id sid tid token lemma pos xd07gq70365 1 1 an an DET xd07gq70365 1 2 epithelium epithelium NOUN xd07gq70365 1 3 is be AUX xd07gq70365 1 4 a a DET xd07gq70365 1 5 sheet sheet NOUN xd07gq70365 1 6 of of ADP xd07gq70365 1 7 constantly constantly ADV xd07gq70365 1 8 growing grow VERB xd07gq70365 1 9 cells cell NOUN xd07gq70365 1 10 that that PRON xd07gq70365 1 11 strongly strongly ADV xd07gq70365 1 12 adhere adhere VERB xd07gq70365 1 13 to to ADP xd07gq70365 1 14 their their PRON xd07gq70365 1 15 neighbors neighbor NOUN xd07gq70365 1 16 . . PUNCT xd07gq70365 2 1 studying study VERB xd07gq70365 2 2 mechanisms mechanism NOUN xd07gq70365 2 3 that that PRON xd07gq70365 2 4 regulate regulate VERB xd07gq70365 2 5 the the DET xd07gq70365 2 6 growth growth NOUN xd07gq70365 2 7 of of ADP xd07gq70365 2 8 epithelium epithelium NOUN xd07gq70365 2 9 is be AUX xd07gq70365 2 10 important important ADJ xd07gq70365 2 11 for for ADP xd07gq70365 2 12 both both DET xd07gq70365 2 13 understanding understanding NOUN xd07gq70365 2 14 of of ADP xd07gq70365 2 15 development development NOUN xd07gq70365 2 16 in in ADP xd07gq70365 2 17 general general ADJ xd07gq70365 2 18 and and CCONJ xd07gq70365 2 19 finding find VERB xd07gq70365 2 20 solutions solution NOUN xd07gq70365 2 21 for for ADP xd07gq70365 2 22 diseases disease NOUN xd07gq70365 2 23 . . PUNCT xd07gq70365 3 1 the the DET xd07gq70365 3 2 regulation regulation NOUN xd07gq70365 3 3 of of ADP xd07gq70365 3 4 cell cell NOUN xd07gq70365 3 5 growth growth NOUN xd07gq70365 3 6 and and CCONJ xd07gq70365 3 7 division division NOUN xd07gq70365 3 8 is be AUX xd07gq70365 3 9 one one NUM xd07gq70365 3 10 of of ADP xd07gq70365 3 11 the the DET xd07gq70365 3 12 key key ADJ xd07gq70365 3 13 mechanisms mechanism NOUN xd07gq70365 3 14 that that PRON xd07gq70365 3 15 ensure ensure VERB xd07gq70365 3 16 proper proper ADJ xd07gq70365 3 17 development development NOUN xd07gq70365 3 18 of of ADP xd07gq70365 3 19 living live VERB xd07gq70365 3 20 organisms organism NOUN xd07gq70365 3 21 . . PUNCT xd07gq70365 4 1 compromised compromise VERB xd07gq70365 4 2 regulation regulation NOUN xd07gq70365 4 3 of of ADP xd07gq70365 4 4 proliferation proliferation NOUN xd07gq70365 4 5 could could AUX xd07gq70365 4 6 lead lead VERB xd07gq70365 4 7 to to ADP xd07gq70365 4 8 cancer cancer NOUN xd07gq70365 4 9 , , PUNCT xd07gq70365 4 10 which which PRON xd07gq70365 4 11 often often ADV xd07gq70365 4 12 starts start VERB xd07gq70365 4 13 from from ADP xd07gq70365 4 14 epithelial epithelial ADJ xd07gq70365 4 15 cells cell NOUN xd07gq70365 4 16 . . PUNCT xd07gq70365 5 1 despite despite SCONJ xd07gq70365 5 2 their their PRON xd07gq70365 5 3 importance importance NOUN xd07gq70365 5 4 , , PUNCT xd07gq70365 5 5 the the DET xd07gq70365 5 6 exact exact ADJ xd07gq70365 5 7 mechanisms mechanism NOUN xd07gq70365 5 8 that that PRON xd07gq70365 5 9 control control VERB xd07gq70365 5 10 proliferation proliferation NOUN xd07gq70365 5 11 is be AUX xd07gq70365 5 12 still still ADV xd07gq70365 5 13 under under ADP xd07gq70365 5 14 debate debate NOUN xd07gq70365 5 15 . . PUNCT xd07gq70365 6 1 some some PRON xd07gq70365 6 2 believe believe VERB