id	sid	tid	token	lemma	pos
v979v122f32	1	1	in	in	ADP
v979v122f32	1	2	normal	normal	ADJ
v979v122f32	1	3	tissue	tissue	NOUN
v979v122f32	1	4	homeostasis	homeostasis	NOUN
v979v122f32	1	5	,	,	PUNCT
v979v122f32	1	6	bidirectional	bidirectional	ADJ
v979v122f32	1	7	communication	communication	NOUN
v979v122f32	1	8	between	between	ADP
v979v122f32	1	9	different	different	ADJ
v979v122f32	1	10	cell	cell	NOUN
v979v122f32	1	11	types	type	NOUN
v979v122f32	1	12	can	can	AUX
v979v122f32	1	13	shape	shape	VERB
v979v122f32	1	14	numerous	numerous	ADJ
v979v122f32	1	15	,	,	PUNCT
v979v122f32	1	16	biological	biological	ADJ
v979v122f32	1	17	outcomes	outcome	NOUN
v979v122f32	1	18	.	.	PUNCT
v979v122f32	2	1	within	within	ADP
v979v122f32	2	2	the	the	DET
v979v122f32	2	3	microenvironment	microenvironment	NOUN
v979v122f32	2	4	,	,	PUNCT
v979v122f32	2	5	there	there	PRON
v979v122f32	2	6	exist	exist	VERB
v979v122f32	2	7	many	many	ADJ
v979v122f32	2	8	cell	cell	NOUN
v979v122f32	2	9	types	type	NOUN
v979v122f32	2	10	including	include	VERB
v979v122f32	2	11	epithelial	epithelial	ADJ
v979v122f32	2	12	cells	cell	NOUN
v979v122f32	2	13	,	,	PUNCT
v979v122f32	2	14	tumor	tumor	NOUN
v979v122f32	2	15	cells	cell	NOUN
v979v122f32	2	16	,	,	PUNCT
v979v122f32	2	17	immune	immune	ADJ
v979v122f32	2	18	cells	cell	NOUN
v979v122f32	2	19	,	,	PUNCT
v979v122f32	2	20	and	and	CCONJ
v979v122f32	2	21	stromal	stromal	ADJ
v979v122f32	2	22	cells	cell	NOUN
v979v122f32	2	23	.	.	PUNCT
v979v122f32	3	1	one	one	NUM
v979v122f32	3	2	cell	cell	NOUN
v979v122f32	3	3	type	type	NOUN
v979v122f32	3	4	that	that	PRON
v979v122f32	3	5	is	be	AUX
v979v122f32	3	6	prevalent	prevalent	ADJ
v979v122f32	3	7	in	in	ADP
v979v122f32	3	8	tissues	tissue	NOUN
v979v122f32	3	9	surrounding	surround	VERB
v979v122f32	3	10	tumors	tumor	NOUN
v979v122f32	3	11	are	be	AUX
v979v122f32	3	12	fibroblasts	fibroblast	NOUN
v979v122f32	3	13	,	,	PUNCT
v979v122f32	3	14	which	which	PRON
v979v122f32	3	15	often	often	ADV
v979v122f32	3	16	undergo	undergo	VERB
v979v122f32	3	17	senescence	senescence	NOUN
v979v122f32	3	18	,	,	PUNCT
v979v122f32	3	19	transition	transition	NOUN
v979v122f32	3	20	in	in	ADP
v979v122f32	3	21	myofibroblasts	myofibroblast	NOUN
v979v122f32	3	22	,	,	PUNCT
v979v122f32	3	23	or	or	CCONJ
v979v122f32	3	24	carcinoma	carcinoma	NOUN
v979v122f32	3	25	associated	associate	VERB
v979v122f32	3	26	fibroblasts	fibroblast	NOUN
v979v122f32	3	27	(	(	PUNCT
v979v122f32	3	28	cafs	cafs	PROPN
v979v122f32	3	29	)	)	PUNCT
v979v122f32	3	30	and	and	CCONJ
v979v122f32	3	31	greatly	greatly	ADV
v979v122f32	3	32	influence	influence	NOUN
v979v122f32	3	33	shaping	shape	VERB
v979v122f32	3	34	the	the	DET
v979v122f32	3	35	composition	composition	NOUN
v979v122f32	3	36	of	of	ADP
v979v122f32	3	37	the	the	DET
v979v122f32	3	38	microenvironment	microenvironment	NOUN
v979v122f32	3	39	.	.	PUNCT
v979v122f32	4	1	fibroblasts	fibroblast	NOUN
v979v122f32	4	2	have	have	AUX
