id	sid	tid	token	lemma	pos
sj13902268m	1	1	in	in	ADP
sj13902268m	1	2	the	the	DET
sj13902268m	1	3	past	past	ADJ
sj13902268m	1	4	few	few	ADJ
sj13902268m	1	5	years	year	NOUN
sj13902268m	1	6	,	,	PUNCT
sj13902268m	1	7	several	several	ADJ
sj13902268m	1	8	functional	functional	ADJ
sj13902268m	1	9	site	site	NOUN
sj13902268m	1	10	prediction	prediction	NOUN
sj13902268m	1	11	methods	method	NOUN
sj13902268m	1	12	have	have	AUX
sj13902268m	1	13	been	be	AUX
sj13902268m	1	14	introduced	introduce	VERB
sj13902268m	1	15	that	that	PRON
sj13902268m	1	16	aim	aim	VERB
sj13902268m	1	17	to	to	PART
sj13902268m	1	18	predict	predict	VERB
sj13902268m	1	19	the	the	DET
sj13902268m	1	20	biologically	biologically	ADV
sj13902268m	1	21	relevant	relevant	ADJ
sj13902268m	1	22	amino	amino	ADJ
sj13902268m	1	23	acids	acid	NOUN
sj13902268m	1	24	in	in	ADP
sj13902268m	1	25	proteins	protein	NOUN
sj13902268m	1	26	based	base	VERB
sj13902268m	1	27	purely	purely	ADV
sj13902268m	1	28	off	off	ADP
sj13902268m	1	29	of	of	ADP
sj13902268m	1	30	a	a	DET
sj13902268m	1	31	multiple	multiple	ADJ
sj13902268m	1	32	sequence	sequence	NOUN
sj13902268m	1	33	alignment	alignment	NOUN
sj13902268m	1	34	.	.	PUNCT
sj13902268m	2	1	these	these	DET
sj13902268m	2	2	methods	method	NOUN
sj13902268m	2	3	utilize	utilize	VERB
sj13902268m	2	4	a	a	DET
sj13902268m	2	5	variety	variety	NOUN
sj13902268m	2	6	of	of	ADP
sj13902268m	2	7	approaches	approach	NOUN
sj13902268m	2	8	including	include	VERB
sj13902268m	2	9	conservation	conservation	NOUN
sj13902268m	2	10	,	,	PUNCT
sj13902268m	2	11	divergence	divergence	NOUN
sj13902268m	2	12	,	,	PUNCT
sj13902268m	2	13	and	and	CCONJ
sj13902268m	2	14	perturbation	perturbation	NOUN
sj13902268m	2	15	to	to	PART
sj13902268m	2	16	identify	identify	VERB
sj13902268m	2	17	the	the	DET
sj13902268m	2	18	functionally	functionally	ADV
sj13902268m	2	19	important	important	ADJ
sj13902268m	2	20	amino	amino	NOUN
sj13902268m	2	21	acid	acid	NOUN
sj13902268m	2	22	positions	position	NOUN
sj13902268m	2	23	(	(	PUNCT
sj13902268m	2	24	primary	primary	ADJ
sj13902268m	2	25	sequence	sequence	NOUN
sj13902268m	2	26	or	or	CCONJ
sj13902268m	2	27	3d	3d	NOUN
sj13902268m	2	28	structure	structure	NOUN
sj13902268m	2	29	)	)	PUNCT
sj13902268m	2	30	within	within	ADP
sj13902268m	2	31	the	the	DET
sj13902268m	2	32	protein	protein	NOUN
sj13902268m	2	33	sequence	sequence	NOUN
sj13902268m	2	34	.	.	PUNCT
sj13902268m	3	1	yet	yet	ADV
sj13902268m	3	2	,	,	PUNCT
sj13902268m	3	3	the	the	DET
sj13902268m	3	4	question	question	NOUN
sj13902268m	3	5	remains	remain	VERB
sj13902268m	3	6	if	if	SCONJ
sj13902268m	3	7	these	these	DET
