id	sid	tid	token	lemma	pos
td96k072t2q	1	1	artemisinin	artemisinin	ADJ
td96k072t2q	1	2	combination	combination	NOUN
td96k072t2q	1	3	therapies	therapy	NOUN
td96k072t2q	1	4	(	(	PUNCT
td96k072t2q	1	5	acts	act	NOUN
td96k072t2q	1	6	)	)	PUNCT
td96k072t2q	1	7	are	be	AUX
td96k072t2q	1	8	frontline	frontline	NOUN
td96k072t2q	1	9	,	,	PUNCT
td96k072t2q	1	10	fast	fast	ADV
td96k072t2q	1	11	-	-	PUNCT
td96k072t2q	1	12	acting	act	VERB
td96k072t2q	1	13	drugs	drug	NOUN
td96k072t2q	1	14	that	that	PRON
td96k072t2q	1	15	have	have	AUX
td96k072t2q	1	16	been	be	AUX
td96k072t2q	1	17	key	key	ADJ
td96k072t2q	1	18	in	in	ADP
td96k072t2q	1	19	helping	help	VERB
td96k072t2q	1	20	reduce	reduce	VERB
td96k072t2q	1	21	the	the	DET
td96k072t2q	1	22	burden	burden	NOUN
td96k072t2q	1	23	of	of	ADP
td96k072t2q	1	24	malaria	malaria	NOUN
td96k072t2q	1	25	cases	case	NOUN
td96k072t2q	1	26	and	and	CCONJ
td96k072t2q	1	27	deaths	death	NOUN
td96k072t2q	1	28	.	.	PUNCT
td96k072t2q	2	1	however	however	ADV
td96k072t2q	2	2	,	,	PUNCT
td96k072t2q	2	3	malaria	malaria	NOUN
td96k072t2q	2	4	parasites	parasite	NOUN
td96k072t2q	2	5	are	be	AUX
td96k072t2q	2	6	developing	develop	VERB
td96k072t2q	2	7	resistance	resistance	NOUN
td96k072t2q	2	8	to	to	ADP
td96k072t2q	2	9	artemisinins	artemisinin	NOUN
td96k072t2q	2	10	,	,	PUNCT
td96k072t2q	2	11	threatening	threaten	VERB
td96k072t2q	2	12	global	global	ADJ
td96k072t2q	2	13	malaria	malaria	NOUN
td96k072t2q	2	14	control	control	NOUN
td96k072t2q	2	15	and	and	CCONJ
td96k072t2q	2	16	elimination	elimination	NOUN
td96k072t2q	2	17	.	.	PUNCT
td96k072t2q	3	1	through	through	ADP
td96k072t2q	3	2	the	the	DET
td96k072t2q	3	3	use	use	NOUN
td96k072t2q	3	4	of	of	ADP
td96k072t2q	3	5	whole	whole	ADJ
td96k072t2q	3	6	-	-	PUNCT
td96k072t2q	3	7	genome	genome	NOUN
td96k072t2q	3	8	sequencing	sequencing	NOUN
td96k072t2q	3	9	(	(	PUNCT
td96k072t2q	3	10	wgs	wgs	NOUN
td96k072t2q	3	11	)	)	PUNCT
td96k072t2q	3	12	of	of	ADP
td96k072t2q	3	13	artemisinin	artemisinin	PROPN
td96k072t2q	3	14	resistant	resistant	ADJ
td96k072t2q	3	15	parasites	parasite	NOUN
td96k072t2q	3	16	,	,	PUNCT
td96k072t2q	3	17	mutations	mutation	NOUN
td96k072t2q	3	18	in	in	ADP
td96k072t2q	3	19	pfkelch13	pfkelch13	ADJ
td96k072t2q	3	20	(	(	PUNCT
td96k072t2q	3	21	k13	k13	PROPN
td96k072t2q	3	22	)	)	PUNCT
td96k072t2q	3	23	were	be	AUX
td96k072t2q	3	24	shown	show	VERB
td96k072t2q	3	25	to	to	PART
td96k072t2q	3	26	be	be	AUX
td96k072t2q	3	27	associated	associate	VERB
td96k072t2q	3	28	with	with	ADP
