id sid tid token lemma pos rb68x92423x 1 1 in in ADP rb68x92423x 1 2 the the DET rb68x92423x 1 3 modern modern ADJ rb68x92423x 1 4 world world NOUN rb68x92423x 1 5 , , PUNCT rb68x92423x 1 6 myocardial myocardial ADJ rb68x92423x 1 7 infarction infarction NOUN rb68x92423x 1 8 is be AUX rb68x92423x 1 9 one one NUM rb68x92423x 1 10 of of ADP rb68x92423x 1 11 the the DET rb68x92423x 1 12 most most ADV rb68x92423x 1 13 common common ADJ rb68x92423x 1 14 cardiovascular cardiovascular ADJ rb68x92423x 1 15 diseases disease NOUN rb68x92423x 1 16 , , PUNCT rb68x92423x 1 17 which which PRON rb68x92423x 1 18 are be AUX rb68x92423x 1 19 responsible responsible ADJ rb68x92423x 1 20 for for ADP rb68x92423x 1 21 around around ADP rb68x92423x 1 22 18 18 NUM rb68x92423x 1 23 million million NUM rb68x92423x 1 24 deaths death NOUN rb68x92423x 1 25 every every DET rb68x92423x 1 26 year year NOUN rb68x92423x 1 27 or or CCONJ rb68x92423x 1 28 almost almost ADV rb68x92423x 1 29 32 32 NUM rb68x92423x 1 30 % % NOUN rb68x92423x 1 31 of of ADP rb68x92423x 1 32 all all DET rb68x92423x 1 33 deaths death NOUN rb68x92423x 1 34 . . PUNCT rb68x92423x 2 1 although although SCONJ rb68x92423x 2 2 there there PRON rb68x92423x 2 3 has have AUX rb68x92423x 2 4 been be AUX rb68x92423x 2 5 some some DET rb68x92423x 2 6 progress progress NOUN rb68x92423x 2 7 in in ADP rb68x92423x 2 8 regenerative regenerative ADJ rb68x92423x 2 9 therapies therapy NOUN rb68x92423x 2 10 available available ADJ rb68x92423x 2 11 for for ADP rb68x92423x 2 12 myocardial myocardial ADJ rb68x92423x 2 13 infarction infarction NOUN rb68x92423x 2 14 treatment treatment NOUN rb68x92423x 2 15 , , PUNCT rb68x92423x 2 16 translating translate VERB rb68x92423x 2 17 pre pre ADJ rb68x92423x 2 18 - - ADJ rb68x92423x 2 19 clinical clinical ADJ rb68x92423x 2 20 findings finding NOUN rb68x92423x 2 21 to to ADP rb68x92423x 2 22 the the DET rb68x92423x 2 23 clinic clinic NOUN rb68x92423x 2 24 remains remain VERB rb68x92423x 2 25 a a DET rb68x92423x 2 26 major major ADJ rb68x92423x 2 27 challenge challenge NOUN rb68x92423x 2 28 . . PUNCT rb68x92423x 3 1 one one NUM rb68x92423x 3 2 reason reason NOUN rb68x92423x 3 3 for for ADP rb68x92423x 3 4 this this PRON rb68x92423x 3 5 is be AUX rb68x92423x 3 6 the the DET rb68x92423x 3 7 lack lack NOUN rb68x92423x 3 8 of of ADP rb68x92423x 3 9 reliable reliable ADJ rb68x92423x 3 10 and and CCONJ rb68x92423x 3 11 human human ADJ rb68x92423x 3 12 representative representative NOUN rb68x92423x 3 13 healthy healthy ADJ rb68x92423x 3 14 and and CCONJ rb68x92423x 3 15 fibrotic fibrotic ADJ rb68x92423x 3 16 cardiac cardiac ADJ rb68x92423x 3 17 tissue tissue NOUN rb68x92423x 3 18 models model NOUN rb68x92423x 3 19 that that PRON rb68x92423x 3 20 can can AUX rb68x92423x 3 21 be be AUX rb68x92423x 3 22 used use VERB rb68x92423x 3 23 to to PART rb68x92423x 3 24 understand understand VERB rb68x92423x 3 25 the the DET rb68x92423x 3 26 fundamentals fundamental NOUN rb68x92423x 3 27 of of ADP rb68x92423x 3 28 ischemic ischemic ADJ rb68x92423x 3 29 / / SYM