id	sid	tid	token	lemma	pos
td96k072f40	1	1	mycobacterium	mycobacterium	NOUN
td96k072f40	1	2	tuberculosis	tuberculosis	NOUN
td96k072f40	1	3	(	(	PUNCT
td96k072f40	1	4	m.tb	m.tb	PROPN
td96k072f40	1	5	)	)	PUNCT
td96k072f40	1	6	,	,	PUNCT
td96k072f40	1	7	the	the	DET
td96k072f40	1	8	causative	causative	ADJ
td96k072f40	1	9	agent	agent	NOUN
td96k072f40	1	10	of	of	ADP
td96k072f40	1	11	tb	tb	PROPN
td96k072f40	1	12	,	,	PUNCT
td96k072f40	1	13	is	be	AUX
td96k072f40	1	14	the	the	DET
td96k072f40	1	15	leading	lead	VERB
td96k072f40	1	16	cause	cause	NOUN
td96k072f40	1	17	of	of	ADP
td96k072f40	1	18	death	death	NOUN
td96k072f40	1	19	due	due	ADP
td96k072f40	1	20	to	to	ADP
td96k072f40	1	21	an	an	DET
td96k072f40	1	22	infection	infection	NOUN
td96k072f40	1	23	recently	recently	ADV
td96k072f40	1	24	overtaking	overtake	VERB
td96k072f40	1	25	hiv	hiv	PROPN
td96k072f40	1	26	in	in	ADP
td96k072f40	1	27	this	this	DET
td96k072f40	1	28	dubious	dubious	ADJ
td96k072f40	1	29	category	category	NOUN
td96k072f40	1	30	.	.	PUNCT
td96k072f40	2	1	m.tb	m.tb	PRON
td96k072f40	2	2	is	be	AUX
td96k072f40	2	3	an	an	DET
td96k072f40	2	4	intracellular	intracellular	ADJ
td96k072f40	2	5	pathogen	pathogen	NOUN
td96k072f40	2	6	that	that	PRON
td96k072f40	2	7	primarily	primarily	ADV
td96k072f40	2	8	infects	infect	VERB
td96k072f40	2	9	macrophages	macrophage	NOUN
td96k072f40	2	10	.	.	PUNCT
td96k072f40	3	1	the	the	DET
td96k072f40	3	2	major	major	ADJ
td96k072f40	3	3	focus	focus	NOUN
td96k072f40	3	4	of	of	ADP
td96k072f40	3	5	our	our	PRON
td96k072f40	3	6	laboratory	laboratory	NOUN
td96k072f40	3	7	is	be	AUX
td96k072f40	3	8	to	to	PART
td96k072f40	3	9	understand	understand	VERB
td96k072f40	3	10	how	how	SCONJ
td96k072f40	3	11	this	this	DET
td96k072f40	3	12	intracellular	intracellular	ADJ
td96k072f40	3	13	pathogen	pathogen	NOUN
td96k072f40	3	14	interacts	interact	VERB
td96k072f40	3	15	with	with	ADP
td96k072f40	3	16	the	the	DET
td96k072f40	3	17	host	host	NOUN
td96k072f40	3	18	immune	immune	ADJ
td96k072f40	3	19	system	system	NOUN
td96k072f40	3	20	focusing	focus	VERB
td96k072f40	3	21	primarily	primarily	ADV
td96k072f40	3	22	on	on	ADP
td96k072f40	3	23	exosomes	exosome	NOUN
td96k072f40	3	24	,	,	PUNCT
td96k072f40	3	25	which	which	PRON
td96k072f40	3	26	are	be	AUX
td96k072f40	3	27	bioactive	bioactive	ADJ
td96k072f40	3	28	vesicles	vesicle	NOUN
td96k072f40	3	29	of	of	ADP
td96k072f40	3	30	30	30	NUM
td96k072f40	3	31	-	-	SYM
td96k072f40	3	32	150	150	NUM
td96k072f40	3	33	nm	nm	NOUN
td96k072f40	3	34	in	in	ADP
td96k072f40	3	35	size	size	NOUN
td96k072f40	3	36	that	that	PRON
td96k072f40	3	37	facilitate	facilitate	VERB
td96k072f40	3	38	intercellular	intercellular	ADJ
td96k072f40	3	39	communication	communication	NOUN
td96k072f40	3	40	,	,	PUNCT
td96k072f40	3	41	and	and	CCONJ
td96k072f40	3	42	how	how	SCONJ
td96k072f40	3	43	they	they	PRON
td96k072f40	3	44	may	may	AUX
td96k072f40	3	45	be	be	AUX
td96k072f40	3	46	involved	involve	VERB
td96k072f40	3	47	in	in	ADP
td96k072f40	3	48	modulating	modulate	VERB
td96k072f40	3	49	the	the	DET
td96k072f40	3	50	host	host	NOUN
td96k072f40	3	51	immune	immune	ADJ
td96k072f40	3	52	response	response	NOUN
td96k072f40	3	53	.	.	PUNCT
td96k072f40	4	1	although	although	SCONJ
td96k072f40	4	2	a	a	DET
td96k072f40	4	3	significant	significant	ADJ
td96k072f40	4	4	effort	effort	NOUN
td96k072f40	4	5	has	have	AUX
td96k072f40	4	6	focused	focus	VERB
