id	sid	tid	token	lemma	pos
v405s755w17	1	1	this	this	DET
v405s755w17	1	2	thesis	thesis	NOUN
v405s755w17	1	3	describes	describe	VERB
v405s755w17	1	4	my	my	PRON
v405s755w17	1	5	work	work	NOUN
v405s755w17	1	6	on	on	ADP
v405s755w17	1	7	antibiotics	antibiotic	NOUN
v405s755w17	1	8	against	against	ADP
v405s755w17	1	9	methicillin	methicillin	NOUN
v405s755w17	1	10	-	-	PUNCT
v405s755w17	1	11	resistant	resistant	ADJ
v405s755w17	1	12	staphylococcus	staphylococcus	PROPN
v405s755w17	1	13	aureus	aureus	PROPN
v405s755w17	1	14	(	(	PUNCT
v405s755w17	1	15	mrsa	mrsa	PROPN
v405s755w17	1	16	)	)	PUNCT
v405s755w17	1	17	and	and	CCONJ
v405s755w17	1	18	clostridioides	clostridioide	NOUN
v405s755w17	1	19	difficile	difficile	ADJ
v405s755w17	1	20	(	(	PUNCT
v405s755w17	1	21	c.	c.	PROPN
v405s755w17	1	22	difficile	difficile	PROPN
v405s755w17	1	23	)	)	PUNCT
v405s755w17	1	24	,	,	PUNCT
v405s755w17	1	25	which	which	PRON
v405s755w17	1	26	are	be	AUX
v405s755w17	1	27	the	the	DET
v405s755w17	1	28	leading	lead	VERB
v405s755w17	1	29	causes	cause	NOUN
v405s755w17	1	30	of	of	ADP
v405s755w17	1	31	death	death	NOUN
v405s755w17	1	32	associated	associate	VERB
v405s755w17	1	33	with	with	ADP
v405s755w17	1	34	antimicrobial	antimicrobial	ADJ
v405s755w17	1	35	resistance	resistance	NOUN
v405s755w17	1	36	in	in	ADP
v405s755w17	1	37	the	the	DET
v405s755w17	1	38	united	united	PROPN
v405s755w17	1	39	states	states	PROPN
v405s755w17	1	40	.	.	PUNCT
v405s755w17	2	1	structure	structure	NOUN
v405s755w17	2	2	-	-	PUNCT
v405s755w17	2	3	activity	activity	NOUN
v405s755w17	2	4	relationship	relationship	NOUN
v405s755w17	2	5	(	(	PUNCT
v405s755w17	2	6	sar	sar	PROPN
v405s755w17	2	7	)	)	PUNCT
v405s755w17	2	8	study	study	NOUN
v405s755w17	2	9	of	of	ADP
v405s755w17	2	10	quinazolinones	quinazolinone	NOUN
v405s755w17	2	11	against	against	ADP
v405s755w17	2	12	mrsa	mrsa	PROPN
v405s755w17	2	13	was	be	AUX
v405s755w17	2	14	carried	carry	VERB
v405s755w17	2	15	out	out	ADP
v405s755w17	2	16	.	.	PUNCT
v405s755w17	3	1	one	one	NUM
v405s755w17	3	2	featured	feature	VERB
v405s755w17	3	3	compound	compound	NOUN
v405s755w17	3	4	exhibited	exhibit	VERB
v405s755w17	3	5	antibacterial	antibacterial	ADJ
v405s755w17	3	6	activity	activity	NOUN
v405s755w17	3	7	of	of	ADP
v405s755w17	3	8	its	its	PRON
v405s755w17	3	9	own	own	ADJ
v405s755w17	3	10	and	and	CCONJ
v405s755w17	3	11	synergized	synergize	VERB
v405s755w17	3	12	with	with	ADP
v405s755w17	3	13	the	the	DET
v405s755w17	3	14	piperacillin	piperacillin	NOUN
v405s755w17	3	15	-	-	PUNCT
v405s755w17	3	16	tazobactam	tazobactam	NOUN
