id	sid	tid	token	lemma	pos
vt150g38r2n	1	1	the	the	DET
vt150g38r2n	1	2	metastasis	metastasis	NOUN
vt150g38r2n	1	3	of	of	ADP
vt150g38r2n	1	4	cancer	cancer	NOUN
vt150g38r2n	1	5	cells	cell	NOUN
vt150g38r2n	1	6	to	to	ADP
vt150g38r2n	1	7	distant	distant	ADJ
vt150g38r2n	1	8	sites	site	NOUN
vt150g38r2n	1	9	accounts	account	VERB
vt150g38r2n	1	10	for	for	ADP
vt150g38r2n	1	11	over	over	ADP
vt150g38r2n	1	12	90	90	NUM
vt150g38r2n	1	13	%	%	NOUN
vt150g38r2n	1	14	of	of	ADP
vt150g38r2n	1	15	cancer	cancer	NOUN
vt150g38r2n	1	16	related	relate	VERB
vt150g38r2n	1	17	deaths	death	NOUN
vt150g38r2n	1	18	.	.	PUNCT
vt150g38r2n	2	1	in	in	ADP
vt150g38r2n	2	2	order	order	NOUN
vt150g38r2n	2	3	to	to	PART
vt150g38r2n	2	4	metastasize	metastasize	VERB
vt150g38r2n	2	5	,	,	PUNCT
vt150g38r2n	2	6	cancer	cancer	NOUN
vt150g38r2n	2	7	cells	cell	NOUN
vt150g38r2n	2	8	must	must	AUX
vt150g38r2n	2	9	be	be	AUX
vt150g38r2n	2	10	able	able	ADJ
vt150g38r2n	2	11	to	to	PART
vt150g38r2n	2	12	survive	survive	VERB
vt150g38r2n	2	13	during	during	ADP
vt150g38r2n	2	14	extracellular	extracellular	ADJ
vt150g38r2n	2	15	matrix	matrix	NOUN
vt150g38r2n	2	16	(	(	PUNCT
vt150g38r2n	2	17	ecm	ecm	PROPN
vt150g38r2n	2	18	)	)	PUNCT
vt150g38r2n	2	19	detachment	detachment	NOUN
vt150g38r2n	2	20	,	,	PUNCT
vt150g38r2n	2	21	namely	namely	ADV
vt150g38r2n	2	22	by	by	ADP
vt150g38r2n	2	23	blocking	block	VERB
vt150g38r2n	2	24	anoikis	anoiki	NOUN
vt150g38r2n	2	25	(	(	PUNCT
vt150g38r2n	2	26	a	a	DET
vt150g38r2n	2	27	caspase	caspase	NOUN
vt150g38r2n	2	28	-	-	PUNCT
vt150g38r2n	2	29	dependent	dependent	ADJ
vt150g38r2n	2	30	cell	cell	NOUN
vt150g38r2n	2	31	death	death	NOUN
vt150g38r2n	2	32	)	)	PUNCT
vt150g38r2n	2	33	and	and	CCONJ
vt150g38r2n	2	34	restoring	restore	VERB
vt150g38r2n	2	35	metabolic	metabolic	ADJ
vt150g38r2n	2	36	deficiencies	deficiency	NOUN
vt150g38r2n	2	37	.	.	PUNCT
vt150g38r2n	3	1	such	such	ADJ
vt150g38r2n	3	2	barriers	barrier	NOUN
vt150g38r2n	3	3	during	during	ADP
vt150g38r2n	3	4	tumorigenesis	tumorigenesis	NOUN
vt150g38r2n	3	5	are	be	AUX
vt150g38r2n	3	6	abrogated	abrogate	VERB
vt150g38r2n	3	7	through	through	ADP
vt150g38r2n	3	8	activation	activation	NOUN
vt150g38r2n	3	9	of	of	ADP
vt150g38r2n	3	10	oncogenic	oncogenic	ADJ
vt150g38r2n	3	11	signaling	signaling	NOUN
vt150g38r2n	3	12	,	,	PUNCT
vt150g38r2n	3	13	and/or	and/or	CCONJ
vt150g38r2n	3	14	inhibition	inhibition	NOUN
vt150g38r2n	3	15	of	of	ADP
vt150g38r2n	3	16	tumor	tumor	NOUN
