id sid tid token lemma pos tm70ms3884f 1 1 the the DET tm70ms3884f 1 2 mosquito mosquito PROPN tm70ms3884f 1 3 , , PUNCT tm70ms3884f 1 4 aedes aedes PROPN tm70ms3884f 1 5 aegypti aegypti PROPN tm70ms3884f 1 6 , , PUNCT tm70ms3884f 1 7 is be AUX tm70ms3884f 1 8 responsible responsible ADJ tm70ms3884f 1 9 for for ADP tm70ms3884f 1 10 transmission transmission NOUN tm70ms3884f 1 11 of of ADP tm70ms3884f 1 12 dengue dengue NOUN tm70ms3884f 1 13 and and CCONJ tm70ms3884f 1 14 yellow yellow ADJ tm70ms3884f 1 15 fever fever NOUN tm70ms3884f 1 16 and and CCONJ tm70ms3884f 1 17 serves serve VERB tm70ms3884f 1 18 as as ADP tm70ms3884f 1 19 an an DET tm70ms3884f 1 20 excellent excellent ADJ tm70ms3884f 1 21 model model NOUN tm70ms3884f 1 22 vector vector NOUN tm70ms3884f 1 23 for for ADP tm70ms3884f 1 24 transmission transmission NOUN tm70ms3884f 1 25 of of ADP tm70ms3884f 1 26 malaria malaria NOUN tm70ms3884f 1 27 and and CCONJ tm70ms3884f 1 28 lymphatic lymphatic ADJ tm70ms3884f 1 29 filariasis filariasis NOUN tm70ms3884f 1 30 . . PUNCT tm70ms3884f 2 1 understanding understand VERB tm70ms3884f 2 2 the the DET tm70ms3884f 2 3 genetics genetic NOUN tm70ms3884f 2 4 of of ADP tm70ms3884f 2 5 vector vector NOUN tm70ms3884f 2 6 competence competence NOUN tm70ms3884f 2 7 could could AUX tm70ms3884f 2 8 allow allow VERB tm70ms3884f 2 9 for for ADP tm70ms3884f 2 10 the the DET tm70ms3884f 2 11 development development NOUN tm70ms3884f 2 12 of of ADP tm70ms3884f 2 13 vector vector NOUN tm70ms3884f 2 14 - - PUNCT tm70ms3884f 2 15 based base VERB tm70ms3884f 2 16 control control NOUN tm70ms3884f 2 17 strategies strategy NOUN tm70ms3884f 2 18 that that PRON tm70ms3884f 2 19 would would AUX tm70ms3884f 2 20 alleviate alleviate VERB tm70ms3884f 2 21 mortality mortality NOUN tm70ms3884f 2 22 and and CCONJ tm70ms3884f 2 23 morbidity morbidity NOUN tm70ms3884f 2 24 worldwide worldwide ADV tm70ms3884f 2 25 . . PUNCT tm70ms3884f 3 1 in in ADP tm70ms3884f 3 2 the the DET tm70ms3884f 3 3 first first ADJ tm70ms3884f 3 4 study study NOUN tm70ms3884f 3 5 we we PRON tm70ms3884f 3 6 developed develop VERB tm70ms3884f 3 7 genetic genetic ADJ tm70ms3884f 3 8 markers marker NOUN tm70ms3884f 3 9 based base VERB tm70ms3884f 3 10 upon upon SCONJ tm70ms3884f 3 11 chromosomal chromosomal ADJ tm70ms3884f 3 12 regions region NOUN tm70ms3884f 3 13 conserved conserve VERB tm70ms3884f 3 14 throughout throughout ADP tm70ms3884f 3 15 the the DET tm70ms3884f 3 16 culicidae culicidae PROPN tm70ms3884f 3 17 . . PUNCT tm70ms3884f 4 1 we we PRON tm70ms3884f 4 2 designed design VERB tm70ms3884f 4 3 35 35 NUM tm70ms3884f 4 4 pcr pcr NOUN tm70ms3884f 4 5 primer primer NOUN tm70ms3884f 4 6 pairs pair