id	sid	tid	token	lemma	pos
s1784j05v46	1	1	one	one	NUM
s1784j05v46	1	2	of	of	ADP
s1784j05v46	1	3	the	the	DET
s1784j05v46	1	4	most	most	ADV
s1784j05v46	1	5	intriguing	intriguing	ADJ
s1784j05v46	1	6	aspects	aspect	NOUN
s1784j05v46	1	7	of	of	ADP
s1784j05v46	1	8	bone	bone	NOUN
s1784j05v46	1	9	is	be	AUX
s1784j05v46	1	10	its	its	PRON
s1784j05v46	1	11	ability	ability	NOUN
s1784j05v46	1	12	to	to	PART
s1784j05v46	1	13	grow	grow	VERB
s1784j05v46	1	14	,	,	PUNCT
s1784j05v46	1	15	repair	repair	NOUN
s1784j05v46	1	16	damage	damage	NOUN
s1784j05v46	1	17	,	,	PUNCT
s1784j05v46	1	18	adapt	adapt	VERB
s1784j05v46	1	19	to	to	ADP
s1784j05v46	1	20	mechanical	mechanical	ADJ
s1784j05v46	1	21	loads	load	NOUN
s1784j05v46	1	22	,	,	PUNCT
s1784j05v46	1	23	and	and	CCONJ
s1784j05v46	1	24	maintain	maintain	VERB
s1784j05v46	1	25	mineral	mineral	NOUN
s1784j05v46	1	26	homeostasis	homeostasis	NOUN
s1784j05v46	1	27	.	.	PUNCT
s1784j05v46	2	1	it	it	PRON
s1784j05v46	2	2	is	be	AUX
s1784j05v46	2	3	generally	generally	ADV
s1784j05v46	2	4	accepted	accept	VERB
s1784j05v46	2	5	that	that	SCONJ
s1784j05v46	2	6	bone	bone	NOUN
s1784j05v46	2	7	adaptation	adaptation	NOUN
s1784j05v46	2	8	occurs	occur	VERB
s1784j05v46	2	9	in	in	ADP
s1784j05v46	2	10	response	response	NOUN
s1784j05v46	2	11	to	to	ADP
s1784j05v46	2	12	the	the	DET
s1784j05v46	2	13	mechanical	mechanical	ADJ
s1784j05v46	2	14	demands	demand	NOUN
s1784j05v46	2	15	of	of	ADP
s1784j05v46	2	16	our	our	PRON
s1784j05v46	2	17	daily	daily	ADJ
s1784j05v46	2	18	activities	activity	NOUN
s1784j05v46	2	19	;	;	PUNCT
s1784j05v46	2	20	moreover	moreover	ADV
s1784j05v46	2	21	,	,	PUNCT
s1784j05v46	2	22	strain	strain	NOUN
s1784j05v46	2	23	and	and	CCONJ
s1784j05v46	2	24	microdamage	microdamage	NOUN
s1784j05v46	2	25	have	have	AUX
s1784j05v46	2	26	been	be	AUX
s1784j05v46	2	27	implicated	implicate	VERB
s1784j05v46	2	28	as	as	ADP
s1784j05v46	2	29	potential	potential	ADJ
s1784j05v46	2	30	stimuli	stimulus	NOUN
s1784j05v46	2	31	that	that	PRON
s1784j05v46	2	32	regulate	regulate	VERB
s1784j05v46	2	33	this	this	DET
s1784j05v46	2	34	sophisticated	sophisticated	ADJ
s1784j05v46	2	35	process	process	NOUN
s1784j05v46	2	36	.	.	PUNCT
s1784j05v46	3	1	while	while	SCONJ
s1784j05v46	3	2	researchers	researcher	NOUN
s1784j05v46	3	3	have	have	AUX
s1784j05v46	3	4	made	make	VERB
s1784j05v46	3	5	significant	significant	ADJ
s1784j05v46	3	6	advances	advance	NOUN
s1784j05v46	3	7	in	in	ADP
s1784j05v46	3	8	our	our	PRON
s1784j05v46	3	9	understanding	understanding	NOUN
s1784j05v46	3	10	of	of	ADP
s1784j05v46	3	11	the	the	DET
s1784j05v46	3	12	bone	bone	NOUN
s1784j05v46	3	13	adaptation	adaptation	NOUN
s1784j05v46	3	14	process	process	NOUN
s1784j05v46	3	15	,	,	PUNCT