td96k072t2q	3	29	resistance	resistance	NOUN
td96k072t2q	3	30	both	both	CCONJ
td96k072t2q	3	31	in	in	ADP
td96k072t2q	3	32	vitro	vitro	X
td96k072t2q	3	33	and	and	CCONJ
td96k072t2q	3	34	in	in	ADP
td96k072t2q	3	35	vivo	vivo	PROPN
td96k072t2q	3	36	.	.	PROPN
td96k072t2q	4	1	from	from	ADP
td96k072t2q	4	2	its	its	PRON
td96k072t2q	4	3	sequence	sequence	NOUN
td96k072t2q	4	4	and	and	CCONJ
td96k072t2q	4	5	predicted	predict	VERB
td96k072t2q	4	6	molecular	molecular	ADJ
td96k072t2q	4	7	structure	structure	NOUN
td96k072t2q	4	8	,	,	PUNCT
td96k072t2q	4	9	k13	k13	PROPN
td96k072t2q	4	10	was	be	AUX
td96k072t2q	4	11	predicted	predict	VERB
td96k072t2q	4	12	to	to	PART
td96k072t2q	4	13	be	be	AUX
td96k072t2q	4	14	a	a	DET
td96k072t2q	4	15	substrate	substrate	NOUN
td96k072t2q	4	16	adapter	adapter	NOUN
td96k072t2q	4	17	involved	involve	VERB
td96k072t2q	4	18	in	in	ADP
td96k072t2q	4	19	target	target	NOUN
td96k072t2q	4	20	identification	identification	NOUN
td96k072t2q	4	21	,	,	PUNCT
td96k072t2q	4	22	binding	binding	NOUN
td96k072t2q	4	23	,	,	PUNCT
td96k072t2q	4	24	ubiquitination	ubiquitination	NOUN
td96k072t2q	4	25	and	and	CCONJ
td96k072t2q	4	26	subsequent	subsequent	ADJ
td96k072t2q	4	27	degradation	degradation	NOUN
td96k072t2q	4	28	of	of	ADP
td96k072t2q	4	29	select	select	ADJ
td96k072t2q	4	30	substrates	substrate	NOUN
td96k072t2q	4	31	,	,	PUNCT
td96k072t2q	4	32	keeping	keep	VERB
td96k072t2q	4	33	their	their	PRON
td96k072t2q	4	34	levels	level	NOUN
td96k072t2q	4	35	low	low	ADJ
td96k072t2q	4	36	to	to	PART
td96k072t2q	4	37	maintain	maintain	VERB
td96k072t2q	4	38	proper	proper	ADJ
td96k072t2q	4	39	cellular	cellular	ADJ
td96k072t2q	4	40	homeostasis	homeostasis	NOUN
td96k072t2q	4	41	.	.	PUNCT
td96k072t2q	5	1	identification	identification	NOUN
td96k072t2q	5	2	of	of	ADP
td96k072t2q	5	3	a	a	DET
td96k072t2q	5	4	molecular	molecular	ADJ
td96k072t2q	5	5	marker	marker	NOUN
td96k072t2q	5	6	of	of	ADP
td96k072t2q	5	7	resistance	resistance	NOUN
td96k072t2q	5	8	led	lead	VERB
td96k072t2q	5	9	to	to	ADP
td96k072t2q	5	10	the	the	DET
td96k072t2q	5	11	identification	identification	NOUN
td96k072t2q	5	12	of	of	ADP
td96k072t2q	5	13	underlying	underlie	VERB
td96k072t2q	5	14	mechanisms	mechanism	NOUN
td96k072t2q	5	15	.	.	PUNCT
td96k072t2q	6	1	two	two	NUM
td96k072t2q	6	2	major	major	ADJ
td96k072t2q	6	3	k13	k13	NOUN
td96k072t2q	6	4	effector	effector	NOUN
td96k072t2q	6	5	mechanisms	mechanism	NOUN
td96k072t2q	6	6	have	have	AUX
td96k072t2q	6	7	been	be	AUX
td96k072t2q	6	8	proposed	propose	VERB
