id sid tid token lemma pos ns064457m3b 1 1 a a DET ns064457m3b 1 2 method method NOUN ns064457m3b 1 3 utilizing utilize VERB ns064457m3b 1 4 catalytic catalytic ADJ ns064457m3b 1 5 titanocene titanocene ADJ ns064457m3b 1 6 dichloride dichloride NOUN ns064457m3b 1 7 for for ADP ns064457m3b 1 8 the the DET ns064457m3b 1 9 conjugate conjugate NOUN ns064457m3b 1 10 reduction reduction NOUN ns064457m3b 1 11 of of ADP ns064457m3b 1 12 & & CCONJ ns064457m3b 1 13 # # SYM ns064457m3b 1 14 945;,β-unsaturated 945;,β-unsaturated NUM ns064457m3b 1 15 carbonyls carbonyl NOUN ns064457m3b 1 16 was be AUX ns064457m3b 1 17 developed develop VERB ns064457m3b 1 18 and and CCONJ ns064457m3b 1 19 described describe VERB ns064457m3b 1 20 herein herein ADV ns064457m3b 1 21 . . PUNCT ns064457m3b 2 1 the the DET ns064457m3b 2 2 chemoselective chemoselective ADJ ns064457m3b 2 3 procedure procedure NOUN ns064457m3b 2 4 employs employ VERB ns064457m3b 2 5 an an DET ns064457m3b 2 6 amine amine NOUN ns064457m3b 2 7 hydrochloride hydrochloride NOUN ns064457m3b 2 8 as as ADP ns064457m3b 2 9 the the DET ns064457m3b 2 10 proton proton NOUN ns064457m3b 2 11 source source NOUN ns064457m3b 2 12 during during ADP ns064457m3b 2 13 the the DET ns064457m3b 2 14 catalytic catalytic ADJ ns064457m3b 2 15 modification modification NOUN ns064457m3b 2 16 as as SCONJ ns064457m3b 2 17 opposed oppose VERB ns064457m3b 2 18 to to ADP ns064457m3b 2 19 the the DET ns064457m3b 2 20 difficult difficult ADJ ns064457m3b 2 21 to to PART ns064457m3b 2 22 handle handle VERB ns064457m3b 2 23 and and CCONJ ns064457m3b 2 24 potentially potentially ADV ns064457m3b 2 25 explosive explosive ADJ ns064457m3b 2 26 h2 h2 NOUN ns064457m3b 2 27 atmosphere atmosphere NOUN ns064457m3b 2 28 . . PUNCT ns064457m3b 3 1 the the DET ns064457m3b 3 2 scope scope NOUN ns064457m3b 3 3 of of ADP ns064457m3b 3 4 conjugated conjugate VERB ns064457m3b 3 5 compounds compound NOUN ns064457m3b 3 6 includes include VERB ns064457m3b 3 7 cyclic cyclic ADJ ns064457m3b 3 8 and and CCONJ ns064457m3b 3 9 acyclic acyclic ADJ ns064457m3b 3 10 variations variation NOUN ns064457m3b 3 11 of of ADP ns064457m3b 3 12 ketones ketone NOUN ns064457m3b 3 13 , , PUNCT ns064457m3b 3 14 esters ester NOUN ns064457m3b 3 15 , , PUNCT ns064457m3b 3 16 aldehydes aldehyde NOUN ns064457m3b 3 17 , , PUNCT ns064457m3b 3 18 amides amide VERB ns064457m3b 3 19 , , PUNCT ns064457m3b 3 20 as as ADV ns064457m3b 3 21 well well ADV ns064457m3b 3 22 as as ADP ns064457m3b 3 23 ynones ynone NOUN ns064457m3b 3 24 , , PUNCT ns064457m3b 3 25 which which PRON ns064457m3b 3 26 contain contain VERB ns064457m3b 3 27 an an DET ns064457m3b 3 28 extra extra ADJ ns064457m3b 3 29 degree degree NOUN ns064457m3b 3 30 of of ADP ns064457m3b 3 31 unsaturation unsaturation NOUN ns064457m3b 3 32 . . PUNCT ns064457m3b 4 1 attempts attempt