xd07gq70365 6 3 that that SCONJ xd07gq70365 6 4 mechanical mechanical ADJ xd07gq70365 6 5 feedback feedback NOUN xd07gq70365 6 6 plays play VERB xd07gq70365 6 7 the the DET xd07gq70365 6 8 most most ADV xd07gq70365 6 9 important important ADJ xd07gq70365 6 10 role role NOUN xd07gq70365 6 11 in in ADP xd07gq70365 6 12 growth growth NOUN xd07gq70365 6 13 regulation regulation NOUN xd07gq70365 6 14 , , PUNCT xd07gq70365 6 15 while while SCONJ xd07gq70365 6 16 others other NOUN xd07gq70365 6 17 believe believe VERB xd07gq70365 6 18 that that SCONJ xd07gq70365 6 19 signaling signal VERB xd07gq70365 6 20 molecules molecule NOUN xd07gq70365 6 21 could could AUX xd07gq70365 6 22 be be AUX xd07gq70365 6 23 responsible responsible ADJ xd07gq70365 6 24 for for ADP xd07gq70365 6 25 regulation regulation NOUN xd07gq70365 6 26 of of ADP xd07gq70365 6 27 growth growth NOUN xd07gq70365 6 28 pattern pattern NOUN xd07gq70365 6 29 . . PUNCT xd07gq70365 7 1 computational computational ADJ xd07gq70365 7 2 modeling modeling NOUN xd07gq70365 7 3 is be AUX xd07gq70365 7 4 used use VERB xd07gq70365 7 5 in in ADP xd07gq70365 7 6 this this DET xd07gq70365 7 7 study study NOUN xd07gq70365 7 8 to to PART xd07gq70365 7 9 provide provide VERB xd07gq70365 7 10 new new ADJ xd07gq70365 7 11 insights insight NOUN xd07gq70365 7 12 into into ADP xd07gq70365 7 13 cellular cellular ADJ xd07gq70365 7 14 growth growth NOUN xd07gq70365 7 15 regulation regulation NOUN xd07gq70365 7 16 . . PUNCT xd07gq70365 8 1 up up ADP xd07gq70365 8 2 to to ADP xd07gq70365 8 3 date date NOUN xd07gq70365 8 4 , , PUNCT xd07gq70365 8 5 various various ADJ xd07gq70365 8 6 approaches approach NOUN xd07gq70365 8 7 have have AUX xd07gq70365 8 8 been be AUX xd07gq70365 8 9 employed employ VERB xd07gq70365 8 10 to to PART xd07gq70365 8 11 model model VERB xd07gq70365 8 12 the the DET xd07gq70365 8 13 proliferation proliferation NOUN xd07gq70365 8 14 of of ADP xd07gq70365 8 15 epithelial epithelial ADJ xd07gq70365 8 16 cells cell NOUN xd07gq70365 8 17 . . PUNCT xd07gq70365 9 1 there there PRON xd07gq70365 9 2 are be VERB xd07gq70365 9 3 topological topological ADJ xd07gq70365 9 4 models model NOUN xd07gq70365 9 5 that that PRON xd07gq70365 9 6 emphasize emphasize VERB xd07gq70365 9 7 cellular cellular ADJ xd07gq70365 9 8 connectivity connectivity NOUN xd07gq70365 9 9 , , PUNCT xd07gq70365 9 10 lattice lattice NOUN xd07gq70365 9 11 - - PUNCT xd07gq70365 9 12 based base VERB xd07gq70365 9 13 models model NOUN xd07gq70365 9 14 that that PRON xd07gq70365 9 15 use use VERB xd07gq70365 9 16 fixed fix VERB xd07gq70365 9 17 lattice lattice NOUN xd07gq70365 9 18 to to PART xd07gq70365 9 19 represent represent VERB xd07gq70365 9 20 cells cell NOUN xd07gq70365 9 21 , , PUNCT xd07gq70365 9 22 and and CCONJ xd07gq70365 9 23 off off ADP xd07gq70365 9 24 - - PUNCT xd07gq70365 9 25 lattice lattice NOUN xd07gq70365 9 26 models model NOUN xd07gq70365 9 27 that that PRON xd07gq70365 9 28 describe describe VERB xd07gq70365 9 29 cells cell NOUN xd07gq70365 9 30 by by ADP xd07gq70365 9 31 collection collection NOUN xd07gq70365 9 32 of of ADP xd07gq70365 9 33 connected connected ADJ xd07gq70365 9 34 