vt150g38r2n	3	17	suppressors	suppressor	NOUN
vt150g38r2n	3	18	.	.	PUNCT
vt150g38r2n	4	1	furthermore	furthermore	ADV
vt150g38r2n	4	2	,	,	PUNCT
vt150g38r2n	4	3	the	the	DET
vt150g38r2n	4	4	tumor	tumor	NOUN
vt150g38r2n	4	5	microenvironment	microenvironment	NOUN
vt150g38r2n	4	6	(	(	PUNCT
vt150g38r2n	4	7	tme	tme	PROPN
vt150g38r2n	4	8	)	)	PUNCT
vt150g38r2n	4	9	,	,	PUNCT
vt150g38r2n	4	10	comprised	comprise	VERB
vt150g38r2n	4	11	of	of	ADP
vt150g38r2n	4	12	a	a	DET
vt150g38r2n	4	13	heterogeneous	heterogeneous	ADJ
vt150g38r2n	4	14	population	population	NOUN
vt150g38r2n	4	15	of	of	ADP
vt150g38r2n	4	16	transformed	transformed	PROPN
vt150g38r2n	4	17	and	and	CCONJ
vt150g38r2n	4	18	non	non	ADJ
vt150g38r2n	4	19	-	-	ADJ
vt150g38r2n	4	20	transformed	transformed	ADJ
vt150g38r2n	4	21	cells	cell	NOUN
vt150g38r2n	4	22	,	,	PUNCT
vt150g38r2n	4	23	plays	play	VERB
vt150g38r2n	4	24	a	a	DET
vt150g38r2n	4	25	crucial	crucial	ADJ
vt150g38r2n	4	26	role	role	NOUN
vt150g38r2n	4	27	in	in	ADP
vt150g38r2n	4	28	cancer	cancer	NOUN
vt150g38r2n	4	29	growth	growth	NOUN
vt150g38r2n	4	30	.	.	PUNCT
vt150g38r2n	5	1	studies	study	NOUN
vt150g38r2n	5	2	have	have	AUX
vt150g38r2n	5	3	shown	show	VERB
vt150g38r2n	5	4	that	that	SCONJ
vt150g38r2n	5	5	there	there	PRON
vt150g38r2n	5	6	is	be	VERB
vt150g38r2n	5	7	continuous	continuous	ADJ
vt150g38r2n	5	8	bidirectional	bidirectional	ADJ
vt150g38r2n	5	9	communication	communication	NOUN
vt150g38r2n	5	10	between	between	ADP
vt150g38r2n	5	11	cancer	cancer	NOUN
vt150g38r2n	5	12	cells	cell	NOUN
vt150g38r2n	5	13	and	and	CCONJ
vt150g38r2n	5	14	the	the	DET
vt150g38r2n	5	15	different	different	ADJ
vt150g38r2n	5	16	cell	cell	NOUN
vt150g38r2n	5	17	populations	population	NOUN
vt150g38r2n	5	18	within	within	ADP
vt150g38r2n	5	19	the	the	DET
vt150g38r2n	5	20	tme	tme	NOUN
vt150g38r2n	5	21	.	.	PUNCT
vt150g38r2n	6	1	this	this	DET
vt150g38r2n	6	2	communication	communication	NOUN
vt150g38r2n	6	3	can	can	AUX
vt150g38r2n	6	4	either	either	CCONJ
vt150g38r2n	6	5	work	work	VERB
vt150g38r2n	6	6	to	to	PART
vt150g38r2n	6	7	promote	promote	VERB
vt150g38r2n	6	8	tumor	tumor	NOUN
vt150g38r2n	6	9	growth	growth	NOUN
vt150g38r2n	6	10	,	,	PUNCT
vt150g38r2n	6	11	as	as	SCONJ
vt150g38r2n	6	12	seen	see	VERB
vt150g38r2n	6	13	with	with	ADP
vt150g38r2n	6	14	carcinoma	carcinoma	NOUN
vt150g38r2n	6	15	associated	associate	VERB
vt150g38r2n	6	16	fibroblasts	fibroblast	NOUN
vt150g38r2n	6	17	(	(	PUNCT