v405s755w17	3	17	(	(	PUNCT
v405s755w17	3	18	tzp	tzp	PROPN
v405s755w17	3	19	)	)	PUNCT
v405s755w17	3	20	combination	combination	NOUN
v405s755w17	3	21	both	both	CCONJ
v405s755w17	3	22	in	in	ADP
v405s755w17	3	23	vitro	vitro	X
v405s755w17	3	24	and	and	CCONJ
v405s755w17	3	25	in	in	ADP
v405s755w17	3	26	vivo	vivo	PROPN
v405s755w17	3	27	.	.	PUNCT
v405s755w17	4	1	the	the	DET
v405s755w17	4	2	synergy	synergy	NOUN
v405s755w17	4	3	is	be	AUX
v405s755w17	4	4	documented	document	VERB
v405s755w17	4	5	and	and	CCONJ
v405s755w17	4	6	rationalized	rationalize	VERB
v405s755w17	4	7	by	by	ADP
v405s755w17	4	8	the	the	DET
v405s755w17	4	9	ability	ability	NOUN
v405s755w17	4	10	of	of	ADP
v405s755w17	4	11	the	the	DET
v405s755w17	4	12	quinazolinones	quinazolinone	NOUN
v405s755w17	4	13	to	to	PART
v405s755w17	4	14	bind	bind	VERB
v405s755w17	4	15	to	to	ADP
v405s755w17	4	16	the	the	DET
v405s755w17	4	17	allosteric	allosteric	NOUN
v405s755w17	4	18	site	site	NOUN
v405s755w17	4	19	of	of	ADP
v405s755w17	4	20	pbp2a	pbp2a	PROPN
v405s755w17	4	21	,	,	PUNCT
v405s755w17	4	22	a	a	DET
v405s755w17	4	23	key	key	ADJ
v405s755w17	4	24	penicillin	penicillin	NOUN
v405s755w17	4	25	-	-	PUNCT
v405s755w17	4	26	binding	bind	VERB
v405s755w17	4	27	protein	protein	NOUN
v405s755w17	4	28	that	that	PRON
v405s755w17	4	29	confers	confer	VERB
v405s755w17	4	30	methicillin	methicillin	PROPN
v405s755w17	4	31	resistance.c	resistance.c	PROPN
v405s755w17	4	32	.	.	PUNCT
v405s755w17	5	1	difficile	difficile	ADJ
v405s755w17	5	2	is	be	AUX
v405s755w17	5	3	an	an	DET
v405s755w17	5	4	important	important	ADJ
v405s755w17	5	5	nosocomial	nosocomial	ADJ
v405s755w17	5	6	pathogen	pathogen	NOUN
v405s755w17	5	7	that	that	PRON
v405s755w17	5	8	causes	cause	VERB
v405s755w17	5	9	recurrent	recurrent	ADJ
v405s755w17	5	10	diarrhea	diarrhea	NOUN
v405s755w17	5	11	and	and	CCONJ
v405s755w17	5	12	colitis	colitis	NOUN
v405s755w17	5	13	.	.	PUNCT
v405s755w17	6	1	the	the	DET
v405s755w17	6	2	troublesome	troublesome	ADJ
v405s755w17	6	3	high	high	ADJ
v405s755w17	6	4	recurrence	recurrence	NOUN
v405s755w17	6	5	of	of	ADP
v405s755w17	6	6	cdi	cdi	ADJ
v405s755w17	6	7	results	result	NOUN
v405s755w17	6	8	primarily	primarily	ADV
v405s755w17	6	9	from	from	ADP
v405s755w17	6	10	c.	c.	PROPN
v405s755w17	6	11	difficile	difficile	PROPN
v405s755w17	6	12	's	's	PART
v405s755w17	6	13	ability	ability	NOUN
v405s755w17	6	14	to	to	PART
v405s755w17	6	15	produce	produce	VERB
v405s755w17	6	16	dormant	dormant	ADJ
v405s755w17	6	17	spores	spore	NOUN
v405s755w17	6	18	that	that	PRON
v405s755w17	6	19	survive	survive	VERB