points point NOUN xd07gq70365 9 35 . . PUNCT xd07gq70365 10 1 however however ADV xd07gq70365 10 2 , , PUNCT xd07gq70365 10 3 existing existing ADJ xd07gq70365 10 4 models model NOUN xd07gq70365 10 5 are be AUX xd07gq70365 10 6 insufficient insufficient ADJ xd07gq70365 10 7 to to PART xd07gq70365 10 8 capture capture VERB xd07gq70365 10 9 mechanical mechanical ADJ xd07gq70365 10 10 properties property NOUN xd07gq70365 10 11 of of ADP xd07gq70365 10 12 the the DET xd07gq70365 10 13 epithelial epithelial ADJ xd07gq70365 10 14 sheet sheet NOUN xd07gq70365 10 15 , , PUNCT xd07gq70365 10 16 partially partially ADV xd07gq70365 10 17 because because SCONJ xd07gq70365 10 18 of of ADP xd07gq70365 10 19 the the DET xd07gq70365 10 20 artificially artificially ADV xd07gq70365 10 21 imposed impose VERB xd07gq70365 10 22 geometrical geometrical ADJ xd07gq70365 10 23 constraints constraint NOUN xd07gq70365 10 24 , , PUNCT xd07gq70365 10 25 which which PRON xd07gq70365 10 26 often often ADV xd07gq70365 10 27 restrict restrict VERB xd07gq70365 10 28 cells cell NOUN xd07gq70365 10 29 to to PART xd07gq70365 10 30 be be AUX xd07gq70365 10 31 polygon polygon NOUN xd07gq70365 10 32 - - PUNCT xd07gq70365 10 33 shaped shape VERB xd07gq70365 10 34 . . PUNCT xd07gq70365 11 1 moreover moreover ADV xd07gq70365 11 2 , , PUNCT xd07gq70365 11 3 the the DET xd07gq70365 11 4 mechanical mechanical ADJ xd07gq70365 11 5 interaction interaction NOUN xd07gq70365 11 6 between between ADP xd07gq70365 11 7 cells cell NOUN xd07gq70365 11 8 might might AUX xd07gq70365 11 9 be be AUX xd07gq70365 11 10 over over ADV xd07gq70365 11 11 - - PUNCT xd07gq70365 11 12 simplified simplify VERB xd07gq70365 11 13 because because SCONJ xd07gq70365 11 14 of of ADP xd07gq70365 11 15 this this DET xd07gq70365 11 16 approximation approximation NOUN xd07gq70365 11 17 . . PUNCT xd07gq70365 12 1 a a DET xd07gq70365 12 2 novel novel ADJ xd07gq70365 12 3 cell cell NOUN xd07gq70365 12 4 - - PUNCT xd07gq70365 12 5 based base VERB xd07gq70365 12 6 off off ADP xd07gq70365 12 7 - - PUNCT xd07gq70365 12 8 lattice lattice NOUN xd07gq70365 12 9 computational computational ADJ xd07gq70365 12 10 model model NOUN xd07gq70365 12 11 for for ADP xd07gq70365 12 12 studying study VERB xd07gq70365 12 13 epithelial epithelial ADJ xd07gq70365 12 14 proliferation proliferation NOUN xd07gq70365 12 15 is be AUX xd07gq70365 12 16 developed develop VERB xd07gq70365 12 17 in in ADP xd07gq70365 12 18 this this DET xd07gq70365 12 19 study study NOUN xd07gq70365 12 20 . . PUNCT xd07gq70365 13 1 the the DET xd07gq70365 13 2 model model NOUN xd07gq70365 13 3 provides provide VERB xd07gq70365 13 4 a a DET xd07gq70365 13 5 flexible flexible ADJ xd07gq70365 13 6 representation representation NOUN xd07gq70365 13 7 for for ADP xd07gq70365 13 8 cellular cellular ADJ xd07gq70365 13 9 geometry geometry NOUN xd07gq70365 13 10 , , PUNCT xd07gq70365 13 11 without without ADP xd07gq70365 13 12 imposing impose VERB xd07gq70365 13 13 assumption assumption NOUN xd07gq70365 13 14 of of ADP xd07gq70365 13 15 polygon polygon NOUN xd07gq70365 13 16 cell cell NOUN xd07gq70365 13 17 shape shape NOUN xd07gq70365 13 18 . . PUNCT