vt150g38r2n	6	18	cafs	cafs	PROPN
vt150g38r2n	6	19	)	)	PUNCT
vt150g38r2n	6	20	,	,	PUNCT
vt150g38r2n	6	21	or	or	CCONJ
vt150g38r2n	6	22	inhibit	inhibit	VERB
vt150g38r2n	6	23	tumor	tumor	NOUN
vt150g38r2n	6	24	growth	growth	NOUN
vt150g38r2n	6	25	,	,	PUNCT
vt150g38r2n	6	26	as	as	SCONJ
vt150g38r2n	6	27	observed	observe	VERB
vt150g38r2n	6	28	with	with	ADP
vt150g38r2n	6	29	tumor	tumor	NOUN
vt150g38r2n	6	30	infiltrating	infiltrate	VERB
vt150g38r2n	6	31	lymphoid	lymphoid	NOUN
vt150g38r2n	6	32	cells	cell	NOUN
vt150g38r2n	6	33	.	.	PUNCT
vt150g38r2n	7	1	in	in	ADP
vt150g38r2n	7	2	this	this	DET
vt150g38r2n	7	3	study	study	NOUN
vt150g38r2n	7	4	,	,	PUNCT
vt150g38r2n	7	5	we	we	PRON
vt150g38r2n	7	6	investigate	investigate	VERB
vt150g38r2n	7	7	the	the	DET
vt150g38r2n	7	8	context	context	NOUN
vt150g38r2n	7	9	dependent	dependent	ADJ
vt150g38r2n	7	10	role	role	NOUN
vt150g38r2n	7	11	of	of	ADP
vt150g38r2n	7	12	cellular	cellular	ADJ
vt150g38r2n	7	13	flice	flice	NOUN
vt150g38r2n	7	14	-	-	PUNCT
vt150g38r2n	7	15	like	like	ADJ
vt150g38r2n	7	16	inhibitory	inhibitory	ADJ
vt150g38r2n	7	17	protein	protein	NOUN
vt150g38r2n	7	18	(	(	PUNCT
vt150g38r2n	7	19	c	c	X
vt150g38r2n	7	20	-	-	PUNCT
vt150g38r2n	7	21	flip	flip	NOUN
vt150g38r2n	7	22	)	)	PUNCT
vt150g38r2n	7	23	,	,	PUNCT
vt150g38r2n	7	24	a	a	DET
vt150g38r2n	7	25	protein	protein	NOUN
vt150g38r2n	7	26	well	well	ADV
vt150g38r2n	7	27	known	know	VERB
vt150g38r2n	7	28	for	for	ADP
vt150g38r2n	7	29	antagonizing	antagonize	VERB
vt150g38r2n	7	30	receptor	receptor	NOUN
vt150g38r2n	7	31	-	-	PUNCT
vt150g38r2n	7	32	mediated	mediate	VERB
vt150g38r2n	7	33	apoptosis	apoptosis	NOUN
vt150g38r2n	7	34	,	,	PUNCT
vt150g38r2n	7	35	in	in	ADP
vt150g38r2n	7	36	modulating	modulate	VERB
vt150g38r2n	7	37	the	the	DET
vt150g38r2n	7	38	survival	survival	NOUN
vt150g38r2n	7	39	of	of	ADP
vt150g38r2n	7	40	cancer	cancer	NOUN
vt150g38r2n	7	41	cells	cell	NOUN
vt150g38r2n	7	42	.	.	PUNCT
vt150g38r2n	8	1	we	we	PRON
vt150g38r2n	8	2	demonstrate	demonstrate	VERB
vt150g38r2n	8	3	that	that	SCONJ
vt150g38r2n	8	4	normal	normal	ADJ
vt150g38r2n	8	5	mammary	mammary	ADJ
vt150g38r2n	8	6	fibroblasts	fibroblast	NOUN
vt150g38r2n	8	7	(	(	PUNCT
vt150g38r2n	8	8	fibroblasts	fibroblast	NOUN
vt150g38r2n	8	9	isolated	isolate	VERB
vt150g38r2n	8	10	from	from	ADP
vt150g38r2n	8	11	normal	normal	ADJ
vt150g38r2n	8	12	breast	breast	NOUN
vt150g38r2n	8	13	tissue	tissue	NOUN
vt150g38r2n	8	14	)	)	PUNCT
