id	sid	tid	token	lemma	pos
p8418k74r1n	1	1	this	this	DET
p8418k74r1n	1	2	dissertation	dissertation	NOUN
p8418k74r1n	1	3	focuses	focus	VERB
p8418k74r1n	1	4	on	on	ADP
p8418k74r1n	1	5	the	the	DET
p8418k74r1n	1	6	development	development	NOUN
p8418k74r1n	1	7	of	of	ADP
p8418k74r1n	1	8	sheath	sheath	NOUN
p8418k74r1n	1	9	-	-	PUNCT
p8418k74r1n	1	10	flow	flow	NOUN
p8418k74r1n	1	11	surface	surface	NOUN
p8418k74r1n	1	12	enhanced	enhance	VERB
p8418k74r1n	1	13	raman	raman	NOUN
p8418k74r1n	1	14	(	(	PUNCT
p8418k74r1n	1	15	sers	ser	NOUN
p8418k74r1n	1	16	)	)	PUNCT
p8418k74r1n	1	17	detection	detection	NOUN
p8418k74r1n	1	18	for	for	ADP
p8418k74r1n	1	19	liquid	liquid	ADJ
p8418k74r1n	1	20	chromatography	chromatography	NOUN
p8418k74r1n	1	21	(	(	PUNCT
p8418k74r1n	1	22	lc	lc	NOUN
p8418k74r1n	1	23	)	)	PUNCT
p8418k74r1n	1	24	,	,	PUNCT
p8418k74r1n	1	25	to	to	PART
p8418k74r1n	1	26	enable	enable	VERB
p8418k74r1n	1	27	online	online	ADJ
p8418k74r1n	1	28	separation	separation	NOUN
p8418k74r1n	1	29	,	,	PUNCT
p8418k74r1n	1	30	detection	detection	NOUN
p8418k74r1n	1	31	and	and	CCONJ
p8418k74r1n	1	32	quantification	quantification	NOUN
p8418k74r1n	1	33	of	of	ADP
p8418k74r1n	1	34	biomolecules	biomolecule	NOUN
p8418k74r1n	1	35	at	at	ADP
p8418k74r1n	1	36	low	low	ADJ
p8418k74r1n	1	37	concentrations	concentration	NOUN
p8418k74r1n	1	38	in	in	ADP
p8418k74r1n	1	39	flow	flow	NOUN
p8418k74r1n	1	40	.	.	PUNCT
p8418k74r1n	2	1	the	the	DET
p8418k74r1n	2	2	experiments	experiment	NOUN
p8418k74r1n	2	3	reported	report	VERB
p8418k74r1n	2	4	here	here	ADV
p8418k74r1n	2	5	focused	focus	VERB
p8418k74r1n	2	6	on	on	ADP
p8418k74r1n	2	7	the	the	DET
p8418k74r1n	2	8	direct	direct	ADJ
p8418k74r1n	2	9	,	,	PUNCT
p8418k74r1n	2	10	label	label	NOUN
p8418k74r1n	2	11	-	-	PUNCT
p8418k74r1n	2	12	free	free	ADJ
p8418k74r1n	2	13	sers	ser	NOUN
p8418k74r1n	2	14	aspects	aspect	NOUN
p8418k74r1n	2	15	in	in	ADP
p8418k74r1n	2	16	analysis	analysis	NOUN
p8418k74r1n	2	17	and	and	CCONJ
p8418k74r1n	2	18	identification	identification	NOUN
p8418k74r1n	2	19	of	of	ADP
p8418k74r1n	2	20	small	small	ADJ
p8418k74r1n	2	21	biomolecules	biomolecule	NOUN
p8418k74r1n	2	22	.	.	PUNCT
p8418k74r1n	3	1	the	the	DET
p8418k74r1n	3	2	direct	direct	ADJ
p8418k74r1n	3	3	sers	ser	NOUN
p8418k74r1n	3	4	detection	detection	NOUN
p8418k74r1n	3	5	is	be	AUX
p8418k74r1n	3	6	very	very	ADV
p8418k74r1n	3	7	straight	straight	ADV
p8418k74r1n	3	8	forward	forward	ADV