sj13902268m	3	8	methods	method	NOUN
sj13902268m	3	9	accurately	accurately	ADV
sj13902268m	3	10	predict	predict	VERB
sj13902268m	3	11	the	the	DET
sj13902268m	3	12	functionally	functionally	ADV
sj13902268m	3	13	important	important	ADJ
sj13902268m	3	14	residues	residue	NOUN
sj13902268m	3	15	within	within	ADP
sj13902268m	3	16	a	a	DET
sj13902268m	3	17	protein	protein	NOUN
sj13902268m	3	18	found	find	VERB
sj13902268m	3	19	experimentally	experimentally	ADV
sj13902268m	3	20	.	.	PUNCT
sj13902268m	4	1	this	this	DET
sj13902268m	4	2	dissertation	dissertation	NOUN
sj13902268m	4	3	investigates	investigate	VERB
sj13902268m	4	4	the	the	DET
sj13902268m	4	5	capability	capability	NOUN
sj13902268m	4	6	of	of	ADP
sj13902268m	4	7	the	the	DET
sj13902268m	4	8	bioinformatic	bioinformatic	ADJ
sj13902268m	4	9	functional	functional	ADJ
sj13902268m	4	10	site	site	NOUN
sj13902268m	4	11	prediction	prediction	NOUN
sj13902268m	4	12	methods	method	NOUN
sj13902268m	4	13	.	.	PUNCT
sj13902268m	5	1	residues	residue	NOUN
sj13902268m	5	2	known	know	VERB
sj13902268m	5	3	to	to	PART
sj13902268m	5	4	participate	participate	VERB
sj13902268m	5	5	in	in	ADP
sj13902268m	5	6	conformational	conformational	ADJ
sj13902268m	5	7	dynamics	dynamic	NOUN
sj13902268m	5	8	associated	associate	VERB
sj13902268m	5	9	with	with	ADP
sj13902268m	5	10	substrate	substrate	NOUN
sj13902268m	5	11	binding	bind	VERB
sj13902268m	5	12	,	,	PUNCT
sj13902268m	5	13	as	as	SCONJ
sj13902268m	5	14	observed	observed	ADJ
sj13902268m	5	15	experimentally	experimentally	NOUN
sj13902268m	5	16	by	by	ADP
sj13902268m	5	17	nuclear	nuclear	ADJ
sj13902268m	5	18	magnetic	magnetic	ADJ
sj13902268m	5	19	resonance	resonance	NOUN
sj13902268m	5	20	(	(	PUNCT
sj13902268m	5	21	nmr	nmr	NOUN
sj13902268m	5	22	)	)	PUNCT
sj13902268m	5	23	spectroscopy	spectroscopy	NOUN
sj13902268m	5	24	,	,	PUNCT
sj13902268m	5	25	are	be	AUX
sj13902268m	5	26	compared	compare	VERB
sj13902268m	5	27	to	to	ADP
sj13902268m	5	28	those	those	DET
sj13902268m	5	29	residues	residue	NOUN
sj13902268m	5	30	highlighted	highlight	VERB
sj13902268m	5	31	by	by	ADP
sj13902268m	5	32	the	the	DET
sj13902268m	5	33	prediction	prediction	NOUN
sj13902268m	5	34	methods	method	NOUN
sj13902268m	5	35	.	.	PUNCT
sj13902268m	6	1	the	the	DET
sj13902268m	6	2	comparison	comparison	NOUN
sj13902268m	6	3	of	of	ADP
sj13902268m	6	4	results	result	NOUN
sj13902268m	6	5	given	give	VERB
sj13902268m	6	6	above	above	ADV
sj13902268m	6	7	will	will	AUX
sj13902268m	6	8	provide	provide	VERB
sj13902268m	6	9	insight	insight	NOUN
sj13902268m	6	10	into	into	ADP
sj13902268m	6	11	the	the	DET
sj13902268m	6	12	protein	protein	NOUN