v979v122f32	4	3	been	be	AUX
v979v122f32	4	4	shown	show	VERB
v979v122f32	4	5	to	to	PART
v979v122f32	4	6	be	be	AUX
v979v122f32	4	7	prone	prone	ADJ
v979v122f32	4	8	to	to	PART
v979v122f32	4	9	undergo	undergo	VERB
v979v122f32	4	10	senescence	senescence	NOUN
v979v122f32	4	11	,	,	PUNCT
v979v122f32	4	12	exemplified	exemplify	VERB
v979v122f32	4	13	by	by	ADP
v979v122f32	4	14	an	an	DET
v979v122f32	4	15	irreversible	irreversible	ADJ
v979v122f32	4	16	cell	cell	NOUN
v979v122f32	4	17	cycle	cycle	NOUN
v979v122f32	4	18	arrest	arrest	NOUN
v979v122f32	4	19	in	in	ADP
v979v122f32	4	20	response	response	NOUN
v979v122f32	4	21	to	to	ADP
v979v122f32	4	22	a	a	DET
v979v122f32	4	23	variety	variety	NOUN
v979v122f32	4	24	of	of	ADP
v979v122f32	4	25	stimuli	stimulus	NOUN
v979v122f32	4	26	such	such	ADJ
v979v122f32	4	27	as	as	ADP
v979v122f32	4	28	bleomycin	bleomycin	PROPN
v979v122f32	4	29	(	(	PUNCT
v979v122f32	4	30	bis	bis	PROPN
v979v122f32	4	31	)	)	PUNCT
v979v122f32	4	32	or	or	CCONJ
v979v122f32	4	33	oncogene	oncogene	ADJ
v979v122f32	4	34	induced	induce	VERB
v979v122f32	4	35	senescence	senescence	NOUN
v979v122f32	4	36	(	(	PUNCT
v979v122f32	4	37	ois	ois	PROPN
v979v122f32	4	38	)	)	PUNCT
v979v122f32	4	39	.	.	PUNCT
v979v122f32	5	1	senescent	senescent	NOUN
v979v122f32	5	2	cells	cell	NOUN
v979v122f32	5	3	exhibit	exhibit	VERB
v979v122f32	5	4	alterations	alteration	NOUN
v979v122f32	5	5	in	in	ADP
v979v122f32	5	6	gene	gene	NOUN
v979v122f32	5	7	expression	expression	NOUN
v979v122f32	5	8	and	and	CCONJ
v979v122f32	5	9	are	be	AUX
v979v122f32	5	10	characterized	characterize	VERB
v979v122f32	5	11	by	by	ADP
v979v122f32	5	12	substantial	substantial	ADJ
v979v122f32	5	13	changes	change	NOUN
v979v122f32	5	14	in	in	ADP
v979v122f32	5	15	their	their	PRON
v979v122f32	5	16	secretome	secretome	NOUN
v979v122f32	5	17	;	;	PUNCT
v979v122f32	5	18	termed	term	VERB
v979v122f32	5	19	the	the	DET
v979v122f32	5	20	senescence	senescence	NOUN
v979v122f32	5	21	associated	associate	VERB
v979v122f32	5	22	secretory	secretory	NOUN
v979v122f32	5	23	phenotype	phenotype	NOUN
v979v122f32	5	24	(	(	PUNCT
v979v122f32	5	25	sasp	sasp	NOUN
v979v122f32	5	26	)	)	PUNCT
v979v122f32	5	27	.	.	PUNCT
v979v122f32	6	1	while	while	SCONJ
v979v122f32	6	2	the	the	DET
v979v122f32	6	3	role	role	NOUN
v979v122f32	6	4	of	of	ADP
v979v122f32	6	5	fibroblast	fibroblast	ADJ
v979v122f32	6	6	derived	derive	VERB
v979v122f32	6	7	sasp	sasp	NOUN
v979v122f32	6	8	factors	factor	NOUN
v979v122f32	6	9	on	on	ADP
v979v122f32	6	10	cancer	cancer	NOUN
v979v122f32	6	11	cells	cell	NOUN
v979v122f32	6	12	has	have	AUX
v979v122f32	6	13	been	be	AUX
v979v122f32	6	14	well	well	ADV
v979v122f32	6	15	studied	study	VERB
v979v122f32	6	16	,	,	PUNCT
v979v122f32	6	17	the	the	DET
v979v122f32	6	18	impact	impact	NOUN
v979v122f32	6	19	of	of	ADP
v979v122f32	6	20	these	these	DET
v979v122f32	6	21	factors	factor	NOUN
v979v122f32	6	22	on	on	ADP
v979v122f32	6	23	normal	normal	ADJ
