id	sid	tid	token	lemma	pos
nk322b9134k	1	1	bone	bone	NOUN
nk322b9134k	1	2	tissue	tissue	NOUN
nk322b9134k	1	3	exhibits	exhibit	VERB
nk322b9134k	1	4	a	a	DET
nk322b9134k	1	5	unique	unique	ADJ
nk322b9134k	1	6	multiscale	multiscale	ADJ
nk322b9134k	1	7	hierarchical	hierarchical	ADJ
nk322b9134k	1	8	composite	composite	ADJ
nk322b9134k	1	9	structure	structure	NOUN
nk322b9134k	1	10	.	.	PUNCT
nk322b9134k	2	1	the	the	DET
nk322b9134k	2	2	material	material	NOUN
nk322b9134k	2	3	,	,	PUNCT
nk322b9134k	2	4	or	or	CCONJ
nk322b9134k	2	5	extracellular	extracellular	ADJ
nk322b9134k	2	6	matrix	matrix	NOUN
nk322b9134k	2	7	,	,	PUNCT
nk322b9134k	2	8	constituent	constituent	NOUN
nk322b9134k	2	9	phases	phase	NOUN
nk322b9134k	2	10	of	of	ADP
nk322b9134k	2	11	water	water	NOUN
nk322b9134k	2	12	,	,	PUNCT
nk322b9134k	2	13	collagen	collagen	PROPN
nk322b9134k	2	14	,	,	PUNCT
nk322b9134k	2	15	and	and	CCONJ
nk322b9134k	2	16	apatite	apatite	PROPN
nk322b9134k	2	17	bone	bone	NOUN
nk322b9134k	2	18	mineral	mineral	NOUN
nk322b9134k	2	19	are	be	AUX
nk322b9134k	2	20	organized	organize	VERB
nk322b9134k	2	21	and	and	CCONJ
nk322b9134k	2	22	preferentially	preferentially	ADV
nk322b9134k	2	23	oriented	orient	VERB
nk322b9134k	2	24	over	over	ADP
nk322b9134k	2	25	several	several	ADJ
nk322b9134k	2	26	length	length	NOUN
nk322b9134k	2	27	scales	scale	NOUN
nk322b9134k	2	28	to	to	PART
nk322b9134k	2	29	optimally	optimally	ADV
nk322b9134k	2	30	bear	bear	VERB
nk322b9134k	2	31	and	and	CCONJ
nk322b9134k	2	32	distribute	distribute	VERB
nk322b9134k	2	33	mechanical	mechanical	ADJ
nk322b9134k	2	34	loads	load	NOUN
nk322b9134k	2	35	in	in	ADP
nk322b9134k	2	36	the	the	DET
nk322b9134k	2	37	skeleton	skeleton	NOUN
nk322b9134k	2	38	.	.	PUNCT
nk322b9134k	3	1	at	at	ADP
nk322b9134k	3	2	larger	large	ADJ
nk322b9134k	3	3	length	length	NOUN
nk322b9134k	3	4	scales	scale	NOUN
nk322b9134k	3	5	,	,	PUNCT
nk322b9134k	3	6	the	the	DET
nk322b9134k	3	7	architecture	architecture	NOUN
nk322b9134k	3	8	of	of	ADP
nk322b9134k	3	9	bone	bone	NOUN
nk322b9134k	3	10	is	be	AUX
nk322b9134k	3	11	continually	continually	ADV
nk322b9134k	3	12	remodeled	remodel	VERB
nk322b9134k	3	13	through	through	ADP
nk322b9134k	3	14	the	the	DET
nk322b9134k	3	15	creation	creation	NOUN
nk322b9134k	3	16	of	of	ADP
nk322b9134k	3	17	pore	pore	ADJ
nk322b9134k	3	18	space	space	NOUN
nk322b9134k	3	19	and	and	CCONJ
nk322b9134k	3	20	deposition	deposition	NOUN
nk322b9134k	3	21	of	of	ADP
nk322b9134k	3	22	new	new	ADJ
nk322b9134k	3	23	tissue	tissue	NOUN
nk322b9134k	3	24	.	.	PUNCT