vt150g38r2n	8	15	secrete	secrete	NOUN
vt150g38r2n	8	16	soluble	soluble	ADJ
vt150g38r2n	8	17	factors	factor	NOUN
vt150g38r2n	8	18	that	that	PRON
vt150g38r2n	8	19	induce	induce	VERB
vt150g38r2n	8	20	caspase	caspase	NOUN
vt150g38r2n	8	21	-	-	PUNCT
vt150g38r2n	8	22	mediated	mediate	VERB
vt150g38r2n	8	23	cell	cell	NOUN
vt150g38r2n	8	24	death	death	NOUN
vt150g38r2n	8	25	in	in	ADP
vt150g38r2n	8	26	a	a	DET
vt150g38r2n	8	27	variety	variety	NOUN
vt150g38r2n	8	28	of	of	ADP
vt150g38r2n	8	29	cancer	cancer	NOUN
vt150g38r2n	8	30	cell	cell	NOUN
vt150g38r2n	8	31	lines	line	NOUN
vt150g38r2n	8	32	.	.	PUNCT
vt150g38r2n	9	1	we	we	PRON
vt150g38r2n	9	2	observed	observe	VERB
vt150g38r2n	9	3	a	a	DET
vt150g38r2n	9	4	substantive	substantive	ADJ
vt150g38r2n	9	5	increase	increase	NOUN
vt150g38r2n	9	6	in	in	ADP
vt150g38r2n	9	7	the	the	DET
vt150g38r2n	9	8	cleavage	cleavage	NOUN
vt150g38r2n	9	9	of	of	ADP
vt150g38r2n	9	10	caspase	caspase	NOUN
vt150g38r2n	9	11	8	8	NUM
vt150g38r2n	9	12	that	that	PRON
vt150g38r2n	9	13	is	be	AUX
vt150g38r2n	9	14	mediated	mediate	VERB
vt150g38r2n	9	15	by	by	ADP
vt150g38r2n	9	16	the	the	DET
vt150g38r2n	9	17	modulation	modulation	NOUN
vt150g38r2n	9	18	of	of	ADP
vt150g38r2n	9	19	c	c	NOUN
vt150g38r2n	9	20	-	-	PUNCT
vt150g38r2n	9	21	flip	flip	ADJ
vt150g38r2n	9	22	levels	level	NOUN
vt150g38r2n	9	23	by	by	ADP
vt150g38r2n	9	24	stress	stress	NOUN
vt150g38r2n	9	25	-	-	PUNCT
vt150g38r2n	9	26	activated	activate	VERB
vt150g38r2n	9	27	mapk	mapk	NOUN
vt150g38r2n	9	28	signaling	signaling	NOUN
vt150g38r2n	9	29	.	.	PUNCT
vt150g38r2n	10	1	furthermore	furthermore	ADV
vt150g38r2n	10	2	,	,	PUNCT
vt150g38r2n	10	3	our	our	PRON
vt150g38r2n	10	4	investigation	investigation	NOUN
vt150g38r2n	10	5	has	have	AUX
vt150g38r2n	10	6	revealed	reveal	VERB
vt150g38r2n	10	7	a	a	DET
vt150g38r2n	10	8	surprising	surprising	ADJ
vt150g38r2n	10	9	role	role	NOUN
vt150g38r2n	10	10	of	of	ADP
vt150g38r2n	10	11	c	c	NOUN
vt150g38r2n	10	12	-	-	PUNCT
vt150g38r2n	10	13	flip	flip	NOUN
vt150g38r2n	10	14	in	in	ADP
vt150g38r2n	10	15	antagonizing	antagonize	VERB
vt150g38r2n	10	16	the	the	DET
vt150g38r2n	10	17	viability	viability	NOUN
vt150g38r2n	10	18	of	of	ADP
vt150g38r2n	10	19	ecm	ecm	PROPN
vt150g38r2n	10	20	-	-	PUNCT
vt150g38r2n	10	21	detached	detach	VERB
vt150g38r2n	10	22	cancer	cancer	NOUN
vt150g38r2n	10	23	cells	cell	NOUN
vt150g38r2n	10	24	.	.	PUNCT
vt150g38r2n	11	1	additionally	additionally	ADV