v979v122f32	6	24	epithelial	epithelial	ADJ
v979v122f32	6	25	cells	cell	NOUN
v979v122f32	6	26	remains	remains	AUX
v979v122f32	6	27	poorly	poorly	ADV
v979v122f32	6	28	understood	understand	VERB
v979v122f32	6	29	.	.	PUNCT
v979v122f32	7	1	the	the	DET
v979v122f32	7	2	cell	cell	NOUN
v979v122f32	7	3	type	type	NOUN
v979v122f32	7	4	and	and	CCONJ
v979v122f32	7	5	senescence	senescence	NOUN
v979v122f32	7	6	inducer	inducer	NOUN
v979v122f32	7	7	specific	specific	ADJ
v979v122f32	7	8	effects	effect	NOUN
v979v122f32	7	9	can	can	AUX
v979v122f32	7	10	greatly	greatly	ADV
v979v122f32	7	11	influence	influence	VERB
v979v122f32	7	12	the	the	DET
v979v122f32	7	13	composition	composition	NOUN
v979v122f32	7	14	of	of	ADP
v979v122f32	7	15	the	the	DET
v979v122f32	7	16	sasp	sasp	NOUN
v979v122f32	7	17	,	,	PUNCT
v979v122f32	7	18	often	often	ADV
v979v122f32	7	19	comprised	comprise	VERB
v979v122f32	7	20	of	of	ADP
v979v122f32	7	21	pro	pro	ADJ
v979v122f32	7	22	-	-	ADJ
v979v122f32	7	23	inflammatory	inflammatory	ADJ
v979v122f32	7	24	factors	factor	NOUN
v979v122f32	7	25	.	.	PUNCT
v979v122f32	8	1	the	the	DET
v979v122f32	8	2	nature	nature	NOUN
v979v122f32	8	3	of	of	ADP
v979v122f32	8	4	the	the	DET
v979v122f32	8	5	secreted	secrete	VERB
v979v122f32	8	6	factors	factor	NOUN
v979v122f32	8	7	from	from	ADP
v979v122f32	8	8	senescent	senescent	NOUN
v979v122f32	8	9	cells	cell	NOUN
v979v122f32	8	10	can	can	AUX
v979v122f32	8	11	dictate	dictate	VERB
v979v122f32	8	12	whether	whether	SCONJ
v979v122f32	8	13	senescence	senescence	NOUN
v979v122f32	8	14	will	will	AUX
v979v122f32	8	15	function	function	VERB
v979v122f32	8	16	in	in	ADP
v979v122f32	8	17	a	a	DET
v979v122f32	8	18	tumor	tumor	NOUN
v979v122f32	8	19	suppressive	suppressive	NOUN
v979v122f32	8	20	or	or	CCONJ
v979v122f32	8	21	tumor	tumor	NOUN
v979v122f32	8	22	promoting	promote	VERB
v979v122f32	8	23	fashion	fashion	NOUN
v979v122f32	8	24	.	.	PUNCT
v979v122f32	9	1	our	our	PRON
v979v122f32	9	2	studies	study	NOUN
v979v122f32	9	3	have	have	AUX
v979v122f32	9	4	found	find	VERB
v979v122f32	9	5	that	that	SCONJ
v979v122f32	9	6	treatment	treatment	NOUN
v979v122f32	9	7	of	of	ADP
v979v122f32	9	8	normal	normal	ADJ
v979v122f32	9	9	mammary	mammary	ADJ
v979v122f32	9	10	epithelial	epithelial	ADJ
v979v122f32	9	11	cells	cell	NOUN
v979v122f32	9	12	with	with	ADP
v979v122f32	9	13	conditioned	condition	VERB
v979v122f32	9	14	media	medium	NOUN
v979v122f32	9	15	from	from	ADP
v979v122f32	9	16	senescent	senescent	NOUN
v979v122f32	9	17	fibroblasts	fibroblast	NOUN
v979v122f32	9	18	(	(	PUNCT
v979v122f32	9	19	sasp	sasp	PROPN
v979v122f32	9	20	cm	cm	PROPN
v979v122f32	9	21	)	)	PUNCT
v979v122f32	9	22	results	result	NOUN
v979v122f32	9	23	in	in	ADP
v979v122f32	9	24	a	a	DET
v979v122f32	9	25	robust	robust	ADJ
v979v122f32	9	26	caspase	caspase	NOUN
v979v122f32	9	27	1	1	NUM
v979v122f32	9	28	dependent	dependent	ADJ
v979v122f32	9	29	,	,	PUNCT
v979v122f32	9	30	pyroptotic	pyroptotic	ADJ