NOUN tm70ms3884f 4 7 based base VERB tm70ms3884f 4 8 upon upon SCONJ tm70ms3884f 4 9 orthologous orthologous ADJ tm70ms3884f 4 10 exons exon NOUN tm70ms3884f 4 11 in in ADP tm70ms3884f 4 12 aedes aedes PROPN tm70ms3884f 4 13 aegypti aegypti PROPN tm70ms3884f 4 14 and and CCONJ tm70ms3884f 4 15 drosophila drosophila NOUN tm70ms3884f 4 16 melanogaster melanogaster NOUN tm70ms3884f 4 17 or or CCONJ tm70ms3884f 4 18 anopheles anophele NOUN tm70ms3884f 4 19 gambiae gambiae NOUN tm70ms3884f 4 20 . . PUNCT tm70ms3884f 5 1 twenty twenty NUM tm70ms3884f 5 2 - - PUNCT tm70ms3884f 5 3 three three NUM tm70ms3884f 5 4 of of ADP tm70ms3884f 5 5 the the DET tm70ms3884f 5 6 primers primer NOUN tm70ms3884f 5 7 yielded yield VERB tm70ms3884f 5 8 a a DET tm70ms3884f 5 9 single single ADJ tm70ms3884f 5 10 pcr pcr NOUN tm70ms3884f 5 11 product product NOUN tm70ms3884f 5 12 in in ADP tm70ms3884f 5 13 at at ADV tm70ms3884f 5 14 least least ADV tm70ms3884f 5 15 one one NUM tm70ms3884f 5 16 dipteran dipteran NOUN tm70ms3884f 5 17 in in ADP tm70ms3884f 5 18 addition addition NOUN tm70ms3884f 5 19 to to ADP tm70ms3884f 5 20 a. a. PROPN tm70ms3884f 5 21 aegypti aegypti PROPN tm70ms3884f 5 22 when when SCONJ tm70ms3884f 5 23 screened screen VERB tm70ms3884f 5 24 with with ADP tm70ms3884f 5 25 genomic genomic ADJ tm70ms3884f 5 26 dna dna PROPN tm70ms3884f 5 27 from from ADP tm70ms3884f 5 28 seven seven NUM tm70ms3884f 5 29 dipterans dipteran NOUN tm70ms3884f 5 30 including include VERB tm70ms3884f 5 31 five five NUM tm70ms3884f 5 32 mosquito mosquito PROPN tm70ms3884f 5 33 species specie NOUN tm70ms3884f 5 34 . . PUNCT tm70ms3884f 6 1 eight eight NUM tm70ms3884f 6 2 of of ADP tm70ms3884f 6 3 the the DET tm70ms3884f 6 4 primers primer NOUN tm70ms3884f 6 5 amplified amplify VERB tm70ms3884f 6 6 a a DET tm70ms3884f 6 7 single single ADJ tm70ms3884f 6 8 pcr pcr NOUN tm70ms3884f 6 9 product product NOUN tm70ms3884f 6 10 in in ADP tm70ms3884f 6 11 only only ADV tm70ms3884f 6 12 a. a. NOUN tm70ms3884f 6 13 aegypti aegypti PROPN tm70ms3884f 6 14 while while SCONJ tm70ms3884f 6 15 four four NUM tm70ms3884f 6 16 primer primer NOUN tm70ms3884f 6 17 pairs pair NOUN tm70ms3884f 6 18 gave give VERB tm70ms3884f 6 19 no no DET tm70ms3884f 6 20 pcr pcr NOUN tm70ms3884f 6 21 product product NOUN tm70ms3884f 6 22 in in ADP tm70ms3884f 6 23 any any DET tm70ms3884f 6 24 species specie NOUN tm70ms3884f 6 25 . . PUNCT tm70ms3884f 7 1 the the DET tm70ms3884f 7 2 23 23 NUM tm70ms3884f 7 3 successful successful ADJ tm70ms3884f 7 4 cats cat NOUN tm70ms3884f 7 5 primer primer NOUN tm70ms3884f 7 6 pairs pair NOUN tm70ms3884f 7 7 gave give VERB tm70ms3884f 7 8 broad broad ADJ tm70ms3884f 7 9 genome genome