NOUN ns064457m3b 4 2 to to PART ns064457m3b 4 3 exploit exploit VERB ns064457m3b 4 4 the the DET ns064457m3b 4 5 utility utility NOUN ns064457m3b 4 6 of of ADP ns064457m3b 4 7 titanocene titanocene PROPN ns064457m3b 4 8 - - PUNCT ns064457m3b 4 9 bound bind VERB ns064457m3b 4 10 enolates enolate NOUN ns064457m3b 4 11 led lead VERB ns064457m3b 4 12 to to ADP ns064457m3b 4 13 the the DET ns064457m3b 4 14 discovery discovery NOUN ns064457m3b 4 15 of of ADP ns064457m3b 4 16 a a DET ns064457m3b 4 17 cp2ticl2 cp2ticl2 NOUN ns064457m3b 4 18 accelerated accelerate VERB ns064457m3b 4 19 organometallic organometallic ADJ ns064457m3b 4 20 formation formation NOUN ns064457m3b 4 21 . . PUNCT ns064457m3b 5 1 after after ADP ns064457m3b 5 2 a a DET ns064457m3b 5 3 detailed detailed ADJ ns064457m3b 5 4 investigation investigation NOUN ns064457m3b 5 5 by by ADP ns064457m3b 5 6 fleury fleury NOUN ns064457m3b 5 7 , , PUNCT ns064457m3b 5 8 catalytic catalytic ADJ ns064457m3b 5 9 loadings loading NOUN ns064457m3b 5 10 of of ADP ns064457m3b 5 11 titanium titanium NOUN ns064457m3b 5 12 as as ADV ns064457m3b 5 13 low low ADJ ns064457m3b 5 14 as as ADP ns064457m3b 5 15 1 1 NUM ns064457m3b 5 16 mol% mol% NOUN ns064457m3b 5 17 were be AUX ns064457m3b 5 18 demonstrated demonstrate VERB ns064457m3b 5 19 to to PART ns064457m3b 5 20 be be AUX ns064457m3b 5 21 effective effective ADJ ns064457m3b 5 22 at at ADP ns064457m3b 5 23 catalyzing catalyzing PROPN ns064457m3b 5 24 organozinc organozinc PROPN ns064457m3b 5 25 and and CCONJ ns064457m3b 5 26 organomagnesium organomagnesium NOUN ns064457m3b 5 27 reagents reagent NOUN ns064457m3b 5 28 derived derive VERB ns064457m3b 5 29 from from ADP ns064457m3b 5 30 allyl allyl NOUN ns064457m3b 5 31 , , PUNCT ns064457m3b 5 32 alkyl alkyl PROPN ns064457m3b 5 33 , , PUNCT ns064457m3b 5 34 aryl aryl NOUN ns064457m3b 5 35 , , PUNCT ns064457m3b 5 36 and and CCONJ ns064457m3b 5 37 vinyl vinyl NOUN ns064457m3b 5 38 species specie NOUN ns064457m3b 5 39 . . PUNCT ns064457m3b 6 1 subsequently subsequently ADV ns064457m3b 6 2 , , PUNCT ns064457m3b 6 3 a a DET ns064457m3b 6 4 novel novel ADJ ns064457m3b 6 5 phosphorus phosphorus NOUN ns064457m3b 6 6 redox redox NOUN ns064457m3b 6 7 process process NOUN ns064457m3b 6 8 was be AUX ns064457m3b 6 9 constructed construct VERB ns064457m3b 6 10 en en ADP ns064457m3b 6 11 route route NOUN ns064457m3b 6 12 to to ADP ns064457m3b 6 13 synthesizing synthesize VERB ns064457m3b 6 14 amides amide NOUN ns064457m3b 6 15 directly directly ADV ns064457m3b 6 16 from from ADP ns064457m3b 6 17 carboxylic carboxylic ADJ ns064457m3b 6 18 acids acid NOUN ns064457m3b 6 19 . . PUNCT ns064457m3b 7 1 the the DET ns064457m3b 7 2 dual dual ADJ ns064457m3b 7 3 role role NOUN ns064457m3b 7 4 of of ADP ns064457m3b 7 5 phosphorus phosphorus NOUN ns064457m3b 7 6 includes include