v979v122f32	9	31	cell	cell	NOUN
v979v122f32	9	32	death	death	NOUN
v979v122f32	9	33	in	in	ADP
v979v122f32	9	34	three	three	NUM
v979v122f32	9	35	normal	normal	ADJ
v979v122f32	9	36	mammary	mammary	ADJ
v979v122f32	9	37	epithelial	epithelial	ADJ
v979v122f32	9	38	cell	cell	NOUN
v979v122f32	9	39	lines	line	NOUN
v979v122f32	9	40	.	.	PUNCT
v979v122f32	10	1	the	the	DET
v979v122f32	10	2	capacity	capacity	NOUN
v979v122f32	10	3	of	of	ADP
v979v122f32	10	4	sasp	sasp	NOUN
v979v122f32	10	5	cm	cm	PROPN
v979v122f32	10	6	to	to	PART
v979v122f32	10	7	cause	cause	VERB
v979v122f32	10	8	cell	cell	NOUN
v979v122f32	10	9	death	death	NOUN
v979v122f32	10	10	is	be	AUX
v979v122f32	10	11	maintained	maintain	VERB
v979v122f32	10	12	across	across	ADP
v979v122f32	10	13	multiple	multiple	ADJ
v979v122f32	10	14	senescence	senescence	NOUN
v979v122f32	10	15	-	-	PUNCT
v979v122f32	10	16	inducing	induce	VERB
v979v122f32	10	17	stimuli	stimulus	NOUN
v979v122f32	10	18	,	,	PUNCT
v979v122f32	10	19	including	include	VERB
v979v122f32	10	20	bis	bis	PROPN
v979v122f32	10	21	and	and	CCONJ
v979v122f32	10	22	ois	ois	VERB
v979v122f32	10	23	.	.	PUNCT
v979v122f32	11	1	moreover	moreover	ADV
v979v122f32	11	2	,	,	PUNCT
v979v122f32	11	3	the	the	DET
v979v122f32	11	4	addition	addition	NOUN
v979v122f32	11	5	of	of	ADP
v979v122f32	11	6	hras	hras	X
v979v122f32	11	7	(	(	PUNCT
v979v122f32	11	8	g12v	g12v	PROPN
v979v122f32	11	9	)	)	PUNCT
v979v122f32	11	10	or	or	CCONJ
v979v122f32	11	11	erbb2	erbb2	NOUN
v979v122f32	11	12	into	into	ADP
v979v122f32	11	13	normal	normal	ADJ
v979v122f32	11	14	mammary	mammary	ADJ
v979v122f32	11	15	epithelial	epithelial	ADJ
v979v122f32	11	16	cells	cell	NOUN
v979v122f32	11	17	mitigates	mitigate	VERB
v979v122f32	11	18	the	the	DET
v979v122f32	11	19	ability	ability	NOUN
v979v122f32	11	20	of	of	ADP
v979v122f32	11	21	sasp	sasp	NOUN
v979v122f32	11	22	cm	cm	PROPN
v979v122f32	11	23	to	to	PART
v979v122f32	11	24	induce	induce	VERB
v979v122f32	11	25	cell	cell	NOUN
v979v122f32	11	26	death	death	NOUN
v979v122f32	11	27	.	.	PUNCT
v979v122f32	12	1	furthermore	furthermore	ADV
v979v122f32	12	2	,	,	PUNCT
v979v122f32	12	3	mda	mda	ADJ
v979v122f32	12	4	-	-	PUNCT
v979v122f32	12	5	mb-231	mb-231	ADJ
v979v122f32	12	6	and	and	CCONJ
v979v122f32	12	7	mdamb-436	mdamb-436	ADJ
v979v122f32	12	8	breast	breast	NOUN
v979v122f32	12	9	cancer	cancer	NOUN
v979v122f32	12	10	cells	cell	NOUN
v979v122f32	12	11	also	also	ADV
v979v122f32	12	12	attenuated	attenuate	VERB
v979v122f32	12	13	the	the	DET
v979v122f32	12	14	ability	ability	NOUN
v979v122f32	12	15	of	of	ADP
v979v122f32	12	16	sasp	sasp	NOUN
v979v122f32	12	17	cm	cm	PROPN
v979v122f32	12	18	to	to	PART
v979v122f32	12	19	induce	induce	VERB
v979v122f32	12	20	celldeath	celldeath	NOUN
v979v122f32	12	21	.	.	PUNCT
v979v122f32	13	1	while	while	SCONJ
v979v122f32	13	2	the	the	DET
v979v122f32	13	3	role	role	NOUN
v979v122f32	13	4	of	of	ADP