s1784j05v46	3	16	there	there	PRON
s1784j05v46	3	17	are	be	VERB
s1784j05v46	3	18	many	many	ADJ
s1784j05v46	3	19	aspects	aspect	NOUN
s1784j05v46	3	20	that	that	PRON
s1784j05v46	3	21	remain	remain	VERB
s1784j05v46	3	22	unknown	unknown	ADJ
s1784j05v46	3	23	.	.	PUNCT
s1784j05v46	4	1	for	for	ADP
s1784j05v46	4	2	instance	instance	NOUN
s1784j05v46	4	3	,	,	PUNCT
s1784j05v46	4	4	it	it	PRON
s1784j05v46	4	5	is	be	AUX
s1784j05v46	4	6	not	not	PART
s1784j05v46	4	7	fully	fully	ADV
s1784j05v46	4	8	understood	understand	VERB
s1784j05v46	4	9	how	how	SCONJ
s1784j05v46	4	10	the	the	DET
s1784j05v46	4	11	mechanical	mechanical	ADJ
s1784j05v46	4	12	stimulation	stimulation	NOUN
s1784j05v46	4	13	experienced	experience	VERB
s1784j05v46	4	14	by	by	ADP
s1784j05v46	4	15	bones	bone	NOUN
s1784j05v46	4	16	influences	influence	VERB
s1784j05v46	4	17	the	the	DET
s1784j05v46	4	18	biochemical	biochemical	ADJ
s1784j05v46	4	19	signaling	signaling	NOUN
s1784j05v46	4	20	that	that	PRON
s1784j05v46	4	21	drives	drive	VERB
s1784j05v46	4	22	the	the	DET
s1784j05v46	4	23	cellular	cellular	ADJ
s1784j05v46	4	24	activity	activity	NOUN
s1784j05v46	4	25	of	of	ADP
s1784j05v46	4	26	remodeling	remodeling	NOUN
s1784j05v46	4	27	.	.	PUNCT
s1784j05v46	5	1	due	due	ADP
s1784j05v46	5	2	to	to	ADP
s1784j05v46	5	3	the	the	DET
s1784j05v46	5	4	fact	fact	NOUN
s1784j05v46	5	5	that	that	SCONJ
s1784j05v46	5	6	evidence	evidence	NOUN
s1784j05v46	5	7	for	for	ADP
s1784j05v46	5	8	bone	bone	NOUN
s1784j05v46	5	9	metabolic	metabolic	NOUN
s1784j05v46	5	10	diseases	disease	NOUN
s1784j05v46	5	11	points	point	VERB
s1784j05v46	5	12	toward	toward	ADP
s1784j05v46	5	13	the	the	DET
s1784j05v46	5	14	disruption	disruption	NOUN
s1784j05v46	5	15	of	of	ADP
s1784j05v46	5	16	the	the	DET
s1784j05v46	5	17	cellular	cellular	ADJ
s1784j05v46	5	18	mechanisms	mechanism	NOUN
s1784j05v46	5	19	of	of	ADP
s1784j05v46	5	20	remodeling	remodeling	NOUN
s1784j05v46	5	21	,	,	PUNCT
s1784j05v46	5	22	such	such	DET
s1784j05v46	5	23	a	a	DET
s1784j05v46	5	24	relationship	relationship	NOUN
s1784j05v46	5	25	is	be	AUX
s1784j05v46	5	26	crucial	crucial	ADJ
s1784j05v46	5	27	to	to	ADP
s1784j05v46	5	28	understanding	understand	VERB
s1784j05v46	5	29	the	the	DET
s1784j05v46	5	30	key	key	ADJ
s1784j05v46	5	31	factors	factor	NOUN
s1784j05v46	5	32	that	that	PRON
s1784j05v46	5	33	result	result	VERB
s1784j05v46	5	34	in	in	ADP
s1784j05v46	5	35	pathological	pathological	ADJ
s1784j05v46	5	36	remodeling	remodeling	NOUN
s1784j05v46	5	37	activity	activity	NOUN
s1784j05v46	5	38	.	.	PUNCT
s1784j05v46	6	1	over	over	ADP
s1784j05v46	6	2	the	the	DET
s1784j05v46	6	3	past	past	ADJ
s1784j05v46	6	4	several	several	ADJ
s1784j05v46	6	5	decades	decade	NOUN