v405s755w17	6	20	antibiotic	antibiotic	ADJ
v405s755w17	6	21	treatment	treatment	NOUN
v405s755w17	6	22	and	and	CCONJ
v405s755w17	6	23	opportunistically	opportunistically	ADV
v405s755w17	6	24	germinate	germinate	VERB
v405s755w17	6	25	in	in	ADP
v405s755w17	6	26	a	a	DET
v405s755w17	6	27	perturbed	perturb	VERB
v405s755w17	6	28	microbiota	microbiota	NOUN
v405s755w17	6	29	to	to	PART
v405s755w17	6	30	initiate	initiate	VERB
v405s755w17	6	31	more	more	ADJ
v405s755w17	6	32	infection	infection	NOUN
v405s755w17	6	33	.	.	PUNCT
v405s755w17	7	1	oxadiazoles	oxadiazole	NOUN
v405s755w17	7	2	discovered	discover	VERB
v405s755w17	7	3	in	in	ADP
v405s755w17	7	4	our	our	PRON
v405s755w17	7	5	lab	lab	NOUN
v405s755w17	7	6	were	be	AUX
v405s755w17	7	7	found	find	VERB
v405s755w17	7	8	to	to	PART
v405s755w17	7	9	kill	kill	VERB
v405s755w17	7	10	the	the	DET
v405s755w17	7	11	bacterial	bacterial	ADJ
v405s755w17	7	12	cell	cell	NOUN
v405s755w17	7	13	and	and	CCONJ
v405s755w17	7	14	interfere	interfere	VERB
v405s755w17	7	15	with	with	ADP
v405s755w17	7	16	spore	spore	ADJ
v405s755w17	7	17	germination	germination	NOUN
v405s755w17	7	18	,	,	PUNCT
v405s755w17	7	19	which	which	PRON
v405s755w17	7	20	enable	enable	VERB
v405s755w17	7	21	oxadiazoles	oxadiazole	NOUN
v405s755w17	7	22	to	to	PART
v405s755w17	7	23	halt	halt	VERB
v405s755w17	7	24	colonization	colonization	NOUN
v405s755w17	7	25	by	by	ADP
v405s755w17	7	26	vegetative	vegetative	ADJ
v405s755w17	7	27	bacteria	bacteria	NOUN
v405s755w17	7	28	and	and	CCONJ
v405s755w17	7	29	spores.an	spores.an	NUM
v405s755w17	7	30	sar	sar	PROPN
v405s755w17	7	31	study	study	NOUN
v405s755w17	7	32	of	of	ADP
v405s755w17	7	33	the	the	DET
v405s755w17	7	34	oxadiazole	oxadiazole	PROPN
v405s755w17	7	35	antibacterial	antibacterial	NOUN
v405s755w17	7	36	was	be	AUX
v405s755w17	7	37	conducted	conduct	VERB
v405s755w17	7	38	to	to	PART
v405s755w17	7	39	assess	assess	VERB
v405s755w17	7	40	their	their	PRON
v405s755w17	7	41	bactericidal	bactericidal	ADJ
v405s755w17	7	42	activity	activity	NOUN
v405s755w17	7	43	against	against	ADP
v405s755w17	7	44	c.	c.	PROPN
v405s755w17	7	45	difficile	difficile	PROPN
v405s755w17	7	46	vegetative	vegetative	ADJ
v405s755w17	7	47	cells	cell	NOUN
v405s755w17	7	48	.	.	PUNCT
v405s755w17	8	1	an	an	DET
v405s755w17	8	2	oxadiazole	oxadiazole	NOUN
v405s755w17	8	3	-	-	PUNCT
v405s755w17	8	4	nitroimidazole	nitroimidazole	PROPN
v405s755w17	8	5	hybrid	hybrid	NOUN
v405s755w17	8	6	was	be	AUX
v405s755w17	8	7	found	find	VERB
v405s755w17	8	8	to	to	PART
v405s755w17	8	9	show	show	VERB
v405s755w17	8	10	high	high	ADJ
