id	sid	tid	token	lemma	pos
wh246q21940	1	1	the	the	DET
wh246q21940	1	2	adaptive	adaptive	ADJ
wh246q21940	1	3	immune	immune	ADJ
wh246q21940	1	4	system	system	NOUN
wh246q21940	1	5	provides	provide	VERB
wh246q21940	1	6	a	a	DET
wh246q21940	1	7	highly	highly	ADV
wh246q21940	1	8	specialized	specialized	ADJ
wh246q21940	1	9	pathway	pathway	NOUN
wh246q21940	1	10	,	,	PUNCT
wh246q21940	1	11	which	which	PRON
wh246q21940	1	12	can	can	AUX
wh246q21940	1	13	recognize	recognize	VERB
wh246q21940	1	14	and	and	CCONJ
wh246q21940	1	15	protect	protect	VERB
wh246q21940	1	16	against	against	ADP
wh246q21940	1	17	pathogens	pathogen	NOUN
wh246q21940	1	18	.	.	PUNCT
wh246q21940	2	1	the	the	DET
wh246q21940	2	2	cell	cell	NOUN
wh246q21940	2	3	-	-	PUNCT
wh246q21940	2	4	mediated	mediate	VERB
wh246q21940	2	5	immune	immune	ADJ
wh246q21940	2	6	response	response	NOUN
wh246q21940	2	7	is	be	AUX
wh246q21940	2	8	a	a	DET
wh246q21940	2	9	component	component	NOUN
wh246q21940	2	10	of	of	ADP
wh246q21940	2	11	the	the	DET
wh246q21940	2	12	adaptive	adaptive	ADJ
wh246q21940	2	13	immune	immune	ADJ
wh246q21940	2	14	system	system	NOUN
wh246q21940	2	15	which	which	PRON
wh246q21940	2	16	responds	respond	VERB
wh246q21940	2	17	to	to	ADP
wh246q21940	2	18	infected	infected	ADJ
wh246q21940	2	19	or	or	CCONJ
wh246q21940	2	20	aberrant	aberrant	ADJ
wh246q21940	2	21	cells	cell	NOUN
wh246q21940	2	22	.	.	PUNCT
wh246q21940	3	1	t	t	PROPN
wh246q21940	3	2	-	-	PUNCT
wh246q21940	3	3	cell	cell	NOUN
wh246q21940	3	4	receptors	receptor	NOUN
wh246q21940	3	5	(	(	PUNCT
wh246q21940	3	6	tcrs	tcrs	PROPN
wh246q21940	3	7	)	)	PUNCT
wh246q21940	3	8	are	be	AUX
wh246q21940	3	9	heterodimeric	heterodimeric	ADJ
wh246q21940	3	10	molecules	molecule	NOUN
wh246q21940	3	11	expressed	express	VERB
wh246q21940	3	12	on	on	ADP
wh246q21940	3	13	the	the	DET
wh246q21940	3	14	surface	surface	NOUN
wh246q21940	3	15	of	of	ADP
wh246q21940	3	16	t	t	NOUN
wh246q21940	3	17	lymphocytes	lymphocyte	NOUN
wh246q21940	3	18	.	.	PUNCT
wh246q21940	4	1	their	their	PRON
wh246q21940	4	2	function	function	NOUN
wh246q21940	4	3	is	be	AUX
wh246q21940	4	4	to	to	PART
wh246q21940	4	5	recognize	recognize	VERB
wh246q21940	4	6	peptide	peptide	NOUN
wh246q21940	4	7	antigens	antigen	NOUN
wh246q21940	4	8	presented	present	VERB
wh246q21940	4	9	on	on	ADP
wh246q21940	4	10	major	major	ADJ
wh246q21940	4	11	histocompatibility	histocompatibility	NOUN
wh246q21940	4	12	complex	complex	NOUN
wh246q21940	4	13	(	(	PUNCT
wh246q21940	4	14	mhc	mhc	NOUN
wh246q21940	4	15	)	)	PUNCT
wh246q21940	4	16	proteins	protein	NOUN
wh246q21940	4	17	,	,	PUNCT
wh246q21940	4	18	which	which	PRON
wh246q21940	4	19	are	be	AUX
wh246q21940	4	20	expressed	express	VERB
wh246q21940	4	21	on	on	ADP
wh246q21940	4	22	the	the	DET
wh246q21940	4	23	surface	surface	NOUN
wh246q21940	4	24	of	of	ADP
wh246q21940	4	25	antigen	antigen	NOUN
wh246q21940	4	26	presenting	present	VERB
wh246q21940	4	27	cells	cell	NOUN
