id sid tid token lemma pos s4655d8938t 1 1 the the DET s4655d8938t 1 2 cloning cloning NOUN s4655d8938t 1 3 and and CCONJ s4655d8938t 1 4 characterization characterization NOUN s4655d8938t 1 5 of of ADP s4655d8938t 1 6 two two NUM s4655d8938t 1 7 zebrafish zebrafish NOUN s4655d8938t 1 8 genes gene NOUN s4655d8938t 1 9 are be AUX s4655d8938t 1 10 described describe VERB s4655d8938t 1 11 here here ADV s4655d8938t 1 12 : : PUNCT s4655d8938t 1 13 pitx3 pitx3 PROPN s4655d8938t 1 14 , , PUNCT s4655d8938t 1 15 a a DET s4655d8938t 1 16 bicoid bicoid ADJ s4655d8938t 1 17 - - PUNCT s4655d8938t 1 18 like like ADJ s4655d8938t 1 19 homeodomain homeodomain NOUN s4655d8938t 1 20 transcription transcription NOUN s4655d8938t 1 21 factor factor NOUN s4655d8938t 1 22 , , PUNCT s4655d8938t 1 23 and and CCONJ s4655d8938t 1 24 foxe3 foxe3 PROPN s4655d8938t 1 25 , , PUNCT s4655d8938t 1 26 a a DET s4655d8938t 1 27 winged winged ADJ s4655d8938t 1 28 helix helix NOUN s4655d8938t 1 29 / / SYM s4655d8938t 1 30 forkhead forkhead NOUN s4655d8938t 1 31 domain domain NOUN s4655d8938t 1 32 transcription transcription NOUN s4655d8938t 1 33 factor factor NOUN s4655d8938t 1 34 . . PUNCT s4655d8938t 2 1 human human ADJ s4655d8938t 2 2 homologs homolog NOUN s4655d8938t 2 3 of of ADP s4655d8938t 2 4 these these DET s4655d8938t 2 5 two two NUM s4655d8938t 2 6 genes gene NOUN s4655d8938t 2 7 have have AUX s4655d8938t 2 8 been be AUX s4655d8938t 2 9 associated associate VERB s4655d8938t 2 10 with with ADP s4655d8938t 2 11 various various ADJ s4655d8938t 2 12 forms form NOUN s4655d8938t 2 13 of of ADP s4655d8938t 2 14 anterior anterior ADJ s4655d8938t 2 15 segment segment NOUN s4655d8938t 2 16 dysgenesis dysgenesis NOUN s4655d8938t 2 17 , , PUNCT s4655d8938t 2 18 congenital congenital ADJ s4655d8938t 2 19 cataracts cataract NOUN s4655d8938t 2 20 and and CCONJ s4655d8938t 2 21 glaucoma glaucoma NOUN s4655d8938t 2 22 . . PUNCT s4655d8938t 3 1 the the DET s4655d8938t 3 2 zebrafish zebrafish NOUN s4655d8938t 3 3 pitx3 pitx3 PROPN s4655d8938t 3 4 gene gene NOUN s4655d8938t 3 5 consists consist VERB s4655d8938t 3 6 four four NUM s4655d8938t 3 7 exons exon NOUN s4655d8938t 3 8 , , PUNCT s4655d8938t 3 9 which which PRON s4655d8938t 3 10 is be AUX s4655d8938t 3 11 similar similar ADJ s4655d8938t 3 12 to to ADP s4655d8938t 3 13 the the DET s4655d8938t 3 14 genomic genomic ADJ s4655d8938t 3 15 organization organization NOUN s4655d8938t 3 16 of of ADP s4655d8938t 3 17 other other ADJ s4655d8938t 3 18 vertebrate vertebrate NOUN s4655d8938t 3 19 pitx3 pitx3 NOUN s4655d8938t 3 20 genes gene NOUN s4655d8938t 3 21 . . PUNCT s4655d8938t 4 1 it it PRON s4655d8938t 4 2 encodes encode VERB s4655d8938t 4 3 a a DET s4655d8938t 4 4 protein protein NOUN s4655d8938t 4 5 of of