rb68x92423x 3 30 reperfusion reperfusion NOUN rb68x92423x 3 31 injury injury NOUN rb68x92423x 3 32 caused cause VERB rb68x92423x 3 33 by by ADP rb68x92423x 3 34 myocardial myocardial ADJ rb68x92423x 3 35 infarction infarction NOUN rb68x92423x 3 36 and and CCONJ rb68x92423x 3 37 to to PART rb68x92423x 3 38 test test VERB rb68x92423x 3 39 new new ADJ rb68x92423x 3 40 drugs drug NOUN rb68x92423x 3 41 and and CCONJ rb68x92423x 3 42 therapeutic therapeutic ADJ rb68x92423x 3 43 strategies.with strategies.with ADP rb68x92423x 3 44 the the DET rb68x92423x 3 45 inability inability NOUN rb68x92423x 3 46 to to PART rb68x92423x 3 47 use use VERB rb68x92423x 3 48 human human ADJ rb68x92423x 3 49 hearts heart NOUN rb68x92423x 3 50 at at ADP rb68x92423x 3 51 a a DET rb68x92423x 3 52 rate rate NOUN rb68x92423x 3 53 required require VERB rb68x92423x 3 54 for for ADP rb68x92423x 3 55 experimental experimental ADJ rb68x92423x 3 56 research research NOUN rb68x92423x 3 57 , , PUNCT rb68x92423x 3 58 the the DET rb68x92423x 3 59 majority majority NOUN rb68x92423x 3 60 of of ADP rb68x92423x 3 61 our our PRON rb68x92423x 3 62 current current ADJ rb68x92423x 3 63 knowledge knowledge NOUN rb68x92423x 3 64 on on ADP rb68x92423x 3 65 how how SCONJ rb68x92423x 3 66 the the DET rb68x92423x 3 67 constituents constituent NOUN rb68x92423x 3 68 of of ADP rb68x92423x 3 69 the the DET rb68x92423x 3 70 cardiovascular cardiovascular ADJ rb68x92423x 3 71 system system NOUN rb68x92423x 3 72 ( ( PUNCT rb68x92423x 3 73 cvs cvs PROPN rb68x92423x 3 74 ) ) PUNCT rb68x92423x 3 75 function function NOUN rb68x92423x 3 76 has have AUX rb68x92423x 3 77 been be AUX rb68x92423x 3 78 obtained obtain VERB rb68x92423x 3 79 through through ADP rb68x92423x 3 80 the the DET rb68x92423x 3 81 use use NOUN rb68x92423x 3 82 of of ADP rb68x92423x 3 83 animal animal NOUN rb68x92423x 3 84 models model NOUN rb68x92423x 3 85 . . PUNCT rb68x92423x 4 1 during during ADP rb68x92423x 4 2 the the DET rb68x92423x 4 3 past past ADJ rb68x92423x 4 4 couple couple NOUN rb68x92423x 4 5 decades decade NOUN rb68x92423x 4 6 , , PUNCT rb68x92423x 4 7 emerging emerge VERB rb68x92423x 4 8 tissue tissue NOUN rb68x92423x 4 9 engineering engineering NOUN rb68x92423x 4 10 methods method NOUN rb68x92423x 4 11 allowed allow VERB rb68x92423x 4 12 researchers researcher NOUN rb68x92423x 4 13 to to PART rb68x92423x 4 14 create create VERB rb68x92423x 4 15 biomimetic biomimetic ADJ rb68x92423x 4 16 tissue tissue NOUN rb68x92423x 4 17 models model NOUN rb68x92423x 4 18 in in ADP rb68x92423x 4 19 vitro vitro X rb68x92423x 4 20 , , PUNCT rb68x92423x 4 21 eliminating eliminate VERB rb68x92423x 4 22 the the DET rb68x92423x 4 23 need need NOUN rb68x92423x 4 24 for for ADP rb68x92423x 4 25 the the DET rb68x92423x 4 26 interspecies interspecie NOUN rb68x92423x 4 27 translation translation NOUN rb68x92423x 4 28 of of ADP rb68x92423x 4 29 the the DET rb68x92423x 4 30 results result NOUN rb68x92423x 4 31 , , PUNCT rb68x92423x 4 32 as as ADV rb68x92423x 4 33 well well ADV rb68x92423x 4 34 as as ADP