xd07gq70365 14 1 epithelial epithelial ADJ xd07gq70365 14 2 cells cell NOUN xd07gq70365 14 3 appear appear VERB xd07gq70365 14 4 as as SCONJ xd07gq70365 14 5 polygon polygon NOUN xd07gq70365 14 6 - - PUNCT xd07gq70365 14 7 shaped shape VERB xd07gq70365 14 8 in in ADP xd07gq70365 14 9 model model NOUN xd07gq70365 14 10 simulations simulation NOUN xd07gq70365 14 11 as as ADP xd07gq70365 14 12 a a DET xd07gq70365 14 13 result result NOUN xd07gq70365 14 14 of of ADP xd07gq70365 14 15 mechanical mechanical ADJ xd07gq70365 14 16 interaction interaction NOUN xd07gq70365 14 17 . . PUNCT xd07gq70365 15 1 cellular cellular ADJ xd07gq70365 15 2 network network NOUN xd07gq70365 15 3 transitions transition NOUN xd07gq70365 15 4 in in ADP xd07gq70365 15 5 model model NOUN xd07gq70365 15 6 simulations simulation NOUN xd07gq70365 15 7 also also ADV xd07gq70365 15 8 naturally naturally ADV xd07gq70365 15 9 emerge emerge VERB xd07gq70365 15 10 as as ADP xd07gq70365 15 11 a a DET xd07gq70365 15 12 result result NOUN xd07gq70365 15 13 of of ADP xd07gq70365 15 14 cellular cellular ADJ xd07gq70365 15 15 interaction interaction NOUN xd07gq70365 15 16 , , PUNCT xd07gq70365 15 17 compared compare VERB xd07gq70365 15 18 with with ADP xd07gq70365 15 19 existing exist VERB xd07gq70365 15 20 models model NOUN xd07gq70365 15 21 which which PRON xd07gq70365 15 22 often often ADV xd07gq70365 15 23 include include VERB xd07gq70365 15 24 ad ad NOUN xd07gq70365 15 25 hoc hoc X xd07gq70365 15 26 assumptions assumption NOUN xd07gq70365 15 27 for for ADP xd07gq70365 15 28 such such ADJ xd07gq70365 15 29 transitions transition NOUN xd07gq70365 15 30 . . PUNCT xd07gq70365 16 1 results result NOUN xd07gq70365 16 2 in in ADP xd07gq70365 16 3 the the DET xd07gq70365 16 4 esem esem PROPN xd07gq70365 16 5 simulations simulation NOUN xd07gq70365 16 6 match match VERB xd07gq70365 16 7 very very ADV xd07gq70365 16 8 well well ADV xd07gq70365 16 9 with with ADP xd07gq70365 16 10 experimental experimental ADJ xd07gq70365 16 11 findings finding NOUN xd07gq70365 16 12 , , PUNCT xd07gq70365 16 13 such such ADJ xd07gq70365 16 14 as as ADP xd07gq70365 16 15 overall overall ADJ xd07gq70365 16 16 cell cell NOUN xd07gq70365 16 17 shape shape NOUN xd07gq70365 16 18 polygon polygon NOUN xd07gq70365 16 19 class class NOUN xd07gq70365 16 20 distribution distribution NOUN xd07gq70365 16 21 on on ADP xd07gq70365 16 22 the the DET xd07gq70365 16 23 epithelial epithelial ADJ xd07gq70365 16 24 sheet sheet NOUN xd07gq70365 16 25 , , PUNCT xd07gq70365 16 26 and and CCONJ xd07gq70365 16 27 the the DET xd07gq70365 16 28 shifting shifting NOUN xd07gq70365 16 29 of of ADP xd07gq70365 16 30 polygon polygon NOUN xd07gq70365 16 31 class class NOUN xd07gq70365 16 32 during during ADP xd07gq70365 16 33 mitosis mitosis NOUN xd07gq70365 16 34 . . PUNCT xd07gq70365 17 1 it it PRON xd07gq70365 17 2 is be AUX xd07gq70365 17 3 also also ADV xd07gq70365 17 4 worth worth ADJ xd07gq70365 17 5 mentioning mention VERB xd07gq70365 17 6 that that SCONJ xd07gq70365 17 7 the the DET xd07gq70365 17 8 new new ADJ xd07gq70365 17 9 model model NOUN xd07gq70365 17 10 reproduces reproduce VERB xd07gq70365 