p8418k74r1n	3	9	and	and	CCONJ
p8418k74r1n	3	10	has	have	AUX
p8418k74r1n	3	11	been	be	AUX
p8418k74r1n	3	12	reported	report	VERB
p8418k74r1n	3	13	to	to	PART
p8418k74r1n	3	14	be	be	AUX
p8418k74r1n	3	15	able	able	ADJ
p8418k74r1n	3	16	to	to	PART
p8418k74r1n	3	17	detect	detect	VERB
p8418k74r1n	3	18	different	different	ADJ
p8418k74r1n	3	19	classes	class	NOUN
p8418k74r1n	3	20	of	of	ADP
p8418k74r1n	3	21	biomolecules	biomolecule	NOUN
p8418k74r1n	3	22	ranging	range	VERB
p8418k74r1n	3	23	from	from	ADP
p8418k74r1n	3	24	nucleic	nucleic	ADJ
p8418k74r1n	3	25	acids	acid	NOUN
p8418k74r1n	3	26	,	,	PUNCT
p8418k74r1n	3	27	proteins	protein	NOUN
p8418k74r1n	3	28	,	,	PUNCT
p8418k74r1n	3	29	carbohydrates	carbohydrate	NOUN
p8418k74r1n	3	30	,	,	PUNCT
p8418k74r1n	3	31	and	and	CCONJ
p8418k74r1n	3	32	nucleotides	nucleotide	NOUN
p8418k74r1n	3	33	to	to	ADP
p8418k74r1n	3	34	small	small	ADJ
p8418k74r1n	3	35	molecule	molecule	NOUN
p8418k74r1n	3	36	metabolites	metabolite	NOUN
p8418k74r1n	3	37	.	.	PUNCT
p8418k74r1n	4	1	the	the	DET
p8418k74r1n	4	2	coupling	coupling	NOUN
p8418k74r1n	4	3	of	of	ADP
p8418k74r1n	4	4	lc	lc	NOUN
p8418k74r1n	4	5	-	-	PUNCT
p8418k74r1n	4	6	sers	ser	NOUN
p8418k74r1n	4	7	to	to	ADP
p8418k74r1n	4	8	a	a	DET
p8418k74r1n	4	9	lab	lab	NOUN
p8418k74r1n	4	10	-	-	PUNCT
p8418k74r1n	4	11	built	build	VERB
p8418k74r1n	4	12	flow	flow	NOUN
p8418k74r1n	4	13	cell	cell	NOUN
p8418k74r1n	4	14	using	use	VERB
p8418k74r1n	4	15	hydrodynamic	hydrodynamic	ADJ
p8418k74r1n	4	16	focusing	focusing	NOUN
p8418k74r1n	4	17	is	be	AUX
p8418k74r1n	4	18	reported	report	VERB
p8418k74r1n	4	19	.	.	PUNCT
p8418k74r1n	5	1	the	the	DET
p8418k74r1n	5	2	sers	ser	NOUN
p8418k74r1n	5	3	cell	cell	NOUN
p8418k74r1n	5	4	is	be	AUX
p8418k74r1n	5	5	connected	connect	VERB
p8418k74r1n	5	6	directly	directly	ADV
p8418k74r1n	5	7	with	with	ADP
p8418k74r1n	5	8	the	the	DET
p8418k74r1n	5	9	lc	lc	PROPN
p8418k74r1n	5	10	outlet	outlet	NOUN
p8418k74r1n	5	11	for	for	ADP
p8418k74r1n	5	12	simultaneous	simultaneous	ADJ
p8418k74r1n	5	13	post	post	ADJ
p8418k74r1n	5	14	-	-	ADJ
p8418k74r1n	5	15	separation	separation	ADJ
p8418k74r1n	5	16	detection	detection	NOUN
p8418k74r1n	5	17	.	.	PUNCT
p8418k74r1n	6	1	a	a	DET
p8418k74r1n	6	2	mixture	mixture	NOUN
p8418k74r1n	6	3	of	of	ADP
p8418k74r1n	6	4	model	model	NOUN
p8418k74r1n	6	5	metabolites	metabolite	NOUN
p8418k74r1n	6	6	(	(	PUNCT
p8418k74r1n	6	7	thiamine	thiamine	NOUN