rb68x92423x 4 35 concerns concern NOUN rb68x92423x 4 36 for for ADP rb68x92423x 4 37 the the DET rb68x92423x 4 38 ethical ethical ADJ rb68x92423x 4 39 controversy controversy NOUN rb68x92423x 4 40 in in ADP rb68x92423x 4 41 using use VERB rb68x92423x 4 42 the the DET rb68x92423x 4 43 animal animal NOUN rb68x92423x 4 44 models model NOUN rb68x92423x 4 45 . . PUNCT rb68x92423x 5 1 current current ADJ rb68x92423x 5 2 in in ADP rb68x92423x 5 3 vitro vitro X rb68x92423x 5 4 tissue tissue NOUN rb68x92423x 5 5 models model NOUN rb68x92423x 5 6 utilize utilize VERB rb68x92423x 5 7 various various ADJ rb68x92423x 5 8 methods method NOUN rb68x92423x 5 9 to to PART rb68x92423x 5 10 combine combine VERB rb68x92423x 5 11 biological biological ADJ rb68x92423x 5 12 scaffolds scaffold NOUN rb68x92423x 5 13 , , PUNCT rb68x92423x 5 14 hydrogels hydrogel NOUN rb68x92423x 5 15 , , PUNCT rb68x92423x 5 16 or or CCONJ rb68x92423x 5 17 decellularized decellularized ADJ rb68x92423x 5 18 matrices matrix NOUN rb68x92423x 5 19 with with ADP rb68x92423x 5 20 cardiac cardiac ADJ rb68x92423x 5 21 cells cell NOUN rb68x92423x 5 22 , , PUNCT rb68x92423x 5 23 to to PART rb68x92423x 5 24 provide provide VERB rb68x92423x 5 25 them they PRON rb68x92423x 5 26 with with ADP rb68x92423x 5 27 a a DET rb68x92423x 5 28 3d 3d NOUN rb68x92423x 5 29 microenvironment microenvironment NOUN rb68x92423x 5 30 that that PRON rb68x92423x 5 31 mimics mimic VERB rb68x92423x 5 32 the the DET rb68x92423x 5 33 native native ADJ rb68x92423x 5 34 cardiac cardiac ADJ rb68x92423x 5 35 tissue tissue NOUN rb68x92423x 5 36 . . PUNCT rb68x92423x 6 1 three three NUM rb68x92423x 6 2 dimensional dimensional ADJ rb68x92423x 6 3 ( ( PUNCT rb68x92423x 6 4 3d 3d NOUN rb68x92423x 6 5 ) ) PUNCT rb68x92423x 6 6 bioprinting bioprinting NOUN rb68x92423x 6 7 is be AUX rb68x92423x 6 8 a a DET rb68x92423x 6 9 layer layer NOUN rb68x92423x 6 10 - - PUNCT rb68x92423x 6 11 by by ADP rb68x92423x 6 12 - - PUNCT rb68x92423x 6 13 layer layer NOUN rb68x92423x 6 14 additive additive ADJ rb68x92423x 6 15 manufacturing manufacturing NOUN rb68x92423x 6 16 technology technology NOUN rb68x92423x 6 17 allowing allow VERB rb68x92423x 6 18 accurate accurate ADJ rb68x92423x 6 19 spatial spatial ADJ rb68x92423x 6 20 deposition deposition NOUN rb68x92423x 6 21 of of ADP rb68x92423x 6 22 the the DET rb68x92423x 6 23 biological biological ADJ rb68x92423x 6 24 materials material NOUN rb68x92423x 6 25 and and CCONJ rb68x92423x 6 26 active active ADJ rb68x92423x 6 27 cells cell NOUN rb68x92423x 6 28 in in ADP rb68x92423x 6 29 a a DET rb68x92423x 6 30 pre pre ADJ rb68x92423x 6 31 - - ADJ rb68x92423x 6 32 designed design VERB rb68x92423x 6 33 pattern pattern NOUN rb68x92423x 6 34 and and CCONJ rb68x92423x 6 35 is be AUX rb68x92423x 6 36 thus thus ADV rb68x92423x 6 37 considered consider VERB rb68x92423x 6 38 a a DET rb68x92423x 6 39 promising promising ADJ rb68x92423x 6 40 technique technique NOUN rb68x92423x 6 41 for for ADP rb68x92423x 6 42 fabricating fabricate VERB rb68x92423x 6 43 biomimetic biomimetic