nk322b9134k	4	1	however	however	ADV
nk322b9134k	4	2	,	,	PUNCT
nk322b9134k	4	3	aging	aging	NOUN
nk322b9134k	4	4	and	and	CCONJ
nk322b9134k	4	5	metabolic	metabolic	ADJ
nk322b9134k	4	6	bone	bone	NOUN
nk322b9134k	4	7	diseases	disease	NOUN
nk322b9134k	4	8	such	such	ADJ
nk322b9134k	4	9	as	as	ADP
nk322b9134k	4	10	osteoporosis	osteoporosis	NOUN
nk322b9134k	4	11	can	can	AUX
nk322b9134k	4	12	compromise	compromise	VERB
nk322b9134k	4	13	the	the	DET
nk322b9134k	4	14	mechanical	mechanical	ADJ
nk322b9134k	4	15	integrity	integrity	NOUN
nk322b9134k	4	16	of	of	ADP
nk322b9134k	4	17	bone	bone	NOUN
nk322b9134k	4	18	by	by	ADP
nk322b9134k	4	19	altering	alter	VERB
nk322b9134k	4	20	the	the	DET
nk322b9134k	4	21	material	material	NOUN
nk322b9134k	4	22	and/or	and/or	CCONJ
nk322b9134k	4	23	architectural	architectural	ADJ
nk322b9134k	4	24	properties	property	NOUN
nk322b9134k	4	25	of	of	ADP
nk322b9134k	4	26	bone	bone	NOUN
nk322b9134k	4	27	.	.	PUNCT
nk322b9134k	5	1	therefore	therefore	ADV
nk322b9134k	5	2	,	,	PUNCT
nk322b9134k	5	3	decoupling	decouple	VERB
nk322b9134k	5	4	these	these	DET
nk322b9134k	5	5	structure	structure	NOUN
nk322b9134k	5	6	-	-	PUNCT
nk322b9134k	5	7	function	function	NOUN
nk322b9134k	5	8	relationships	relationship	NOUN
nk322b9134k	5	9	in	in	ADP
nk322b9134k	5	10	bone	bone	NOUN
nk322b9134k	5	11	provides	provide	VERB
nk322b9134k	5	12	mechanistic	mechanistic	ADJ
nk322b9134k	5	13	insights	insight	NOUN
nk322b9134k	5	14	and	and	CCONJ
nk322b9134k	5	15	elucidates	elucidate	NOUN
nk322b9134k	5	16	which	which	PRON
nk322b9134k	5	17	are	be	AUX
nk322b9134k	5	18	most	most	ADV
nk322b9134k	5	19	important	important	ADJ
nk322b9134k	5	20	when	when	SCONJ
nk322b9134k	5	21	developing	develop	VERB
nk322b9134k	5	22	pharmacological	pharmacological	ADJ
nk322b9134k	5	23	treatments	treatment	NOUN
nk322b9134k	5	24	for	for	ADP
nk322b9134k	5	25	metabolic	metabolic	ADJ
nk322b9134k	5	26	bone	bone	NOUN
nk322b9134k	6	1	disease.this	disease.this	DET
nk322b9134k	6	2	dissertation	dissertation	NOUN
nk322b9134k	6	3	investigated	investigate	VERB
nk322b9134k	6	4	the	the	DET
nk322b9134k	6	5	relative	relative	ADJ
nk322b9134k	6	6	contributions	contribution	NOUN
nk322b9134k	6	7	of	of	ADP
nk322b9134k	6	8	material	material	NOUN
nk322b9134k	6	9	and	and	CCONJ
nk322b9134k	6	10	architectural	architectural	ADJ
nk322b9134k	6	11	properties	property	NOUN
nk322b9134k	6	12	on	on	ADP
nk322b9134k	6	13	the	the	DET
nk322b9134k	6	14	mechanical	mechanical	ADJ
nk322b9134k	6	15	behavior	behavior	NOUN
nk322b9134k	6	16	of	of	ADP