td96k072f40	4	7	on	on	ADP
td96k072f40	4	8	characterizing	characterize	VERB
td96k072f40	4	9	host	host	NOUN
td96k072f40	4	10	cell	cell	NOUN
td96k072f40	4	11	responses	response	NOUN
td96k072f40	4	12	to	to	ADP
td96k072f40	4	13	antigen	antigen	ADV
td96k072f40	4	14	-	-	PUNCT
td96k072f40	4	15	loaded	load	VERB
td96k072f40	4	16	exosomes	exosome	NOUN
td96k072f40	4	17	,	,	PUNCT
td96k072f40	4	18	we	we	PRON
td96k072f40	4	19	know	know	VERB
td96k072f40	4	20	little	little	ADJ
td96k072f40	4	21	about	about	ADP
td96k072f40	4	22	how	how	SCONJ
td96k072f40	4	23	exosomes	exosome	NOUN
td96k072f40	4	24	affect	affect	VERB
td96k072f40	4	25	cellular	cellular	ADJ
td96k072f40	4	26	function	function	NOUN
td96k072f40	4	27	of	of	ADP
td96k072f40	4	28	the	the	DET
td96k072f40	4	29	endothelium	endothelium	NOUN
td96k072f40	4	30	,	,	PUNCT
td96k072f40	4	31	which	which	PRON
td96k072f40	4	32	is	be	AUX
td96k072f40	4	33	an	an	DET
td96k072f40	4	34	important	important	ADJ
td96k072f40	4	35	regulator	regulator	NOUN
td96k072f40	4	36	of	of	ADP
td96k072f40	4	37	host	host	NOUN
td96k072f40	4	38	immune	immune	ADJ
td96k072f40	4	39	response	response	NOUN
td96k072f40	4	40	during	during	ADP
td96k072f40	4	41	an	an	DET
td96k072f40	4	42	m.tb	m.tb	PROPN
td96k072f40	4	43	infection	infection	NOUN
td96k072f40	4	44	.	.	PUNCT
td96k072f40	5	1	this	this	DET
td96k072f40	5	2	dissertation	dissertation	NOUN
td96k072f40	5	3	aims	aim	VERB
td96k072f40	5	4	to	to	PART
td96k072f40	5	5	characterize	characterize	VERB
td96k072f40	5	6	the	the	DET
td96k072f40	5	7	interaction	interaction	NOUN
td96k072f40	5	8	between	between	ADP
td96k072f40	5	9	endothelial	endothelial	ADJ
td96k072f40	5	10	cells	cell	NOUN
td96k072f40	5	11	and	and	CCONJ
td96k072f40	5	12	exosomes	exosome	NOUN
td96k072f40	5	13	derived	derive	VERB
td96k072f40	5	14	from	from	ADP
td96k072f40	5	15	m.tb	m.tb	PROPN
td96k072f40	5	16	-	-	PUNCT
td96k072f40	5	17	infected	infect	VERB
td96k072f40	5	18	macrophages	macrophage	NOUN
td96k072f40	5	19	.	.	PUNCT
td96k072f40	6	1	we	we	PRON
td96k072f40	6	2	also	also	ADV
td96k072f40	6	3	studied	study	VERB
td96k072f40	6	4	how	how	SCONJ
td96k072f40	6	5	exosomes	exosome	NOUN
td96k072f40	6	6	isolated	isolate	VERB
td96k072f40	6	7	from	from	ADP
td96k072f40	6	8	the	the	DET
td96k072f40	6	9	serum	serum	NOUN
td96k072f40	6	10	of	of	ADP
td96k072f40	6	11	m.tb	m.tb	PROPN
td96k072f40	6	12	-	-	PUNCT
td96k072f40	6	13	infected	infect	VERB
td96k072f40	6	14	mice	mouse	NOUN
td96k072f40	6	15	modulated	modulate	VERB
td96k072f40	6	16	endothelial	endothelial	ADJ
td96k072f40	6	17	cellular	cellular	ADJ
td96k072f40	6	18	function	function	NOUN
td96k072f40	6	19	ex-vivo.our	ex-vivo.our	PRON
td96k072f40	6	20	previous	previous	ADJ
td96k072f40	6	21	studies	study	NOUN
td96k072f40	6	22	indicate	indicate	VERB
td96k072f40	6	23	that	that	SCONJ
td96k072f40	6	24	exosomes	exosome	NOUN
td96k072f40	6	25	released	release	VERB
td96k072f40	6	26	from	from	ADP
td96k072f40	6	27	m.tb	m.tb	PROPN
td96k072f40	6	28	-	-	PUNCT
td96k072f40	6	29	infected	infect	VERB
td96k072f40	6	30	macrophages	macrophage	NOUN
td96k072f40	6	31	contain	contain	VERB
td96k072f40	6	32	soluble	soluble	ADJ
td96k072f40	6	33	mycobacterial	mycobacterial	ADJ
td96k072f40	6	34	proteins	protein	NOUN
td96k072f40	6	35	that	that	PRON
td96k072f40	6	36	can	can	AUX
td96k072f40	6	37	function	function	VERB
td96k072f40	6	38	in	in	ADP