ADJ rb68x92423x 6 44 cardiac cardiac ADJ rb68x92423x 6 45 tissue tissue NOUN rb68x92423x 6 46 models model NOUN rb68x92423x 6 47 in in ADP rb68x92423x 6 48 vitro.the vitro.the DET rb68x92423x 6 49 scope scope NOUN rb68x92423x 6 50 of of ADP rb68x92423x 6 51 this this DET rb68x92423x 6 52 dissertation dissertation NOUN rb68x92423x 6 53 is be AUX rb68x92423x 6 54 to to PART rb68x92423x 6 55 develop develop VERB rb68x92423x 6 56 novel novel ADJ rb68x92423x 6 57 bioinks bioink NOUN rb68x92423x 6 58 and and CCONJ rb68x92423x 6 59 methodologies methodology NOUN rb68x92423x 6 60 for for ADP rb68x92423x 6 61 extrusion extrusion NOUN rb68x92423x 6 62 - - PUNCT rb68x92423x 6 63 based base VERB rb68x92423x 6 64 3d 3d NOUN rb68x92423x 6 65 bioprinting bioprinting NOUN rb68x92423x 6 66 to to PART rb68x92423x 6 67 engineer engineer VERB rb68x92423x 6 68 more more ADV rb68x92423x 6 69 biomimetic biomimetic ADJ rb68x92423x 6 70 post post ADJ rb68x92423x 6 71 - - ADJ rb68x92423x 6 72 mi mi ADJ rb68x92423x 6 73 tissue tissue NOUN rb68x92423x 6 74 models model NOUN rb68x92423x 6 75 as as ADV rb68x92423x 6 76 well well ADV rb68x92423x 6 77 as as ADP rb68x92423x 6 78 promising promise VERB rb68x92423x 6 79 regenerative regenerative ADJ rb68x92423x 6 80 therapies therapy NOUN rb68x92423x 6 81 that that PRON rb68x92423x 6 82 can can AUX rb68x92423x 6 83 be be AUX rb68x92423x 6 84 used use VERB rb68x92423x 6 85 to to PART rb68x92423x 6 86 treat treat VERB rb68x92423x 6 87 cardiac cardiac ADJ rb68x92423x 6 88 fibrosis fibrosis NOUN rb68x92423x 6 89 replacing replace VERB rb68x92423x 6 90 the the DET rb68x92423x 6 91 healthy healthy ADJ rb68x92423x 6 92 myocardium myocardium NOUN rb68x92423x 6 93 post post NOUN rb68x92423x 6 94 - - NOUN rb68x92423x 6 95 mi mi ADJ rb68x92423x 6 96 . . PROPN rb68x92423x 6 97 towards towards ADP rb68x92423x 6 98 this this DET rb68x92423x 6 99 goal goal NOUN rb68x92423x 6 100 , , PUNCT rb68x92423x 6 101 first first ADV rb68x92423x 6 102 i i PRON rb68x92423x 6 103 develop develop VERB rb68x92423x 6 104 a a DET rb68x92423x 6 105 novel novel ADJ rb68x92423x 6 106 two two NUM rb68x92423x 6 107 - - PUNCT rb68x92423x 6 108 step step NOUN rb68x92423x 6 109 crosslinking crosslinke VERB rb68x92423x 6 110 method method NOUN rb68x92423x 6 111 to to PART rb68x92423x 6 112 crosslink crosslink VERB rb68x92423x 6 113 gelatin gelatin NOUN rb68x92423x 6 114 methacryloyl methacryloyl PROPN rb68x92423x 6 115 ( ( PUNCT rb68x92423x 6 116 gelma gelma PROPN rb68x92423x 6 117 ) ) PUNCT rb68x92423x 6 118 hydrogels hydrogel NOUN rb68x92423x 6 119 , , PUNCT rb68x92423x 6 120 which which PRON rb68x92423x 6 121 can can AUX rb68x92423x 6 122 be be AUX rb68x92423x 6 123 used use VERB rb68x92423x 6 124 to to PART rb68x92423x 6 125 imitate imitate VERB rb68x92423x 6 126 the the DET rb68x92423x 6 127 relative relative ADJ rb68x92423x 6 128 stiffening stiffening NOUN rb68x92423x 6 129 of of ADP rb68x92423x 6 130 the the DET rb68x92423x 6 131 fibrotic fibrotic ADJ rb68x92423x 6 132 tissue tissue NOUN rb68x92423x 6 133 compared