id sid tid token lemma pos x920ft86t62 1 1 conantokins conantokin NOUN x920ft86t62 1 2 , , PUNCT x920ft86t62 1 3 which which PRON x920ft86t62 1 4 are be AUX x920ft86t62 1 5 neuroactive neuroactive ADJ x920ft86t62 1 6 peptides peptide NOUN x920ft86t62 1 7 found find VERB x920ft86t62 1 8 in in ADP x920ft86t62 1 9 the the DET x920ft86t62 1 10 venom venom NOUN x920ft86t62 1 11 of of ADP x920ft86t62 1 12 marine marine ADJ x920ft86t62 1 13 snails snail NOUN x920ft86t62 1 14 , , PUNCT x920ft86t62 1 15 contain contain VERB x920ft86t62 1 16 post post ADJ x920ft86t62 1 17 - - ADJ x920ft86t62 1 18 translationally translationally ADV x920ft86t62 1 19 modified modify VERB x920ft86t62 1 20 & & CCONJ x920ft86t62 1 21 gamma gamma NOUN x920ft86t62 1 22 - - PUNCT x920ft86t62 1 23 carboxyglutamate carboxyglutamate ADJ x920ft86t62 1 24 residues residue NOUN x920ft86t62 1 25 ( ( PUNCT x920ft86t62 1 26 gla gla PROPN x920ft86t62 1 27 ; ; PUNCT x920ft86t62 1 28 & & CCONJ x920ft86t62 1 29 # # SYM x920ft86t62 1 30 947 947 NUM x920ft86t62 1 31 ;) ;) NUM x920ft86t62 1 32 . . PUNCT x920ft86t62 2 1 the the DET x920ft86t62 2 2 gla gla PROPN x920ft86t62 2 3 residues residue NOUN x920ft86t62 2 4 are be AUX x920ft86t62 2 5 integral integral ADJ x920ft86t62 2 6 for for ADP x920ft86t62 2 7 their their PRON x920ft86t62 2 8 structure structure NOUN x920ft86t62 2 9 , , PUNCT x920ft86t62 2 10 function function NOUN x920ft86t62 2 11 , , PUNCT x920ft86t62 2 12 and and CCONJ x920ft86t62 2 13 subunit subunit NOUN x920ft86t62 2 14 - - PUNCT x920ft86t62 2 15 selective selective ADJ x920ft86t62 2 16 antagonism antagonism NOUN x920ft86t62 2 17 of of ADP x920ft86t62 2 18 ion ion NOUN x920ft86t62 2 19 channels channel NOUN x920ft86t62 2 20 of of ADP x920ft86t62 2 21 the the DET x920ft86t62 2 22 n n PROPN x920ft86t62 2 23 - - PUNCT x920ft86t62 2 24 methyl methyl NOUN x920ft86t62 2 25 - - PUNCT x920ft86t62 2 26 d d NOUN x920ft86t62 2 27 - - PUNCT x920ft86t62 2 28 aspartate aspartate NOUN x920ft86t62 2 29 receptors receptor NOUN x920ft86t62 2 30 ( ( PUNCT x920ft86t62 2 31 nmdar nmdar ADV x920ft86t62 2 32 ) ) PUNCT x920ft86t62 2 33 . . PUNCT x920ft86t62 3 1 the the DET x920ft86t62 3 2 functional functional ADJ x920ft86t62 3 3 heterotetramer heterotetramer NOUN x920ft86t62 3 4 of of ADP x920ft86t62 3 5 the the DET x920ft86t62 3 6 receptor receptor NOUN x920ft86t62 3 7 is be AUX x920ft86t62 3 8 composed compose VERB x920ft86t62 3 9 of of ADP x920ft86t62 3 10 glun1 glun1 NOUN x920ft86t62 3 11 and and CCONJ x920ft86t62 3 12 glun2 glun2 NOUN x920ft86t62 3 13 subunits subunit NOUN x920ft86t62 3 14 which which PRON x920ft86t62 3 15 impart impart VERB x920ft86t62 3 16 specific specific ADJ x920ft86t62 3 17 biochemical biochemical ADJ x920ft86t62 3 18 and and CCONJ x920ft86t62 3 19 physiological physiological ADJ x920ft86t62 3 20 properties property NOUN x920ft86t62 3 21 to to ADP x920ft86t62 3 22 the the DET x920ft86t62 3 23 ion ion NOUN x920ft86t62 3 24 channels channel NOUN x920ft86t62 3 25 . . PUNCT x920ft86t62 4 1 the the DET x920ft86t62 4 2 optimum optimum ADJ x920ft86t62 