v979v122f32	13	5	senescent	senescent	NOUN
v979v122f32	13	6	fibroblasts	fibroblast	NOUN
v979v122f32	13	7	in	in	ADP
v979v122f32	13	8	cancer	cancer	NOUN
v979v122f32	13	9	has	have	AUX
v979v122f32	13	10	been	be	AUX
v979v122f32	13	11	well	well	ADV
v979v122f32	13	12	characterized	characterize	VERB
v979v122f32	13	13	,	,	PUNCT
v979v122f32	13	14	further	further	ADJ
v979v122f32	13	15	studies	study	NOUN
v979v122f32	13	16	are	be	AUX
v979v122f32	13	17	needed	need	VERB
v979v122f32	13	18	to	to	PART
v979v122f32	13	19	elucidate	elucidate	VERB
v979v122f32	13	20	the	the	DET
v979v122f32	13	21	impact	impact	NOUN
v979v122f32	13	22	of	of	ADP
v979v122f32	13	23	senescent	senescent	NOUN
v979v122f32	13	24	fibroblasts	fibroblast	NOUN
v979v122f32	13	25	and	and	CCONJ
v979v122f32	13	26	their	their	PRON
v979v122f32	13	27	sasp	sasp	NOUN
v979v122f32	13	28	factors	factor	NOUN
v979v122f32	13	29	on	on	ADP
v979v122f32	13	30	the	the	DET
v979v122f32	13	31	surrounding	surround	VERB
v979v122f32	13	32	cell	cell	NOUN
v979v122f32	13	33	non	non	ADJ
v979v122f32	13	34	-	-	ADJ
v979v122f32	13	35	cancerous	cancerous	ADJ
v979v122f32	13	36	cell	cell	NOUN
v979v122f32	13	37	types	type	NOUN
v979v122f32	13	38	including	include	VERB
v979v122f32	13	39	endothelial	endothelial	ADJ
v979v122f32	13	40	cells	cell	NOUN
v979v122f32	13	41	,	,	PUNCT
v979v122f32	13	42	other	other	ADJ
v979v122f32	13	43	fibroblasts	fibroblast	NOUN
v979v122f32	13	44	,	,	PUNCT
v979v122f32	13	45	or	or	CCONJ
v979v122f32	13	46	immune	immune	ADJ
v979v122f32	13	47	cells	cell	NOUN
v979v122f32	13	48	.	.	PUNCT
v979v122f32	14	1	greater	great	ADJ
v979v122f32	14	2	characterization	characterization	NOUN
v979v122f32	14	3	of	of	ADP
v979v122f32	14	4	the	the	DET
v979v122f32	14	5	context	context	NOUN
v979v122f32	14	6	,	,	PUNCT
v979v122f32	14	7	cell	cell	NOUN
v979v122f32	14	8	type	type	NOUN
v979v122f32	14	9	and	and	CCONJ
v979v122f32	14	10	senescence	senescence	NOUN
v979v122f32	14	11	inducer	inducer	NOUN
v979v122f32	14	12	specific	specific	ADJ
v979v122f32	14	13	effects	effect	NOUN
v979v122f32	14	14	of	of	ADP
v979v122f32	14	15	sasp	sasp	NOUN
v979v122f32	14	16	from	from	ADP
v979v122f32	14	17	senescent	senescent	NOUN
v979v122f32	14	18	cells	cell	NOUN
v979v122f32	14	19	will	will	AUX
v979v122f32	14	20	be	be	AUX
v979v122f32	14	21	important	important	ADJ
v979v122f32	14	22	in	in	ADP
v979v122f32	14	23	informing	inform	VERB
v979v122f32	14	24	the	the	DET
v979v122f32	14	25	use	use	NOUN
v979v122f32	14	26	of	of	ADP
v979v122f32	14	27	therapeutic	therapeutic	ADJ
v979v122f32	14	28	avenues	avenue	NOUN
v979v122f32	14	29	such	such	ADJ
v979v122f32	14	30	as	as	ADP
v979v122f32	14	31	senolytics	senolytic	NOUN
v979v122f32	14	32	,	,	PUNCT
v979v122f32	14	33	which	which	PRON
v979v122f32	14	34	selectively	selectively	ADV
v979v122f32	14	35	eliminate	eliminate	VERB
v979v122f32	14	36	senescent	senescent	NOUN
v979v122f32	14	37	cells	cell	NOUN
v979v122f32	14	38	.	.	PUNCT