compare VERB rb68x92423x 6 134 to to ADP rb68x92423x 6 135 the the DET rb68x92423x 6 136 healthy healthy ADJ rb68x92423x 6 137 heart heart NOUN rb68x92423x 6 138 tissue tissue NOUN rb68x92423x 6 139 . . PUNCT rb68x92423x 7 1 i i PRON rb68x92423x 7 2 investigated investigate VERB rb68x92423x 7 3 the the DET rb68x92423x 7 4 effect effect NOUN rb68x92423x 7 5 of of ADP rb68x92423x 7 6 this this DET rb68x92423x 7 7 crosslinking crosslinke VERB rb68x92423x 7 8 method method NOUN rb68x92423x 7 9 on on ADP rb68x92423x 7 10 mechanical mechanical ADJ rb68x92423x 7 11 and and CCONJ rb68x92423x 7 12 rheological rheological ADJ rb68x92423x 7 13 properties property NOUN rb68x92423x 7 14 of of ADP rb68x92423x 7 15 gelma gelma NOUN rb68x92423x 7 16 hydrogels hydrogel NOUN rb68x92423x 7 17 as as ADV rb68x92423x 7 18 well well ADV rb68x92423x 7 19 as as ADP rb68x92423x 7 20 the the DET rb68x92423x 7 21 pattern pattern NOUN rb68x92423x 7 22 fidelity fidelity NOUN rb68x92423x 7 23 of of ADP rb68x92423x 7 24 the the DET rb68x92423x 7 25 3d 3d NOUN rb68x92423x 7 26 bioprinted bioprinte VERB rb68x92423x 7 27 constructs construct NOUN rb68x92423x 7 28 . . PUNCT rb68x92423x 8 1 then then ADV rb68x92423x 8 2 , , PUNCT rb68x92423x 8 3 i i PRON rb68x92423x 8 4 develop develop VERB rb68x92423x 8 5 novel novel ADJ rb68x92423x 8 6 bioinks bioink NOUN rb68x92423x 8 7 by by ADP rb68x92423x 8 8 combining combine VERB rb68x92423x 8 9 decellularized decellularize VERB rb68x92423x 8 10 human human ADJ rb68x92423x 8 11 myocardium myocardium NOUN rb68x92423x 8 12 extracellular extracellular ADJ rb68x92423x 8 13 matrix matrix NOUN rb68x92423x 8 14 ( ( PUNCT rb68x92423x 8 15 dhecm dhecm NOUN rb68x92423x 8 16 ) ) PUNCT rb68x92423x 8 17 with with ADP rb68x92423x 8 18 either either CCONJ rb68x92423x 8 19 gelma gelma NOUN rb68x92423x 8 20 hydrogels hydrogel NOUN rb68x92423x 8 21 or or CCONJ rb68x92423x 8 22 gelma gelma NOUN rb68x92423x 8 23 and and CCONJ rb68x92423x 8 24 methacrylated methacrylate VERB rb68x92423x 8 25 hyaluronic hyaluronic NOUN rb68x92423x 8 26 acid acid NOUN rb68x92423x 8 27 ( ( PUNCT rb68x92423x 8 28 meha meha NOUN rb68x92423x 8 29 ) ) PUNCT rb68x92423x 8 30 hydrogels hydrogel NOUN rb68x92423x 8 31 to to PART rb68x92423x 8 32 create create VERB rb68x92423x 8 33 the the DET rb68x92423x 8 34 softer soft ADJ rb68x92423x 8 35 healthy healthy ADJ rb68x92423x 8 36 cardiac cardiac ADJ rb68x92423x 8 37 tissue tissue NOUN rb68x92423x 8 38 or or CCONJ rb68x92423x 8 39 the the DET rb68x92423x 8 40 scar scar ADJ rb68x92423x 8 41 tissue tissue NOUN rb68x92423x 8 42 having have VERB rb68x92423x 8 43 an an DET rb68x92423x 8 44 order order NOUN rb68x92423x 8 45 of of ADP rb68x92423x 8 46 magnitude magnitude NOUN rb68x92423x 8 47 higher high ADJ rb68x92423x 8 48 stiffness stiffness NOUN rb68x92423x 8 49 compared compare VERB rb68x92423x 8 50 to to ADP rb68x92423x 8 51 the the DET rb68x92423x 8 52 healthy healthy ADJ rb68x92423x 8 53 tissue tissue NOUN rb68x92423x 8 54 . . PUNCT rb68x92423x 9 1 i i PRON rb68x92423x 9 2 then then ADV rb68x92423x 