4 3 spacing spacing NOUN x920ft86t62 4 4 of of ADP x920ft86t62 4 5 gla gla PROPN x920ft86t62 4 6 residues residue NOUN x920ft86t62 4 7 in in ADP x920ft86t62 4 8 conantokins conantokin NOUN x920ft86t62 4 9 stabilize stabilize VERB x920ft86t62 4 10 the the DET x920ft86t62 4 11 structure structure NOUN x920ft86t62 4 12 when when SCONJ x920ft86t62 4 13 complexed complexe VERB x920ft86t62 4 14 to to ADP x920ft86t62 4 15 divalent divalent ADJ x920ft86t62 4 16 ions ion NOUN x920ft86t62 4 17 and and CCONJ x920ft86t62 4 18 mediate mediate VERB x920ft86t62 4 19 nmdar nmdar NOUN x920ft86t62 4 20 - - PUNCT x920ft86t62 4 21 subunit subunit NOUN x920ft86t62 4 22 selective selective ADJ x920ft86t62 4 23 properties property NOUN x920ft86t62 4 24 . . PUNCT x920ft86t62 5 1 in in ADP x920ft86t62 5 2 this this DET x920ft86t62 5 3 study study NOUN x920ft86t62 5 4 , , PUNCT x920ft86t62 5 5 the the DET x920ft86t62 5 6 structural structural ADJ x920ft86t62 5 7 and and CCONJ x920ft86t62 5 8 antagonistic antagonistic ADJ x920ft86t62 5 9 properties property NOUN x920ft86t62 5 10 of of ADP x920ft86t62 5 11 conantokins conantokin NOUN x920ft86t62 5 12 conpr-1,-2 conpr-1,-2 SPACE x920ft86t62 5 13 , , PUNCT x920ft86t62 5 14 and and CCONJ x920ft86t62 5 15 -3 -3 X x920ft86t62 5 16 from from ADP x920ft86t62 5 17 conus conus NOUN x920ft86t62 5 18 parius parius NOUN x920ft86t62 5 19 and and CCONJ x920ft86t62 5 20 conrl conrl NOUN x920ft86t62 5 21 - - PUNCT x920ft86t62 5 22 b b PROPN x920ft86t62 5 23 from from ADP x920ft86t62 5 24 conus conus PROPN x920ft86t62 5 25 rolani rolani PROPN x920ft86t62 5 26 species specie NOUN x920ft86t62 5 27 were be AUX x920ft86t62 5 28 studied study VERB x920ft86t62 5 29 . . PUNCT x920ft86t62 6 1 the the DET x920ft86t62 6 2 conus conus NOUN x920ft86t62 6 3 parius parius NOUN x920ft86t62 6 4 family family NOUN x920ft86t62 6 5 of of ADP x920ft86t62 6 6 conantokin conantokin ADJ x920ft86t62 6 7 peptides peptide NOUN x920ft86t62 6 8 are be AUX x920ft86t62 6 9 glun2b glun2b PUNCT x920ft86t62 6 10 selective selective NOUN x920ft86t62 6 11 and and CCONJ x920ft86t62 6 12 adopt adopt VERB x920ft86t62 6 13 a a DET x920ft86t62 6 14 low low ADJ x920ft86t62 6 15 properties property NOUN x920ft86t62 6 16 of of ADP x920ft86t62 6 17 & & CCONJ x920ft86t62 6 18 # # SYM x920ft86t62 6 19 945;-helix 945;-helix NUM x920ft86t62 6 20 conformation conformation NOUN x920ft86t62 6 21 in in ADP x920ft86t62 6 22 the the DET x920ft86t62 6 23 presence presence NOUN x920ft86t62 6 24 of of ADP x920ft86t62 6 25 mg2 mg2 NOUN x920ft86t62 6 26 + + NOUN x920ft86t62 6 27 . . PUNCT x920ft86t62 7 1 these these DET x920ft86t62 7 2 peptides peptide NOUN x920ft86t62 7 3 also also ADV x920ft86t62 7 4 display display VERB x920ft86t62 7 5 the the DET x920ft86t62 7 6 ability ability NOUN x920ft86t62 7 7 to to PART x920ft86t62 7 8 diminish diminish VERB x920ft86t62 7 9 downstream downstream ADJ x920ft86t62 7 10 signaling signal VERB x920ft86t62 7 11 events event NOUN x920ft86t62 7 12 . . PUNCT x920ft86t62 8 1 conrl conrl PROPN x920ft86t62 8 2 - - PUNCT x920ft86t62 8 