ADP s4655d8938t 4 6 293 293 NUM s4655d8938t 4 7 amino amino NOUN s4655d8938t 4 8 acids acid NOUN s4655d8938t 4 9 possessing possess VERB s4655d8938t 4 10 63 63 NUM s4655d8938t 4 11 % % NOUN s4655d8938t 4 12 amino amino NOUN s4655d8938t 4 13 acid acid NOUN s4655d8938t 4 14 identity identity NOUN s4655d8938t 4 15 with with ADP s4655d8938t 4 16 the the DET s4655d8938t 4 17 human human ADJ s4655d8938t 4 18 pitx3 pitx3 PROPN s4655d8938t 4 19 protein protein NOUN s4655d8938t 4 20 . . PUNCT s4655d8938t 5 1 zebrafish zebrafish NOUN s4655d8938t 5 2 pitx3 pitx3 PROPN s4655d8938t 5 3 expression expression NOUN s4655d8938t 5 4 was be AUX s4655d8938t 5 5 first first ADV s4655d8938t 5 6 detected detect VERB s4655d8938t 5 7 at at ADP s4655d8938t 5 8 24 24 NUM s4655d8938t 5 9 hours hour NOUN s4655d8938t 5 10 post post NOUN s4655d8938t 5 11 fertilization fertilization NOUN s4655d8938t 5 12 ( ( PUNCT s4655d8938t 5 13 hpf hpf NOUN s4655d8938t 5 14 ) ) PUNCT s4655d8938t 5 15 and and CCONJ s4655d8938t 5 16 continued continue VERB s4655d8938t 5 17 to to PART s4655d8938t 5 18 increase increase VERB s4655d8938t 5 19 through through ADP s4655d8938t 5 20 5 5 NUM s4655d8938t 5 21 days day NOUN s4655d8938t 5 22 post post NOUN s4655d8938t 5 23 fertilization fertilization NOUN s4655d8938t 5 24 ( ( PUNCT s4655d8938t 5 25 dpf dpf NOUN s4655d8938t 5 26 ) ) PUNCT s4655d8938t 5 27 . . PUNCT s4655d8938t 6 1 in in ADP s4655d8938t 6 2 the the DET s4655d8938t 6 3 eye eye NOUN s4655d8938t 6 4 , , PUNCT s4655d8938t 6 5 expression expression NOUN s4655d8938t 6 6 of of ADP s4655d8938t 6 7 the the DET s4655d8938t 6 8 pitx3 pitx3 PROPN s4655d8938t 6 9 protein protein NOUN s4655d8938t 6 10 was be AUX s4655d8938t 6 11 restricted restrict VERB s4655d8938t 6 12 to to ADP s4655d8938t 6 13 the the DET s4655d8938t 6 14 lens lens NOUN s4655d8938t 6 15 epithelial epithelial ADJ s4655d8938t 6 16 cells cell NOUN s4655d8938t 6 17 and and CCONJ s4655d8938t 6 18 differentiating differentiate VERB s4655d8938t 6 19 lens lens NOUN s4655d8938t 6 20 fiber fiber NOUN s4655d8938t 6 21 cells cell NOUN s4655d8938t 6 22 . . PUNCT s4655d8938t 7 1 after after SCONJ s4655d8938t 7 2 injected inject VERB s4655d8938t 7 3 with with ADP s4655d8938t 7 4 antisense antisense NOUN s4655d8938t 7 5 morpholino morpholino NOUN s4655d8938t 7 6 to to ADP s4655d8938t 7 7 knockdown knockdown NOUN s4655d8938t 7 8 pitx3 pitx3 NOUN s4655d8938t 7 9 protein protein NOUN s4655d8938t 7 10 expression expression NOUN s4655d8938t 7 11 , , PUNCT s4655d8938t 7 12 the the DET s4655d8938t 7 13 morphant morphant NOUN s4655d8938t 7 14 embryos embryo NOUN s4655d8938t 7 15 exhibited exhibit VERB s4655d8938t 7 16 small small ADJ s4655d8938t 7 17 eyes eye NOUN s4655d8938t 7 18 with with ADP s4655d8938t 7 19 abnormal