nk322b9134k	6	17	bone	bone	NOUN
nk322b9134k	6	18	tissue	tissue	NOUN
nk322b9134k	6	19	using	use	VERB
nk322b9134k	6	20	combined	combine	VERB
nk322b9134k	6	21	numerical	numerical	ADJ
nk322b9134k	6	22	and	and	CCONJ
nk322b9134k	6	23	experimental	experimental	ADJ
nk322b9134k	6	24	techniques	technique	NOUN
nk322b9134k	6	25	.	.	PUNCT
nk322b9134k	7	1	a	a	DET
nk322b9134k	7	2	micromechanical	micromechanical	ADJ
nk322b9134k	7	3	model	model	NOUN
nk322b9134k	7	4	and	and	CCONJ
nk322b9134k	7	5	finite	finite	ADJ
nk322b9134k	7	6	element	element	NOUN
nk322b9134k	7	7	analyses	analysis	NOUN
nk322b9134k	7	8	were	be	AUX
nk322b9134k	7	9	used	use	VERB
nk322b9134k	7	10	to	to	PART
nk322b9134k	7	11	decouple	decouple	VERB
nk322b9134k	7	12	the	the	DET
nk322b9134k	7	13	relative	relative	ADJ
nk322b9134k	7	14	influences	influence	NOUN
nk322b9134k	7	15	of	of	ADP
nk322b9134k	7	16	apatite	apatite	NOUN
nk322b9134k	7	17	crystal	crystal	PROPN
nk322b9134k	7	18	orientations	orientation	NOUN
nk322b9134k	7	19	and	and	CCONJ
nk322b9134k	7	20	intracortical	intracortical	ADJ
nk322b9134k	7	21	porosity	porosity	NOUN
nk322b9134k	7	22	(	(	PUNCT
nk322b9134k	7	23	ct.po	ct.po	PROPN
nk322b9134k	7	24	)	)	PUNCT
nk322b9134k	7	25	on	on	ADP
nk322b9134k	7	26	the	the	DET
nk322b9134k	7	27	elastic	elastic	ADJ
nk322b9134k	7	28	anisotropy	anisotropy	NOUN
nk322b9134k	7	29	of	of	ADP
nk322b9134k	7	30	human	human	ADJ
nk322b9134k	7	31	cortical	cortical	ADJ
nk322b9134k	7	32	bone	bone	NOUN
nk322b9134k	7	33	.	.	PUNCT
nk322b9134k	8	1	the	the	DET
nk322b9134k	8	2	dominant	dominant	ADJ
nk322b9134k	8	3	and	and	CCONJ
nk322b9134k	8	4	less	less	ADV
nk322b9134k	8	5	variable	variable	ADJ
nk322b9134k	8	6	transverse	transverse	NOUN
nk322b9134k	8	7	isotropy	isotropy	NOUN
nk322b9134k	8	8	was	be	AUX
nk322b9134k	8	9	governed	govern	VERB
nk322b9134k	8	10	primarily	primarily	ADV
nk322b9134k	8	11	by	by	ADP
nk322b9134k	8	12	material	material	ADJ
nk322b9134k	8	13	-	-	PUNCT
nk322b9134k	8	14	level	level	NOUN
nk322b9134k	8	15	apatite	apatite	NOUN
nk322b9134k	8	16	crystal	crystal	NOUN
nk322b9134k	8	17	orientations	orientation	NOUN
nk322b9134k	8	18	,	,	PUNCT
nk322b9134k	8	19	while	while	SCONJ
nk322b9134k	8	20	the	the	DET
nk322b9134k	8	21	more	more	ADV
nk322b9134k	8	22	subtle	subtle	ADJ
nk322b9134k	8	23	and	and	CCONJ
nk322b9134k	8	24	variable	variable	ADJ
nk322b9134k	8	25	orthotropy	orthotropy	NOUN
nk322b9134k	8	26	was	be	AUX
nk322b9134k	8	27	governed	govern	VERB
nk322b9134k	8	28	primarily	primarily	ADV
nk322b9134k	8	29	by	by	ADP
nk322b9134k	8	30	ct.po	ct.po	PROPN