td96k072f40	6	39	modulating	modulate	VERB
td96k072f40	6	40	the	the	DET
td96k072f40	6	41	innate	innate	ADJ
td96k072f40	6	42	and	and	CCONJ
td96k072f40	6	43	acquired	acquire	VERB
td96k072f40	6	44	immune	immune	ADJ
td96k072f40	6	45	response	response	NOUN
td96k072f40	6	46	.	.	PUNCT
td96k072f40	7	1	interestingly	interestingly	ADV
td96k072f40	7	2	,	,	PUNCT
td96k072f40	7	3	during	during	ADP
td96k072f40	7	4	a	a	DET
td96k072f40	7	5	mouse	mouse	NOUN
td96k072f40	7	6	m.tb	m.tb	NOUN
td96k072f40	7	7	or	or	CCONJ
td96k072f40	7	8	m.bovis	m.bovis	PROPN
td96k072f40	7	9	bcg	bcg	PROPN
td96k072f40	7	10	infection	infection	NOUN
td96k072f40	7	11	exosome	exosome	NOUN
td96k072f40	7	12	concentration	concentration	NOUN
td96k072f40	7	13	in	in	ADP
td96k072f40	7	14	serum	serum	NOUN
td96k072f40	7	15	correlated	correlate	VERB
td96k072f40	7	16	with	with	ADP
td96k072f40	7	17	bacterial	bacterial	ADJ
td96k072f40	7	18	burden	burden	NOUN
td96k072f40	7	19	.	.	PUNCT
td96k072f40	8	1	however	however	ADV
td96k072f40	8	2	,	,	PUNCT
td96k072f40	8	3	the	the	DET
td96k072f40	8	4	function	function	NOUN
td96k072f40	8	5	of	of	ADP
td96k072f40	8	6	these	these	DET
td96k072f40	8	7	exosome	exosome	NOUN
td96k072f40	8	8	is	be	AUX
td96k072f40	8	9	unclear	unclear	ADJ
td96k072f40	8	10	.	.	PUNCT
td96k072f40	9	1	endothelium	endothelium	PROPN
td96k072f40	9	2	,	,	PUNCT
td96k072f40	9	3	which	which	PRON
td96k072f40	9	4	can	can	AUX
td96k072f40	9	5	modulate	modulate	VERB
td96k072f40	9	6	immune	immune	ADJ
td96k072f40	9	7	responses	response	NOUN
td96k072f40	9	8	by	by	ADP
td96k072f40	9	9	regulating	regulate	VERB
td96k072f40	9	10	leukocyte	leukocyte	NOUN
td96k072f40	9	11	and	and	CCONJ
td96k072f40	9	12	antigen	antigen	NOUN
td96k072f40	9	13	traffic	traffic	NOUN
td96k072f40	9	14	,	,	PUNCT
td96k072f40	9	15	would	would	AUX
td96k072f40	9	16	be	be	AUX
td96k072f40	9	17	accessible	accessible	ADJ
td96k072f40	9	18	and	and	CCONJ
td96k072f40	9	19	responsive	responsive	ADJ
td96k072f40	9	20	to	to	ADP
td96k072f40	9	21	the	the	DET
td96k072f40	9	22	exosomes	exosome	NOUN
td96k072f40	9	23	in	in	ADP
td96k072f40	9	24	the	the	DET
td96k072f40	9	25	serum	serum	NOUN
td96k072f40	9	26	.	.	PUNCT
td96k072f40	10	1	we	we	PRON
td96k072f40	10	2	hypothesize	hypothesize	VERB
td96k072f40	10	3	that	that	SCONJ
td96k072f40	10	4	the	the	DET
td96k072f40	10	5	interactions	interaction	NOUN
td96k072f40	10	6	between	between	ADP
td96k072f40	10	7	exosomes	exosome	NOUN
td96k072f40	10	8	and	and	CCONJ
td96k072f40	10	9	endothelial	endothelial	ADJ
td96k072f40	10	10	cells	cell	NOUN
td96k072f40	10	11	would	would	AUX
td96k072f40	10	12	affect	affect	VERB
td96k072f40	10	13	the	the	DET
td96k072f40	10	14	immune	immune	ADJ
td96k072f40	10	15	response	response	NOUN
td96k072f40	10	16	.	.	PUNCT
td96k072f40	11	1	to	to	PART
td96k072f40	11	2	test	test	VERB
td96k072f40	11	3	this	this	DET
td96k072f40	11	4	hypothesis	hypothesis	NOUN
td96k072f40	11	5	,	,	PUNCT
td96k072f40	11	6	we	we	PRON
td96k072f40	11	7	treated	treat	VERB
td96k072f40	11	8	the	the	DET
td96k072f40	11	9	mouse	mouse	NOUN
td96k072f40	11	10	endothelial	endothelial	ADJ
td96k072f40	11	11	cell	cell	NOUN
td96k072f40	11	12	line	line	NOUN
td96k072f40	11	13	svec4	svec4	PROPN
td96k072f40	11	14	-	-	PUNCT
td96k072f40	11	15	10	10	NUM
td96k072f40	11	16	with	with	ADP
td96k072f40	11	17	exosomes	exosome	NOUN
td96k072f40	11	18	released	release	VERB
td96k072f40	11	19	from	from	ADP
