id sid tid token lemma pos n583xs57z6j 1 1 cytoplasmic cytoplasmic ADJ n583xs57z6j 1 2 dynein dynein NOUN n583xs57z6j 1 3 is be AUX n583xs57z6j 1 4 a a DET n583xs57z6j 1 5 minus minus ADJ n583xs57z6j 1 6 - - PUNCT n583xs57z6j 1 7 end end NOUN n583xs57z6j 1 8 directed direct VERB n583xs57z6j 1 9 microtubule microtubule NOUN n583xs57z6j 1 10 - - PUNCT n583xs57z6j 1 11 based base VERB n583xs57z6j 1 12 motor motor NOUN n583xs57z6j 1 13 protein protein NOUN n583xs57z6j 1 14 that that PRON n583xs57z6j 1 15 is be AUX n583xs57z6j 1 16 responsible responsible ADJ n583xs57z6j 1 17 for for ADP n583xs57z6j 1 18 the the DET n583xs57z6j 1 19 transport transport NOUN n583xs57z6j 1 20 and and CCONJ n583xs57z6j 1 21 positioning positioning NOUN n583xs57z6j 1 22 of of ADP n583xs57z6j 1 23 diverse diverse ADJ n583xs57z6j 1 24 cellular cellular ADJ n583xs57z6j 1 25 structures structure NOUN n583xs57z6j 1 26 within within ADP n583xs57z6j 1 27 eukaryotic eukaryotic ADJ n583xs57z6j 1 28 cells cell NOUN n583xs57z6j 1 29 , , PUNCT n583xs57z6j 1 30 including include VERB n583xs57z6j 1 31 membranous membranous ADJ n583xs57z6j 1 32 organelles organelle NOUN n583xs57z6j 1 33 and and CCONJ n583xs57z6j 1 34 chromosomes chromosome NOUN n583xs57z6j 1 35 during during ADP n583xs57z6j 1 36 mitosis mitosis NOUN n583xs57z6j 1 37 . . PUNCT n583xs57z6j 2 1 previous previous ADJ n583xs57z6j 2 2 work work NOUN n583xs57z6j 2 3 identified identify VERB n583xs57z6j 2 4 a a DET n583xs57z6j 2 5 phosphorylation phosphorylation NOUN n583xs57z6j 2 6 site site NOUN n583xs57z6j 2 7 in in ADP n583xs57z6j 2 8 one one NUM n583xs57z6j 2 9 of of ADP n583xs57z6j 2 10 the the DET n583xs57z6j 2 11 dynein dynein NOUN n583xs57z6j 2 12 subunits subunit NOUN n583xs57z6j 2 13 ( ( PUNCT n583xs57z6j 2 14 intermediate intermediate ADJ n583xs57z6j 2 15 chains chain NOUN n583xs57z6j 2 16 ( ( PUNCT n583xs57z6j 2 17 ics ics X n583xs57z6j 2 18 ) ) PUNCT n583xs57z6j 2 19 , , PUNCT n583xs57z6j 2 20 which which PRON n583xs57z6j 2 21 regulates regulate VERB n583xs57z6j 2 22 binding binding ADJ n583xs57z6j 2 23 to to ADP n583xs57z6j 2 24 the the DET n583xs57z6j 2 25 putative putative ADJ n583xs57z6j 2 26 receptor receptor NOUN n583xs57z6j 2 27 complex complex ADJ n583xs57z6j 2 28 dynactin dynactin NOUN n583xs57z6j 2 29 during during ADP n583xs57z6j 2 30 interphase interphase NOUN n583xs57z6j 2 31 ( ( PUNCT n583xs57z6j 2 32 vaughan vaughan PROPN n583xs57z6j 2 33 et et PROPN n583xs57z6j 2 34 al al PROPN n583xs57z6j 2 35 . . PROPN n583xs57z6j 2 36 , , PUNCT n583xs57z6j 2 37 2001 2001 NUM n583xs57z6j 2 38 ) ) PUNCT n583xs57z6j 2 39 . . PUNCT n583xs57z6j 3 1 to to PART n583xs57z6j 3 2 identify identify VERB n583xs57z6j 3 3 dynein dynein NOUN n583xs57z6j 3 4 kinases kinase NOUN n583xs57z6j 3 5 and and CCONJ n583xs57z6j 3 6 to to PART n583xs57z6j 3 7 further far ADV n583xs57z6j 3 8 investigate investigate VERB n583xs57z6j 3 9 dynein dynein ADJ n583xs57z6j 3 10 cargo