td96k072t2q	6	9	to	to	PART
td96k072t2q	6	10	overcome	overcome	VERB
td96k072t2q	6	11	artemisinin	artemisinin	ADV
td96k072t2q	6	12	-	-	PUNCT
td96k072t2q	6	13	induced	induce	VERB
td96k072t2q	6	14	proteopathy	proteopathy	ADJ
td96k072t2q	6	15	and	and	CCONJ
td96k072t2q	6	16	death	death	NOUN
td96k072t2q	6	17	.	.	PUNCT
td96k072t2q	7	1	they	they	PRON
td96k072t2q	7	2	are	be	AUX
td96k072t2q	7	3	,	,	PUNCT
td96k072t2q	7	4	firstly	firstly	ADV
td96k072t2q	7	5	,	,	PUNCT
td96k072t2q	7	6	proteostatic	proteostatic	ADJ
td96k072t2q	7	7	dysregulation	dysregulation	NOUN
td96k072t2q	7	8	of	of	ADP
td96k072t2q	7	9	parasite	parasite	NOUN
td96k072t2q	7	10	phosphatidylinositol-3	phosphatidylinositol-3	NOUN
td96k072t2q	7	11	-	-	PROPN
td96k072t2q	7	12	kinase	kinase	ADJ
td96k072t2q	7	13	(	(	PUNCT
td96k072t2q	7	14	pi3k	pi3k	X
td96k072t2q	7	15	)	)	PUNCT
td96k072t2q	7	16	resulting	result	VERB
td96k072t2q	7	17	in	in	ADP
td96k072t2q	7	18	elevation	elevation	NOUN
td96k072t2q	7	19	of	of	ADP
td96k072t2q	7	20	parasite	parasite	NOUN
td96k072t2q	7	21	pi3p	pi3p	PROPN
td96k072t2q	7	22	and	and	CCONJ
td96k072t2q	7	23	second	second	ADJ
td96k072t2q	7	24	,	,	PUNCT
td96k072t2q	7	25	the	the	DET
td96k072t2q	7	26	upregulation	upregulation	NOUN
td96k072t2q	7	27	of	of	ADP
td96k072t2q	7	28	parasite	parasite	NOUN
td96k072t2q	7	29	oxidative	oxidative	ADJ
td96k072t2q	7	30	stress	stress	NOUN
td96k072t2q	7	31	and	and	CCONJ
td96k072t2q	7	32	protein	protein	NOUN
td96k072t2q	7	33	damage	damage	NOUN
td96k072t2q	7	34	pathways	pathway	NOUN
td96k072t2q	7	35	via	via	ADP
td96k072t2q	7	36	the	the	DET
td96k072t2q	7	37	unfolded	unfolded	ADJ
td96k072t2q	7	38	protein	protein	NOUN
td96k072t2q	7	39	response	response	NOUN
td96k072t2q	7	40	(	(	PUNCT
td96k072t2q	7	41	upr	upr	PROPN
td96k072t2q	7	42	)	)	PUNCT
td96k072t2q	7	43	.	.	PUNCT
td96k072t2q	8	1	however	however	ADV
td96k072t2q	8	2	,	,	PUNCT
td96k072t2q	8	3	how	how	SCONJ
td96k072t2q	8	4	these	these	DET
td96k072t2q	8	5	two	two	NUM
td96k072t2q	8	6	mechanisms	mechanism	NOUN
td96k072t2q	8	7	were	be	AUX
td96k072t2q	8	8	related	relate	VERB
td96k072t2q	8	9	(	(	PUNCT
td96k072t2q	8	10	if	if	SCONJ
td96k072t2q	8	11	they	they	PRON
td96k072t2q	8	12	were	be	AUX
td96k072t2q	8	13	at	at	ADV
td96k072t2q	8	14	all	all	ADV
td96k072t2q	8	15	)	)	PUNCT
td96k072t2q	8	16	and	and	CCONJ
td96k072t2q	8	17	the	the	DET
td96k072t2q	8	18	dynamics	dynamic	NOUN
td96k072t2q	8	19	of	of	ADP
td96k072t2q	8	20	pi3p	pi3p	PROPN
td96k072t2q	8	21	,	,	PUNCT