VERB ns064457m3b 7 7 activation activation NOUN ns064457m3b 7 8 of of ADP ns064457m3b 7 9 the the DET ns064457m3b 7 10 carboxylic carboxylic ADJ ns064457m3b 7 11 acid acid NOUN ns064457m3b 7 12 for for ADP ns064457m3b 7 13 electrophilic electrophilic ADJ ns064457m3b 7 14 attack attack NOUN ns064457m3b 7 15 while while SCONJ ns064457m3b 7 16 decomposing decompose VERB ns064457m3b 7 17 an an DET ns064457m3b 7 18 azide azide NOUN ns064457m3b 7 19 to to PART ns064457m3b 7 20 reveal reveal VERB ns064457m3b 7 21 a a DET ns064457m3b 7 22 hidden hidden ADJ ns064457m3b 7 23 nucleophilic nucleophilic ADJ ns064457m3b 7 24 nitrogen nitrogen NOUN ns064457m3b 7 25 source source NOUN ns064457m3b 7 26 . . PUNCT ns064457m3b 8 1 the the DET ns064457m3b 8 2 resultant resultant ADJ ns064457m3b 8 3 array array NOUN ns064457m3b 8 4 of of ADP ns064457m3b 8 5 amides amide NOUN ns064457m3b 8 6 from from ADP ns064457m3b 8 7 this this DET ns064457m3b 8 8 process process NOUN ns064457m3b 8 9 includes include VERB ns064457m3b 8 10 alkyl alkyl NOUN ns064457m3b 8 11 , , PUNCT ns064457m3b 8 12 aryl aryl NOUN ns064457m3b 8 13 , , PUNCT ns064457m3b 8 14 and and CCONJ ns064457m3b 8 15 & & CCONJ ns064457m3b 8 16 # # SYM ns064457m3b 8 17 945;,β-unsaturated 945;,β-unsaturated NUM ns064457m3b 8 18 amides amide NOUN ns064457m3b 8 19 as as ADV ns064457m3b 8 20 well well ADV ns064457m3b 8 21 as as ADP ns064457m3b 8 22 lactams lactam NOUN ns064457m3b 8 23 and and CCONJ ns064457m3b 8 24 dipeptides dipeptide NOUN ns064457m3b 8 25 . . PUNCT ns064457m3b 9 1 as as ADP ns064457m3b 9 2 an an DET ns064457m3b 9 3 application application NOUN ns064457m3b 9 4 of of ADP ns064457m3b 9 5 the the DET ns064457m3b 9 6 highly highly ADV ns064457m3b 9 7 chemoselective chemoselective ADJ ns064457m3b 9 8 amidation amidation NOUN ns064457m3b 9 9 procedure procedure NOUN ns064457m3b 9 10 , , PUNCT ns064457m3b 9 11 a a DET ns064457m3b 9 12 synthesis synthesis NOUN ns064457m3b 9 13 of of ADP ns064457m3b 9 14 ly573636 ly573636 PROPN ns064457m3b 9 15 was be AUX ns064457m3b 9 16 completed complete VERB ns064457m3b 9 17 in in ADP ns064457m3b 9 18 3 3 NUM ns064457m3b 9 19 steps step NOUN ns064457m3b 9 20 from from ADP ns064457m3b 9 21 commercially commercially ADV ns064457m3b 9 22 available available ADJ ns064457m3b 9 23 starting start VERB ns064457m3b 9 24 materials material NOUN ns064457m3b 9 25 . . PUNCT ns064457m3b 10 1 this this DET ns064457m3b 10 2 unique unique ADJ ns064457m3b 10 3 aspect aspect NOUN ns064457m3b 10 4 of of ADP ns064457m3b 10 5 a a DET ns064457m3b 10 6 reagent reagent NOUN ns064457m3b 10 7 performing perform VERB ns064457m3b 10 8 two two NUM ns064457m3b 10 9 separate separate ADJ ns064457m3b 10 10 crucial crucial ADJ ns064457m3b 10 11 roles role NOUN ns064457m3b 10 12 was be AUX ns064457m3b 10 13 further far ADV ns064457m3b 10 14 advanced