wh246q21940	4	28	(	(	PUNCT
wh246q21940	4	29	apcs	apc	NOUN
wh246q21940	4	30	)	)	PUNCT
wh246q21940	4	31	.	.	PUNCT
wh246q21940	5	1	the	the	DET
wh246q21940	5	2	repertoire	repertoire	NOUN
wh246q21940	5	3	of	of	ADP
wh246q21940	5	4	tcrs	tcrs	NOUN
wh246q21940	5	5	is	be	AUX
wh246q21940	5	6	the	the	DET
wh246q21940	5	7	result	result	NOUN
wh246q21940	5	8	of	of	ADP
wh246q21940	5	9	the	the	DET
wh246q21940	5	10	thymic	thymic	ADJ
wh246q21940	5	11	education	education	NOUN
wh246q21940	5	12	process	process	NOUN
wh246q21940	5	13	during	during	ADP
wh246q21940	5	14	,	,	PUNCT
wh246q21940	5	15	which	which	PRON
wh246q21940	5	16	precursor	precursor	NOUN
wh246q21940	5	17	t	t	NOUN
wh246q21940	5	18	cells	cell	NOUN
wh246q21940	5	19	undergo	undergo	VERB
wh246q21940	5	20	both	both	PRON
wh246q21940	5	21	positive	positive	ADJ
wh246q21940	5	22	and	and	CCONJ
wh246q21940	5	23	negative	negative	ADJ
wh246q21940	5	24	selection	selection	NOUN
wh246q21940	5	25	to	to	PART
wh246q21940	5	26	acquire	acquire	VERB
wh246q21940	5	27	tolerance	tolerance	NOUN
wh246q21940	5	28	of	of	ADP
wh246q21940	5	29	self	self	NOUN
wh246q21940	5	30	-	-	PUNCT
wh246q21940	5	31	peptides	peptide	NOUN
wh246q21940	5	32	presented	present	VERB
wh246q21940	5	33	on	on	ADP
wh246q21940	5	34	self	self	NOUN
wh246q21940	5	35	-	-	PUNCT
wh246q21940	5	36	mhc	mhc	NOUN
wh246q21940	5	37	molecule	molecule	NOUN
wh246q21940	6	1	[	[	X
wh246q21940	6	2	1	1	NUM
wh246q21940	6	3	]	]	PUNCT
wh246q21940	6	4	.	.	PUNCT
wh246q21940	7	1	however	however	ADV
wh246q21940	7	2	,	,	PUNCT
wh246q21940	7	3	tcrs	tcr	NOUN
wh246q21940	7	4	are	be	AUX
wh246q21940	7	5	capable	capable	ADJ
wh246q21940	7	6	of	of	ADP
wh246q21940	7	7	responding	respond	VERB
wh246q21940	7	8	to	to	ADP
wh246q21940	7	9	foreign	foreign	ADJ
wh246q21940	7	10	or	or	CCONJ
wh246q21940	7	11	non	non	ADJ
wh246q21940	7	12	-	-	ADJ
wh246q21940	7	13	self	self	ADJ
wh246q21940	7	14	mhc	mhc	NOUN
wh246q21940	7	15	proteins	protein	NOUN
wh246q21940	7	16	in	in	ADP
wh246q21940	7	17	a	a	DET
wh246q21940	7	18	well	well	ADV
wh246q21940	7	19	-	-	PUNCT
wh246q21940	7	20	established	establish	VERB
wh246q21940	7	21	phenomenon	phenomenon	NOUN
wh246q21940	7	22	termed	term	VERB
wh246q21940	7	23	alloreactivity	alloreactivity	NOUN
wh246q21940	7	24	,	,	PUNCT
wh246q21940	7	25	as	as	SCONJ
wh246q21940	7	26	evidenced	evidence	VERB
wh246q21940	7	27	by	by	ADP
wh246q21940	7	28	the	the	DET
wh246q21940	7	29	rejection	rejection	NOUN
wh246q21940	7	30	of	of	ADP
wh246q21940	7	31	transplanted	transplant	VERB
wh246q21940	7	32	organs	organ	NOUN
wh246q21940	7	33	and	and	CCONJ
wh246q21940	7	34	graft	graft	NOUN
wh246q21940	7	35	-	-	PUNCT
wh246q21940	7	36	versus	versus	ADP
wh246q21940	7	37	-	-	PUNCT
wh246q21940	7	38	host	host	NOUN
wh246q21940	7	39	disease	disease	NOUN
wh246q21940	7	40	(	(	PUNCT
wh246q21940	7	41	gvhd).t	gvhd).t	NOUN
wh246q21940	7	42	-	-	PUNCT
wh246q21940	7	43	cell	cell	NOUN
wh246q21940	7	44	receptor	receptor	NOUN