cargo NOUN n583xs57z6j 3 11 - - PUNCT n583xs57z6j 3 12 targeting target VERB n583xs57z6j 3 13 mechanisms mechanism NOUN n583xs57z6j 3 14 , , PUNCT n583xs57z6j 3 15 we we PRON n583xs57z6j 3 16 examined examine VERB n583xs57z6j 3 17 mitotic mitotic ADJ n583xs57z6j 3 18 dynein dynein NOUN n583xs57z6j 3 19 and and CCONJ n583xs57z6j 3 20 determined determine VERB n583xs57z6j 3 21 that that SCONJ n583xs57z6j 3 22 the the DET n583xs57z6j 3 23 mitotic mitotic ADJ n583xs57z6j 3 24 ics ic NOUN n583xs57z6j 3 25 are be AUX n583xs57z6j 3 26 phosphorylated phosphorylate VERB n583xs57z6j 3 27 by by ADP n583xs57z6j 3 28 gel gel NOUN n583xs57z6j 3 29 - - PUNCT n583xs57z6j 3 30 shift shift NOUN n583xs57z6j 3 31 and and CCONJ n583xs57z6j 3 32 2d 2d NUM n583xs57z6j 3 33 gel gel NOUN n583xs57z6j 3 34 analysis analysis NOUN n583xs57z6j 3 35 . . PUNCT n583xs57z6j 4 1 ics ics PROPN n583xs57z6j 4 2 were be AUX n583xs57z6j 4 3 subjected subject VERB n583xs57z6j 4 4 to to ADP n583xs57z6j 4 5 ms ms PROPN n583xs57z6j 4 6 / / SYM n583xs57z6j 4 7 ms ms PROPN n583xs57z6j 4 8 analysis analysis NOUN n583xs57z6j 4 9 revealing reveal VERB n583xs57z6j 4 10 two two NUM n583xs57z6j 4 11 novel novel ADJ n583xs57z6j 4 12 phosphorylation phosphorylation NOUN n583xs57z6j 4 13 sites site NOUN n583xs57z6j 4 14 . . PUNCT n583xs57z6j 5 1 t89 t89 NOUN n583xs57z6j 5 2 falls fall VERB n583xs57z6j 5 3 within within ADP n583xs57z6j 5 4 the the DET n583xs57z6j 5 5 binding bind VERB n583xs57z6j 5 6 domain domain NOUN n583xs57z6j 5 7 for for ADP n583xs57z6j 5 8 dynactin dynactin NOUN n583xs57z6j 5 9 , , PUNCT n583xs57z6j 5 10 and and CCONJ n583xs57z6j 5 11 site site NOUN n583xs57z6j 5 12 - - PUNCT n583xs57z6j 5 13 directed direct VERB n583xs57z6j 5 14 mutants mutant NOUN n583xs57z6j 5 15 designed design VERB n583xs57z6j 5 16 to to PART n583xs57z6j 5 17 mimic mimic VERB n583xs57z6j 5 18 a a DET n583xs57z6j 5 19 phosphorylated phosphorylated ADJ n583xs57z6j 5 20 state state NOUN n583xs57z6j 5 21 reduce reduce VERB n583xs57z6j 5 22 dynactin dynactin NOUN n583xs57z6j 5 23 binding bind VERB n583xs57z6j 5 24 significantly significantly ADV n583xs57z6j 5 25 . . PUNCT n583xs57z6j 6 1 t89 t89 NOUN n583xs57z6j 6 2 fits fit VERB n583xs57z6j 6 3 the the DET n583xs57z6j 6 4 consensus consensus NOUN n583xs57z6j 6 5 for for ADP n583xs57z6j 6 6 p38mapk p38mapk PROPN n583xs57z6j 6 7 , , PUNCT n583xs57z6j 6 8 and and CCONJ n583xs57z6j 6 9 phosphorylation phosphorylation NOUN n583xs57z6j 6 10 by by ADP n583xs57z6j 6 11 p38mapk p38mapk PROPN n583xs57z6j 6 12 is be AUX n583xs57z6j 6 13 specific specific ADJ n583xs57z6j 6 14 for for ADP n583xs57z6j 6 15 this this DET n583xs57z6j 6 16 site site NOUN n583xs57z6j 6 17 in in ADP n583xs57z6j 6 18 vitro vitro X n583xs57z6j 6 19 . . PUNCT n583xs57z6j 7 1 both both CCONJ n583xs57z6j 7 2 dynein dynein PROPN n583xs57z6j 7 3 and and CCONJ n583xs57z6j 7 4 p38 p38 PROPN n583xs57z6j 7 5 have have AUX n583xs57z6j 7 6 been be AUX