sj13902268m	6	13	evolution	evolution	NOUN
sj13902268m	6	14	-	-	PUNCT
sj13902268m	6	15	dynamics	dynamics	NOUN
sj13902268m	6	16	-	-	PUNCT
sj13902268m	6	17	function	function	NOUN
sj13902268m	6	18	relationship	relationship	NOUN
sj13902268m	6	19	.	.	PUNCT
sj13902268m	7	1	a	a	DET
sj13902268m	7	2	test	test	NOUN
sj13902268m	7	3	of	of	ADP
sj13902268m	7	4	how	how	SCONJ
sj13902268m	7	5	well	well	ADV
sj13902268m	7	6	the	the	DET
sj13902268m	7	7	current	current	ADJ
sj13902268m	7	8	prediction	prediction	NOUN
sj13902268m	7	9	methods	method	NOUN
sj13902268m	7	10	perform	perform	VERB
sj13902268m	7	11	at	at	ADP
sj13902268m	7	12	selecting	select	VERB
sj13902268m	7	13	the	the	DET
sj13902268m	7	14	functionally	functionally	ADV
sj13902268m	7	15	relevant	relevant	ADJ
sj13902268m	7	16	residues	residue	NOUN
sj13902268m	7	17	is	be	AUX
sj13902268m	7	18	presented	present	VERB
sj13902268m	7	19	herein	herein	ADV
sj13902268m	7	20	.	.	PUNCT
sj13902268m	8	1	specifically	specifically	ADV
sj13902268m	8	2	,	,	PUNCT
sj13902268m	8	3	because	because	SCONJ
sj13902268m	8	4	dynamics	dynamic	NOUN
sj13902268m	8	5	are	be	AUX
sj13902268m	8	6	encoded	encode	VERB
sj13902268m	8	7	in	in	ADP
sj13902268m	8	8	the	the	DET
sj13902268m	8	9	protein	protein	NOUN
sj13902268m	8	10	sequence	sequence	NOUN
sj13902268m	8	11	and	and	CCONJ
sj13902268m	8	12	are	be	AUX
sj13902268m	8	13	required	require	VERB
sj13902268m	8	14	for	for	ADP
sj13902268m	8	15	function	function	NOUN
sj13902268m	8	16	,	,	PUNCT
sj13902268m	8	17	then	then	ADV
sj13902268m	8	18	a	a	DET
sj13902268m	8	19	mutation	mutation	NOUN
sj13902268m	8	20	of	of	ADP
sj13902268m	8	21	a	a	DET
sj13902268m	8	22	functionally	functionally	ADV
sj13902268m	8	23	important	important	ADJ
sj13902268m	8	24	position	position	NOUN
sj13902268m	8	25	will	will	AUX
sj13902268m	8	26	alter	alter	VERB
sj13902268m	8	27	both	both	CCONJ
sj13902268m	8	28	the	the	DET
sj13902268m	8	29	internal	internal	ADJ
sj13902268m	8	30	dynamics	dynamic	NOUN
sj13902268m	8	31	and	and	CCONJ
sj13902268m	8	32	its	its	PRON
sj13902268m	8	33	activity	activity	NOUN
sj13902268m	8	34	.	.	PUNCT
sj13902268m	9	1	the	the	DET
sj13902268m	9	2	time	time	NOUN
sj13902268m	9	3	scales	scale	NOUN
sj13902268m	9	4	for	for	ADP
sj13902268m	9	5	such	such	ADJ
sj13902268m	9	6	motions	motion	NOUN
sj13902268m	9	7	can	can	AUX
sj13902268m	9	8	be	be	AUX
sj13902268m	9	9	on	on	ADP
sj13902268m	9	10	the	the	DET
sj13902268m	9	11	order	order	NOUN
sj13902268m	9	12	of	of	ADP
sj13902268m	9	13	slow	slow	ADJ
sj13902268m	9	14	(	(	PUNCT
sj13902268m	9	15	&	&	CCONJ
sj13902268m	9	16	#	#	SYM
sj13902268m	9	17	956;s	956;s	NUM
sj13902268m	9	18	-	-	PUNCT