wh246q21940	7	45	(	(	PUNCT
wh246q21940	7	46	tcr	tcr	PROPN
wh246q21940	7	47	)	)	PUNCT
wh246q21940	7	48	allorecognition	allorecognition	NOUN
wh246q21940	7	49	is	be	AUX
wh246q21940	7	50	often	often	ADV
wh246q21940	7	51	believed	believe	VERB
wh246q21940	7	52	to	to	PART
wh246q21940	7	53	proceed	proceed	VERB
wh246q21940	7	54	with	with	ADP
wh246q21940	7	55	limited	limited	ADJ
wh246q21940	7	56	specificity	specificity	NOUN
wh246q21940	7	57	,	,	PUNCT
wh246q21940	7	58	owing	owe	VERB
wh246q21940	7	59	to	to	ADP
wh246q21940	7	60	either	either	CCONJ
wh246q21940	7	61	a	a	DET
wh246q21940	7	62	tcr	tcr	NOUN
wh246q21940	7	63	focus	focus	NOUN
wh246q21940	7	64	on	on	ADP
wh246q21940	7	65	the	the	DET
wh246q21940	7	66	exposed	expose	VERB
wh246q21940	7	67	polymorphic	polymorphic	ADJ
wh246q21940	7	68	residues	residue	NOUN
wh246q21940	7	69	on	on	ADP
wh246q21940	7	70	the	the	DET
wh246q21940	7	71	non	non	NOUN
wh246q21940	7	72	-	-	NOUN
wh246q21940	7	73	self	self	NOUN
wh246q21940	7	74	mhc	mhc	NOUN
wh246q21940	7	75	(	(	PUNCT
wh246q21940	7	76	mhc	mhc	PROPN
wh246q21940	7	77	-	-	PUNCT
wh246q21940	7	78	centric	centric	NOUN
wh246q21940	7	79	)	)	PUNCT
wh246q21940	7	80	or	or	CCONJ
wh246q21940	7	81	the	the	DET
wh246q21940	7	82	degenerate	degenerate	ADJ
wh246q21940	7	83	recognition	recognition	NOUN
wh246q21940	7	84	of	of	ADP
wh246q21940	7	85	allopeptides	allopeptide	NOUN
wh246q21940	7	86	(	(	PUNCT
wh246q21940	7	87	peptide	peptide	NOUN
wh246q21940	7	88	-	-	PUNCT
wh246q21940	7	89	centric	centric	NOUN
wh246q21940	7	90	)	)	PUNCT
wh246q21940	8	1	[	[	X
wh246q21940	8	2	2	2	NUM
wh246q21940	8	3	]	]	PUNCT
wh246q21940	8	4	.	.	PUNCT
wh246q21940	9	1	for	for	ADP
wh246q21940	9	2	instance	instance	NOUN
wh246q21940	9	3	,	,	PUNCT
wh246q21940	9	4	the	the	DET
wh246q21940	9	5	precursor	precursor	NOUN
wh246q21940	9	6	frequency	frequency	NOUN
wh246q21940	9	7	for	for	ADP
wh246q21940	9	8	alloreactive	alloreactive	ADJ
wh246q21940	9	9	t	t	NOUN
wh246q21940	9	10	cells	cell	NOUN
wh246q21940	9	11	is	be	AUX
wh246q21940	9	12	100	100	NUM
wh246q21940	9	13	-	-	ADJ
wh246q21940	9	14	fold	fold	NOUN
wh246q21940	9	15	to	to	ADP
wh246q21940	9	16	1000	1000	NUM
wh246q21940	9	17	-	-	ADJ
wh246q21940	9	18	fold	fold	VERB
wh246q21940	9	19	higher	high	ADJ
wh246q21940	9	20	than	than	ADP
wh246q21940	9	21	that	that	PRON
wh246q21940	9	22	of	of	ADP
wh246q21940	9	23	convention	convention	NOUN
wh246q21940	9	24	t	t	NOUN
wh246q21940	9	25	cells	cell	NOUN
wh246q21940	9	26	that	that	PRON
wh246q21940	9	27	are	be	AUX
wh246q21940	9	28	specific	specific	ADJ
wh246q21940	9	29	for	for	ADP
wh246q21940	9	30	one	one	NUM
wh246q21940	9	31	foreign	foreign	ADJ
wh246q21940	9	32	-	-	PUNCT
wh246q21940	9	33	peptide	peptide	NOUN
wh246q21940	9	34	-	-	PUNCT
wh246q21940	9	35	self	self	NOUN
wh246q21940	9	36	mhc	mhc	NOUN
wh246q21940	9	37	complex	complex	NOUN
wh246q21940	10	1	[	[	X
wh246q21940	10	2	3	3	NUM
wh246q21940	10	3	]	]	PUNCT
wh246q21940	10	4	.	.	PUNCT