td96k072t2q	8	22	k13	k13	NOUN
td96k072t2q	8	23	and	and	CCONJ
td96k072t2q	8	24	proteostasis	proteostasis	NOUN
td96k072t2q	8	25	systems	system	NOUN
td96k072t2q	8	26	that	that	PRON
td96k072t2q	8	27	included	include	VERB
td96k072t2q	8	28	the	the	DET
td96k072t2q	8	29	upr	upr	NOUN
td96k072t2q	8	30	had	have	AUX
td96k072t2q	8	31	not	not	PART
td96k072t2q	8	32	yet	yet	ADV
td96k072t2q	8	33	been	be	AUX
td96k072t2q	8	34	delineated	delineate	VERB
td96k072t2q	8	35	.	.	PUNCT
td96k072t2q	9	1	our	our	PRON
td96k072t2q	9	2	work	work	NOUN
td96k072t2q	9	3	used	use	VERB
td96k072t2q	9	4	bioinformatic	bioinformatic	ADJ
td96k072t2q	9	5	and	and	CCONJ
td96k072t2q	9	6	computational	computational	ADJ
td96k072t2q	9	7	methods	method	NOUN
td96k072t2q	9	8	along	along	ADP
td96k072t2q	9	9	with	with	ADP
td96k072t2q	9	10	cryoimmunoelectron	cryoimmunoelectron	NOUN
td96k072t2q	9	11	microscopy	microscopy	NOUN
td96k072t2q	9	12	to	to	PART
td96k072t2q	9	13	show	show	VERB
td96k072t2q	9	14	that	that	SCONJ
td96k072t2q	9	15	k13	k13	NOUN
td96k072t2q	9	16	concentrates	concentrate	VERB
td96k072t2q	9	17	at	at	ADP
td96k072t2q	9	18	pi3p	pi3p	ADJ
td96k072t2q	9	19	vesicles	vesicle	NOUN
td96k072t2q	9	20	/	/	SYM
td96k072t2q	9	21	tubules	tubule	NOUN
td96k072t2q	9	22	in	in	ADP
td96k072t2q	9	23	the	the	DET
td96k072t2q	9	24	parasite	parasite	NOUN
td96k072t2q	9	25	endoplasmic	endoplasmic	NOUN
td96k072t2q	9	26	reticulum	reticulum	NOUN
td96k072t2q	9	27	(	(	PUNCT
td96k072t2q	9	28	er	er	INTJ
td96k072t2q	9	29	)	)	PUNCT
td96k072t2q	9	30	in	in	ADP
td96k072t2q	9	31	p.	p.	PROPN
td96k072t2q	9	32	falciparum	falciparum	NOUN
td96k072t2q	9	33	infected	infect	VERB
td96k072t2q	9	34	erythrocytes	erythrocyte	NOUN
td96k072t2q	9	35	.	.	PUNCT
td96k072t2q	10	1	we	we	PRON
td96k072t2q	10	2	also	also	ADV
td96k072t2q	10	3	showed	show	VERB
td96k072t2q	10	4	that	that	SCONJ
td96k072t2q	10	5	k13	k13	NOUN
td96k072t2q	10	6	copurified	copurifie	VERB
td96k072t2q	10	7	with	with	ADP
td96k072t2q	10	8	the	the	DET
td96k072t2q	10	9	parasite	parasite	NOUN
td96k072t2q	10	10	virulence	virulence	NOUN
td96k072t2q	10	11	adhesin	adhesin	PROPN
td96k072t2q	10	12	pfemp1	pfemp1	PROPN
td96k072t2q	10	13	.	.	PUNCT
td96k072t2q	10	14	isolation	isolation	NOUN
td96k072t2q	10	15	and	and	CCONJ
td96k072t2q	10	16	subsequent	subsequent	ADJ
td96k072t2q	10	17	analysis	analysis	NOUN
td96k072t2q	10	18	of	of	ADP
td96k072t2q	10	19	the	the	DET
td96k072t2q	10	20	pfemp1	pfemp1	PROPN
td96k072t2q	10	21	-	-	PUNCT
td96k072t2q	10	22	k13	k13	PROPN