p8418k74r1n	6	8	,	,	PUNCT
p8418k74r1n	6	9	folic	folic	NOUN
p8418k74r1n	6	10	acid	acid	NOUN
p8418k74r1n	6	11	,	,	PUNCT
p8418k74r1n	6	12	and	and	CCONJ
p8418k74r1n	6	13	riboflavin	riboflavin	NOUN
p8418k74r1n	6	14	)	)	PUNCT
p8418k74r1n	6	15	has	have	AUX
p8418k74r1n	6	16	been	be	AUX
p8418k74r1n	6	17	successfully	successfully	ADV
p8418k74r1n	6	18	separated	separate	VERB
p8418k74r1n	6	19	,	,	PUNCT
p8418k74r1n	6	20	characterized	characterize	VERB
p8418k74r1n	6	21	and	and	CCONJ
p8418k74r1n	6	22	quantified	quantify	VERB
p8418k74r1n	6	23	using	use	VERB
p8418k74r1n	6	24	acetonitrile	acetonitrile	NOUN
p8418k74r1n	6	25	in	in	ADP
p8418k74r1n	6	26	the	the	DET
p8418k74r1n	6	27	mobile	mobile	ADJ
p8418k74r1n	6	28	phase	phase	NOUN
p8418k74r1n	6	29	provides	provide	VERB
p8418k74r1n	6	30	an	an	DET
p8418k74r1n	6	31	internal	internal	ADJ
p8418k74r1n	6	32	standard	standard	NOUN
p8418k74r1n	6	33	.	.	PUNCT
p8418k74r1n	7	1	the	the	DET
p8418k74r1n	7	2	results	result	NOUN
p8418k74r1n	7	3	demonstrated	demonstrate	VERB
p8418k74r1n	7	4	that	that	SCONJ
p8418k74r1n	7	5	sheath	sheath	NOUN
p8418k74r1n	7	6	-	-	PUNCT
p8418k74r1n	7	7	flow	flow	NOUN
p8418k74r1n	7	8	sers	ser	NOUN
p8418k74r1n	7	9	is	be	AUX
p8418k74r1n	7	10	provides	provide	VERB
p8418k74r1n	7	11	improved	improved	ADJ
p8418k74r1n	7	12	detection	detection	NOUN
p8418k74r1n	7	13	of	of	ADP
p8418k74r1n	7	14	molecules	molecule	NOUN
p8418k74r1n	7	15	compared	compare	VERB
p8418k74r1n	7	16	to	to	ADP
p8418k74r1n	7	17	standard	standard	ADJ
p8418k74r1n	7	18	uv	uv	NOUN
p8418k74r1n	7	19	-	-	PUNCT
p8418k74r1n	7	20	vis	vis	X
p8418k74r1n	7	21	detectors	detector	NOUN
p8418k74r1n	7	22	.	.	PUNCT
p8418k74r1n	8	1	the	the	DET
p8418k74r1n	8	2	lc	lc	NOUN
p8418k74r1n	8	3	-	-	PUNCT
p8418k74r1n	8	4	sers	ser	NOUN
p8418k74r1n	8	5	system	system	NOUN
p8418k74r1n	8	6	has	have	AUX
p8418k74r1n	8	7	been	be	AUX
p8418k74r1n	8	8	further	far	ADV
p8418k74r1n	8	9	explored	explore	VERB
p8418k74r1n	8	10	to	to	PART
p8418k74r1n	8	11	detect	detect	VERB
p8418k74r1n	8	12	and	and	CCONJ
p8418k74r1n	8	13	quantify	quantify	VERB
p8418k74r1n	8	14	of	of	ADP
p8418k74r1n	8	15	three	three	NUM
p8418k74r1n	8	16	phosphorylated	phosphorylate	VERB
p8418k74r1n	8	17	carbohydrate	carbohydrate	NOUN
p8418k74r1n	8	18	molecules	molecule	NOUN
p8418k74r1n	8	19	:	:	PUNCT
p8418k74r1n	8	20	glucose	glucose	NOUN
p8418k74r1n	8	21	1	1	NUM
p8418k74r1n	8	22	-	-	PUNCT
p8418k74r1n	8	23	phosphate	phosphate	NOUN