n583xs57z6j 7 7 independently independently ADV n583xs57z6j 7 8 implicated implicate VERB n583xs57z6j 7 9 in in ADP n583xs57z6j 7 10 kinetochore kinetochore PROPN n583xs57z6j 7 11 checkpoint checkpoint NOUN n583xs57z6j 7 12 roles role NOUN n583xs57z6j 7 13 during during ADP n583xs57z6j 7 14 the the DET n583xs57z6j 7 15 spindle spindle NOUN n583xs57z6j 7 16 assembly assembly NOUN n583xs57z6j 7 17 checkpoint checkpoint NOUN n583xs57z6j 7 18 . . PUNCT n583xs57z6j 8 1 inhibition inhibition NOUN n583xs57z6j 8 2 of of ADP n583xs57z6j 8 3 p38mapk p38mapk PROPN n583xs57z6j 8 4 results result NOUN n583xs57z6j 8 5 in in ADP n583xs57z6j 8 6 redistribution redistribution NOUN n583xs57z6j 8 7 of of ADP n583xs57z6j 8 8 dynein dynein NOUN n583xs57z6j 8 9 from from ADP n583xs57z6j 8 10 kinetochores kinetochore NOUN n583xs57z6j 8 11 to to ADP n583xs57z6j 8 12 spindle spindle NOUN n583xs57z6j 8 13 poles pole NOUN n583xs57z6j 8 14 and and CCONJ n583xs57z6j 8 15 induces induce VERB n583xs57z6j 8 16 dispersed disperse VERB n583xs57z6j 8 17 lagging lag VERB n583xs57z6j 8 18 chromosomes chromosome NOUN n583xs57z6j 8 19 . . PUNCT n583xs57z6j 9 1 phospho phospho NOUN n583xs57z6j 9 2 - - PUNCT n583xs57z6j 9 3 specific specific ADJ n583xs57z6j 9 4 antibodies antibody NOUN n583xs57z6j 9 5 reveal reveal VERB n583xs57z6j 9 6 that that SCONJ n583xs57z6j 9 7 ics ic NOUN n583xs57z6j 9 8 phosphorylated phosphorylate VERB n583xs57z6j 9 9 at at ADP n583xs57z6j 9 10 t89 t89 NOUN n583xs57z6j 9 11 bind bind VERB n583xs57z6j 9 12 to to ADP n583xs57z6j 9 13 pro pro ADJ n583xs57z6j 9 14 - - ADJ n583xs57z6j 9 15 metaphase metaphase ADJ n583xs57z6j 9 16 kinetochores kinetochore NOUN n583xs57z6j 9 17 and and CCONJ n583xs57z6j 9 18 are be AUX n583xs57z6j 9 19 absent absent ADJ n583xs57z6j 9 20 from from ADP n583xs57z6j 9 21 kinetochores kinetochore NOUN n583xs57z6j 9 22 that that PRON n583xs57z6j 9 23 have have AUX n583xs57z6j 9 24 achieved achieve VERB n583xs57z6j 9 25 microtubule microtubule NOUN n583xs57z6j 9 26 attachment attachment NOUN n583xs57z6j 9 27 and and CCONJ n583xs57z6j 9 28 chromosome chromosome NOUN n583xs57z6j 9 29 alignment alignment NOUN n583xs57z6j 9 30 on on ADP n583xs57z6j 9 31 the the DET n583xs57z6j 9 32 metaphase metaphase NOUN n583xs57z6j 9 33 plate plate NOUN n583xs57z6j 9 34 . . PUNCT n583xs57z6j 10 1 in in ADP n583xs57z6j 10 2 contrast contrast NOUN n583xs57z6j 10 3 , , PUNCT n583xs57z6j 10 4 ics ic NOUN n583xs57z6j 10 5 phosphorylated phosphorylate VERB n583xs57z6j 10 6 at at ADP n583xs57z6j 10 7 y130 y130 PROPN n583xs57z6j 10 8 localize localize VERB n583xs57z6j 10 9 to to ADP n583xs57z6j 10 10 mitotic mitotic ADJ n583xs57z6j 10 11 spindle spindle NOUN n583xs57z6j 10 12 poles pole NOUN n583xs57z6j 10 13 and and CCONJ n583xs57z6j 10 14 reside reside VERB n583xs57z6j 10 15 there there ADV n583xs57z6j 10 16 from from ADP n583xs57z6j 10 17 early early ADJ n583xs57z6j 10 18 prophase prophase NOUN n583xs57z6j 