NOUN tm70ms3884f 7 10 coverage coverage NOUN tm70ms3884f 7 11 in in ADP tm70ms3884f 7 12 a. a. PROPN tm70ms3884f 7 13 aegypti aegypti PROPN tm70ms3884f 7 14 and and CCONJ tm70ms3884f 7 15 demonstrate demonstrate VERB tm70ms3884f 7 16 an an DET tm70ms3884f 7 17 efficient efficient ADJ tm70ms3884f 7 18 strategy strategy NOUN tm70ms3884f 7 19 for for ADP tm70ms3884f 7 20 developing develop VERB tm70ms3884f 7 21 comparative comparative ADJ tm70ms3884f 7 22 anchor anchor NOUN tm70ms3884f 7 23 marker marker NOUN tm70ms3884f 7 24 loci locus NOUN tm70ms3884f 7 25 for for ADP tm70ms3884f 7 26 any any DET tm70ms3884f 7 27 species specie NOUN tm70ms3884f 7 28 of of ADP tm70ms3884f 7 29 culicidae culicidae PROPN tm70ms3884f 7 30 . . PUNCT tm70ms3884f 8 1 in in ADP tm70ms3884f 8 2 the the DET tm70ms3884f 8 3 second second ADJ tm70ms3884f 8 4 study study NOUN tm70ms3884f 8 5 we we PRON tm70ms3884f 8 6 isolated isolate VERB tm70ms3884f 8 7 and and CCONJ tm70ms3884f 8 8 identified identify VERB tm70ms3884f 8 9 microsatellite microsatellite NOUN tm70ms3884f 8 10 sequences sequence NOUN tm70ms3884f 8 11 from from ADP tm70ms3884f 8 12 multiple multiple ADJ tm70ms3884f 8 13 genomic genomic NOUN tm70ms3884f 8 14 libraries library NOUN tm70ms3884f 8 15 for for ADP tm70ms3884f 8 16 a. a. PROPN tm70ms3884f 8 17 aegypti aegypti PROPN tm70ms3884f 8 18 . . PUNCT tm70ms3884f 9 1 we we PRON tm70ms3884f 9 2 identified identify VERB tm70ms3884f 9 3 seven seven NUM tm70ms3884f 9 4 single single ADJ tm70ms3884f 9 5 - - PUNCT tm70ms3884f 9 6 copy copy NOUN tm70ms3884f 9 7 simple simple ADJ tm70ms3884f 9 8 microsatellites microsatellite NOUN tm70ms3884f 9 9 from from ADP tm70ms3884f 9 10 three three NUM tm70ms3884f 9 11 plasmid plasmid ADJ tm70ms3884f 9 12 libraries library NOUN tm70ms3884f 9 13 enriched enrich VERB tm70ms3884f 9 14 for for ADP tm70ms3884f 9 15 ( ( PUNCT tm70ms3884f 9 16 ga)n ga)n PROPN tm70ms3884f 9 17 , , PUNCT tm70ms3884f 9 18 ( ( PUNCT tm70ms3884f 9 19 aat)n aat)n PROPN tm70ms3884f 9 20 and and CCONJ tm70ms3884f 9 21 ( ( PUNCT tm70ms3884f 9 22 taga)n taga)n NOUN tm70ms3884f 9 23 motifs motif NOUN tm70ms3884f 9 24 from from ADP tm70ms3884f 9 25 a. a. PROPN tm70ms3884f 9 26 aegypti aegypti PROPN tm70ms3884f 9 27 . . PUNCT tm70ms3884f 10 1 in in ADP tm70ms3884f 10 2 addition addition NOUN tm70ms3884f 10 3 , , PUNCT tm70ms3884f 10 4 we we PRON tm70ms3884f 10 5 identified identify VERB tm70ms3884f 10 6 5 5 NUM tm70ms3884f 10 7 single single ADJ tm70ms3884f 10 8 - - PUNCT tm70ms3884f 10 9 copy copy NOUN tm70ms3884f 10 10 microsatellites microsatellite NOUN tm70ms3884f 10 11 from from ADP tm70ms3884f 10 12 an an DET tm70ms3884f 10 13 a. a. NOUN tm70ms3884f 10 