td96k072f40	11	20	uninfected	uninfected	ADJ
td96k072f40	11	21	or	or	CCONJ
td96k072f40	11	22	m.tb	m.tb	NOUN
td96k072f40	11	23	-	-	PUNCT
td96k072f40	11	24	infected	infect	VERB
td96k072f40	11	25	macrophages	macrophage	NOUN
td96k072f40	11	26	.	.	PUNCT
td96k072f40	12	1	our	our	PRON
td96k072f40	12	2	results	result	NOUN
td96k072f40	12	3	indicate	indicate	VERB
td96k072f40	12	4	that	that	SCONJ
td96k072f40	12	5	endothelial	endothelial	ADJ
td96k072f40	12	6	cells	cell	NOUN
td96k072f40	12	7	treated	treat	VERB
td96k072f40	12	8	with	with	ADP
td96k072f40	12	9	exosomes	exosome	NOUN
td96k072f40	12	10	isolated	isolate	VERB
td96k072f40	12	11	from	from	ADP
td96k072f40	12	12	infected	infected	ADJ
td96k072f40	12	13	macrophages	macrophage	NOUN
td96k072f40	12	14	show	show	VERB
td96k072f40	12	15	increased	increase	VERB
td96k072f40	12	16	permeability	permeability	NOUN
td96k072f40	12	17	to	to	ADP
td96k072f40	12	18	dextran	dextran	NOUN
td96k072f40	12	19	and	and	CCONJ
td96k072f40	12	20	enhanced	enhanced	ADJ
td96k072f40	12	21	macrophage	macrophage	NOUN
td96k072f40	12	22	migration	migration	NOUN
td96k072f40	12	23	through	through	ADP
td96k072f40	12	24	the	the	DET
td96k072f40	12	25	endothelial	endothelial	ADJ
td96k072f40	12	26	cell	cell	NOUN
td96k072f40	12	27	monolayer	monolayer	NOUN
td96k072f40	12	28	.	.	PUNCT
td96k072f40	13	1	to	to	PART
td96k072f40	13	2	evaluate	evaluate	VERB
td96k072f40	13	3	the	the	DET
td96k072f40	13	4	effects	effect	NOUN
td96k072f40	13	5	more	more	ADV
td96k072f40	13	6	globally	globally	ADV
td96k072f40	13	7	,	,	PUNCT
td96k072f40	13	8	we	we	PRON
td96k072f40	13	9	sequenced	sequence	VERB
td96k072f40	13	10	the	the	DET
td96k072f40	13	11	transcriptome	transcriptome	NOUN
td96k072f40	13	12	of	of	ADP
td96k072f40	13	13	endothelial	endothelial	ADJ
td96k072f40	13	14	cells	cell	NOUN
td96k072f40	13	15	following	follow	VERB
td96k072f40	13	16	exosomes	exosome	NOUN
td96k072f40	13	17	treatment	treatment	NOUN
td96k072f40	13	18	.	.	PUNCT
td96k072f40	14	1	we	we	PRON
td96k072f40	14	2	found	find	VERB
td96k072f40	14	3	26	26	NUM
td96k072f40	14	4	genes	gene	NOUN
td96k072f40	14	5	were	be	AUX
td96k072f40	14	6	significantly	significantly	ADV
td96k072f40	14	7	up	up	ADV
td96k072f40	14	8	-	-	PUNCT
td96k072f40	14	9	regulated	regulate	VERB
td96k072f40	14	10	in	in	ADP
td96k072f40	14	11	endothelial	endothelial	ADJ
td96k072f40	14	12	cells	cell	NOUN
td96k072f40	14	13	treated	treat	VERB
td96k072f40	14	14	with	with	ADP
td96k072f40	14	15	exosomes	exosome	NOUN
td96k072f40	14	16	derived	derive	VERB
td96k072f40	14	17	from	from	ADP
td96k072f40	14	18	m.tb	m.tb	PROPN
td96k072f40	14	19	-	-	PUNCT
td96k072f40	14	20	infected	infect	VERB
td96k072f40	14	21	macrophages	macrophage	NOUN
td96k072f40	14	22	compared	compare	VERB
td96k072f40	14	23	to	to	ADP
td96k072f40	14	24	untreated	untreated	ADJ
td96k072f40	14	25	cells	cell	NOUN
td96k072f40	14	26	,	,	PUNCT
td96k072f40	14	27	of	of	ADP
td96k072f40	14	28	which	which	PRON
td96k072f40	14	29	12	12	NUM
td96k072f40	14	30	were	be	AUX
td96k072f40	14	31	also	also	ADV
td96k072f40	14	32	up	up	ADV
td96k072f40	14	33	-	-	PUNCT
td96k072f40	14	34	regulated	regulate	VERB
td96k072f40	14	35	when	when	SCONJ
td96k072f40	14	36	compared	compare	VERB
td96k072f40	14	37	to	to	ADP
td96k072f40	14	38	endothelial	endothelial	ADJ
td96k072f40	14	39	cells	cell	NOUN
td96k072f40	14	40	treated	treat	VERB
td96k072f40	14	41	with	with	ADP