9 3 characterize characterize VERB rb68x92423x 9 4 the the DET rb68x92423x 9 5 mechanical mechanical ADJ rb68x92423x 9 6 , , PUNCT rb68x92423x 9 7 rheological rheological ADJ rb68x92423x 9 8 and and CCONJ rb68x92423x 9 9 physical physical ADJ rb68x92423x 9 10 properties property NOUN rb68x92423x 9 11 of of ADP rb68x92423x 9 12 these these DET rb68x92423x 9 13 bioinks bioink NOUN rb68x92423x 9 14 as as ADV rb68x92423x 9 15 well well ADV rb68x92423x 9 16 as as ADP rb68x92423x 9 17 their their PRON rb68x92423x 9 18 cytotoxicity cytotoxicity NOUN rb68x92423x 9 19 and and CCONJ rb68x92423x 9 20 printability printability NOUN rb68x92423x 9 21 . . PUNCT rb68x92423x 10 1 as as ADP rb68x92423x 10 2 a a DET rb68x92423x 10 3 proof proof NOUN rb68x92423x 10 4 of of ADP rb68x92423x 10 5 concept concept NOUN rb68x92423x 10 6 , , PUNCT rb68x92423x 10 7 i i PRON rb68x92423x 10 8 combined combine VERB rb68x92423x 10 9 human human ADV rb68x92423x 10 10 induced induce VERB rb68x92423x 10 11 pluripotent pluripotent ADJ rb68x92423x 10 12 stem stem NOUN rb68x92423x 10 13 cell cell NOUN rb68x92423x 10 14 ( ( PUNCT rb68x92423x 10 15 hipsc hipsc NOUN rb68x92423x 10 16 ) ) PUNCT rb68x92423x 10 17 derived derive VERB rb68x92423x 10 18 cardiomyocytes cardiomyocyte NOUN rb68x92423x 10 19 ( ( PUNCT rb68x92423x 10 20 icms icms NOUN rb68x92423x 10 21 ) ) PUNCT rb68x92423x 10 22 with with ADP rb68x92423x 10 23 gelma gelma NOUN rb68x92423x 10 24 - - PUNCT rb68x92423x 10 25 dhecm dhecm NOUN rb68x92423x 10 26 to to PART rb68x92423x 10 27 represent represent VERB rb68x92423x 10 28 the the DET rb68x92423x 10 29 healthy healthy ADJ rb68x92423x 10 30 tissue tissue NOUN rb68x92423x 10 31 and and CCONJ rb68x92423x 10 32 human human ADJ rb68x92423x 10 33 cardiac cardiac ADJ rb68x92423x 10 34 fibroblasts(hcfs fibroblasts(hcfs PROPN rb68x92423x 10 35 ) ) PUNCT rb68x92423x 10 36 with with ADP rb68x92423x 10 37 gelma gelma NOUN rb68x92423x 10 38 - - PUNCT rb68x92423x 10 39 meha meha NOUN rb68x92423x 10 40 - - PUNCT rb68x92423x 10 41 dhecm dhecm NOUN rb68x92423x 10 42 to to PART rb68x92423x 10 43 represent represent VERB rb68x92423x 10 44 the the DET rb68x92423x 10 45 stiffer stiff ADJ rb68x92423x 10 46 scar scar ADJ rb68x92423x 10 47 tissue tissue NOUN rb68x92423x 10 48 . . PUNCT rb68x92423x 11 1 then then ADV rb68x92423x 11 2 i i PRON rb68x92423x 11 3 improve improve VERB rb68x92423x 11 4 the the DET rb68x92423x 11 5 complexity complexity NOUN rb68x92423x 11 6 of of ADP rb68x92423x 11 7 the the DET rb68x92423x 11 8 post post ADJ rb68x92423x 11 9 - - ADJ rb68x92423x 11 10 mi mi ADJ rb68x92423x 11 11 tissue tissue NOUN rb68x92423x 11 12 model model NOUN rb68x92423x 11 13 by by ADP rb68x92423x 11 14 introducing introduce VERB rb68x92423x 11 15 the the DET rb68x92423x 11 16 boundary boundary ADJ rb68x92423x 11 17 region region NOUN rb68x92423x 11 18 between between ADP rb68x92423x 11 19 the the DET rb68x92423x 11 20 healthy healthy ADJ rb68x92423x 11 21 and and CCONJ rb68x92423x 11 22 the the DET rb68x92423x 11 23 scar scar ADJ rb68x92423x 