td96k072t2q	10	23	immunoproteome	immunoproteome	PROPN
td96k072t2q	10	24	showed	show	VERB
td96k072t2q	10	25	that	that	SCONJ
td96k072t2q	10	26	this	this	DET
td96k072t2q	10	27	proteome	proteome	NOUN
td96k072t2q	10	28	is	be	AUX
td96k072t2q	10	29	comprehensively	comprehensively	ADV
td96k072t2q	10	30	enriched	enrich	VERB
td96k072t2q	10	31	in	in	ADP
td96k072t2q	10	32	multiple	multiple	ADJ
td96k072t2q	10	33	systems	system	NOUN
td96k072t2q	10	34	of	of	ADP
td96k072t2q	10	35	proteostasis	proteostasis	NOUN
td96k072t2q	10	36	including	include	VERB
td96k072t2q	10	37	protein	protein	NOUN
td96k072t2q	10	38	export	export	NOUN
td96k072t2q	10	39	,	,	PUNCT
td96k072t2q	10	40	quality	quality	NOUN
td96k072t2q	10	41	control	control	NOUN
td96k072t2q	10	42	,	,	PUNCT
td96k072t2q	10	43	protein	protein	NOUN
td96k072t2q	10	44	folding	fold	VERB
td96k072t2q	10	45	in	in	ADP
td96k072t2q	10	46	the	the	DET
td96k072t2q	10	47	er	er	INTJ
td96k072t2q	10	48	and	and	CCONJ
td96k072t2q	10	49	cytoplasm	cytoplasm	NOUN
td96k072t2q	10	50	and	and	CCONJ
td96k072t2q	10	51	the	the	DET
td96k072t2q	10	52	upr	upr	NOUN
td96k072t2q	10	53	.	.	PUNCT
td96k072t2q	11	1	these	these	DET
td96k072t2q	11	2	findings	finding	NOUN
td96k072t2q	11	3	were	be	AUX
td96k072t2q	11	4	validated	validate	VERB
td96k072t2q	11	5	by	by	ADP
td96k072t2q	11	6	showing	show	VERB
td96k072t2q	11	7	that	that	SCONJ
td96k072t2q	11	8	the	the	DET
td96k072t2q	11	9	major	major	ADJ
td96k072t2q	11	10	resistance	resistance	NOUN
td96k072t2q	11	11	marker	marker	NOUN
td96k072t2q	11	12	k13c580y	k13c580y	PUNCT
td96k072t2q	11	13	quantitatively	quantitatively	ADV
td96k072t2q	11	14	increased	increase	VERB
td96k072t2q	11	15	pi3p	pi3p	ADJ
td96k072t2q	11	16	tubules	tubule	NOUN
td96k072t2q	11	17	and	and	CCONJ
td96k072t2q	11	18	vesicles	vesicle	NOUN
td96k072t2q	11	19	,	,	PUNCT
td96k072t2q	11	20	exporting	export	VERB
td96k072t2q	11	21	them	they	PRON
td96k072t2q	11	22	throughout	throughout	ADP
td96k072t2q	11	23	the	the	DET
td96k072t2q	11	24	parasite	parasite	NOUN
td96k072t2q	11	25	and	and	CCONJ
td96k072t2q	11	26	the	the	DET
td96k072t2q	11	27	host	host	NOUN
td96k072t2q	11	28	red	red	ADJ
td96k072t2q	11	29	cell	cell	NOUN
td96k072t2q	11	30	.	.	PUNCT
td96k072t2q	12	1	the	the	DET
td96k072t2q	12	2	amplification	amplification	NOUN
td96k072t2q	12	3	of	of	ADP
td96k072t2q	12	4	these	these	DET
td96k072t2q	12	5	vesicles	vesicle	NOUN
td96k072t2q	12	6	containing	contain	VERB
td96k072t2q	12	7	signatures	signature	NOUN
td96k072t2q	12	8	of	of	ADP