td96k072f40	14	42	exosomes	exosome	NOUN
td96k072f40	14	43	derived	derive	VERB
td96k072f40	14	44	from	from	ADP
td96k072f40	14	45	non	non	ADJ
td96k072f40	14	46	-	-	ADJ
td96k072f40	14	47	infected	infected	ADJ
td96k072f40	14	48	macrophages	macrophage	NOUN
td96k072f40	14	49	(	(	PUNCT
td96k072f40	14	50	q	q	X
td96k072f40	14	51	value	value	PROPN
td96k072f40	14	52	&	&	CCONJ
td96k072f40	14	53	lt	lt	PROPN
td96k072f40	14	54	;	;	PUNCT
td96k072f40	14	55	0.05	0.05	NUM
td96k072f40	14	56	)	)	PUNCT
td96k072f40	14	57	.	.	PUNCT
td96k072f40	15	1	pathway	pathway	VERB
td96k072f40	15	2	analysis	analysis	NOUN
td96k072f40	15	3	(	(	PUNCT
td96k072f40	15	4	using	use	VERB
td96k072f40	15	5	genes	gene	NOUN
td96k072f40	15	6	which	which	PRON
td96k072f40	15	7	show	show	VERB
td96k072f40	15	8	&	&	CCONJ
td96k072f40	15	9	gt	gt	PROPN
td96k072f40	15	10	;	;	PUNCT
td96k072f40	15	11	2	2	NUM
td96k072f40	15	12	-	-	ADJ
td96k072f40	15	13	fold	fold	ADJ
td96k072f40	15	14	changes	change	NOUN
td96k072f40	15	15	in	in	ADP
td96k072f40	15	16	expression	expression	NOUN
td96k072f40	15	17	)	)	PUNCT
td96k072f40	15	18	indicates	indicate	VERB
td96k072f40	15	19	that	that	SCONJ
td96k072f40	15	20	several	several	ADJ
td96k072f40	15	21	immune	immune	ADJ
td96k072f40	15	22	response	response	NOUN
td96k072f40	15	23	-	-	PUNCT
td96k072f40	15	24	related	relate	VERB
td96k072f40	15	25	pathways	pathway	NOUN
td96k072f40	15	26	were	be	AUX
td96k072f40	15	27	up	up	ADV
td96k072f40	15	28	-	-	PUNCT
td96k072f40	15	29	regulated	regulate	VERB
td96k072f40	15	30	in	in	ADP
td96k072f40	15	31	endothelial	endothelial	ADJ
td96k072f40	15	32	cells	cell	NOUN
td96k072f40	15	33	following	follow	VERB
td96k072f40	15	34	exosome	exosome	PROPN
td96k072f40	15	35	treatment.transcriptome	treatment.transcriptome	PROPN
td96k072f40	15	36	studies	study	NOUN
td96k072f40	15	37	defined	define	VERB
td96k072f40	15	38	a	a	DET
td96k072f40	15	39	set	set	NOUN
td96k072f40	15	40	of	of	ADP
td96k072f40	15	41	genes	gene	NOUN
td96k072f40	15	42	involved	involve	VERB
td96k072f40	15	43	in	in	ADP
td96k072f40	15	44	adhesion	adhesion	NOUN
td96k072f40	15	45	and	and	CCONJ
td96k072f40	15	46	the	the	DET
td96k072f40	15	47	inflammatory	inflammatory	ADJ
td96k072f40	15	48	process	process	NOUN
td96k072f40	15	49	were	be	AUX
td96k072f40	15	50	significantly	significantly	ADV
td96k072f40	15	51	up	up	ADV
td96k072f40	15	52	-	-	PUNCT
td96k072f40	15	53	regulated	regulate	VERB
td96k072f40	15	54	in	in	ADP
td96k072f40	15	55	endothelial	endothelial	ADJ
td96k072f40	15	56	cells	cell	NOUN
td96k072f40	15	57	treated	treat	VERB
td96k072f40	15	58	with	with	ADP
td96k072f40	15	59	exosomes	exosome	NOUN
td96k072f40	15	60	from	from	ADP
td96k072f40	15	61	m.tb	m.tb	PROPN
td96k072f40	15	62	-	-	PUNCT
td96k072f40	15	63	infected	infect	VERB
td96k072f40	15	64	macrophages	macrophage	NOUN
td96k072f40	15	65	when	when	SCONJ
td96k072f40	15	66	compared	compare	VERB
td96k072f40	15	67	to	to	ADP
td96k072f40	15	68	untreated	untreated	ADJ
td96k072f40	15	69	cells	cell	NOUN
td96k072f40	15	70	or	or	CCONJ
td96k072f40	15	71	endothelial	endothelial	ADJ
td96k072f40	15	72	cells	cell	NOUN
td96k072f40	15	73	treated	treat	VERB
td96k072f40	15	74	with	with	ADP
td96k072f40	15	75	exosomes	exosome	NOUN
td96k072f40	15	76	from	from	ADP
td96k072f40	15	77	non	non	ADJ
td96k072f40	15	78	-	-	ADJ
td96k072f40	15	79	infected	infected	ADJ