vt150g38r2n	11	2	,	,	PUNCT
vt150g38r2n	11	3	we	we	PRON
vt150g38r2n	11	4	demonstrated	demonstrate	VERB
vt150g38r2n	11	5	that	that	SCONJ
vt150g38r2n	11	6	signaling	signal	VERB
vt150g38r2n	11	7	emanating	emanate	VERB
vt150g38r2n	11	8	from	from	ADP
vt150g38r2n	11	9	oncogenic	oncogenic	ADJ
vt150g38r2n	11	10	growth	growth	NOUN
vt150g38r2n	11	11	factor	factor	NOUN
vt150g38r2n	11	12	receptors	receptor	NOUN
vt150g38r2n	11	13	results	result	NOUN
vt150g38r2n	11	14	in	in	ADP
vt150g38r2n	11	15	the	the	DET
vt150g38r2n	11	16	downregulation	downregulation	NOUN
vt150g38r2n	11	17	of	of	ADP
vt150g38r2n	11	18	c	c	X
vt150g38r2n	11	19	-	-	PUNCT
vt150g38r2n	11	20	flip	flip	ADJ
vt150g38r2n	11	21	expression	expression	NOUN
vt150g38r2n	11	22	providing	provide	VERB
vt150g38r2n	11	23	additional	additional	ADJ
vt150g38r2n	11	24	evidence	evidence	NOUN
vt150g38r2n	11	25	that	that	SCONJ
vt150g38r2n	11	26	cancer	cancer	NOUN
vt150g38r2n	11	27	cells	cell	NOUN
vt150g38r2n	11	28	may	may	AUX
vt150g38r2n	11	29	benefit	benefit	VERB
vt150g38r2n	11	30	from	from	ADP
vt150g38r2n	11	31	diminished	diminished	ADJ
vt150g38r2n	11	32	flip	flip	ADJ
vt150g38r2n	11	33	levels	level	NOUN
vt150g38r2n	11	34	.	.	PUNCT
vt150g38r2n	12	1	interestingly	interestingly	ADV
vt150g38r2n	12	2	,	,	PUNCT
vt150g38r2n	12	3	this	this	DET
vt150g38r2n	12	4	repression	repression	NOUN
vt150g38r2n	12	5	of	of	ADP
vt150g38r2n	12	6	c	c	X
vt150g38r2n	12	7	-	-	PUNCT
vt150g38r2n	12	8	flip	flip	ADJ
vt150g38r2n	12	9	expression	expression	NOUN
vt150g38r2n	12	10	by	by	ADP
vt150g38r2n	12	11	activated	activate	VERB
vt150g38r2n	12	12	oncogenes	oncogene	NOUN
vt150g38r2n	12	13	is	be	AUX
vt150g38r2n	12	14	a	a	DET
vt150g38r2n	12	15	consequence	consequence	NOUN
vt150g38r2n	12	16	of	of	ADP
vt150g38r2n	12	17	pi(3)k	pi(3)k	PROPN
vt150g38r2n	12	18	signaling	signal	VERB
vt150g38r2n	12	19	.	.	PUNCT
vt150g38r2n	13	1	in	in	ADP
vt150g38r2n	13	2	addition	addition	NOUN
vt150g38r2n	13	3	,	,	PUNCT
vt150g38r2n	13	4	our	our	PRON
vt150g38r2n	13	5	data	datum	NOUN
vt150g38r2n	13	6	reveal	reveal	VERB
vt150g38r2n	13	7	that	that	DET
vt150g38r2n	13	8	elimination	elimination	NOUN
vt150g38r2n	13	9	of	of	ADP
vt150g38r2n	13	10	c	c	X
vt150g38r2n	13	11	-	-	PUNCT
vt150g38r2n	13	12	flip	flip	NOUN
vt150g38r2n	13	13	promotes	promote	VERB
vt150g38r2n	13	14	the	the	DET
vt150g38r2n	13	15	survival	survival	NOUN
vt150g38r2n	13	16	of	of	ADP
vt150g38r2n	13	17	ecm	ecm	PROPN
vt150g38r2n	13	18	-	-	PUNCT