11 24 regions region NOUN rb68x92423x 11 25 together together ADV rb68x92423x 11 26 with with ADP rb68x92423x 11 27 including include VERB rb68x92423x 11 28 aged aged ADJ rb68x92423x 11 29 collagen collagen NOUN rb68x92423x 11 30 in in ADP rb68x92423x 11 31 order order NOUN rb68x92423x 11 32 to to PART rb68x92423x 11 33 take take VERB rb68x92423x 11 34 into into ADP rb68x92423x 11 35 consideration consideration NOUN rb68x92423x 11 36 the the DET rb68x92423x 11 37 aged aged ADJ rb68x92423x 11 38 microenvironment microenvironment NOUN rb68x92423x 11 39 . . PUNCT rb68x92423x 12 1 moreover moreover ADV rb68x92423x 12 2 , , PUNCT rb68x92423x 12 3 i i PRON rb68x92423x 12 4 increase increase VERB rb68x92423x 12 5 the the DET rb68x92423x 12 6 cell cell NOUN rb68x92423x 12 7 diversity diversity NOUN rb68x92423x 12 8 by by ADP rb68x92423x 12 9 using use VERB rb68x92423x 12 10 icms icms NOUN rb68x92423x 12 11 , , PUNCT rb68x92423x 12 12 hipsc hipsc PROPN rb68x92423x 12 13 derived derive VERB rb68x92423x 12 14 cardiac cardiac ADJ rb68x92423x 12 15 fibroblasts fibroblast NOUN rb68x92423x 12 16 ( ( PUNCT rb68x92423x 12 17 icfs icfs PROPN rb68x92423x 12 18 ) ) PUNCT rb68x92423x 12 19 , , PUNCT rb68x92423x 12 20 hipsc hipsc PROPN rb68x92423x 12 21 derived derive VERB rb68x92423x 12 22 endothelial endothelial ADJ rb68x92423x 12 23 cells cell NOUN rb68x92423x 12 24 ( ( PUNCT rb68x92423x 12 25 iecs iecs PROPN rb68x92423x 12 26 ) ) PUNCT rb68x92423x 12 27 and and CCONJ rb68x92423x 12 28 hipsc hipsc PROPN rb68x92423x 12 29 derived derive VERB rb68x92423x 12 30 cardiac cardiac ADJ rb68x92423x 12 31 myofibroblasts myofibroblast NOUN rb68x92423x 12 32 ( ( PUNCT rb68x92423x 12 33 icmfs icmfs PROPN rb68x92423x 12 34 ) ) PUNCT rb68x92423x 12 35 . . PUNCT rb68x92423x 13 1 the the DET rb68x92423x 13 2 method method NOUN rb68x92423x 13 3 i i PRON rb68x92423x 13 4 introduce introduce VERB rb68x92423x 13 5 here here ADV rb68x92423x 13 6 will will AUX rb68x92423x 13 7 allow allow VERB rb68x92423x 13 8 researchers researcher NOUN rb68x92423x 13 9 to to PART rb68x92423x 13 10 create create VERB rb68x92423x 13 11 patient patient NOUN rb68x92423x 13 12 - - PUNCT rb68x92423x 13 13 specific specific ADJ rb68x92423x 13 14 , , PUNCT rb68x92423x 13 15 age age NOUN rb68x92423x 13 16 - - PUNCT rb68x92423x 13 17 specific specific ADJ rb68x92423x 13 18 , , PUNCT rb68x92423x 13 19 benchtop benchtop NOUN rb68x92423x 13 20 , , PUNCT rb68x92423x 13 21 post post ADJ rb68x92423x 13 22 - - ADJ rb68x92423x 13 23 mi mi ADJ rb68x92423x 13 24 tissue tissue NOUN rb68x92423x 13 25 models model NOUN rb68x92423x 13 26 that that PRON rb68x92423x 13 27 can can AUX rb68x92423x 13 28 be be AUX rb68x92423x 13 29 used use VERB rb68x92423x 13 30 as as ADP rb68x92423x 13 31 a a DET rb68x92423x 13 32 platform platform NOUN rb68x92423x 13 33 to to PART rb68x92423x 13 34 evaluate evaluate VERB rb68x92423x 13 35 the the DET rb68x92423x 13 36 efficacy efficacy NOUN rb68x92423x 13 37 of of ADP rb68x92423x 13 38 novel novel ADJ rb68x92423x 13 39 regenerative regenerative