id sid tid token lemma pos qf85n873d1n 1 1 in in ADP qf85n873d1n 1 2 this this DET qf85n873d1n 1 3 thesis thesis NOUN qf85n873d1n 1 4 , , PUNCT qf85n873d1n 1 5 the the DET qf85n873d1n 1 6 importance importance NOUN qf85n873d1n 1 7 of of ADP qf85n873d1n 1 8 rare rare ADJ qf85n873d1n 1 9 codons codon NOUN qf85n873d1n 1 10 on on ADP qf85n873d1n 1 11 protein protein NOUN qf85n873d1n 1 12 biogenesis biogenesis NOUN qf85n873d1n 1 13 as as ADV qf85n873d1n 1 14 well well ADV qf85n873d1n 1 15 as as ADP qf85n873d1n 1 16 cell cell NOUN qf85n873d1n 1 17 fitness fitness NOUN qf85n873d1n 1 18 will will AUX qf85n873d1n 1 19 be be AUX qf85n873d1n 1 20 discussed discuss VERB qf85n873d1n 1 21 . . PUNCT qf85n873d1n 2 1 to to PART qf85n873d1n 2 2 test test VERB qf85n873d1n 2 3 the the DET qf85n873d1n 2 4 effects effect NOUN qf85n873d1n 2 5 of of ADP qf85n873d1n 2 6 rare rare ADJ qf85n873d1n 2 7 codons codon NOUN qf85n873d1n 2 8 , , PUNCT qf85n873d1n 2 9 a a DET qf85n873d1n 2 10 continuous continuous ADJ qf85n873d1n 2 11 cell cell NOUN qf85n873d1n 2 12 culture culture NOUN qf85n873d1n 2 13 device device NOUN qf85n873d1n 2 14 known know VERB qf85n873d1n 2 15 as as ADP qf85n873d1n 2 16 a a DET qf85n873d1n 2 17 turbidostat turbidostat NOUN qf85n873d1n 2 18 was be AUX qf85n873d1n 2 19 built build VERB qf85n873d1n 2 20 and and CCONJ qf85n873d1n 2 21 optimized optimize VERB qf85n873d1n 2 22 within within ADP qf85n873d1n 2 23 the the DET qf85n873d1n 2 24 lab lab NOUN qf85n873d1n 2 25 . . PUNCT qf85n873d1n 3 1 the the DET qf85n873d1n 3 2 turbidostat turbidostat PROPN qf85n873d1n 3 3 , , PUNCT qf85n873d1n 3 4 as as ADV qf85n873d1n 3 5 well well ADV qf85n873d1n 3 6 as as ADP qf85n873d1n 3 7 batch batch NOUN qf85n873d1n 3 8 culture culture NOUN qf85n873d1n 3 9 , , PUNCT qf85n873d1n 3 10 is be AUX qf85n873d1n 3 11 used use VERB qf85n873d1n 3 12 to to PART qf85n873d1n 3 13 test test VERB qf85n873d1n 3 14 the the DET qf85n873d1n 3 15 extent extent NOUN qf85n873d1n 3 16 to to PART qf85n873d1n 3 17 which which PRON qf85n873d1n 3 18 rare rare ADJ qf85n873d1n 3 19 codons codon NOUN qf85n873d1n 3 20 affect affect VERB qf85n873d1n 3 21 an an DET qf85n873d1n 3 22 antibiotic antibiotic ADJ qf85n873d1n 3 23 resistance resistance NOUN qf85n873d1n 3 24 protein protein NOUN qf85n873d1n 3 25 known know VERB qf85n873d1n 3 26 as as ADP qf85n873d1n 3 27 chloramphenicol chloramphenicol NOUN qf85n873d1n 3 28 acetyltransferase acetyltransferase NOUN qf85n873d1n 3 29 ( ( PUNCT qf85n873d1n 3 30 cat cat NOUN qf85n873d1n 3 31 ) ) PUNCT qf85n873d1n 3 32 . . PUNCT qf85n873d1n 4 1 cat cat NOUN qf85n873d1n 4 2 has have VERB qf85n873d1n 4 3 three three NUM qf85n873d1n 4 4 known know VERB qf85n873d1n 4 5 types type NOUN qf85n873d1n 4 6 ( ( PUNCT qf85n873d1n 4 7 i i PROPN qf85n873d1n 4 8 , , PUNCT qf85n873d1n 4 9 ii ii PROPN qf85n873d1n 4 10 , , PUNCT qf85n873d1n 4 11 and and CCONJ qf85n873d1n 4 12 iii iii X qf85n873d1n 4 13 ) ) PUNCT qf85n873d1n 4 14 , , PUNCT qf85n873d1n 4 15 and and CCONJ qf85n873d1n 4 16 is be AUX qf85n873d1n 4 17 responsible responsible ADJ qf85n873d1n 4 18 for for ADP qf85n873d1n 4 19 the the DET qf85n873d1n 4 20 acetylation acetylation NOUN qf85n873d1n 4 21 of of ADP qf85n873d1n 4 22 the the DET qf85n873d1n 4 23 antibiotic antibiotic ADJ qf85n873d1n 4 24 chloramphenicol chloramphenicol NOUN qf85n873d1n 4 25 . . PUNCT qf85n873d1n 5 1 there there PRON qf85n873d1n 5 2 are be VERB qf85n873d1n 5 3 two two NUM qf85n873d1n 5 4 main main ADJ qf85n873d1n 5 5 methods method NOUN qf85n873d1n 5 6 that that PRON qf85n873d1n 5 7 are be AUX qf85n873d1n 5 8 used use VERB qf85n873d1n 5 9 to to PART qf85n873d1n 5 10 test test VERB qf85n873d1n 5 11 the the DET qf85n873d1n 5 12 fitness fitness NOUN qf85n873d1n 5 13 effects effect NOUN qf85n873d1n 5 14 of of ADP qf85n873d1n 5 15 different different ADJ qf85n873d1n 5 16 cat cat NOUN qf85n873d1n 5 17 - - PUNCT qf85n873d1n 5 18 iii iii PROPN qf85n873d1n 5 19 constructs constructs PROPN qf85n873d1n 5 20 , , PUNCT qf85n873d1n 5 21 one one NUM qf85n873d1n 5 22 of of ADP qf85n873d1n 5 23 which which PRON qf85n873d1n 5 24 is be AUX qf85n873d1n 5 25 a a DET qf85n873d1n 5 26 competition competition NOUN qf85n873d1n 5 27 between between ADP qf85n873d1n 5 28 two two NUM qf85n873d1n 5 29 strains strain NOUN qf85n873d1n 5 30 , , PUNCT qf85n873d1n 5 31 and and CCONJ qf85n873d1n 5 32 the the DET qf85n873d1n 5 33 other other ADJ qf85n873d1n 5 34 is be AUX qf85n873d1n 5 35 a a DET qf85n873d1n 5 36 cat cat NOUN qf85n873d1n 5 37 assay assay ADJ qf85n873d1n 5 38 to to PART qf85n873d1n 5 39 directly directly ADV qf85n873d1n 5 40 measure measure VERB qf85n873d1n 5 41 chloramphenicol chloramphenicol NOUN qf85n873d1n 5 42 conversion conversion NOUN qf85n873d1n 5 43 rates rate NOUN qf85n873d1n 5 44 . . PUNCT