id sid tid token lemma pos x059c53702z 1 1 anxiety anxiety NOUN x059c53702z 1 2 , , PUNCT x059c53702z 1 3 a a DET x059c53702z 1 4 debilitating debilitating ADJ x059c53702z 1 5 sense sense NOUN x059c53702z 1 6 of of ADP x059c53702z 1 7 fear fear NOUN x059c53702z 1 8 , , PUNCT x059c53702z 1 9 involves involve VERB x059c53702z 1 10 an an DET x059c53702z 1 11 interconnected interconnect VERB x059c53702z 1 12 brain brain NOUN x059c53702z 1 13 network network NOUN x059c53702z 1 14 that that PRON x059c53702z 1 15 includes include VERB x059c53702z 1 16 the the DET x059c53702z 1 17 medial medial ADJ x059c53702z 1 18 prefrontal prefrontal ADJ x059c53702z 1 19 cortex cortex NOUN x059c53702z 1 20 ( ( PUNCT x059c53702z 1 21 mpfc mpfc PROPN x059c53702z 1 22 ) ) PUNCT x059c53702z 1 23 , , PUNCT x059c53702z 1 24 amygdala amygdala NOUN x059c53702z 1 25 , , PUNCT x059c53702z 1 26 and and CCONJ x059c53702z 1 27 periaqueductal periaqueductal NOUN x059c53702z 1 28 grey grey NOUN x059c53702z 1 29 ( ( PUNCT x059c53702z 1 30 pag pag PROPN x059c53702z 1 31 ) ) PUNCT x059c53702z 1 32 . . PUNCT x059c53702z 2 1 however however ADV x059c53702z 2 2 , , PUNCT x059c53702z 2 3 the the DET x059c53702z 2 4 specific specific ADJ x059c53702z 2 5 organization organization NOUN x059c53702z 2 6 and and CCONJ x059c53702z 2 7 cellular cellular ADJ x059c53702z 2 8 physiology physiology NOUN x059c53702z 2 9 of of ADP x059c53702z 2 10 distinct distinct ADJ x059c53702z 2 11 pathways pathway NOUN x059c53702z 2 12 within within ADP x059c53702z 2 13 this this DET x059c53702z 2 14 network network NOUN x059c53702z 2 15 are be AUX x059c53702z 2 16 undefined undefined ADJ x059c53702z 2 17 but but CCONJ x059c53702z 2 18 critical critical ADJ x059c53702z 2 19 for for ADP x059c53702z 2 20 understanding understand VERB x059c53702z 2 21 anxiety anxiety NOUN x059c53702z 2 22 disorders disorder NOUN x059c53702z 2 23 . . PUNCT x059c53702z 3 1 this this DET x059c53702z 3 2 thesis thesis NOUN x059c53702z 3 3 elucidated elucidate VERB x059c53702z 3 4 the the DET x059c53702z 3 5 circuitry circuitry NOUN x059c53702z 3 6 , , PUNCT x059c53702z 3 7 pharmacology pharmacology NOUN x059c53702z 3 8 , , PUNCT x059c53702z 3 9 and and CCONJ x059c53702z 3 10 intrinsic intrinsic ADJ x059c53702z 3 11 physiology physiology NOUN x059c53702z 3 12 of of ADP x059c53702z 3 13 defined define VERB x059c53702z 3 14 pathways pathway NOUN x059c53702z 3 15 within within ADP x059c53702z 3 16 the the DET x059c53702z 3 17 mpfc mpfc NOUN x059c53702z 3 18 - - PUNCT x059c53702z 3 19 amygdala amygdala NOUN x059c53702z 3 20 - - PUNCT x059c53702z 3 21 pag pag PROPN x059c53702z 3 22 circuit circuit PROPN x059c53702z 3 23 . . PUNCT x059c53702z 4 1 comparison comparison NOUN x059c53702z 4 2 of of ADP x059c53702z 4 3 mpfc mpfc PROPN x059c53702z 4 4 neurons neuron NOUN x059c53702z 4 5 projecting project VERB x059c53702z 4 6 to to ADP x059c53702z 4 7 the the DET x059c53702z 4 8 pag pag PROPN x059c53702z 4 9 versus versus ADP x059c53702z 4 10 amygdala amygdala PROPN x059c53702z 4 11 revealed reveal VERB x059c53702z 4 12 significant significant ADJ x059c53702z 4 13 differences difference NOUN x059c53702z 4 14 in in ADP x059c53702z 4 15 intrinsic intrinsic ADJ x059c53702z 4 16 properties property NOUN x059c53702z 4 17 , , PUNCT x059c53702z 4 18 