s1784j05v46	6	6	,	,	PUNCT
s1784j05v46	6	7	various	various	ADJ
s1784j05v46	6	8	theoretical	theoretical	ADJ
s1784j05v46	6	9	and	and	CCONJ
s1784j05v46	6	10	computational	computational	ADJ
s1784j05v46	6	11	models	model	NOUN
s1784j05v46	6	12	have	have	AUX
s1784j05v46	6	13	been	be	AUX
s1784j05v46	6	14	developed	develop	VERB
s1784j05v46	6	15	to	to	PART
s1784j05v46	6	16	study	study	VERB
s1784j05v46	6	17	the	the	DET
s1784j05v46	6	18	bone	bone	NOUN
s1784j05v46	6	19	adaptation	adaptation	NOUN
s1784j05v46	6	20	process	process	NOUN
s1784j05v46	6	21	.	.	PUNCT
s1784j05v46	7	1	these	these	DET
s1784j05v46	7	2	computational	computational	ADJ
s1784j05v46	7	3	models	model	NOUN
s1784j05v46	7	4	have	have	AUX
s1784j05v46	7	5	primarily	primarily	ADV
s1784j05v46	7	6	focused	focus	VERB
s1784j05v46	7	7	on	on	ADP
s1784j05v46	7	8	predicting	predict	VERB
s1784j05v46	7	9	net	net	ADJ
s1784j05v46	7	10	changes	change	NOUN
s1784j05v46	7	11	in	in	ADP
s1784j05v46	7	12	organ	organ	NOUN
s1784j05v46	7	13	and	and	CCONJ
s1784j05v46	7	14	tissue	tissue	NOUN
s1784j05v46	7	15	level	level	NOUN
s1784j05v46	7	16	bone	bone	NOUN
s1784j05v46	7	17	architecture	architecture	NOUN
s1784j05v46	7	18	.	.	PUNCT
s1784j05v46	8	1	while	while	SCONJ
s1784j05v46	8	2	these	these	DET
s1784j05v46	8	3	simulations	simulation	NOUN
s1784j05v46	8	4	are	be	AUX
s1784j05v46	8	5	able	able	ADJ
s1784j05v46	8	6	to	to	PART
s1784j05v46	8	7	capture	capture	VERB
s1784j05v46	8	8	phenomena	phenomenon	NOUN
s1784j05v46	8	9	such	such	ADJ
s1784j05v46	8	10	as	as	ADP
s1784j05v46	8	11	net	net	ADJ
s1784j05v46	8	12	increases	increase	NOUN
s1784j05v46	8	13	or	or	CCONJ
s1784j05v46	8	14	decreases	decrease	NOUN
s1784j05v46	8	15	in	in	ADP
s1784j05v46	8	16	bone	bone	NOUN
s1784j05v46	8	17	volume	volume	NOUN
s1784j05v46	8	18	or	or	CCONJ
s1784j05v46	8	19	reorientation	reorientation	NOUN
s1784j05v46	8	20	of	of	ADP
s1784j05v46	8	21	tissue	tissue	NOUN
s1784j05v46	8	22	level	level	NOUN
s1784j05v46	8	23	structures	structure	NOUN
s1784j05v46	8	24	,	,	PUNCT
s1784j05v46	8	25	they	they	PRON
s1784j05v46	8	26	do	do	AUX
s1784j05v46	8	27	not	not	PART
s1784j05v46	8	28	capture	capture	VERB
s1784j05v46	8	29	cellular	cellular	ADJ
s1784j05v46	8	30	level	level	NOUN
s1784j05v46	8	31	details	detail	NOUN
s1784j05v46	8	32	.	.	PUNCT
s1784j05v46	9	1	in	in	ADP
s1784j05v46	9	2	an	an	DET
s1784j05v46	9	3	attempt	attempt	NOUN
s1784j05v46	9	4	to	to	PART
s1784j05v46	9	5	ameliorate	ameliorate	VERB
s1784j05v46	9	6	this	this	DET
s1784j05v46	9	7	deficiency	deficiency	NOUN
s1784j05v46	9	8	of	of	ADP
s1784j05v46	9	9	previous	previous	ADJ
s1784j05v46	9	10	models	model	NOUN
s1784j05v46	9	11	,	,	PUNCT
s1784j05v46	9	12	more	more	ADJ