td96k072f40	15	80	macrophages	macrophage	NOUN
td96k072f40	15	81	,	,	PUNCT
td96k072f40	15	82	including	include	VERB
td96k072f40	15	83	vcam1	vcam1	PROPN
td96k072f40	15	84	,	,	PUNCT
td96k072f40	15	85	tlr2	tlr2	NOUN
td96k072f40	15	86	and	and	CCONJ
td96k072f40	15	87	ccl2	ccl2	NOUN
td96k072f40	15	88	.	.	PUNCT
td96k072f40	16	1	these	these	DET
td96k072f40	16	2	results	result	NOUN
td96k072f40	16	3	were	be	AUX
td96k072f40	16	4	validated	validate	VERB
td96k072f40	16	5	by	by	ADP
td96k072f40	16	6	quantitative	quantitative	ADJ
td96k072f40	16	7	pcr	pcr	NOUN
td96k072f40	16	8	.	.	PUNCT
td96k072f40	17	1	the	the	DET
td96k072f40	17	2	upregulation	upregulation	NOUN
td96k072f40	17	3	of	of	ADP
td96k072f40	17	4	gene	gene	NOUN
td96k072f40	17	5	expression	expression	NOUN
td96k072f40	17	6	extended	extend	VERB
td96k072f40	17	7	to	to	ADP
td96k072f40	17	8	protein	protein	NOUN
td96k072f40	17	9	level	level	NOUN
td96k072f40	17	10	as	as	ADP
td96k072f40	17	11	flow	flow	NOUN
td96k072f40	17	12	cytometry	cytometry	NOUN
td96k072f40	17	13	data	datum	NOUN
td96k072f40	17	14	indicated	indicate	VERB
td96k072f40	17	15	enhanced	enhanced	ADJ
td96k072f40	17	16	expression	expression	NOUN
td96k072f40	17	17	of	of	ADP
td96k072f40	17	18	immune	immune	ADJ
td96k072f40	17	19	response	response	NOUN
td96k072f40	17	20	-	-	PUNCT
td96k072f40	17	21	related	relate	VERB
td96k072f40	17	22	proteins	protein	NOUN
td96k072f40	17	23	such	such	ADJ
td96k072f40	17	24	as	as	ADP
td96k072f40	17	25	vcam1	vcam1	PROPN
td96k072f40	17	26	,	,	PUNCT
td96k072f40	17	27	tlr2	tlr2	NOUN
td96k072f40	17	28	and	and	CCONJ
td96k072f40	17	29	ccl2	ccl2	NOUN
td96k072f40	17	30	,	,	PUNCT
td96k072f40	17	31	when	when	SCONJ
td96k072f40	17	32	endothelial	endothelial	ADJ
td96k072f40	17	33	cells	cell	NOUN
td96k072f40	17	34	were	be	AUX
td96k072f40	17	35	treated	treat	VERB
td96k072f40	17	36	with	with	ADP
td96k072f40	17	37	exosomes	exosome	NOUN
td96k072f40	17	38	derived	derive	VERB
td96k072f40	17	39	from	from	ADP
td96k072f40	17	40	m.tb	m.tb	PROPN
td96k072f40	17	41	-	-	PUNCT
td96k072f40	17	42	infected	infect	VERB
td96k072f40	17	43	macrophages	macrophage	NOUN
td96k072f40	17	44	compared	compare	VERB
td96k072f40	17	45	to	to	ADP
td96k072f40	17	46	cells	cell	NOUN
td96k072f40	17	47	treated	treat	VERB
td96k072f40	17	48	with	with	ADP
td96k072f40	17	49	exosomes	exosome	NOUN
td96k072f40	17	50	derived	derive	VERB
td96k072f40	17	51	from	from	ADP
td96k072f40	17	52	non	non	ADJ
td96k072f40	17	53	-	-	ADJ
td96k072f40	17	54	infected	infected	ADJ
td96k072f40	17	55	macrophages	macrophage	NOUN
td96k072f40	17	56	.	.	PUNCT
td96k072f40	18	1	moreover	moreover	ADV
td96k072f40	18	2	,	,	PUNCT
td96k072f40	18	3	immunofluorescence	immunofluorescence	NOUN
td96k072f40	18	4	microscopy	microscopy	NOUN
td96k072f40	18	5	data	datum	NOUN
td96k072f40	18	6	indicated	indicate	VERB
td96k072f40	18	7	that	that	SCONJ
td96k072f40	18	8	the	the	DET
td96k072f40	18	9	nf	nf	PROPN
td96k072f40	18	10	-	-	PUNCT
td96k072f40	18	11	kb	kb	PROPN
td96k072f40	18	12	pathway	pathway	NOUN
td96k072f40	18	13	was	be	AUX
td96k072f40	18	14	activated	activate	VERB
td96k072f40	18	15	in	in	ADP
td96k072f40	18	16	endothelial	endothelial	ADJ
td96k072f40	18	17	cells	cell	NOUN
td96k072f40	18	18	treated	treat	VERB
td96k072f40	18	19	with	with	ADP
td96k072f40	18	20	exosomes	exosome	NOUN
td96k072f40	18	21	released	release	VERB
td96k072f40	18	22	from	from	ADP
