and and CCONJ xd07gq7176p 14 10 physiologically physiologically ADV xd07gq7176p 14 11 relevant relevant ADJ xd07gq7176p 14 12 in in ADP xd07gq7176p 14 13 vitro vitro X xd07gq7176p 14 14 tool tool NOUN xd07gq7176p 14 15 for for ADP xd07gq7176p 14 16 the the DET xd07gq7176p 14 17 development development NOUN xd07gq7176p 14 18 of of ADP xd07gq7176p 14 19 novel novel ADJ xd07gq7176p 14 20 diagnostic diagnostic ADJ xd07gq7176p 14 21 and and CCONJ xd07gq7176p 14 22 therapeutic therapeutic ADJ xd07gq7176p 14 23 approaches approach NOUN xd07gq7176p 14 24 to to ADP xd07gq7176p 14 25 cvd cvd PROPN xd07gq7176p 14 26 . . PUNCT