3 b b PROPN x920ft86t62 8 4 , , PUNCT x920ft86t62 8 5 conpr-2 conpr-2 PROPN x920ft86t62 8 6 , , PUNCT x920ft86t62 8 7 and and CCONJ x920ft86t62 8 8 conpr-3 conpr-3 PROPN x920ft86t62 8 9 , , PUNCT x920ft86t62 8 10 additionally additionally ADV x920ft86t62 8 11 contain contain VERB x920ft86t62 8 12 the the DET x920ft86t62 8 13 post post ADJ x920ft86t62 8 14 - - ADJ x920ft86t62 8 15 translationally translationally ADV x920ft86t62 8 16 modified modify VERB x920ft86t62 8 17 4 4 NUM x920ft86t62 8 18 - - PUNCT x920ft86t62 8 19 transhydroxyproline transhydroxyproline NOUN x920ft86t62 8 20 ( ( PUNCT x920ft86t62 8 21 hyp hyp PROPN x920ft86t62 8 22 ; ; PUNCT x920ft86t62 8 23 o o NUM x920ft86t62 8 24 ) ) PUNCT x920ft86t62 8 25 residue residue NOUN x920ft86t62 8 26 . . PUNCT x920ft86t62 9 1 the the DET x920ft86t62 9 2 hyp10 hyp10 ADJ x920ft86t62 9 3 residue residue NOUN x920ft86t62 9 4 in in ADP x920ft86t62 9 5 conrl conrl NOUN x920ft86t62 9 6 - - PUNCT x920ft86t62 9 7 b b NOUN x920ft86t62 9 8 , , PUNCT x920ft86t62 9 9 not not PART x920ft86t62 9 10 only only ADV x920ft86t62 9 11 changes change VERB x920ft86t62 9 12 the the DET x920ft86t62 9 13 gla gla PROPN x920ft86t62 9 14 positioning positioning NOUN x920ft86t62 9 15 in in ADP x920ft86t62 9 16 the the DET x920ft86t62 9 17 c c NOUN x920ft86t62 9 18 - - PUNCT x920ft86t62 9 19 terminal terminal ADJ x920ft86t62 9 20 part part NOUN x920ft86t62 9 21 of of ADP x920ft86t62 9 22 conrl conrl NOUN x920ft86t62 9 23 - - PUNCT x920ft86t62 9 24 b b NOUN x920ft86t62 9 25 , , PUNCT x920ft86t62 9 26 but but CCONJ x920ft86t62 9 27 also also ADV x920ft86t62 9 28 affects affect VERB x920ft86t62 9 29 the the DET x920ft86t62 9 30 structural structural ADJ x920ft86t62 9 31 properties property NOUN x920ft86t62 9 32 of of ADP x920ft86t62 9 33 the the DET x920ft86t62 9 34 peptide peptide NOUN x920ft86t62 9 35 . . PUNCT x920ft86t62 10 1 a a DET x920ft86t62 10 2 combination combination NOUN x920ft86t62 10 3 of of ADP x920ft86t62 10 4 biophysical biophysical ADJ x920ft86t62 10 5 techniques technique NOUN x920ft86t62 10 6 , , PUNCT x920ft86t62 10 7 e.g. e.g. X x920ft86t62 10 8 , , PUNCT x920ft86t62 10 9 cd cd PROPN x920ft86t62 10 10 , , PUNCT x920ft86t62 10 11 1h 1h NOUN x920ft86t62 10 12 nmr nmr PROPN x920ft86t62 10 13 and and CCONJ x920ft86t62 10 14 itc itc PROPN x920ft86t62 10 15 , , PUNCT x920ft86t62 10 16 was be AUX x920ft86t62 10 17 employed employ VERB x920ft86t62 10 18 to to PART x920ft86t62 10 19 study study VERB x920ft86t62 10 20 the the DET x920ft86t62 10 21 structure structure NOUN x920ft86t62 10 22 and and CCONJ x920ft86t62 10 23 metal metal NOUN x920ft86t62 10 24 binding bind VERB x920ft86t62 10 25 properties property NOUN x920ft86t62 10 26 of of ADP x920ft86t62 10 27 mg2+/conrl mg2+/conrl PROPN x920ft86t62 10 28 - - PUNCT x920ft86t62 10 29 b. b. PROPN x920ft86t62 10 30 the the DET x920ft86t62 10 31 structure structure NOUN x920ft86t62 10 32 determined determine VERB x920ft86t62 10 33 by by ADP x920ft86t62 10 34 high high ADJ x920ft86t62 10 35 - - PUNCT x920ft86t62 10 36 field field NOUN