p8418k74r1n	8	24	,	,	PUNCT
p8418k74r1n	8	25	glucose	glucose	NOUN
p8418k74r1n	8	26	6	6	NUM
p8418k74r1n	8	27	-	-	PUNCT
p8418k74r1n	8	28	phosphate	phosphate	NOUN
p8418k74r1n	8	29	and	and	CCONJ
p8418k74r1n	8	30	fructose	fructose	VERB
p8418k74r1n	8	31	6	6	NUM
p8418k74r1n	8	32	-	-	PUNCT
p8418k74r1n	8	33	phosphate	phosphate	NOUN
p8418k74r1n	8	34	.	.	PUNCT
p8418k74r1n	9	1	an	an	DET
p8418k74r1n	9	2	alkanethiol	alkanethiol	PROPN
p8418k74r1n	9	3	(	(	PUNCT
p8418k74r1n	9	4	hexanethiol	hexanethiol	PROPN
p8418k74r1n	9	5	)	)	PUNCT
p8418k74r1n	9	6	self	self	NOUN
p8418k74r1n	9	7	-	-	PUNCT
p8418k74r1n	9	8	assembled	assemble	VERB
p8418k74r1n	9	9	monolayer	monolayer	NOUN
p8418k74r1n	9	10	is	be	AUX
p8418k74r1n	9	11	formed	form	VERB
p8418k74r1n	9	12	over	over	ADP
p8418k74r1n	9	13	the	the	DET
p8418k74r1n	9	14	silver	silver	ADJ
p8418k74r1n	9	15	sers	ser	NOUN
p8418k74r1n	9	16	-	-	PUNCT
p8418k74r1n	9	17	active	active	ADJ
p8418k74r1n	9	18	substrate	substrate	NOUN
p8418k74r1n	9	19	helps	help	VERB
p8418k74r1n	9	20	retain	retain	VERB
p8418k74r1n	9	21	and	and	CCONJ
p8418k74r1n	9	22	concentrate	concentrate	VERB
p8418k74r1n	9	23	the	the	DET
p8418k74r1n	9	24	analytes	analyte	NOUN
p8418k74r1n	9	25	of	of	ADP
p8418k74r1n	9	26	interest	interest	NOUN
p8418k74r1n	9	27	at	at	ADP
p8418k74r1n	9	28	the	the	DET
p8418k74r1n	9	29	sers	ser	NOUN
p8418k74r1n	9	30	substrate	substrate	VERB
p8418k74r1n	9	31	to	to	PART
p8418k74r1n	9	32	improve	improve	VERB
p8418k74r1n	9	33	the	the	DET
p8418k74r1n	9	34	detection	detection	NOUN
p8418k74r1n	9	35	sensitivity	sensitivity	NOUN
p8418k74r1n	9	36	significantly	significantly	ADV
p8418k74r1n	9	37	.	.	PUNCT
p8418k74r1n	10	1	mixtures	mixture	NOUN
p8418k74r1n	10	2	of	of	ADP
p8418k74r1n	10	3	2	2	NUM
p8418k74r1n	10	4	µm	µm	NOUN
p8418k74r1n	10	5	of	of	ADP
p8418k74r1n	10	6	phosphorylated	phosphorylate	VERB
p8418k74r1n	10	7	carbohydrates	carbohydrate	NOUN
p8418k74r1n	10	8	in	in	ADP
p8418k74r1n	10	9	pure	pure	ADJ
p8418k74r1n	10	10	water	water	NOUN
p8418k74r1n	10	11	as	as	ADV
p8418k74r1n	10	12	well	well	ADV
p8418k74r1n	10	13	as	as	ADP
p8418k74r1n	10	14	in	in	ADP
p8418k74r1n	10	15	cell	cell	NOUN
p8418k74r1n	10	16	culture	culture	NOUN
p8418k74r1n	10	17	media	medium	NOUN
p8418k74r1n	10	18	were	be	AUX
p8418k74r1n	10	19	successfully	successfully	ADV
p8418k74r1n	10	20	separated	separate	VERB
p8418k74r1n	10	21	by	by	ADP
p8418k74r1n	10	22	hplc	hplc	NOUN