wh246q21940	11	1	the	the	DET
wh246q21940	11	2	large	large	ADJ
wh246q21940	11	3	difference	difference	NOUN
wh246q21940	11	4	in	in	ADP
wh246q21940	11	5	precursor	precursor	PROPN
wh246q21940	11	6	frequency	frequency	PROPN
wh246q21940	11	7	suggested	suggest	VERB
wh246q21940	11	8	nonspecific	nonspecific	ADJ
wh246q21940	11	9	allorecognition	allorecognition	NOUN
wh246q21940	11	10	.	.	PUNCT
wh246q21940	12	1	surprisingly	surprisingly	ADV
wh246q21940	12	2	however	however	ADV
wh246q21940	12	3	,	,	PUNCT
wh246q21940	12	4	alloreactive	alloreactive	ADJ
wh246q21940	12	5	t	t	PROPN
wh246q21940	12	6	cells	cell	NOUN
wh246q21940	12	7	can	can	AUX
wh246q21940	12	8	achieve	achieve	VERB
wh246q21940	12	9	high	high	ADJ
wh246q21940	12	10	peptide	peptide	NOUN
wh246q21940	12	11	and	and	CCONJ
wh246q21940	12	12	mhc	mhc	ADJ
wh246q21940	12	13	specificity	specificity	NOUN
wh246q21940	12	14	[	[	X
wh246q21940	12	15	4	4	NUM
wh246q21940	12	16	]	]	PUNCT
wh246q21940	12	17	.	.	PUNCT
wh246q21940	13	1	although	although	SCONJ
wh246q21940	13	2	the	the	DET
wh246q21940	13	3	underlying	underlying	ADJ
wh246q21940	13	4	molecular	molecular	ADJ
wh246q21940	13	5	mechanisms	mechanism	NOUN
wh246q21940	13	6	remain	remain	VERB
wh246q21940	13	7	elusive	elusive	ADJ
wh246q21940	13	8	,	,	PUNCT
wh246q21940	13	9	people	people	NOUN
wh246q21940	13	10	are	be	AUX
wh246q21940	13	11	interested	interested	ADJ
wh246q21940	13	12	in	in	ADP
wh246q21940	13	13	the	the	DET
wh246q21940	13	14	use	use	NOUN
wh246q21940	13	15	of	of	ADP
wh246q21940	13	16	such	such	ADJ
wh246q21940	13	17	highly	highly	ADV
wh246q21940	13	18	specific	specific	ADJ
wh246q21940	13	19	alloreactive	alloreactive	ADJ
wh246q21940	13	20	tcrs	tcrs	NOUN
wh246q21940	13	21	in	in	ADP
wh246q21940	13	22	cancer	cancer	NOUN
wh246q21940	13	23	immunotherapy	immunotherapy	NOUN
wh246q21940	13	24	.	.	PUNCT
wh246q21940	14	1	in	in	ADP
wh246q21940	14	2	this	this	DET
wh246q21940	14	3	dissertation	dissertation	NOUN
wh246q21940	14	4	,	,	PUNCT
wh246q21940	14	5	we	we	PRON
wh246q21940	14	6	mainly	mainly	ADV
wh246q21940	14	7	discuss	discuss	VERB
wh246q21940	14	8	how	how	SCONJ
wh246q21940	14	9	an	an	DET
wh246q21940	14	10	alloreactive	alloreactive	ADJ
wh246q21940	14	11	tcr	tcr	PROPN
wh246q21940	14	12	achieves	achieve	VERB
wh246q21940	14	13	both	both	PRON
wh246q21940	14	14	peptide	peptide	NOUN
wh246q21940	14	15	and	and	CCONJ
wh246q21940	14	16	mhc	mhc	ADJ
wh246q21940	14	17	specificity	specificity	NOUN
wh246q21940	14	18	.	.	PUNCT
wh246q21940	15	1	in	in	ADP
wh246q21940	15	2	contrast	contrast	NOUN
wh246q21940	15	3	with	with	ADP
wh246q21940	15	4	current	current	ADJ
wh246q21940	15	5	theories	theory	NOUN
wh246q21940	15	6	of	of	ADP
wh246q21940	15	7	alloreactivity	alloreactivity	NOUN
wh246q21940	15	8	(	(	PUNCT
wh246q21940	15	9	mhc	mhc	NOUN
wh246q21940	15	10	-	-	PUNCT
wh246q21940	15	11	centric	centric	ADJ
wh246q21940	15	12	or	or	CCONJ
wh246q21940	15	13	peptide	peptide	NOUN