v405s755w17	8	11	selectivity	selectivity	NOUN
v405s755w17	8	12	against	against	ADP
v405s755w17	8	13	c.	c.	PROPN
v405s755w17	8	14	difficile	difficile	NOUN
v405s755w17	8	15	over	over	ADP
v405s755w17	8	16	the	the	DET
v405s755w17	8	17	common	common	ADJ
v405s755w17	8	18	gut	gut	NOUN
v405s755w17	8	19	bacteria	bacteria	NOUN
v405s755w17	8	20	and	and	CCONJ
v405s755w17	8	21	eukaryotic	eukaryotic	ADJ
v405s755w17	8	22	cells	cell	NOUN
v405s755w17	8	23	.	.	PUNCT
v405s755w17	9	1	the	the	DET
v405s755w17	9	2	high	high	ADJ
v405s755w17	9	3	selectivity	selectivity	NOUN
v405s755w17	9	4	of	of	ADP
v405s755w17	9	5	the	the	DET
v405s755w17	9	6	antimicrobial	antimicrobial	ADJ
v405s755w17	9	7	spares	spare	VERB
v405s755w17	9	8	the	the	DET
v405s755w17	9	9	gut	gut	NOUN
v405s755w17	9	10	microbiota	microbiota	NOUN
v405s755w17	9	11	avoiding	avoid	VERB
v405s755w17	9	12	further	further	ADJ
v405s755w17	9	13	spore	spore	ADJ
v405s755w17	9	14	germination	germination	NOUN
v405s755w17	9	15	after	after	ADP
v405s755w17	9	16	the	the	DET
v405s755w17	9	17	treatment	treatment	NOUN
v405s755w17	9	18	.	.	PUNCT
v405s755w17	10	1	this	this	DET
v405s755w17	10	2	new	new	ADJ
v405s755w17	10	3	series	series	NOUN
v405s755w17	10	4	of	of	ADP
v405s755w17	10	5	nontoxic	nontoxic	ADJ
v405s755w17	10	6	,	,	PUNCT
v405s755w17	10	7	narrow	narrow	ADJ
v405s755w17	10	8	-	-	PUNCT
v405s755w17	10	9	spectrum	spectrum	NOUN
v405s755w17	10	10	antibiotic	antibiotic	ADJ
v405s755w17	10	11	holds	hold	VERB
v405s755w17	10	12	promise	promise	NOUN
v405s755w17	10	13	for	for	ADP
v405s755w17	10	14	being	be	AUX
v405s755w17	10	15	a	a	DET
v405s755w17	10	16	better	well	ADJ
v405s755w17	10	17	&	&	CCONJ
v405s755w17	10	18	amp	amp	PROPN
v405s755w17	10	19	;	;	PUNCT
v405s755w17	10	20	cheaper	cheap	ADJ
v405s755w17	10	21	alternative	alternative	NOUN
v405s755w17	10	22	for	for	ADP
v405s755w17	10	23	treating	treat	VERB
v405s755w17	10	24	rcdi	rcdi	ADJ
v405s755w17	10	25	.	.	PUNCT
v405s755w17	11	1	an	an	DET
v405s755w17	11	2	additional	additional	ADJ
v405s755w17	11	3	sar	sar	PROPN
v405s755w17	11	4	study	study	NOUN
v405s755w17	11	5	of	of	ADP
v405s755w17	11	6	the	the	DET
v405s755w17	11	7	oxadiazoles	oxadiazole	NOUN
v405s755w17	11	8	that	that	PRON
v405s755w17	11	9	weighed	weigh	VERB
v405s755w17	11	10	on	on	ADP
v405s755w17	11	11	spore	spore	ADJ
v405s755w17	11	12	germination	germination	NOUN
v405s755w17	11	13	inhibition	inhibition	NOUN
v405s755w17	11	14	were	be	AUX
v405s755w17	11	15	also	also	ADV
v405s755w17	11	16	explored	explore	VERB
v405s755w17	11	17	.	.	PUNCT