sj13902268m	9	19	ms	ms	PROPN
sj13902268m	9	20	)	)	PUNCT
sj13902268m	9	21	to	to	PART
sj13902268m	9	22	fast	fast	VERB
sj13902268m	9	23	(	(	PUNCT
sj13902268m	9	24	ps	ps	NOUN
sj13902268m	9	25	-	-	PUNCT
sj13902268m	9	26	ns	ns	PROPN
sj13902268m	9	27	)	)	PUNCT
sj13902268m	9	28	motions	motion	NOUN
sj13902268m	9	29	.	.	PUNCT
sj13902268m	10	1	nuclear	nuclear	ADJ
sj13902268m	10	2	magnetic	magnetic	ADJ
sj13902268m	10	3	resonance	resonance	NOUN
sj13902268m	10	4	(	(	PUNCT
sj13902268m	10	5	nmr	nmr	NOUN
sj13902268m	10	6	)	)	PUNCT
sj13902268m	10	7	is	be	AUX
sj13902268m	10	8	a	a	DET
sj13902268m	10	9	non	non	ADJ
sj13902268m	10	10	-	-	ADJ
sj13902268m	10	11	invasive	invasive	ADJ
sj13902268m	10	12	technique	technique	NOUN
sj13902268m	10	13	which	which	PRON
sj13902268m	10	14	probes	probe	VERB
sj13902268m	10	15	such	such	ADJ
sj13902268m	10	16	dynamics	dynamic	NOUN
sj13902268m	10	17	relevant	relevant	ADJ
sj13902268m	10	18	for	for	ADP
sj13902268m	10	19	function	function	NOUN
sj13902268m	10	20	.	.	PUNCT
sj13902268m	11	1	overlap	overlap	NOUN
sj13902268m	11	2	exists	exist	VERB
sj13902268m	11	3	between	between	ADP
sj13902268m	11	4	the	the	DET
sj13902268m	11	5	bioinformatic	bioinformatic	ADJ
sj13902268m	11	6	prediction	prediction	NOUN
sj13902268m	11	7	methods	method	NOUN
sj13902268m	11	8	and	and	CCONJ
sj13902268m	11	9	the	the	DET
sj13902268m	11	10	experimental	experimental	ADJ
sj13902268m	11	11	data	datum	NOUN
sj13902268m	11	12	for	for	ADP
sj13902268m	11	13	many	many	ADJ
sj13902268m	11	14	of	of	ADP
sj13902268m	11	15	the	the	DET
sj13902268m	11	16	residues	residue	NOUN
sj13902268m	11	17	used	use	VERB
sj13902268m	11	18	in	in	ADP
sj13902268m	11	19	the	the	DET
sj13902268m	11	20	model	model	NOUN
sj13902268m	11	21	system	system	NOUN
sj13902268m	11	22	,	,	PUNCT
sj13902268m	11	23	human	human	ADJ
sj13902268m	11	24	pin1	pin1	NOUN
sj13902268m	11	25	.	.	PUNCT
sj13902268m	12	1	many	many	ADJ
sj13902268m	12	2	of	of	ADP
sj13902268m	12	3	the	the	DET
sj13902268m	12	4	residues	residue	NOUN
sj13902268m	12	5	identified	identify	VERB
sj13902268m	12	6	experimentally	experimentally	ADV
sj13902268m	12	7	by	by	ADP
sj13902268m	12	8	nmr	nmr	NOUN
sj13902268m	12	9	to	to	PART
sj13902268m	12	10	have	have	VERB
sj13902268m	12	11	conformational	conformational	ADJ
sj13902268m	12	12	dynamics	dynamic	NOUN
sj13902268m	12	13	due	due	ADP
sj13902268m	12	14	to	to	ADP
sj13902268m	12	15	substrate	substrate	NOUN
sj13902268m	12	16	binding	bind	VERB
sj13902268m	12	17	are	be	AUX
sj13902268m	12	18	the	the	DET
sj13902268m	12	19	same	same	ADJ
sj13902268m	12	20	residues	residue	NOUN
sj13902268m	12	21	predicted	predict	VERB