local local ADJ x059c53702z 4 19 circuitry circuitry NOUN x059c53702z 4 20 , , PUNCT x059c53702z 4 21 and and CCONJ x059c53702z 4 22 neuromodulation neuromodulation NOUN x059c53702z 4 23 by by ADP x059c53702z 4 24 stress stress NOUN x059c53702z 4 25 peptides peptide NOUN x059c53702z 4 26 . . PUNCT x059c53702z 5 1 in in ADP x059c53702z 5 2 the the DET x059c53702z 5 3 central central ADJ x059c53702z 5 4 amygdala amygdala NOUN x059c53702z 5 5 ( ( PUNCT x059c53702z 5 6 cea cea PROPN x059c53702z 5 7 ) ) PUNCT x059c53702z 5 8 , , PUNCT x059c53702z 5 9 neurons neuron NOUN x059c53702z 5 10 projecting project VERB x059c53702z 5 11 to to ADP x059c53702z 5 12 the the DET x059c53702z 5 13 pag pag PROPN x059c53702z 5 14 ( ( PUNCT x059c53702z 5 15 cea cea PROPN x059c53702z 5 16 - - PUNCT x059c53702z 5 17 pag pag PROPN x059c53702z 5 18 neurons neuron NOUN x059c53702z 5 19 ) ) PUNCT x059c53702z 5 20 expressed express VERB x059c53702z 5 21 different different ADJ x059c53702z 5 22 levels level NOUN x059c53702z 5 23 of of ADP x059c53702z 5 24 hyperpolarization hyperpolarization NOUN x059c53702z 5 25 - - PUNCT x059c53702z 5 26 activated activate VERB x059c53702z 5 27 current current NOUN x059c53702z 5 28 . . PUNCT x059c53702z 6 1 cea cea PROPN x059c53702z 6 2 - - PUNCT x059c53702z 6 3 pag pag PROPN x059c53702z 6 4 neurons neuron NOUN x059c53702z 6 5 were be AUX x059c53702z 6 6 altered alter VERB x059c53702z 6 7 by by ADP x059c53702z 6 8 anxiogenic anxiogenic ADJ x059c53702z 6 9 peptide peptide NOUN x059c53702z 6 10 corticotropin corticotropin NOUN x059c53702z 6 11 - - PUNCT x059c53702z 6 12 releasing release VERB x059c53702z 6 13 factor factor NOUN x059c53702z 6 14 ( ( PUNCT x059c53702z 6 15 crf crf PROPN x059c53702z 6 16 ) ) PUNCT x059c53702z 6 17 but but CCONJ x059c53702z 6 18 not not PART x059c53702z 6 19 anxiolytic anxiolytic ADJ x059c53702z 6 20 neuropeptide neuropeptide NOUN x059c53702z 6 21 - - PUNCT x059c53702z 6 22 y y PROPN x059c53702z 6 23 ( ( PUNCT x059c53702z 6 24 npy npy PROPN x059c53702z 6 25 ) ) PUNCT x059c53702z 6 26 . . PUNCT x059c53702z 7 1 optogenetic optogenetic ADJ x059c53702z 7 2 activation activation NOUN x059c53702z 7 3 of of ADP x059c53702z 7 4 axons axon NOUN x059c53702z 7 5 originating originate VERB x059c53702z 7 6 in in ADP x059c53702z 7 7 the the DET x059c53702z 7 8 pag pag PROPN x059c53702z 7 9 or or CCONJ x059c53702z 7 10 il il PROPN x059c53702z 7 11 drove drive VERB x059c53702z 7 12 both both CCONJ x059c53702z 7 13 excitation excitation NOUN x059c53702z 7 14 and and CCONJ x059c53702z 7 15 inhibition inhibition NOUN x059c53702z 7 16 in in ADP x059c53702z 7 17 cea cea PROPN x059c53702z 7 18 - - PUNCT x059c53702z 7 19 pag pag PROPN x059c53702z 7 20 neurons neuron NOUN x059c53702z 7 21 . . PUNCT x059c53702z 8 1 together together ADV x059c53702z 8 2 , , PUNCT x059c53702z 8 3 this this DET x059c53702z 8 4 thesis thesis NOUN x059c53702z 8 5 has have AUX x059c53702z 8 6 uncovered uncover VERB x059c53702z 8 7 critical critical ADJ x059c53702z 8 8 characteristics characteristic NOUN x059c53702z 8 9 of of ADP x059c53702z 8 10 a a DET x059c53702z 8 11 neural neural ADJ x059c53702z 8 12 network network NOUN x059c53702z 8 13 implicated implicate VERB x059c53702z 8 14 in in ADP x059c53702z 8 15 anxiety anxiety NOUN x059c53702z 8 16 . . PUNCT