td96k072t2q	12	9	proteostatic	proteostatic	ADJ
td96k072t2q	12	10	control	control	NOUN
td96k072t2q	12	11	that	that	PRON
td96k072t2q	12	12	disseminate	disseminate	VERB
td96k072t2q	12	13	throughout	throughout	ADP
td96k072t2q	12	14	the	the	DET
td96k072t2q	12	15	parasite	parasite	NOUN
td96k072t2q	12	16	might	might	AUX
td96k072t2q	12	17	be	be	AUX
td96k072t2q	12	18	involved	involve	VERB
td96k072t2q	12	19	in	in	ADP
td96k072t2q	12	20	neutralizing	neutralize	VERB
td96k072t2q	12	21	the	the	DET
td96k072t2q	12	22	toxic	toxic	ADJ
td96k072t2q	12	23	proteopathy	proteopathy	ADJ
td96k072t2q	12	24	artemisinins	artemisinin	NOUN
td96k072t2q	12	25	cause	cause	VERB
td96k072t2q	12	26	in	in	ADP
td96k072t2q	12	27	the	the	DET
td96k072t2q	12	28	parasite	parasite	NOUN
td96k072t2q	12	29	.	.	PUNCT
td96k072t2q	13	1	while	while	SCONJ
td96k072t2q	13	2	these	these	DET
td96k072t2q	13	3	findings	finding	NOUN
td96k072t2q	13	4	were	be	AUX
td96k072t2q	13	5	focused	focus	VERB
td96k072t2q	13	6	on	on	ADP
td96k072t2q	13	7	the	the	DET
td96k072t2q	13	8	major	major	ADJ
td96k072t2q	13	9	resistance	resistance	NOUN
td96k072t2q	13	10	mutation	mutation	NOUN
td96k072t2q	13	11	in	in	ADP
td96k072t2q	13	12	south	south	PROPN
td96k072t2q	13	13	east	east	PROPN
td96k072t2q	13	14	asia	asia	PROPN
td96k072t2q	13	15	(	(	PUNCT
td96k072t2q	13	16	sea	sea	PROPN
td96k072t2q	13	17	)	)	PUNCT
td96k072t2q	13	18	,	,	PUNCT
td96k072t2q	13	19	k13c580y	k13c580y	SPACE
td96k072t2q	13	20	,	,	PUNCT
td96k072t2q	13	21	we	we	PRON
td96k072t2q	13	22	expanded	expand	VERB
td96k072t2q	13	23	our	our	PRON
td96k072t2q	13	24	studies	study	NOUN
td96k072t2q	13	25	to	to	PART
td96k072t2q	13	26	encompass	encompass	VERB
td96k072t2q	13	27	all	all	PRON
td96k072t2q	13	28	known	know	VERB
td96k072t2q	13	29	k13	k13	NOUN
td96k072t2q	13	30	polymorphisms	polymorphism	NOUN
td96k072t2q	13	31	identified	identify	VERB
td96k072t2q	13	32	in	in	ADP
td96k072t2q	13	33	asia	asia	PROPN
td96k072t2q	13	34	and	and	CCONJ
td96k072t2q	13	35	africa	africa	PROPN
td96k072t2q	13	36	(	(	PUNCT
td96k072t2q	13	37	over	over	ADP
td96k072t2q	13	38	200	200	NUM
td96k072t2q	13	39	polymorphisms	polymorphism	NOUN
td96k072t2q	13	40	)	)	PUNCT
td96k072t2q	13	41	.	.	PUNCT
td96k072t2q	14	1	since	since	SCONJ
td96k072t2q	14	2	different	different	ADJ
td96k072t2q	14	3	polymorphisms	polymorphism	NOUN
td96k072t2q	14	4	lead	lead	VERB
td96k072t2q	14	5	to	to	ADP
td96k072t2q	14	6	different	different	ADJ
td96k072t2q	14	7	levels	level	NOUN