x920ft86t62 10 37 1h 1h NOUN x920ft86t62 10 38 nmr nmr NOUN x920ft86t62 10 39 , , PUNCT x920ft86t62 10 40 shows show VERB x920ft86t62 10 41 disruption disruption NOUN x920ft86t62 10 42 in in ADP x920ft86t62 10 43 the the PRON x920ft86t62 10 44 & & CCONJ x920ft86t62 10 45 # # SYM x920ft86t62 10 46 945;-helix 945;-helix NUM x920ft86t62 10 47 due due ADP x920ft86t62 10 48 to to ADP x920ft86t62 10 49 hyp10 hyp10 PROPN x920ft86t62 10 50 further far ADV x920ft86t62 10 51 interfering interfere VERB x920ft86t62 10 52 with with ADP x920ft86t62 10 53 mg2 mg2 ADJ x920ft86t62 10 54 + + NOUN x920ft86t62 10 55 -binding -binding NOUN x920ft86t62 10 56 , , PUNCT x920ft86t62 10 57 thus thus ADV x920ft86t62 10 58 resulting result VERB x920ft86t62 10 59 in in ADP x920ft86t62 10 60 solvent solvent ADJ x920ft86t62 10 61 accessible accessible ADJ x920ft86t62 10 62 backbone backbone PROPN x920ft86t62 10 63 amide amide PROPN x920ft86t62 10 64 protons protons PROPN x920ft86t62 10 65 . . PUNCT x920ft86t62 11 1 to to PART x920ft86t62 11 2 assess assess VERB x920ft86t62 11 3 the the DET x920ft86t62 11 4 role role NOUN x920ft86t62 11 5 of of ADP x920ft86t62 11 6 hyp hyp PROPN x920ft86t62 11 7 and and CCONJ x920ft86t62 11 8 the the DET x920ft86t62 11 9 molecular molecular ADJ x920ft86t62 11 10 requisites requisite NOUN x920ft86t62 11 11 for for ADP x920ft86t62 11 12 the the DET x920ft86t62 11 13 unique unique ADJ x920ft86t62 11 14 structural structural ADJ x920ft86t62 11 15 and and CCONJ x920ft86t62 11 16 functional functional ADJ x920ft86t62 11 17 properties property NOUN x920ft86t62 11 18 of of ADP x920ft86t62 11 19 conrl conrl NOUN x920ft86t62 11 20 - - PUNCT x920ft86t62 11 21 b b NOUN x920ft86t62 11 22 , , PUNCT x920ft86t62 11 23 mutant mutant ADJ x920ft86t62 11 24 peptides peptide NOUN x920ft86t62 11 25 , , PUNCT x920ft86t62 11 26 cong[10 cong[10 NOUN x920ft86t62 11 27 & & CCONJ x920ft86t62 11 28 # # SYM x920ft86t62 11 29 9660;o 9660;o NUM x920ft86t62 11 30 ] ] PUNCT x920ft86t62 11 31 and and CCONJ x920ft86t62 11 32 conrl conrl NOUN x920ft86t62 11 33 - - PUNCT x920ft86t62 11 34 b[Δkao▼nq b[Δkao▼nq NOUN x920ft86t62 11 35 ] ] PUNCT x920ft86t62 11 36 were be AUX x920ft86t62 11 37 synthesized synthesize VERB x920ft86t62 11 38 . . PUNCT x920ft86t62 12 1 although although SCONJ x920ft86t62 12 2 , , PUNCT x920ft86t62 12 3 the the DET x920ft86t62 12 4 3d 3d NOUN x920ft86t62 12 5 structure structure NOUN x920ft86t62 12 6 and and CCONJ x920ft86t62 12 7 mg2 mg2 ADJ x920ft86t62 12 8 + + ADJ x920ft86t62 12 9 binding bind VERB x920ft86t62 12 10 abilities ability NOUN x920ft86t62 12 11 of of ADP x920ft86t62 12 12 conrl conrl NOUN x920ft86t62 12 13 - - PUNCT x920ft86t62 12 14 b[Δkao▼nq b[Δkao▼nq NOUN x920ft86t62 12 15 ] ] PUNCT x920ft86t62 12 16 were be AUX x920ft86t62 12 17 similar similar ADJ x920ft86t62 12 18 to to ADP x920ft86t62 12 19 con con NOUN x920ft86t62 12 20 - - PUNCT x920ft86t62 12 21 g g PROPN x920ft86t62 12 22 , , PUNCT x920ft86t62 12 23 this this DET x920ft86t62 12 24 peptide peptide NOUN x920ft86t62 12 25 displays display VERB x920ft86t62 12 