nk322b9134k	8	31	.	.	PUNCT
nk322b9134k	9	1	micro	micro	VERB
nk322b9134k	9	2	-	-	ADJ
nk322b9134k	9	3	computed	computed	ADJ
nk322b9134k	9	4	tomography	tomography	NOUN
nk322b9134k	9	5	(	(	PUNCT
nk322b9134k	9	6	micro	micro	NOUN
nk322b9134k	9	7	-	-	NOUN
nk322b9134k	9	8	ct	ct	NOUN
nk322b9134k	9	9	)	)	PUNCT
nk322b9134k	9	10	based	base	VERB
nk322b9134k	9	11	finite	finite	NOUN
nk322b9134k	9	12	element	element	NOUN
nk322b9134k	9	13	models	model	NOUN
nk322b9134k	9	14	of	of	ADP
nk322b9134k	9	15	human	human	ADJ
nk322b9134k	9	16	trabecular	trabecular	ADJ
nk322b9134k	9	17	bone	bone	NOUN
nk322b9134k	9	18	specimens	specimen	NOUN
nk322b9134k	9	19	were	be	AUX
nk322b9134k	9	20	used	use	VERB
nk322b9134k	9	21	to	to	PART
nk322b9134k	9	22	investigate	investigate	VERB
nk322b9134k	9	23	the	the	DET
nk322b9134k	9	24	effect	effect	NOUN
nk322b9134k	9	25	of	of	ADP
nk322b9134k	9	26	constitutive	constitutive	ADJ
nk322b9134k	9	27	models	model	NOUN
nk322b9134k	9	28	on	on	ADP
nk322b9134k	9	29	apparent	apparent	ADJ
nk322b9134k	9	30	and	and	CCONJ
nk322b9134k	9	31	tissue	tissue	NOUN
nk322b9134k	9	32	-	-	PUNCT
nk322b9134k	9	33	level	level	NOUN
nk322b9134k	9	34	yielding	yielding	NOUN
nk322b9134k	9	35	.	.	PUNCT
nk322b9134k	10	1	yield	yield	NOUN
nk322b9134k	10	2	strains	strain	NOUN
nk322b9134k	10	3	and	and	CCONJ
nk322b9134k	10	4	yielding	yield	VERB
nk322b9134k	10	5	modalities	modality	NOUN
nk322b9134k	10	6	exhibited	exhibit	VERB
nk322b9134k	10	7	minimal	minimal	ADJ
nk322b9134k	10	8	dependence	dependence	NOUN
nk322b9134k	10	9	on	on	ADP
nk322b9134k	10	10	material	material	ADJ
nk322b9134k	10	11	constitutive	constitutive	ADJ
nk322b9134k	10	12	model	model	NOUN
nk322b9134k	10	13	in	in	ADP
nk322b9134k	10	14	comparison	comparison	NOUN
nk322b9134k	10	15	to	to	ADP
nk322b9134k	10	16	architecture	architecture	NOUN
nk322b9134k	10	17	.	.	PUNCT
nk322b9134k	11	1	novel	novel	ADJ
nk322b9134k	11	2	experimental	experimental	ADJ
nk322b9134k	11	3	methods	method	NOUN
nk322b9134k	11	4	for	for	ADP
nk322b9134k	11	5	sequential	sequential	ADJ
nk322b9134k	11	6	micro	micro	ADJ
nk322b9134k	11	7	-	-	ADJ
nk322b9134k	11	8	ct	ct	ADJ
nk322b9134k	11	9	imaging	imaging	NOUN
nk322b9134k	11	10	and	and	CCONJ
nk322b9134k	11	11	mechanical	mechanical	ADJ
nk322b9134k	11	12	loading	loading	NOUN
nk322b9134k	11	13	were	be	AUX
nk322b9134k	11	14	used	use	VERB
nk322b9134k	11	15	to	to	PART
nk322b9134k	11	16	investigate	investigate	VERB
nk322b9134k	11	17	the	the	DET
nk322b9134k	11	18	relative	relative	ADJ