p8418k74r1n	10	23	,	,	PUNCT
p8418k74r1n	10	24	with	with	ADP
p8418k74r1n	10	25	identification	identification	NOUN
p8418k74r1n	10	26	using	use	VERB
p8418k74r1n	10	27	the	the	DET
p8418k74r1n	10	28	sheath	sheath	NOUN
p8418k74r1n	10	29	-	-	PUNCT
p8418k74r1n	10	30	flow	flow	NOUN
p8418k74r1n	10	31	sers	ser	NOUN
p8418k74r1n	10	32	detector	detector	NOUN
p8418k74r1n	10	33	.	.	PUNCT
p8418k74r1n	11	1	the	the	DET
p8418k74r1n	11	2	results	result	NOUN
p8418k74r1n	11	3	suggested	suggest	VERB
p8418k74r1n	11	4	a	a	DET
p8418k74r1n	11	5	tremendous	tremendous	ADJ
p8418k74r1n	11	6	potential	potential	NOUN
p8418k74r1n	11	7	for	for	ADP
p8418k74r1n	11	8	lc	lc	NOUN
p8418k74r1n	11	9	-	-	NOUN
p8418k74r1n	11	10	sers	ser	NOUN
p8418k74r1n	11	11	for	for	ADP
p8418k74r1n	11	12	targeted	target	VERB
p8418k74r1n	11	13	molecular	molecular	ADJ
p8418k74r1n	11	14	identification	identification	NOUN
p8418k74r1n	11	15	in	in	ADP
p8418k74r1n	11	16	complex	complex	ADJ
p8418k74r1n	11	17	biological	biological	ADJ
p8418k74r1n	11	18	environment	environment	NOUN
p8418k74r1n	11	19	for	for	ADP
p8418k74r1n	11	20	metabolomics	metabolomic	NOUN
p8418k74r1n	11	21	and	and	CCONJ
p8418k74r1n	11	22	other	other	ADJ
p8418k74r1n	11	23	bioanalytical	bioanalytical	ADJ
p8418k74r1n	11	24	studies.the	studies.the	DET
p8418k74r1n	11	25	excellent	excellent	ADJ
p8418k74r1n	11	26	sensitivity	sensitivity	NOUN
p8418k74r1n	11	27	of	of	ADP
p8418k74r1n	11	28	sheath	sheath	NOUN
p8418k74r1n	11	29	-	-	PUNCT
p8418k74r1n	11	30	flow	flow	NOUN
p8418k74r1n	11	31	sers	ser	NOUN
p8418k74r1n	11	32	has	have	AUX
p8418k74r1n	11	33	provided	provide	VERB
p8418k74r1n	11	34	a	a	DET
p8418k74r1n	11	35	new	new	ADJ
p8418k74r1n	11	36	detection	detection	NOUN
p8418k74r1n	11	37	technique	technique	NOUN
p8418k74r1n	11	38	for	for	ADP
p8418k74r1n	11	39	proteins	protein	NOUN
p8418k74r1n	11	40	study	study	NOUN
p8418k74r1n	11	41	.	.	PUNCT
p8418k74r1n	12	1	for	for	ADP
p8418k74r1n	12	2	instant	instant	NOUN
p8418k74r1n	12	3	,	,	PUNCT
p8418k74r1n	12	4	the	the	DET
p8418k74r1n	12	5	sheath	sheath	NOUN
p8418k74r1n	12	6	-	-	PUNCT
p8418k74r1n	12	7	flow	flow	NOUN
p8418k74r1n	12	8	sers	ser	NOUN
p8418k74r1n	12	9	has	have	AUX
p8418k74r1n	12	10	been	be	AUX
p8418k74r1n	12	11	successfully	successfully	ADV
p8418k74r1n	12	12	demonstrated	demonstrate	VERB
p8418k74r1n	12	13	to	to	PART
p8418k74r1n	12	14	decipher	decipher	VERB
p8418k74r1n	12	15	the	the	DET