td96k072f40	18	23	m.tb	m.tb	PROPN
td96k072f40	18	24	-	-	PUNCT
td96k072f40	18	25	infected	infect	VERB
td96k072f40	18	26	cells.to	cells.to	NUM
td96k072f40	18	27	test	test	NOUN
td96k072f40	18	28	the	the	DET
td96k072f40	18	29	function	function	NOUN
td96k072f40	18	30	of	of	ADP
td96k072f40	18	31	the	the	DET
td96k072f40	18	32	in	in	ADP
td96k072f40	18	33	vivo	vivo	NOUN
td96k072f40	18	34	-	-	PUNCT
td96k072f40	18	35	derived	derive	VERB
td96k072f40	18	36	exosomes	exosome	NOUN
td96k072f40	18	37	,	,	PUNCT
td96k072f40	18	38	endothelial	endothelial	ADJ
td96k072f40	18	39	cells	cell	NOUN
td96k072f40	18	40	were	be	AUX
td96k072f40	18	41	also	also	ADV
td96k072f40	18	42	treated	treat	VERB
td96k072f40	18	43	with	with	ADP
td96k072f40	18	44	exosomes	exosome	NOUN
td96k072f40	18	45	isolated	isolate	VERB
td96k072f40	18	46	from	from	ADP
td96k072f40	18	47	the	the	DET
td96k072f40	18	48	serum	serum	NOUN
td96k072f40	18	49	of	of	ADP
td96k072f40	18	50	m.tb	m.tb	PROPN
td96k072f40	18	51	-	-	PUNCT
td96k072f40	18	52	infected	infect	VERB
td96k072f40	18	53	mice	mouse	NOUN
td96k072f40	18	54	.	.	PUNCT
td96k072f40	19	1	interestingly	interestingly	ADV
td96k072f40	19	2	,	,	PUNCT
td96k072f40	19	3	exosomes	exosome	NOUN
td96k072f40	19	4	isolated	isolate	VERB
td96k072f40	19	5	14	14	NUM
td96k072f40	19	6	days	day	NOUN
td96k072f40	19	7	but	but	CCONJ
td96k072f40	19	8	not	not	PART
td96k072f40	19	9	7	7	NUM
td96k072f40	19	10	or	or	CCONJ
td96k072f40	19	11	21	21	NUM
td96k072f40	19	12	days	day	NOUN
td96k072f40	19	13	post	post	ADJ
td96k072f40	19	14	-	-	NOUN
td96k072f40	19	15	infection	infection	NOUN
td96k072f40	19	16	showed	show	VERB
td96k072f40	19	17	a	a	DET
td96k072f40	19	18	similar	similar	ADJ
td96k072f40	19	19	ability	ability	NOUN
td96k072f40	19	20	to	to	PART
td96k072f40	19	21	induce	induce	VERB
td96k072f40	19	22	endothelial	endothelial	ADJ
td96k072f40	19	23	cell	cell	NOUN
td96k072f40	19	24	activation	activation	NOUN
td96k072f40	19	25	.	.	PUNCT
td96k072f40	20	1	we	we	PRON
td96k072f40	20	2	found	find	VERB
td96k072f40	20	3	that	that	SCONJ
td96k072f40	20	4	the	the	DET
td96k072f40	20	5	same	same	ADJ
td96k072f40	20	6	set	set	NOUN
td96k072f40	20	7	of	of	ADP
td96k072f40	20	8	genes	gene	NOUN
td96k072f40	20	9	that	that	PRON
td96k072f40	20	10	were	be	AUX
td96k072f40	20	11	upregulated	upregulate	VERB
td96k072f40	20	12	in	in	ADP
td96k072f40	20	13	our	our	PRON
td96k072f40	20	14	in	in	X
td96k072f40	20	15	vitro	vitro	X
td96k072f40	20	16	study	study	NOUN
td96k072f40	20	17	were	be	AUX
td96k072f40	20	18	also	also	ADV
td96k072f40	20	19	increased	increase	VERB
td96k072f40	20	20	at	at	ADV
td96k072f40	20	21	least	least	ADV
td96k072f40	20	22	2	2	NUM
td96k072f40	20	23	fold	fold	NOUN
td96k072f40	20	24	in	in	ADP
td96k072f40	20	25	endothelial	endothelial	ADJ
td96k072f40	20	26	cells	cell	NOUN
td96k072f40	20	27	when	when	SCONJ
td96k072f40	20	28	treated	treat	VERB
td96k072f40	20	29	with	with	ADP
td96k072f40	20	30	exosomes	exosome	NOUN
td96k072f40	20	31	derived	derive	VERB
td96k072f40	20	32	from	from	ADP
td96k072f40	20	33	mice	mouse	NOUN
td96k072f40	20	34	14	14	NUM
td96k072f40	20	35	days	day	NOUN
td96k072f40	20	36	post	post	VERB
td96k072f40	20	37	m.tb	m.tb	NOUN
td96k072f40	20	38	infection	infection	NOUN
td96k072f40	20	39	.	.	PUNCT
td96k072f40	21	1	this	this	DET
td96k072f40	21	2	differential	differential	ADJ
td96k072f40	21	3	expression	expression	NOUN