14 aegypti aegypti PROPN tm70ms3884f 10 15 cosmid cosmid PROPN tm70ms3884f 10 16 library library NOUN tm70ms3884f 10 17 . . PUNCT tm70ms3884f 11 1 seven seven NUM tm70ms3884f 11 2 of of ADP tm70ms3884f 11 3 these these DET tm70ms3884f 11 4 microsatellite microsatellite NOUN tm70ms3884f 11 5 markers marker NOUN tm70ms3884f 11 6 were be AUX tm70ms3884f 11 7 polymorphic polymorphic ADJ tm70ms3884f 11 8 and and CCONJ tm70ms3884f 11 9 were be AUX tm70ms3884f 11 10 genetically genetically ADV tm70ms3884f 11 11 mapped map VERB tm70ms3884f 11 12 in in ADP tm70ms3884f 11 13 a a DET tm70ms3884f 11 14 segregating segregating ADJ tm70ms3884f 11 15 f1 f1 PROPN tm70ms3884f 11 16 intercross intercross ADJ tm70ms3884f 11 17 population population NOUN tm70ms3884f 11 18 . . PUNCT tm70ms3884f 12 1 these these DET tm70ms3884f 12 2 markers marker NOUN tm70ms3884f 12 3 greatly greatly ADV tm70ms3884f 12 4 increase increase VERB tm70ms3884f 12 5 the the DET tm70ms3884f 12 6 number number NOUN tm70ms3884f 12 7 of of ADP tm70ms3884f 12 8 microsatellite microsatellite NOUN tm70ms3884f 12 9 markers marker NOUN tm70ms3884f 12 10 available available ADJ tm70ms3884f 12 11 for for ADP tm70ms3884f 12 12 a. a. NOUN tm70ms3884f 12 13 aegypti aegypti PROPN tm70ms3884f 12 14 and and CCONJ tm70ms3884f 12 15 provide provide VERB tm70ms3884f 12 16 additional additional ADJ tm70ms3884f 12 17 tools tool NOUN tm70ms3884f 12 18 for for ADP tm70ms3884f 12 19 studying study VERB tm70ms3884f 12 20 genetic genetic ADJ tm70ms3884f 12 21 variability variability NOUN tm70ms3884f 12 22 of of ADP tm70ms3884f 12 23 mosquito mosquito NOUN tm70ms3884f 12 24 populations population NOUN tm70ms3884f 12 25 . . PUNCT tm70ms3884f 13 1 additionally additionally ADV tm70ms3884f 13 2 , , PUNCT tm70ms3884f 13 3 most most ADJ tm70ms3884f 13 4 a. a. NOUN tm70ms3884f 13 5 aegypti aegypti PROPN tm70ms3884f 13 6 microsatellites microsatellite NOUN tm70ms3884f 13 7 are be AUX tm70ms3884f 13 8 closely closely ADV tm70ms3884f 13 9 associated associate VERB tm70ms3884f 13 10 with with ADP tm70ms3884f 13 11 repetitive repetitive ADJ tm70ms3884f 13 12 elements element NOUN tm70ms3884f 13 13 , , PUNCT tm70ms3884f 13 14 accounting account VERB tm70ms3884f 13 15 for for ADP tm70ms3884f 13 16 our our PRON tm70ms3884f 13 17 and and CCONJ tm70ms3884f 13 18 other other ADJ tm70ms3884f 13 19 researchers researcher NOUN tm70ms3884f 13 20 limited limit VERB tm70ms3884f 13 21 success success NOUN tm70ms3884f 13 22 in in ADP tm70ms3884f 13 23 developing develop VERB tm70ms3884f 13 24 an an DET tm70ms3884f 13 25 extensive extensive ADJ tm70ms3884f 13 26 panel panel NOUN tm70ms3884f 13 27 of of ADP tm70ms3884f 13 28 microsatellite