abnormal ADJ s4655d8938t 7 20 lens lens NOUN s4655d8938t 7 21 development development NOUN s4655d8938t 7 22 relative relative ADJ s4655d8938t 7 23 to to ADP s4655d8938t 7 24 the the DET s4655d8938t 7 25 controls control NOUN s4655d8938t 7 26 . . PUNCT s4655d8938t 8 1 the the DET s4655d8938t 8 2 morphant morphant PROPN s4655d8938t 8 3 retinas retina NOUN s4655d8938t 8 4 also also ADV s4655d8938t 8 5 contained contain VERB s4655d8938t 8 6 pyknotic pyknotic ADJ s4655d8938t 8 7 nuclei nucleus NOUN s4655d8938t 8 8 accompanied accompany VERB s4655d8938t 8 9 by by ADP s4655d8938t 8 10 a a DET s4655d8938t 8 11 reduction reduction NOUN s4655d8938t 8 12 in in ADP s4655d8938t 8 13 the the DET s4655d8938t 8 14 number number NOUN s4655d8938t 8 15 of of ADP s4655d8938t 8 16 cells cell NOUN s4655d8938t 8 17 in in ADP s4655d8938t 8 18 different different ADJ s4655d8938t 8 19 neuronal neuronal ADJ s4655d8938t 8 20 classes class NOUN s4655d8938t 8 21 . . PUNCT s4655d8938t 9 1 the the DET s4655d8938t 9 2 absence absence NOUN s4655d8938t 9 3 of of ADP s4655d8938t 9 4 detectable detectable ADJ s4655d8938t 9 5 pitx3 pitx3 NOUN s4655d8938t 9 6 protein protein NOUN s4655d8938t 9 7 expression expression NOUN s4655d8938t 9 8 in in ADP s4655d8938t 9 9 the the DET s4655d8938t 9 10 retina retina NOUN s4655d8938t 9 11 suggested suggest VERB s4655d8938t 9 12 that that SCONJ s4655d8938t 9 13 pitx3 pitx3 NOUN s4655d8938t 9 14 expression expression NOUN s4655d8938t 9 15 in in ADP s4655d8938t 9 16 the the DET s4655d8938t 9 17 lens lens NOUN s4655d8938t 9 18 induces induce VERB s4655d8938t 9 19 a a DET s4655d8938t 9 20 required require VERB s4655d8938t 9 21 effect effect NOUN s4655d8938t 9 22 on on ADP s4655d8938t 9 23 retinal retinal ADJ s4655d8938t 9 24 development development NOUN s4655d8938t 9 25 . . PUNCT s4655d8938t 10 1 the the DET s4655d8938t 10 2 intronless intronless PROPN s4655d8938t 10 3 organization organization NOUN s4655d8938t 10 4 of of ADP s4655d8938t 10 5 the the DET s4655d8938t 10 6 zebrafish zebrafish ADJ s4655d8938t 10 7 foxe3 foxe3 NOUN s4655d8938t 10 8 gene gene NOUN s4655d8938t 10 9 is be AUX s4655d8938t 10 10 conserved conserve VERB s4655d8938t 10 11 among among ADP s4655d8938t 10 12 its its PRON s4655d8938t 10 13 mammalian mammalian ADJ s4655d8938t 10 14 homologs homolog NOUN s4655d8938t 10 15 . . PUNCT s4655d8938t 11 1 it it PRON s4655d8938t 11 2 encodes encode VERB s4655d8938t 11 3 a a DET s4655d8938t 11 4 protein protein NOUN s4655d8938t 11 5 of of ADP s4655d8938t 11 6 422 422 NUM s4655d8938t 11 7 amino amino NOUN s4655d8938t 11 8 acids acid NOUN s4655d8938t 11 9 . . PUNCT s4655d8938t 12 1 the the DET s4655d8938t 12 2 foxe3 foxe3 PROPN s4655d8938t 12 3 protein protein NOUN s4655d8938t 12 4 , , PUNCT s4655d8938t 