nk322b9134k	11	19	influence	influence	NOUN
nk322b9134k	11	20	of	of	ADP
nk322b9134k	11	21	ct.po	ct.po	PROPN
nk322b9134k	11	22	and	and	CCONJ
nk322b9134k	11	23	mineralization	mineralization	NOUN
nk322b9134k	11	24	on	on	ADP
nk322b9134k	11	25	damage	damage	NOUN
nk322b9134k	11	26	accumulation	accumulation	NOUN
nk322b9134k	11	27	and	and	CCONJ
nk322b9134k	11	28	fracture	fracture	NOUN
nk322b9134k	11	29	susceptibility	susceptibility	NOUN
nk322b9134k	11	30	in	in	ADP
nk322b9134k	11	31	human	human	ADJ
nk322b9134k	11	32	cortical	cortical	ADJ
nk322b9134k	11	33	bone	bone	NOUN
nk322b9134k	11	34	.	.	PUNCT
nk322b9134k	12	1	fractures	fracture	NOUN
nk322b9134k	12	2	were	be	AUX
nk322b9134k	12	3	shown	show	VERB
nk322b9134k	12	4	to	to	PART
nk322b9134k	12	5	initiate	initiate	VERB
nk322b9134k	12	6	at	at	ADP
nk322b9134k	12	7	fatigue	fatigue	NOUN
nk322b9134k	12	8	microdamage	microdamage	NOUN
nk322b9134k	12	9	that	that	PRON
nk322b9134k	12	10	was	be	AUX
nk322b9134k	12	11	spatially	spatially	ADV
nk322b9134k	12	12	adjacent	adjacent	ADJ
nk322b9134k	12	13	to	to	ADP
nk322b9134k	12	14	elevated	elevated	ADJ
nk322b9134k	12	15	ct.po	ct.po	PROPN
nk322b9134k	12	16	,	,	PUNCT
nk322b9134k	12	17	but	but	CCONJ
nk322b9134k	12	18	not	not	PART
nk322b9134k	12	19	elevated	elevated	ADJ
nk322b9134k	12	20	mineralization	mineralization	NOUN
nk322b9134k	12	21	.	.	PUNCT
nk322b9134k	13	1	finite	finite	NOUN
nk322b9134k	13	2	element	element	NOUN
nk322b9134k	13	3	models	model	NOUN
nk322b9134k	13	4	were	be	AUX
nk322b9134k	13	5	subsequently	subsequently	ADV
nk322b9134k	13	6	used	use	VERB
nk322b9134k	13	7	to	to	PART
nk322b9134k	13	8	examine	examine	VERB
nk322b9134k	13	9	the	the	DET
nk322b9134k	13	10	relative	relative	ADJ
nk322b9134k	13	11	contributions	contribution	NOUN
nk322b9134k	13	12	of	of	ADP
nk322b9134k	13	13	ct.po	ct.po	PROPN
nk322b9134k	13	14	,	,	PUNCT
nk322b9134k	13	15	mineralization	mineralization	NOUN
nk322b9134k	13	16	,	,	PUNCT
nk322b9134k	13	17	and	and	CCONJ
nk322b9134k	13	18	fatigue	fatigue	NOUN
nk322b9134k	13	19	microdamage	microdamage	NOUN
nk322b9134k	13	20	on	on	ADP
nk322b9134k	13	21	the	the	DET
nk322b9134k	13	22	stress	stress	NOUN
nk322b9134k	13	23	concentrations	concentration	NOUN
nk322b9134k	13	24	at	at	ADP
nk322b9134k	13	25	fracture	fracture	NOUN
nk322b9134k	13	26	initiation	initiation	NOUN
nk322b9134k	13	27	sites	site	NOUN
nk322b9134k	13	28	.	.	PUNCT
nk322b9134k	14	1	elevated	elevate	VERB
nk322b9134k	14	2	stresses	stress	NOUN
nk322b9134k	14	3	at	at	ADP
nk322b9134k	14	4	the	the	DET
nk322b9134k	14	5	fracture	fracture	NOUN