17 11 mitotic mitotic ADJ xd07gq70365 17 12 rounding round VERB xd07gq70365 17 13 behavior behavior NOUN xd07gq70365 17 14 in in ADP xd07gq70365 17 15 proliferating proliferate VERB xd07gq70365 17 16 epithelia epithelia PROPN xd07gq70365 17 17 , , PUNCT xd07gq70365 17 18 which which PRON xd07gq70365 17 19 is be AUX xd07gq70365 17 20 commonly commonly ADV xd07gq70365 17 21 observed observe VERB xd07gq70365 17 22 but but CCONJ xd07gq70365 17 23 never never ADV xd07gq70365 17 24 been be AUX xd07gq70365 17 25 modeled model VERB xd07gq70365 17 26 in in ADP xd07gq70365 17 27 other other ADJ xd07gq70365 17 28 computational computational ADJ xd07gq70365 17 29 models model NOUN xd07gq70365 17 30 . . PUNCT xd07gq70365 18 1 in in ADP xd07gq70365 18 2 addition addition NOUN xd07gq70365 18 3 , , PUNCT xd07gq70365 18 4 this this DET xd07gq70365 18 5 thesis thesis NOUN xd07gq70365 18 6 introduces introduce VERB xd07gq70365 18 7 a a DET xd07gq70365 18 8 parallel parallel ADJ xd07gq70365 18 9 algorithm algorithm NOUN xd07gq70365 18 10 that that PRON xd07gq70365 18 11 runs run VERB xd07gq70365 18 12 on on ADP xd07gq70365 18 13 general general ADJ xd07gq70365 18 14 purpose purpose NOUN xd07gq70365 18 15 graphical graphical ADJ xd07gq70365 18 16 processing processing NOUN xd07gq70365 18 17 unit unit NOUN xd07gq70365 18 18 for for ADP xd07gq70365 18 19 model model NOUN xd07gq70365 18 20 implementation implementation NOUN xd07gq70365 18 21 , , PUNCT xd07gq70365 18 22 overcoming overcome VERB xd07gq70365 18 23 computational computational ADJ xd07gq70365 18 24 challenges challenge NOUN xd07gq70365 18 25 brought bring VERB xd07gq70365 18 26 by by ADP xd07gq70365 18 27 the the DET xd07gq70365 18 28 new new ADJ xd07gq70365 18 29 model model NOUN xd07gq70365 18 30 . . PUNCT xd07gq70365 19 1 a a DET xd07gq70365 19 2 complete complete ADJ xd07gq70365 19 3 source source NOUN xd07gq70365 19 4 code code NOUN xd07gq70365 19 5 package package NOUN xd07gq70365 19 6 of of ADP xd07gq70365 19 7 the the DET xd07gq70365 19 8 parallel parallel ADJ xd07gq70365 19 9 algorithm algorithm PROPN xd07gq70365 19 10 is be AUX xd07gq70365 19 11 provided provide VERB xd07gq70365 19 12 as as ADP xd07gq70365 19 13 a a DET xd07gq70365 19 14 supplement supplement NOUN xd07gq70365 19 15 of of ADP xd07gq70365 19 16 this this DET xd07gq70365 19 17 thesis thesis NOUN xd07gq70365 19 18 for for ADP xd07gq70365 19 19 future future ADJ xd07gq70365 19 20 extension extension NOUN xd07gq70365 19 21 and and CCONJ xd07gq70365 19 22 development development NOUN xd07gq70365 19 23 of of ADP xd07gq70365 19 24 the the DET xd07gq70365 19 25 model model NOUN xd07gq70365 19 26 . . PUNCT xd07gq70365 20 1 this this DET xd07gq70365 20 2 work work NOUN xd07gq70365 20 3 was be AUX xd07gq70365 20 4 supported support VERB xd07gq70365 20 5 in in ADP xd07gq70365 20 6 part part NOUN xd07gq70365 20 7 by by ADP xd07gq70365 20 8 the the DET xd07gq70365 20 9 national national PROPN xd07gq70365 20 10 science science PROPN xd07gq70365 20 11 foundation foundation PROPN xd07gq70365 20 12 grant grant PROPN xd07gq70365 20 13 cbet cbet PROPN xd07gq70365 20 14 1403887 1403887 NUM xd07gq70365 20 15 . . PUNCT