p8418k74r1n	12	16	three	three	NUM
p8418k74r1n	12	17	different	different	ADJ
p8418k74r1n	12	18	small	small	ADJ
p8418k74r1n	12	19	ubiquitin	ubiquitin	NOUN
p8418k74r1n	12	20	like	like	ADP
p8418k74r1n	12	21	modifier	modifi	ADJ
p8418k74r1n	12	22	(	(	PUNCT
p8418k74r1n	12	23	sumo	sumo	NOUN
p8418k74r1n	12	24	)	)	PUNCT
p8418k74r1n	12	25	proteins	protein	NOUN
p8418k74r1n	12	26	of	of	ADP
p8418k74r1n	12	27	a	a	DET
p8418k74r1n	12	28	post	post	ADJ
p8418k74r1n	12	29	-	-	ADJ
p8418k74r1n	12	30	translational	translational	ADJ
p8418k74r1n	12	31	modifications	modification	NOUN
p8418k74r1n	12	32	process	process	NOUN
p8418k74r1n	12	33	of	of	ADP
p8418k74r1n	12	34	proteins	protein	NOUN
p8418k74r1n	12	35	known	know	VERB
p8418k74r1n	12	36	as	as	ADP
p8418k74r1n	12	37	the	the	DET
p8418k74r1n	12	38	sumoylation	sumoylation	NOUN
p8418k74r1n	12	39	.	.	PUNCT
p8418k74r1n	13	1	the	the	DET
p8418k74r1n	13	2	differentiation	differentiation	NOUN
p8418k74r1n	13	3	of	of	ADP
p8418k74r1n	13	4	three	three	NUM
p8418k74r1n	13	5	sumo	sumo	NOUN
p8418k74r1n	13	6	proteins	protein	NOUN
p8418k74r1n	13	7	was	be	AUX
p8418k74r1n	13	8	achieved	achieve	VERB
p8418k74r1n	13	9	in	in	ADP
p8418k74r1n	13	10	a	a	DET
p8418k74r1n	13	11	direct	direct	ADJ
p8418k74r1n	13	12	,	,	PUNCT
p8418k74r1n	13	13	label	label	NOUN
p8418k74r1n	13	14	-	-	PUNCT
p8418k74r1n	13	15	free	free	ADJ
p8418k74r1n	13	16	approach	approach	NOUN
p8418k74r1n	13	17	without	without	ADP
p8418k74r1n	13	18	the	the	DET
p8418k74r1n	13	19	need	need	NOUN
p8418k74r1n	13	20	of	of	ADP
p8418k74r1n	13	21	additional	additional	ADJ
p8418k74r1n	13	22	sample	sample	NOUN
p8418k74r1n	13	23	functionalization	functionalization	NOUN
p8418k74r1n	13	24	or	or	CCONJ
p8418k74r1n	13	25	affinity	affinity	NOUN
p8418k74r1n	13	26	reagents	reagent	NOUN
p8418k74r1n	13	27	.	.	PUNCT
p8418k74r1n	14	1	additionally	additionally	ADV
p8418k74r1n	14	2	,	,	PUNCT
p8418k74r1n	14	3	we	we	PRON
p8418k74r1n	14	4	demonstrate	demonstrate	VERB
p8418k74r1n	14	5	that	that	SCONJ
p8418k74r1n	14	6	the	the	DET
p8418k74r1n	14	7	identity	identity	NOUN
p8418k74r1n	14	8	of	of	ADP
p8418k74r1n	14	9	the	the	DET
p8418k74r1n	14	10	sumo	sumo	NOUN
p8418k74r1n	14	11	tag	tag	NOUN
p8418k74r1n	14	12	on	on	ADP
p8418k74r1n	14	13	a	a	DET
p8418k74r1n	14	14	protein	protein	NOUN
p8418k74r1n	14	15	can	can	AUX
p8418k74r1n	14	16	be	be	AUX
p8418k74r1n	14	17	determined	determine	VERB
p8418k74r1n	14	18	.	.	PUNCT