microsatellite PROPN tm70ms3884f 13 29 marker marker NOUN tm70ms3884f 13 30 loci locus NOUN tm70ms3884f 13 31 . . PUNCT tm70ms3884f 14 1 in in ADP tm70ms3884f 14 2 the the DET tm70ms3884f 14 3 third third ADJ tm70ms3884f 14 4 aim aim NOUN tm70ms3884f 14 5 of of ADP tm70ms3884f 14 6 this this DET tm70ms3884f 14 7 study study NOUN tm70ms3884f 14 8 we we PRON tm70ms3884f 14 9 employed employ VERB tm70ms3884f 14 10 single single ADJ tm70ms3884f 14 11 nucleotide nucleotide NOUN tm70ms3884f 14 12 polymorphism polymorphism NOUN tm70ms3884f 14 13 ( ( PUNCT tm70ms3884f 14 14 snp snp PROPN tm70ms3884f 14 15 ) ) PUNCT tm70ms3884f 14 16 markers marker NOUN tm70ms3884f 14 17 to to PART tm70ms3884f 14 18 analyze analyze VERB tm70ms3884f 14 19 an an DET tm70ms3884f 14 20 advanced advanced ADJ tm70ms3884f 14 21 intercross intercross ADJ tm70ms3884f 14 22 line line NOUN tm70ms3884f 14 23 for for ADP tm70ms3884f 14 24 quantitative quantitative ADJ tm70ms3884f 14 25 trait trait NOUN tm70ms3884f 14 26 loci locus NOUN tm70ms3884f 14 27 associated associate VERB tm70ms3884f 14 28 with with ADP tm70ms3884f 14 29 brugia brugia PROPN tm70ms3884f 14 30 malayi malayi PROPN tm70ms3884f 14 31 susceptibility susceptibility NOUN tm70ms3884f 14 32 . . PUNCT tm70ms3884f 15 1 using use VERB tm70ms3884f 15 2 single single ADJ tm70ms3884f 15 3 marker marker NOUN tm70ms3884f 15 4 analysis analysis NOUN tm70ms3884f 15 5 of of ADP tm70ms3884f 15 6 variance variance NOUN tm70ms3884f 15 7 and and CCONJ tm70ms3884f 15 8 linear linear ADJ tm70ms3884f 15 9 regression regression NOUN tm70ms3884f 15 10 we we PRON tm70ms3884f 15 11 identified identify VERB tm70ms3884f 15 12 a a DET tm70ms3884f 15 13 single single ADJ tm70ms3884f 15 14 qtl qtl NOUN tm70ms3884f 15 15 at at ADP tm70ms3884f 15 16 lf178 lf178 PROPN tm70ms3884f 15 17 associated associate VERB tm70ms3884f 15 18 with with ADP tm70ms3884f 15 19 susceptibility susceptibility NOUN tm70ms3884f 15 20 when when SCONJ tm70ms3884f 15 21 evaluated evaluate VERB tm70ms3884f 15 22 as as ADP tm70ms3884f 15 23 a a DET tm70ms3884f 15 24 quantitative quantitative ADJ tm70ms3884f 15 25 phenotype phenotype NOUN tm70ms3884f 15 26 and and CCONJ tm70ms3884f 15 27 we we PRON tm70ms3884f 15 28 identified identify VERB tm70ms3884f 15 29 one one NUM tm70ms3884f 15 30 qtl qtl NOUN tm70ms3884f 15 31 for for ADP tm70ms3884f 15 32 susceptibility susceptibility NOUN tm70ms3884f 15 33 when when SCONJ tm70ms3884f 15 34 the the DET tm70ms3884f 15 35 phenotype phenotype NOUN tm70ms3884f 15 36 was be AUX tm70ms3884f 15 37 treated treat VERB tm70ms3884f 15 38 as as ADP tm70ms3884f 15 39 binary binary ADJ tm70ms3884f 15 40 trait trait NOUN tm70ms3884f 15 41 . . PUNCT