td96k072f40	21	4	extended	extend	VERB
td96k072f40	21	5	to	to	ADP
td96k072f40	21	6	the	the	DET
td96k072f40	21	7	protein	protein	NOUN
td96k072f40	21	8	level	level	NOUN
td96k072f40	21	9	as	as	SCONJ
td96k072f40	21	10	ccl2	ccl2	NOUN
td96k072f40	21	11	was	be	AUX
td96k072f40	21	12	expressed	express	VERB
td96k072f40	21	13	at	at	ADP
td96k072f40	21	14	the	the	DET
td96k072f40	21	15	highest	high	ADJ
td96k072f40	21	16	level	level	NOUN
td96k072f40	21	17	when	when	SCONJ
td96k072f40	21	18	endothelial	endothelial	ADJ
td96k072f40	21	19	cells	cell	NOUN
td96k072f40	21	20	were	be	AUX
td96k072f40	21	21	treated	treat	VERB
td96k072f40	21	22	with	with	ADP
td96k072f40	21	23	serum	serum	NOUN
td96k072f40	21	24	exosomes	exosome	NOUN
td96k072f40	21	25	isolated	isolate	VERB
td96k072f40	21	26	14	14	NUM
td96k072f40	21	27	days	day	NOUN
td96k072f40	21	28	post	post	NOUN
td96k072f40	21	29	infection	infection	NOUN
td96k072f40	21	30	.	.	PUNCT
td96k072f40	22	1	simillarly	simillarly	ADV
td96k072f40	22	2	,	,	PUNCT
td96k072f40	22	3	there	there	PRON
td96k072f40	22	4	was	be	VERB
td96k072f40	22	5	enhanced	enhance	VERB
td96k072f40	22	6	macrophage	macrophage	NOUN
td96k072f40	22	7	migration	migration	NOUN
td96k072f40	22	8	through	through	ADP
td96k072f40	22	9	the	the	DET
td96k072f40	22	10	monolayer	monolayer	NOUN
td96k072f40	22	11	when	when	SCONJ
td96k072f40	22	12	the	the	DET
td96k072f40	22	13	endothelial	endothelial	ADJ
td96k072f40	22	14	cells	cell	NOUN
td96k072f40	22	15	were	be	AUX
td96k072f40	22	16	treated	treat	VERB
td96k072f40	22	17	with	with	ADP
td96k072f40	22	18	these	these	DET
td96k072f40	22	19	serum	serum	NOUN
td96k072f40	22	20	-	-	PUNCT
td96k072f40	22	21	derived	derive	VERB
td96k072f40	22	22	exosomes	exosome	NOUN
td96k072f40	22	23	.	.	PUNCT
td96k072f40	23	1	these	these	DET
td96k072f40	23	2	results	result	NOUN
td96k072f40	23	3	suggest	suggest	VERB
td96k072f40	23	4	a	a	DET
td96k072f40	23	5	change	change	NOUN
td96k072f40	23	6	in	in	ADP
td96k072f40	23	7	exosome	exosome	NOUN
td96k072f40	23	8	composition	composition	NOUN
td96k072f40	23	9	and	and	CCONJ
td96k072f40	23	10	function	function	NOUN
td96k072f40	23	11	during	during	ADP
td96k072f40	23	12	the	the	DET
td96k072f40	23	13	course	course	NOUN
td96k072f40	23	14	of	of	ADP
td96k072f40	23	15	an	an	DET
td96k072f40	23	16	m.tb	m.tb	NOUN
td96k072f40	23	17	infection.in	infection.in	NUM
td96k072f40	23	18	summary	summary	NOUN
td96k072f40	23	19	,	,	PUNCT
td96k072f40	23	20	our	our	PRON
td96k072f40	23	21	data	datum	NOUN
td96k072f40	23	22	suggest	suggest	VERB
td96k072f40	23	23	that	that	SCONJ
td96k072f40	23	24	exosomes	exosome	NOUN
td96k072f40	23	25	can	can	AUX
td96k072f40	23	26	activate	activate	VERB
td96k072f40	23	27	endothelial	endothelial	ADJ
td96k072f40	23	28	cells	cell	NOUN
td96k072f40	23	29	and	and	CCONJ
td96k072f40	23	30	thus	thus	ADV
td96k072f40	23	31	may	may	AUX
td96k072f40	23	32	play	play	VERB
td96k072f40	23	33	an	an	DET
td96k072f40	23	34	important	important	ADJ
td96k072f40	23	35	role	role	NOUN
td96k072f40	23	36	in	in	ADP
td96k072f40	23	37	modulating	modulate	VERB
td96k072f40	23	38	the	the	DET
td96k072f40	23	39	host	host	NOUN
td96k072f40	23	40	immune	immune	ADJ
td96k072f40	23	41	response	response	NOUN
td96k072f40	23	42	during	during	ADP
td96k072f40	23	43	a	a	DET
td96k072f40	23	44	mycobacterial	mycobacterial	ADJ
td96k072f40	23	45	infection	infection	NOUN
td96k072f40	23	46	.	.	PUNCT