advance VERB ns064457m3b 10 15 by by ADP ns064457m3b 10 16 the the DET ns064457m3b 10 17 creation creation NOUN ns064457m3b 10 18 of of ADP ns064457m3b 10 19 the the DET ns064457m3b 10 20 first first ADJ ns064457m3b 10 21 staudinger staudinger PROPN ns064457m3b 10 22 ligation ligation NOUN ns064457m3b 10 23 catalytic catalytic ADJ ns064457m3b 10 24 in in ADP ns064457m3b 10 25 phosphine phosphine PROPN ns064457m3b 10 26 . . PUNCT ns064457m3b 11 1 a a DET ns064457m3b 11 2 diverse diverse ADJ ns064457m3b 11 3 assortment assortment NOUN ns064457m3b 11 4 of of ADP ns064457m3b 11 5 amides amide NOUN ns064457m3b 11 6 and and CCONJ ns064457m3b 11 7 imides imide NOUN ns064457m3b 11 8 can can AUX ns064457m3b 11 9 be be AUX ns064457m3b 11 10 produced produce VERB ns064457m3b 11 11 in in ADP ns064457m3b 11 12 moderate moderate ADJ ns064457m3b 11 13 to to ADP ns064457m3b 11 14 excellent excellent ADJ ns064457m3b 11 15 yields yield NOUN ns064457m3b 11 16 when when SCONJ ns064457m3b 11 17 using use VERB ns064457m3b 11 18 10 10 NUM ns064457m3b 11 19 mol% mol% PROPN ns064457m3b 11 20 ph3p ph3p PROPN ns064457m3b 11 21 and and CCONJ ns064457m3b 11 22 a a DET ns064457m3b 11 23 stoichiometric stoichiometric ADJ ns064457m3b 11 24 reductant reductant NOUN ns064457m3b 11 25 . . PUNCT ns064457m3b 12 1 these these DET ns064457m3b 12 2 catalytic catalytic ADJ ns064457m3b 12 3 strategies strategy NOUN ns064457m3b 12 4 involving involve VERB ns064457m3b 12 5 redox redox ADJ ns064457m3b 12 6 chemistry chemistry NOUN ns064457m3b 12 7 of of ADP ns064457m3b 12 8 both both DET ns064457m3b 12 9 transition transition NOUN ns064457m3b 12 10 metals metal NOUN ns064457m3b 12 11 and and CCONJ ns064457m3b 12 12 phosphorus phosphorus NOUN ns064457m3b 12 13 enable enable VERB ns064457m3b 12 14 a a DET ns064457m3b 12 15 fast fast ADJ ns064457m3b 12 16 and and CCONJ ns064457m3b 12 17 resourceful resourceful ADJ ns064457m3b 12 18 approach approach NOUN ns064457m3b 12 19 towards towards ADP ns064457m3b 12 20 the the DET ns064457m3b 12 21 construction construction NOUN ns064457m3b 12 22 of of ADP ns064457m3b 12 23 valuable valuable ADJ ns064457m3b 12 24 synthetic synthetic ADJ ns064457m3b 12 25 intermediates intermediate NOUN ns064457m3b 12 26 of of ADP ns064457m3b 12 27 saturated saturated ADJ ns064457m3b 12 28 carbonyls carbonyl NOUN ns064457m3b 12 29 , , PUNCT ns064457m3b 12 30 homoallylic homoallylic ADJ ns064457m3b 12 31 alcohols alcohol NOUN ns064457m3b 12 32 , , PUNCT ns064457m3b 12 33 and and CCONJ ns064457m3b 12 34 substituted substituted ADJ ns064457m3b 12 35 amides amide NOUN ns064457m3b 12 36 from from ADP ns064457m3b 12 37 the the DET ns064457m3b 12 38 readily readily ADV ns064457m3b 12 39 accessible accessible ADJ ns064457m3b 12 40 starting start VERB ns064457m3b 12 41 materials material NOUN ns064457m3b 12 42 . . PUNCT