wh246q21940	15	14	-	-	PUNCT
wh246q21940	15	15	centric	centric	NOUN
wh246q21940	15	16	)	)	PUNCT
wh246q21940	15	17	,	,	PUNCT
wh246q21940	15	18	our	our	PRON
wh246q21940	15	19	structural	structural	ADJ
wh246q21940	15	20	and	and	CCONJ
wh246q21940	15	21	biophysical	biophysical	ADJ
wh246q21940	15	22	data	datum	NOUN
wh246q21940	15	23	suggests	suggest	VERB
wh246q21940	15	24	that	that	SCONJ
wh246q21940	15	25	high	high	ADJ
wh246q21940	15	26	specific	specific	ADJ
wh246q21940	15	27	allorecognition	allorecognition	NOUN
wh246q21940	15	28	is	be	AUX
wh246q21940	15	29	critically	critically	ADV
wh246q21940	15	30	depend	depend	VERB
wh246q21940	15	31	on	on	ADP
wh246q21940	15	32	the	the	DET
wh246q21940	15	33	unique	unique	ADJ
wh246q21940	15	34	features	feature	NOUN
wh246q21940	15	35	of	of	ADP
wh246q21940	15	36	allogeneic	allogeneic	ADJ
wh246q21940	15	37	mhc	mhc	NOUN
wh246q21940	15	38	and	and	CCONJ
wh246q21940	15	39	the	the	DET
wh246q21940	15	40	antigen	antigen	NOUN
wh246q21940	15	41	peptide	peptide	NOUN
wh246q21940	15	42	,	,	PUNCT
wh246q21940	15	43	relatively	relatively	ADV
wh246q21940	15	44	.	.	PUNCT
wh246q21940	16	1	more	more	ADV
wh246q21940	16	2	importantly	importantly	ADV
wh246q21940	16	3	,	,	PUNCT
wh246q21940	16	4	our	our	PRON
wh246q21940	16	5	findings	finding	NOUN
wh246q21940	16	6	emphasize	emphasize	VERB
wh246q21940	16	7	that	that	SCONJ
wh246q21940	16	8	the	the	DET
wh246q21940	16	9	peptide	peptide	NOUN
wh246q21940	16	10	features	feature	VERB
wh246q21940	16	11	working	work	VERB
wh246q21940	16	12	together	together	ADV
wh246q21940	16	13	with	with	ADP
wh246q21940	16	14	the	the	DET
wh246q21940	16	15	distinctive	distinctive	ADJ
wh246q21940	16	16	surface	surface	NOUN
wh246q21940	16	17	chemistry	chemistry	NOUN
wh246q21940	16	18	of	of	ADP
wh246q21940	16	19	allogeneic	allogeneic	PROPN
wh246q21940	16	20	mhc	mhc	PROPN
wh246q21940	16	21	,	,	PUNCT
wh246q21940	16	22	can	can	AUX
wh246q21940	16	23	direct	direct	VERB
wh246q21940	16	24	the	the	DET
wh246q21940	16	25	specificity	specificity	NOUN
wh246q21940	16	26	of	of	ADP
wh246q21940	16	27	allorecognition	allorecognition	NOUN
wh246q21940	16	28	.	.	PUNCT
wh246q21940	17	1	our	our	PRON
wh246q21940	17	2	results	result	NOUN
wh246q21940	17	3	broaden	broaden	VERB
wh246q21940	17	4	the	the	DET
wh246q21940	17	5	understanding	understanding	NOUN
wh246q21940	17	6	of	of	ADP
wh246q21940	17	7	the	the	DET
wh246q21940	17	8	specificity	specificity	NOUN
wh246q21940	17	9	of	of	ADP
wh246q21940	17	10	allorecognition	allorecognition	NOUN
wh246q21940	17	11	and	and	CCONJ
wh246q21940	17	12	provide	provide	VERB
wh246q21940	17	13	insight	insight	NOUN
wh246q21940	17	14	into	into	ADP
wh246q21940	17	15	the	the	DET
wh246q21940	17	16	use	use	NOUN
wh246q21940	17	17	of	of	ADP
wh246q21940	17	18	allospecific	allospecific	ADJ
wh246q21940	17	19	tcrs	tcrs	NOUN
wh246q21940	17	20	in	in	ADP
wh246q21940	17	21	immunotherapy	immunotherapy	NOUN
wh246q21940	17	22	.	.	PUNCT