nk322b9134k	14	6	initiation	initiation	NOUN
nk322b9134k	14	7	sites	site	NOUN
nk322b9134k	14	8	were	be	AUX
nk322b9134k	14	9	governed	govern	VERB
nk322b9134k	14	10	by	by	ADP
nk322b9134k	14	11	the	the	DET
nk322b9134k	14	12	coupled	couple	VERB
nk322b9134k	14	13	effects	effect	NOUN
nk322b9134k	14	14	of	of	ADP
nk322b9134k	14	15	ct.po	ct.po	PROPN
nk322b9134k	14	16	and	and	CCONJ
nk322b9134k	14	17	fatigue	fatigue	NOUN
nk322b9134k	14	18	microdamage	microdamage	PROPN
nk322b9134k	14	19	,	,	PUNCT
nk322b9134k	14	20	but	but	CCONJ
nk322b9134k	14	21	not	not	PART
nk322b9134k	14	22	mineralization	mineralization	NOUN
nk322b9134k	14	23	.	.	PUNCT
nk322b9134k	15	1	finally	finally	ADV
nk322b9134k	15	2	,	,	PUNCT
nk322b9134k	15	3	in	in	ADP
nk322b9134k	15	4	vivo	vivo	ADJ
nk322b9134k	15	5	rabbit	rabbit	NOUN
nk322b9134k	15	6	ulnar	ulnar	NOUN
nk322b9134k	15	7	loading	loading	NOUN
nk322b9134k	15	8	was	be	AUX
nk322b9134k	15	9	developed	develop	VERB
nk322b9134k	15	10	and	and	CCONJ
nk322b9134k	15	11	validated	validate	VERB
nk322b9134k	15	12	as	as	ADP
nk322b9134k	15	13	a	a	DET
nk322b9134k	15	14	new	new	ADJ
nk322b9134k	15	15	model	model	NOUN
nk322b9134k	15	16	for	for	ADP
nk322b9134k	15	17	preclinical	preclinical	ADJ
nk322b9134k	15	18	investigations	investigation	NOUN
nk322b9134k	15	19	of	of	ADP
nk322b9134k	15	20	bone	bone	NOUN
nk322b9134k	15	21	mechanobiology	mechanobiology	NOUN
nk322b9134k	15	22	which	which	PRON
nk322b9134k	15	23	includes	include	VERB
nk322b9134k	15	24	intracortical	intracortical	ADJ
nk322b9134k	15	25	remodeling	remodeling	NOUN
nk322b9134k	15	26	similar	similar	ADJ
nk322b9134k	15	27	to	to	ADP
nk322b9134k	15	28	human	human	ADJ
nk322b9134k	15	29	bone	bone	NOUN
nk322b9134k	15	30	biology	biology	NOUN
nk322b9134k	15	31	.	.	PUNCT
nk322b9134k	16	1	lamellar	lamellar	ADJ
nk322b9134k	16	2	bone	bone	NOUN
nk322b9134k	16	3	formation	formation	NOUN
nk322b9134k	16	4	in	in	ADP
nk322b9134k	16	5	rabbit	rabbit	NOUN
nk322b9134k	16	6	ulnae	ulnae	NOUN
nk322b9134k	16	7	exhibited	exhibit	VERB
nk322b9134k	16	8	a	a	DET
nk322b9134k	16	9	tightly	tightly	ADV
nk322b9134k	16	10	controlled	control	VERB
nk322b9134k	16	11	dose	dose	NOUN
nk322b9134k	16	12	-	-	PUNCT
nk322b9134k	16	13	dependent	dependent	ADJ
nk322b9134k	16	14	response	response	NOUN
nk322b9134k	16	15	to	to	ADP
nk322b9134k	16	16	strains	strain	NOUN
nk322b9134k	16	17	induced	induce	VERB
nk322b9134k	16	18	by	by	ADP
nk322b9134k	16	19	mechanical	mechanical	ADJ
nk322b9134k	16	20	loading	loading	NOUN
nk322b9134k	16	21	.	.	PUNCT