s1784j05v46	9	13	recent	recent	ADJ
s1784j05v46	9	14	studies	study	NOUN
s1784j05v46	9	15	have	have	AUX
s1784j05v46	9	16	focused	focus	VERB
s1784j05v46	9	17	on	on	ADP
s1784j05v46	9	18	simulating	simulate	VERB
s1784j05v46	9	19	the	the	DET
s1784j05v46	9	20	remodeling	remodeling	NOUN
s1784j05v46	9	21	response	response	NOUN
s1784j05v46	9	22	at	at	ADP
s1784j05v46	9	23	a	a	DET
s1784j05v46	9	24	single	single	ADJ
s1784j05v46	9	25	site	site	NOUN
s1784j05v46	9	26	in	in	ADP
s1784j05v46	9	27	bone	bone	NOUN
s1784j05v46	9	28	.	.	PUNCT
s1784j05v46	10	1	however	however	ADV
s1784j05v46	10	2	,	,	PUNCT
s1784j05v46	10	3	few	few	ADJ
s1784j05v46	10	4	models	model	NOUN
s1784j05v46	10	5	attempt	attempt	VERB
s1784j05v46	10	6	to	to	PART
s1784j05v46	10	7	combine	combine	VERB
s1784j05v46	10	8	models	model	NOUN
s1784j05v46	10	9	of	of	ADP
s1784j05v46	10	10	cellular	cellular	ADJ
s1784j05v46	10	11	activity	activity	NOUN
s1784j05v46	10	12	with	with	ADP
s1784j05v46	10	13	the	the	DET
s1784j05v46	10	14	classical	classical	ADJ
s1784j05v46	10	15	phenomenological	phenomenological	ADJ
s1784j05v46	10	16	remodeling	remodeling	NOUN
s1784j05v46	10	17	paradigms	paradigm	NOUN
s1784j05v46	10	18	.	.	PUNCT
s1784j05v46	11	1	the	the	DET
s1784j05v46	11	2	primary	primary	ADJ
s1784j05v46	11	3	focus	focus	NOUN
s1784j05v46	11	4	of	of	ADP
s1784j05v46	11	5	this	this	DET
s1784j05v46	11	6	dissertation	dissertation	NOUN
s1784j05v46	11	7	is	be	AUX
s1784j05v46	11	8	to	to	PART
s1784j05v46	11	9	present	present	VERB
s1784j05v46	11	10	a	a	DET
s1784j05v46	11	11	new	new	ADJ
s1784j05v46	11	12	computational	computational	ADJ
s1784j05v46	11	13	framework	framework	NOUN
s1784j05v46	11	14	that	that	PRON
s1784j05v46	11	15	mechanistically	mechanistically	ADV
s1784j05v46	11	16	models	model	VERB
s1784j05v46	11	17	the	the	DET
s1784j05v46	11	18	cellular	cellular	ADJ
s1784j05v46	11	19	behavior	behavior	NOUN
s1784j05v46	11	20	involved	involve	VERB
s1784j05v46	11	21	in	in	ADP
s1784j05v46	11	22	the	the	DET
s1784j05v46	11	23	bone	bone	NOUN
s1784j05v46	11	24	remodeling	remodeling	NOUN
s1784j05v46	11	25	process	process	NOUN
s1784j05v46	11	26	.	.	PUNCT
s1784j05v46	12	1	this	this	DET
s1784j05v46	12	2	framework	framework	NOUN
s1784j05v46	12	3	uniquely	uniquely	ADV
s1784j05v46	12	4	combines	combine	VERB
s1784j05v46	12	5	established	establish	VERB
s1784j05v46	12	6	phenomenological	phenomenological	ADJ
s1784j05v46	12	7	remodeling	remodeling	NOUN
s1784j05v46	12	8	paradigms	paradigm	NOUN
s1784j05v46	12	9	with	with	ADP
s1784j05v46	12	10	cellular	cellular	ADJ
s1784j05v46	12	11	mechanisms	mechanism	NOUN
s1784j05v46	12	12	to	to	PART
s1784j05v46	12	13	predict	predict	VERB