td96k072t2q	14	8	of	of	ADP
td96k072t2q	14	9	resistant	resistant	ADJ
td96k072t2q	14	10	(	(	PUNCT
td96k072t2q	14	11	if	if	SCONJ
td96k072t2q	14	12	at	at	ADV
td96k072t2q	14	13	all	all	ADV
td96k072t2q	14	14	)	)	PUNCT
td96k072t2q	14	15	,	,	PUNCT
td96k072t2q	14	16	we	we	PRON
td96k072t2q	14	17	developed	develop	VERB
td96k072t2q	14	18	an	an	DET
td96k072t2q	14	19	in	in	ADP
td96k072t2q	14	20	silico	silico	NOUN
td96k072t2q	14	21	tool	tool	NOUN
td96k072t2q	14	22	to	to	PART
td96k072t2q	14	23	separate	separate	VERB
td96k072t2q	14	24	resistance	resistance	NOUN
td96k072t2q	14	25	causing	cause	VERB
td96k072t2q	14	26	mutations	mutation	NOUN
td96k072t2q	14	27	from	from	ADP
td96k072t2q	14	28	sensitive	sensitive	ADJ
td96k072t2q	14	29	ones	one	NOUN
td96k072t2q	14	30	.	.	PUNCT
td96k072t2q	15	1	we	we	PRON
td96k072t2q	15	2	can	can	AUX
td96k072t2q	15	3	use	use	VERB
td96k072t2q	15	4	this	this	DET
td96k072t2q	15	5	tool	tool	NOUN
td96k072t2q	15	6	to	to	PART
td96k072t2q	15	7	distinguish	distinguish	VERB
td96k072t2q	15	8	between	between	ADP
td96k072t2q	15	9	sensitive	sensitive	ADJ
td96k072t2q	15	10	polymorphisms	polymorphism	NOUN
td96k072t2q	15	11	and	and	CCONJ
td96k072t2q	15	12	resistance	resistance	NOUN
td96k072t2q	15	13	mutations	mutation	NOUN
td96k072t2q	15	14	in	in	ADP
td96k072t2q	15	15	malaria	malaria	NOUN
td96k072t2q	15	16	endemic	endemic	ADJ
td96k072t2q	15	17	regions	region	NOUN
td96k072t2q	15	18	.	.	PUNCT
td96k072t2q	16	1	overall	overall	ADV
td96k072t2q	16	2	,	,	PUNCT
td96k072t2q	16	3	through	through	ADP
td96k072t2q	16	4	our	our	PRON
td96k072t2q	16	5	computational	computational	ADJ
td96k072t2q	16	6	analyses	analysis	NOUN
td96k072t2q	16	7	presented	present	VERB
td96k072t2q	16	8	here	here	ADV
td96k072t2q	16	9	,	,	PUNCT
td96k072t2q	16	10	we	we	PRON
td96k072t2q	16	11	provide	provide	VERB
td96k072t2q	16	12	several	several	ADJ
td96k072t2q	16	13	insights	insight	NOUN
td96k072t2q	16	14	into	into	ADP
td96k072t2q	16	15	the	the	DET
td96k072t2q	16	16	role	role	NOUN
td96k072t2q	16	17	and	and	CCONJ
td96k072t2q	16	18	function	function	NOUN
td96k072t2q	16	19	of	of	ADP
td96k072t2q	16	20	the	the	DET
td96k072t2q	16	21	artemisinin	artemisinin	PROPN
td96k072t2q	16	22	resistance	resistance	PROPN
td96k072t2q	16	23	marker	marker	NOUN
td96k072t2q	16	24	pfk13	pfk13	NOUN
td96k072t2q	16	25	.	.	PUNCT
td96k072t2q	17	1	we	we	PRON
td96k072t2q	17	2	show	show	VERB
td96k072t2q	17	3	that	that	SCONJ
td96k072t2q	17	4	k13	k13	NOUN
td96k072t2q	17	5	is	be	AUX
td96k072t2q	17	6	a	a	DET