sj13902268m	12	22	to	to	PART
sj13902268m	12	23	be	be	AUX
sj13902268m	12	24	functionally	functionally	ADV
sj13902268m	12	25	relevant	relevant	ADJ
sj13902268m	12	26	from	from	ADP
sj13902268m	12	27	the	the	DET
sj13902268m	12	28	functional	functional	ADJ
sj13902268m	12	29	site	site	NOUN
sj13902268m	12	30	prediction	prediction	NOUN
sj13902268m	12	31	methods	method	NOUN
sj13902268m	12	32	.	.	PUNCT
sj13902268m	13	1	for	for	ADP
sj13902268m	13	2	a	a	DET
sj13902268m	13	3	select	select	ADJ
sj13902268m	13	4	few	few	ADJ
sj13902268m	13	5	amino	amino	NOUN
sj13902268m	13	6	acid	acid	NOUN
sj13902268m	13	7	positions	position	NOUN
sj13902268m	13	8	,	,	PUNCT
sj13902268m	13	9	the	the	DET
sj13902268m	13	10	agreement	agreement	NOUN
sj13902268m	13	11	between	between	ADP
sj13902268m	13	12	the	the	DET
sj13902268m	13	13	two	two	NUM
sj13902268m	13	14	approaches	approach	NOUN
sj13902268m	13	15	is	be	AUX
sj13902268m	13	16	not	not	PART
sj13902268m	13	17	perfect	perfect	ADJ
sj13902268m	13	18	.	.	PUNCT
sj13902268m	14	1	what	what	PRON
sj13902268m	14	2	follows	follow	VERB
sj13902268m	14	3	in	in	ADP
sj13902268m	14	4	this	this	DET
sj13902268m	14	5	thesis	thesis	NOUN
sj13902268m	14	6	is	be	AUX
sj13902268m	14	7	a	a	DET
sj13902268m	14	8	discussion	discussion	NOUN
sj13902268m	14	9	on	on	ADP
sj13902268m	14	10	two	two	NUM
sj13902268m	14	11	mutations	mutation	NOUN
sj13902268m	14	12	of	of	ADP
sj13902268m	14	13	pin1	pin1	NOUN
sj13902268m	14	14	.	.	PUNCT
sj13902268m	15	1	for	for	ADP
sj13902268m	15	2	the	the	DET
sj13902268m	15	3	one	one	NUM
sj13902268m	15	4	mutation	mutation	NOUN
sj13902268m	15	5	,	,	PUNCT
sj13902268m	15	6	m130a	m130a	PROPN
sj13902268m	15	7	,	,	PUNCT
sj13902268m	15	8	agreement	agreement	NOUN
sj13902268m	15	9	exists	exist	VERB
sj13902268m	15	10	between	between	ADP
sj13902268m	15	11	the	the	DET
sj13902268m	15	12	functional	functional	ADJ
sj13902268m	15	13	site	site	NOUN
sj13902268m	15	14	prediction	prediction	NOUN
sj13902268m	15	15	methods	method	NOUN
sj13902268m	15	16	and	and	CCONJ
sj13902268m	15	17	experimental	experimental	ADJ
sj13902268m	15	18	intrinsic	intrinsic	ADJ
sj13902268m	15	19	dynamics	dynamic	NOUN
sj13902268m	15	20	.	.	PUNCT
sj13902268m	16	1	in	in	ADP
sj13902268m	16	2	the	the	DET
sj13902268m	16	3	other	other	ADJ
sj13902268m	16	4	,	,	PUNCT
sj13902268m	16	5	i28a	i28a	PROPN
sj13902268m	16	6	,	,	PUNCT
sj13902268m	16	7	the	the	DET
sj13902268m	16	8	agreement	agreement	NOUN
sj13902268m	16	9	between	between	ADP
sj13902268m	16	10	the	the	DET
sj13902268m	16	11	two	two	NUM
sj13902268m	16	12	methods	method	NOUN
sj13902268m	16	13	fails	fail	VERB
sj13902268m	16	14	.	.	PUNCT