v405s755w17	12	1	dual	dual	ADJ
v405s755w17	12	2	-	-	PUNCT
v405s755w17	12	3	acting	act	VERB
v405s755w17	12	4	analogs	analog	NOUN
v405s755w17	12	5	or	or	CCONJ
v405s755w17	12	6	exclusively	exclusively	ADV
v405s755w17	12	7	spore	spore	ADJ
v405s755w17	12	8	germination	germination	NOUN
v405s755w17	12	9	inhibitors	inhibitor	NOUN
v405s755w17	12	10	were	be	AUX
v405s755w17	12	11	discovered.based	discovered.base	VERB
v405s755w17	12	12	on	on	ADP
v405s755w17	12	13	the	the	DET
v405s755w17	12	14	previous	previous	ADJ
v405s755w17	12	15	sar	sar	PROPN
v405s755w17	12	16	discovery	discovery	PROPN
v405s755w17	12	17	,	,	PUNCT
v405s755w17	12	18	oxadiazole	oxadiazole	NOUN
v405s755w17	12	19	probes	probe	NOUN
v405s755w17	12	20	were	be	AUX
v405s755w17	12	21	designed	design	VERB
v405s755w17	12	22	and	and	CCONJ
v405s755w17	12	23	synthesized	synthesize	VERB
v405s755w17	12	24	for	for	ADP
v405s755w17	12	25	target	target	NOUN
v405s755w17	12	26	identification	identification	NOUN
v405s755w17	12	27	.	.	PUNCT
v405s755w17	13	1	proteomics	proteomic	NOUN
v405s755w17	13	2	studies	study	NOUN
v405s755w17	13	3	with	with	ADP
v405s755w17	13	4	oxadiazole	oxadiazole	NOUN
v405s755w17	13	5	analogs	analogs	PROPN
v405s755w17	13	6	/	/	SYM
v405s755w17	13	7	probes	probe	NOUN
v405s755w17	13	8	were	be	AUX
v405s755w17	13	9	carried	carry	VERB
v405s755w17	13	10	out	out	ADP
v405s755w17	13	11	.	.	PUNCT
v405s755w17	14	1	the	the	DET
v405s755w17	14	2	application	application	NOUN
v405s755w17	14	3	of	of	ADP
v405s755w17	14	4	proteomics	proteomic	NOUN
v405s755w17	14	5	study	study	NOUN
v405s755w17	14	6	leads	lead	VERB
v405s755w17	14	7	us	we	PRON
v405s755w17	14	8	to	to	ADP
v405s755w17	14	9	two	two	NUM
v405s755w17	14	10	key	key	ADJ
v405s755w17	14	11	proteins	protein	NOUN
v405s755w17	14	12	involved	involve	VERB
v405s755w17	14	13	with	with	ADP
v405s755w17	14	14	c.	c.	PROPN
v405s755w17	14	15	difficile	difficile	PROPN
v405s755w17	14	16	germination	germination	NOUN
v405s755w17	14	17	,	,	PUNCT
v405s755w17	14	18	which	which	PRON
v405s755w17	14	19	showed	show	VERB
v405s755w17	14	20	strong	strong	ADJ
v405s755w17	14	21	binding	binding	NOUN
v405s755w17	14	22	with	with	ADP
v405s755w17	14	23	oxadiazole	oxadiazole	NOUN
v405s755w17	14	24	antibacterial	antibacterial	ADJ
v405s755w17	14	25	by	by	ADP
v405s755w17	14	26	microscale	microscale	ADJ
v405s755w17	14	27	thermophoresis	thermophoresis	NOUN
v405s755w17	14	28	(	(	PUNCT
v405s755w17	14	29	mst	mst	NOUN
v405s755w17	14	30	)	)	PUNCT
v405s755w17	14	31	binding	bind	VERB
v405s755w17	14	32	assay	assay	NOUN
v405s755w17	14	33	.	.	PUNCT