ADJ rb68x92423x 13 40 therapies therapy NOUN rb68x92423x 13 41 before before ADP rb68x92423x 13 42 animal animal NOUN rb68x92423x 13 43 studies study NOUN rb68x92423x 13 44 or or CCONJ rb68x92423x 13 45 clinical clinical ADJ rb68x92423x 13 46 trials trial NOUN rb68x92423x 13 47 . . PUNCT rb68x92423x 14 1 finally finally ADV rb68x92423x 14 2 , , PUNCT rb68x92423x 14 3 we we PRON rb68x92423x 14 4 utilize utilize VERB rb68x92423x 14 5 aerosol aerosol ADJ rb68x92423x 14 6 jet jet NOUN rb68x92423x 14 7 printing printing NOUN rb68x92423x 14 8 to to PART rb68x92423x 14 9 create create VERB rb68x92423x 14 10 conductive conductive ADJ rb68x92423x 14 11 cardiac cardiac ADJ rb68x92423x 14 12 patches patch NOUN rb68x92423x 14 13 allowing allow VERB rb68x92423x 14 14 cell cell NOUN rb68x92423x 14 15 - - PUNCT rb68x92423x 14 16 level level NOUN rb68x92423x 14 17 resolution resolution NOUN rb68x92423x 14 18 enabling enable VERB rb68x92423x 14 19 the the DET rb68x92423x 14 20 alignment alignment NOUN rb68x92423x 14 21 of of ADP rb68x92423x 14 22 the the DET rb68x92423x 14 23 icms icms NOUN rb68x92423x 14 24 on on ADP rb68x92423x 14 25 the the DET rb68x92423x 14 26 hydrogel hydrogel NOUN rb68x92423x 14 27 similar similar ADJ rb68x92423x 14 28 to to ADP rb68x92423x 14 29 the the DET rb68x92423x 14 30 native native ADJ rb68x92423x 14 31 heart heart NOUN rb68x92423x 14 32 tissue tissue NOUN rb68x92423x 14 33 . . PUNCT rb68x92423x 15 1 overall overall ADV rb68x92423x 15 2 , , PUNCT rb68x92423x 15 3 in in ADP rb68x92423x 15 4 this this DET rb68x92423x 15 5 dissertation dissertation NOUN rb68x92423x 15 6 i i PRON rb68x92423x 15 7 develop develop VERB rb68x92423x 15 8 new new ADJ rb68x92423x 15 9 bioinks bioink NOUN rb68x92423x 15 10 and and CCONJ rb68x92423x 15 11 methods method NOUN rb68x92423x 15 12 to to PART rb68x92423x 15 13 utilize utilize VERB rb68x92423x 15 14 3d 3d NOUN rb68x92423x 15 15 bioprinting bioprinting NOUN rb68x92423x 15 16 in in ADP rb68x92423x 15 17 various various ADJ rb68x92423x 15 18 cardiac cardiac ADJ rb68x92423x 15 19 tissue tissue NOUN rb68x92423x 15 20 engineering engineering NOUN rb68x92423x 15 21 applications application NOUN rb68x92423x 15 22 , , PUNCT rb68x92423x 15 23 such such ADJ rb68x92423x 15 24 as as ADP rb68x92423x 15 25 post post ADJ rb68x92423x 15 26 - - ADJ rb68x92423x 15 27 mi mi ADJ rb68x92423x 15 28 tissue tissue NOUN rb68x92423x 15 29 models model NOUN rb68x92423x 15 30 and and CCONJ rb68x92423x 15 31 cardiac cardiac ADJ rb68x92423x 15 32 patches patch NOUN rb68x92423x 15 33 , , PUNCT rb68x92423x 15 34 which which PRON rb68x92423x 15 35 can can AUX rb68x92423x 15 36 be be AUX rb68x92423x 15 37 used use VERB rb68x92423x 15 38 as as ADP rb68x92423x 15 39 a a DET rb68x92423x 15 40 guide guide NOUN rb68x92423x 15 41 for for ADP rb68x92423x 15 42 developing develop VERB rb68x92423x 15 43 new new ADJ rb68x92423x 15 44 models model NOUN rb68x92423x 15 45 and and CCONJ rb68x92423x 15 46 treatment treatment NOUN rb68x92423x 15 47 strategies strategy NOUN rb68x92423x 15 48 . . PUNCT