26 complete complete VERB x920ft86t62 12 27 non non ADJ x920ft86t62 12 28 - - ADJ x920ft86t62 12 29 selectivity selectivity ADJ x920ft86t62 12 30 towards towards ADP x920ft86t62 12 31 nmdar nmdar PROPN x920ft86t62 12 32 . . PUNCT x920ft86t62 13 1 local local ADJ x920ft86t62 13 2 disruption disruption NOUN x920ft86t62 13 3 of of ADP x920ft86t62 13 4 the the DET x920ft86t62 13 5 & & CCONJ x920ft86t62 13 6 # # SYM x920ft86t62 13 7 945 945 NUM x920ft86t62 13 8 - - PUNCT x920ft86t62 13 9 helix helix NOUN x920ft86t62 13 10 backbone backbone NOUN x920ft86t62 13 11 in in ADP x920ft86t62 13 12 con con PROPN x920ft86t62 13 13 - - PUNCT x920ft86t62 13 14 g g NOUN x920ft86t62 13 15 on on ADP x920ft86t62 13 16 the the DET x920ft86t62 13 17 introduction introduction NOUN x920ft86t62 13 18 of of ADP x920ft86t62 13 19 hyp hyp PROPN x920ft86t62 13 20 , , PUNCT x920ft86t62 13 21 differs differ VERB x920ft86t62 13 22 from from ADP x920ft86t62 13 23 that that PRON x920ft86t62 13 24 of of ADP x920ft86t62 13 25 conrl conrl PROPN x920ft86t62 13 26 - - PUNCT x920ft86t62 13 27 b. b. PROPN x920ft86t62 13 28 additionally additionally ADV x920ft86t62 13 29 , , PUNCT x920ft86t62 13 30 con con PROPN x920ft86t62 13 31 - - PUNCT x920ft86t62 13 32 g[10 g[10 NOUN x920ft86t62 13 33 & & CCONJ x920ft86t62 13 34 # # SYM x920ft86t62 13 35 9660;o 9660;o NUM x920ft86t62 13 36 ] ] PUNCT x920ft86t62 13 37 loses lose VERB x920ft86t62 13 38 selectivity selectivity NOUN x920ft86t62 13 39 towards towards ADP x920ft86t62 13 40 ion ion NOUN x920ft86t62 13 41 channels channel NOUN x920ft86t62 13 42 containing contain VERB x920ft86t62 13 43 the the DET x920ft86t62 13 44 glun2b glun2b PROPN x920ft86t62 13 45 subunit subunit NOUN x920ft86t62 13 46 . . PUNCT x920ft86t62 14 1 these these DET x920ft86t62 14 2 results result NOUN x920ft86t62 14 3 suggest suggest VERB x920ft86t62 14 4 that that SCONJ x920ft86t62 14 5 the the DET x920ft86t62 14 6 natural natural ADJ x920ft86t62 14 7 occurrence occurrence NOUN x920ft86t62 14 8 of of ADP x920ft86t62 14 9 hyp hyp PROPN x920ft86t62 14 10 in in ADP x920ft86t62 14 11 the the DET x920ft86t62 14 12 conrl conrl NOUN x920ft86t62 14 13 - - PUNCT x920ft86t62 14 14 b b NOUN x920ft86t62 14 15 backbone backbone NOUN x920ft86t62 14 16 is be AUX x920ft86t62 14 17 important important ADJ x920ft86t62 14 18 for for ADP x920ft86t62 14 19 high high ADJ x920ft86t62 14 20 glun2b glun2b PROPN x920ft86t62 14 21 selectivity selectivity NOUN x920ft86t62 14 22 . . PUNCT x920ft86t62 15 1 in in ADP x920ft86t62 15 2 conclusion conclusion NOUN x920ft86t62 15 3 , , PUNCT x920ft86t62 15 4 the the DET x920ft86t62 15 5 presence presence NOUN x920ft86t62 15 6 of of ADP x920ft86t62 15 7 hyp hyp NOUN x920ft86t62 15 8 residue residue NOUN x920ft86t62 15 9 changes change VERB x920ft86t62 15 10 the the DET x920ft86t62 15 11 structural structural ADJ x920ft86t62 15 12 and and CCONJ x920ft86t62 15 13 functional functional ADJ x920ft86t62 15 14 properties property NOUN x920ft86t62 15 15 of of ADP x920ft86t62 15 16 conantokins conantokin NOUN x920ft86t62 15 17 . . PUNCT