td96k072t2q	17	7	marker	marker	NOUN
td96k072t2q	17	8	for	for	ADP
td96k072t2q	17	9	parasite	parasite	NOUN
td96k072t2q	17	10	pi3p	pi3p	ADJ
td96k072t2q	17	11	,	,	PUNCT
td96k072t2q	17	12	concentrating	concentrate	VERB
td96k072t2q	17	13	in	in	ADP
td96k072t2q	17	14	vesicles	vesicle	NOUN
td96k072t2q	17	15	in	in	ADP
td96k072t2q	17	16	the	the	DET
td96k072t2q	17	17	er	er	INTJ
td96k072t2q	17	18	.	.	PUNCT
td96k072t2q	17	19	expansion	expansion	NOUN
td96k072t2q	17	20	of	of	ADP
td96k072t2q	17	21	these	these	DET
td96k072t2q	17	22	vesicles	vesicle	NOUN
td96k072t2q	17	23	(	(	PUNCT
td96k072t2q	17	24	containing	contain	VERB
td96k072t2q	17	25	pathways	pathway	NOUN
td96k072t2q	17	26	of	of	ADP
td96k072t2q	17	27	protein	protein	NOUN
td96k072t2q	17	28	proteostasis	proteostasis	NOUN
td96k072t2q	17	29	and	and	CCONJ
td96k072t2q	17	30	the	the	DET
td96k072t2q	17	31	upr	upr	NOUN
td96k072t2q	17	32	)	)	PUNCT
td96k072t2q	17	33	might	might	AUX
td96k072t2q	17	34	confer	confer	VERB
td96k072t2q	17	35	resistance	resistance	NOUN
td96k072t2q	17	36	by	by	ADP
td96k072t2q	17	37	disseminating	disseminate	VERB
td96k072t2q	17	38	resistance	resistance	NOUN
td96k072t2q	17	39	intermediates	intermediate	NOUN
td96k072t2q	17	40	to	to	PART
td96k072t2q	17	41	mitigate	mitigate	VERB
td96k072t2q	17	42	the	the	DET
td96k072t2q	17	43	promiscuous	promiscuous	ADJ
td96k072t2q	17	44	artemisinin	artemisinin	ADV
td96k072t2q	17	45	-	-	PUNCT
td96k072t2q	17	46	induced	induce	VERB
td96k072t2q	17	47	proteopathy	proteopathy	ADJ
td96k072t2q	17	48	throughout	throughout	ADP
td96k072t2q	17	49	the	the	DET
td96k072t2q	17	50	infected	infected	ADJ
td96k072t2q	17	51	erythrocyte	erythrocyte	NOUN
td96k072t2q	17	52	.	.	PUNCT
td96k072t2q	18	1	we	we	PRON
td96k072t2q	18	2	also	also	ADV
td96k072t2q	18	3	develop	develop	VERB
td96k072t2q	18	4	an	an	DET
td96k072t2q	18	5	in	in	ADP
td96k072t2q	18	6	silico	silico	NOUN
td96k072t2q	18	7	tool	tool	NOUN
td96k072t2q	18	8	to	to	PART
td96k072t2q	18	9	show	show	VERB
td96k072t2q	18	10	how	how	SCONJ
td96k072t2q	18	11	different	different	ADJ
td96k072t2q	18	12	polymorphisms	polymorphism	NOUN
td96k072t2q	18	13	along	along	ADP
td96k072t2q	18	14	k13	k13	NOUN
td96k072t2q	18	15	might	might	AUX
td96k072t2q	18	16	be	be	AUX
td96k072t2q	18	17	involved	involve	VERB
td96k072t2q	18	18	in	in	ADP
td96k072t2q	18	19	this	this	DET
td96k072t2q	18	20	mechanism	mechanism	NOUN
td96k072t2q	18	21	of	of	ADP
td96k072t2q	18	22	resistance	resistance	NOUN
td96k072t2q	18	23	.	.	PUNCT