vt150g38r2n	13	19	detached	detach	VERB
vt150g38r2n	13	20	cells	cell	NOUN
vt150g38r2n	13	21	and	and	CCONJ
vt150g38r2n	13	22	that	that	SCONJ
vt150g38r2n	13	23	c	c	NOUN
vt150g38r2n	13	24	-	-	PUNCT
vt150g38r2n	13	25	flip	flip	ADJ
vt150g38r2n	13	26	overexpression	overexpression	NOUN
vt150g38r2n	13	27	in	in	ADP
vt150g38r2n	13	28	cancer	cancer	NOUN
vt150g38r2n	13	29	cells	cell	NOUN
vt150g38r2n	13	30	restricts	restrict	VERB
vt150g38r2n	13	31	the	the	DET
vt150g38r2n	13	32	viability	viability	NOUN
vt150g38r2n	13	33	of	of	ADP
vt150g38r2n	13	34	cancer	cancer	NOUN
vt150g38r2n	13	35	cells	cell	NOUN
vt150g38r2n	13	36	grown	grow	VERB
vt150g38r2n	13	37	in	in	ADP
vt150g38r2n	13	38	anchorage	anchorage	NOUN
vt150g38r2n	13	39	-	-	PUNCT
vt150g38r2n	13	40	independent	independent	ADJ
vt150g38r2n	13	41	conditions	condition	NOUN
vt150g38r2n	13	42	.	.	PUNCT
vt150g38r2n	14	1	taken	take	VERB
vt150g38r2n	14	2	together	together	ADV
vt150g38r2n	14	3	,	,	PUNCT
vt150g38r2n	14	4	our	our	PRON
vt150g38r2n	14	5	study	study	NOUN
vt150g38r2n	14	6	reveals	reveal	VERB
vt150g38r2n	14	7	an	an	DET
vt150g38r2n	14	8	unexpected	unexpected	ADJ
vt150g38r2n	14	9	role	role	NOUN
vt150g38r2n	14	10	for	for	ADP
vt150g38r2n	14	11	c	c	X
vt150g38r2n	14	12	-	-	PUNCT
vt150g38r2n	14	13	flip	flip	NOUN
vt150g38r2n	14	14	in	in	ADP
vt150g38r2n	14	15	constraining	constrain	VERB
vt150g38r2n	14	16	the	the	DET
vt150g38r2n	14	17	viability	viability	NOUN
vt150g38r2n	14	18	of	of	ADP
vt150g38r2n	14	19	cancer	cancer	NOUN
vt150g38r2n	14	20	cells	cell	NOUN
vt150g38r2n	14	21	during	during	ADP
vt150g38r2n	14	22	ecm	ecm	NOUN
vt150g38r2n	14	23	-	-	NOUN
vt150g38r2n	14	24	detachment	detachment	NOUN
vt150g38r2n	14	25	and	and	CCONJ
vt150g38r2n	14	26	raises	raise	VERB
vt150g38r2n	14	27	the	the	DET
vt150g38r2n	14	28	idea	idea	NOUN
vt150g38r2n	14	29	that	that	SCONJ
vt150g38r2n	14	30	c	c	X
vt150g38r2n	14	31	-	-	PUNCT
vt150g38r2n	14	32	flip	flip	PROPN
vt150g38r2n	14	33	may	may	AUX
vt150g38r2n	14	34	have	have	AUX
vt150g38r2n	14	35	context	context	NOUN
vt150g38r2n	14	36	-	-	PUNCT
vt150g38r2n	14	37	dependent	dependent	ADJ
vt150g38r2n	14	38	proand	proand	PROPN
vt150g38r2n	14	39	anti	anti	ADJ
vt150g38r2n	14	40	-	-	ADJ
vt150g38r2n	14	41	cell	cell	ADJ
vt150g38r2n	14	42	death	death	NOUN
vt150g38r2n	14	43	roles	role	NOUN
vt150g38r2n	14	44	during	during	ADP
vt150g38r2n	14	45	tumorigenesis	tumorigenesis	NOUN
vt150g38r2n	14	46	.	.	PUNCT