12 5 which which PRON s4655d8938t 12 6 is be AUX s4655d8938t 12 7 first first ADV s4655d8938t 12 8 detected detect VERB s4655d8938t 12 9 on on ADP s4655d8938t 12 10 immunoblots immunoblot NOUN s4655d8938t 12 11 at at ADP s4655d8938t 12 12 24 24 NUM s4655d8938t 12 13 hpf hpf NOUN s4655d8938t 12 14 , , PUNCT s4655d8938t 12 15 persists persist VERB s4655d8938t 12 16 throughout throughout ADP s4655d8938t 12 17 development development NOUN s4655d8938t 12 18 , , PUNCT s4655d8938t 12 19 with with ADP s4655d8938t 12 20 the the DET s4655d8938t 12 21 greatest great ADJ s4655d8938t 12 22 expression expression NOUN s4655d8938t 12 23 levels level NOUN s4655d8938t 12 24 at at ADP s4655d8938t 12 25 4 4 NUM s4655d8938t 12 26 and and CCONJ s4655d8938t 12 27 5 5 NUM s4655d8938t 12 28 dpf dpf NOUN s4655d8938t 12 29 . . PUNCT s4655d8938t 13 1 within within ADP s4655d8938t 13 2 the the DET s4655d8938t 13 3 lens lens NOUN s4655d8938t 13 4 , , PUNCT s4655d8938t 13 5 the the DET s4655d8938t 13 6 foxe3 foxe3 X s4655d8938t 13 7 protein protein NOUN s4655d8938t 13 8 was be AUX s4655d8938t 13 9 restricted restrict VERB s4655d8938t 13 10 to to ADP s4655d8938t 13 11 the the DET s4655d8938t 13 12 lens lens NOUN s4655d8938t 13 13 epithelial epithelial ADJ s4655d8938t 13 14 cells cell NOUN s4655d8938t 13 15 and and CCONJ s4655d8938t 13 16 differentiating differentiate VERB s4655d8938t 13 17 fiber fiber NOUN s4655d8938t 13 18 cells cell NOUN s4655d8938t 13 19 , , PUNCT s4655d8938t 13 20 in in ADP s4655d8938t 13 21 the the DET s4655d8938t 13 22 same same ADJ s4655d8938t 13 23 manner manner NOUN s4655d8938t 13 24 as as ADP s4655d8938t 13 25 its its PRON s4655d8938t 13 26 mouse mouse NOUN s4655d8938t 13 27 homolog homolog NOUN s4655d8938t 13 28 and and CCONJ s4655d8938t 13 29 pitx3 pitx3 PROPN s4655d8938t 13 30 . . PUNCT s4655d8938t 14 1 anti anti ADJ s4655d8938t 14 2 - - ADJ s4655d8938t 14 3 foxe3 foxe3 ADJ s4655d8938t 14 4 morphants morphant NOUN s4655d8938t 14 5 exhibited exhibit VERB s4655d8938t 14 6 a a DET s4655d8938t 14 7 small small ADJ s4655d8938t 14 8 lens lens NOUN s4655d8938t 14 9 with with ADP s4655d8938t 14 10 increased increase VERB s4655d8938t 14 11 number number NOUN s4655d8938t 14 12 of of ADP s4655d8938t 14 13 nucleated nucleated ADJ s4655d8938t 14 14 cells cell NOUN s4655d8938t 14 15 , , PUNCT s4655d8938t 14 16 disordered disordered ADJ s4655d8938t 14 17 arrangement arrangement NOUN s4655d8938t 14 18 of of ADP s4655d8938t 14 19 fiber fiber NOUN s4655d8938t 14 20 cells cell NOUN s4655d8938t 14 21 and and CCONJ s4655d8938t 14 22 alteration alteration NOUN s4655d8938t 14 23 of of ADP s4655d8938t 14 24 lens lens NOUN s4655d8938t 14 25 cell cell NOUN s4655d8938t 14 26 fates fate NOUN s4655d8938t 14 27 . . PUNCT s4655d8938t 15 1 