s1784j05v46	12	14	remodeling	remodeling	NOUN
s1784j05v46	12	15	activity	activity	NOUN
s1784j05v46	12	16	for	for	ADP
s1784j05v46	12	17	a	a	DET
s1784j05v46	12	18	damaged	damage	VERB
s1784j05v46	12	19	site	site	NOUN
s1784j05v46	12	20	in	in	ADP
s1784j05v46	12	21	bone	bone	NOUN
s1784j05v46	12	22	.	.	PUNCT
s1784j05v46	13	1	biological	biological	ADJ
s1784j05v46	13	2	rules	rule	NOUN
s1784j05v46	13	3	were	be	AUX
s1784j05v46	13	4	implemented	implement	VERB
s1784j05v46	13	5	to	to	PART
s1784j05v46	13	6	control	control	VERB
s1784j05v46	13	7	the	the	DET
s1784j05v46	13	8	recruitment	recruitment	NOUN
s1784j05v46	13	9	,	,	PUNCT
s1784j05v46	13	10	differentiation	differentiation	NOUN
s1784j05v46	13	11	,	,	PUNCT
s1784j05v46	13	12	and	and	CCONJ
s1784j05v46	13	13	activation	activation	NOUN
s1784j05v46	13	14	of	of	ADP
s1784j05v46	13	15	osteoclasts	osteoclast	NOUN
s1784j05v46	13	16	and	and	CCONJ
s1784j05v46	13	17	osteoblasts	osteoblast	NOUN
s1784j05v46	13	18	,	,	PUNCT
s1784j05v46	13	19	based	base	VERB
s1784j05v46	13	20	on	on	ADP
s1784j05v46	13	21	observations	observation	NOUN
s1784j05v46	13	22	from	from	ADP
s1784j05v46	13	23	histological	histological	ADJ
s1784j05v46	13	24	studies	study	NOUN
s1784j05v46	13	25	.	.	PUNCT
s1784j05v46	14	1	the	the	DET
s1784j05v46	14	2	results	result	NOUN
s1784j05v46	14	3	of	of	ADP
s1784j05v46	14	4	this	this	DET
s1784j05v46	14	5	work	work	NOUN
s1784j05v46	14	6	are	be	AUX
s1784j05v46	14	7	the	the	DET
s1784j05v46	14	8	first	first	ADJ
s1784j05v46	14	9	of	of	ADP
s1784j05v46	14	10	their	their	PRON
s1784j05v46	14	11	kind	kind	NOUN
s1784j05v46	14	12	to	to	PART
s1784j05v46	14	13	demonstrate	demonstrate	VERB
s1784j05v46	14	14	spatially	spatially	ADV
s1784j05v46	14	15	and	and	CCONJ
s1784j05v46	14	16	temporally	temporally	ADV
s1784j05v46	14	17	accurate	accurate	ADJ
s1784j05v46	14	18	remodeling	remodeling	NOUN
s1784j05v46	14	19	behavior	behavior	NOUN
s1784j05v46	14	20	at	at	ADP
s1784j05v46	14	21	the	the	DET
s1784j05v46	14	22	cellular	cellular	ADJ
s1784j05v46	14	23	level	level	NOUN
s1784j05v46	14	24	.	.	PUNCT
s1784j05v46	15	1	furthermore	furthermore	ADV
s1784j05v46	15	2	,	,	PUNCT
s1784j05v46	15	3	these	these	DET
s1784j05v46	15	4	results	result	NOUN
s1784j05v46	15	5	provide	provide	VERB
s1784j05v46	15	6	unique	unique	ADJ
s1784j05v46	15	7	insights	insight	NOUN
s1784j05v46	15	8	regarding	regard	VERB
s1784j05v46	15	9	key	key	ADJ
s1784j05v46	15	10	parameters	parameter	NOUN
s1784j05v46	15	11	that	that	PRON
s1784j05v46	15	12	influence	influence	VERB
s1784j05v46	15	13	cellular	cellular	ADJ
s1784j05v46	15	14	level	level	NOUN
s1784j05v46	15	15	remodeling	remodeling	NOUN
s1784j05v46	15	16	activity	activity	NOUN
s1784j05v46	15	17	.	.	PUNCT