there there PRON s4655d8938t 15 2 was be VERB s4655d8938t 15 3 no no DET s4655d8938t 15 4 detectable detectable ADJ s4655d8938t 15 5 change change NOUN s4655d8938t 15 6 in in ADP s4655d8938t 15 7 the the DET s4655d8938t 15 8 morphant morphant NOUN s4655d8938t 15 9 retina retina NOUN s4655d8938t 15 10 . . PUNCT s4655d8938t 16 1 neither neither CCONJ s4655d8938t 16 2 pitx3 pitx3 PROPN s4655d8938t 16 3 nor nor CCONJ s4655d8938t 16 4 & & CCONJ s4655d8938t 16 5 gamma;a gamma;a PROPN s4655d8938t 16 6 - - PUNCT s4655d8938t 16 7 crystallin crystallin NOUN s4655d8938t 16 8 expression expression NOUN s4655d8938t 16 9 levels level NOUN s4655d8938t 16 10 were be AUX s4655d8938t 16 11 affected affect VERB s4655d8938t 16 12 in in ADP s4655d8938t 16 13 the the DET s4655d8938t 16 14 anti anti ADJ s4655d8938t 16 15 - - ADJ s4655d8938t 16 16 foxe3 foxe3 ADJ s4655d8938t 16 17 morphants morphant NOUN s4655d8938t 16 18 . . PUNCT s4655d8938t 17 1 in in ADP s4655d8938t 17 2 contrast contrast NOUN s4655d8938t 17 3 , , PUNCT s4655d8938t 17 4 the the DET s4655d8938t 17 5 anti anti ADJ s4655d8938t 17 6 - - ADJ s4655d8938t 17 7 pitx3 pitx3 ADJ s4655d8938t 17 8 morphants morphant NOUN s4655d8938t 17 9 had have VERB s4655d8938t 17 10 no no DET s4655d8938t 17 11 detectable detectable ADJ s4655d8938t 17 12 foxe3 foxe3 NOUN s4655d8938t 17 13 proteins protein NOUN s4655d8938t 17 14 on on ADP s4655d8938t 17 15 immunoblots immunoblot NOUN s4655d8938t 17 16 and and CCONJ s4655d8938t 17 17 reduced reduce VERB s4655d8938t 17 18 & & CCONJ s4655d8938t 17 19 gamma;a gamma;a PROPN s4655d8938t 17 20 - - PUNCT s4655d8938t 17 21 crystallin crystallin NOUN s4655d8938t 17 22 expression expression NOUN s4655d8938t 17 23 levels level NOUN s4655d8938t 17 24 on on ADP s4655d8938t 17 25 eye eye NOUN s4655d8938t 17 26 tissue tissue NOUN s4655d8938t 17 27 sections section NOUN s4655d8938t 17 28 . . PUNCT s4655d8938t 18 1 the the DET s4655d8938t 18 2 expression expression NOUN s4655d8938t 18 3 and and CCONJ s4655d8938t 18 4 functional functional ADJ s4655d8938t 18 5 analysis analysis NOUN s4655d8938t 18 6 suggests suggest VERB s4655d8938t 18 7 the the DET s4655d8938t 18 8 expression expression NOUN s4655d8938t 18 9 of of ADP s4655d8938t 18 10 both both CCONJ s4655d8938t 18 11 the the DET s4655d8938t 18 12 foxe3 foxe3 PROPN s4655d8938t 18 13 and and CCONJ s4655d8938t 18 14 & & CCONJ s4655d8938t 18 15 gamma;a gamma;a PROPN s4655d8938t 18 16 - - PUNCT s4655d8938t 18 17 crystallin crystallin NOUN s4655d8938t 18 18 genes gene NOUN s4655d8938t 18 19 requires require VERB s4655d8938t 18 20 the the DET s4655d8938t 18 21 normal normal ADJ s4655d8938t 18 22 expression expression NOUN s4655d8938t 18 23 of of ADP s4655d8938t 18 24 pitx3 pitx3 PROPN s4655d8938t 18 25 . . PUNCT