10 19 until until ADP n583xs57z6j 10 20 late late ADJ n583xs57z6j 10 21 anaphase anaphase NOUN n583xs57z6j 10 22 . . PUNCT n583xs57z6j 11 1 y130 y130 PROPN n583xs57z6j 11 2 falls fall VERB n583xs57z6j 11 3 within within ADP n583xs57z6j 11 4 a a DET n583xs57z6j 11 5 domain domain NOUN n583xs57z6j 11 6 implicated implicate VERB n583xs57z6j 11 7 in in ADP n583xs57z6j 11 8 lc8 lc8 PROPN n583xs57z6j 11 9 ( ( PUNCT n583xs57z6j 11 10 a a DET n583xs57z6j 11 11 dynein dynein NOUN n583xs57z6j 11 12 light light NOUN n583xs57z6j 11 13 chain chain NOUN n583xs57z6j 11 14 ) ) PUNCT n583xs57z6j 11 15 binding bind VERB n583xs57z6j 11 16 and and CCONJ n583xs57z6j 11 17 fits fit VERB n583xs57z6j 11 18 the the DET n583xs57z6j 11 19 consensus consensus NOUN n583xs57z6j 11 20 for for ADP n583xs57z6j 11 21 phosphorylation phosphorylation NOUN n583xs57z6j 11 22 by by ADP n583xs57z6j 11 23 c c PROPN n583xs57z6j 11 24 - - PUNCT n583xs57z6j 11 25 abl abl PROPN n583xs57z6j 11 26 kinase kinase NOUN n583xs57z6j 11 27 . . PUNCT n583xs57z6j 12 1 c c X n583xs57z6j 12 2 - - PUNCT n583xs57z6j 12 3 abl abl ADJ n583xs57z6j 12 4 phosphorylates phosphorylate NOUN n583xs57z6j 12 5 wild wild ADJ n583xs57z6j 12 6 - - PUNCT n583xs57z6j 12 7 type type NOUN n583xs57z6j 12 8 , , PUNCT n583xs57z6j 12 9 but but CCONJ n583xs57z6j 12 10 not not PART n583xs57z6j 12 11 y130f y130f ADV n583xs57z6j 12 12 mutant mutant ADJ n583xs57z6j 12 13 ics ics PROPN n583xs57z6j 12 14 in in ADP n583xs57z6j 12 15 vitro vitro X n583xs57z6j 12 16 . . PUNCT n583xs57z6j 13 1 this this DET n583xs57z6j 13 2 phosphorylation phosphorylation NOUN n583xs57z6j 13 3 was be AUX n583xs57z6j 13 4 blocked block VERB n583xs57z6j 13 5 by by ADP n583xs57z6j 13 6 treatment treatment NOUN n583xs57z6j 13 7 with with ADP n583xs57z6j 13 8 gleevec gleevec PROPN n583xs57z6j 13 9 ( ( PUNCT n583xs57z6j 13 10 a a DET n583xs57z6j 13 11 c c NOUN n583xs57z6j 13 12 - - PUNCT n583xs57z6j 13 13 abl abl NOUN n583xs57z6j 13 14 inhibitor inhibitor NOUN n583xs57z6j 13 15 ) ) PUNCT n583xs57z6j 13 16 and and CCONJ n583xs57z6j 13 17 gleevec gleevec PROPN n583xs57z6j 13 18 treatment treatment NOUN n583xs57z6j 13 19 of of ADP n583xs57z6j 13 20 live live ADJ n583xs57z6j 13 21 cells cell NOUN n583xs57z6j 13 22 also also ADV n583xs57z6j 13 23 blocked block VERB n583xs57z6j 13 24 phosphorylation phosphorylation NOUN n583xs57z6j 13 25 at at ADP n583xs57z6j 13 26 y130 y130 PROPN n583xs57z6j 13 27 , , PUNCT n583xs57z6j 13 28 suggesting suggest VERB n583xs57z6j 13 29 that that SCONJ n583xs57z6j 13 30 c c PROPN n583xs57z6j 13 31 - - PUNCT n583xs57z6j 13 32 abl abl NOUN n583xs57z6j 13 33 is be AUX n583xs57z6j 13 34 a a DET n583xs57z6j 13 35 mitotic mitotic ADJ n583xs57z6j 13 36 dynein dynein NOUN n583xs57z6j 13 37 kinase kinase NOUN n583xs57z6j 13 38 . . PUNCT n583xs57z6j 14 1 binding bind VERB n583xs57z6j 14 2 assays assay NOUN n583xs57z6j 14 3 to to PART n583xs57z6j 14 4 test test VERB n583xs57z6j 14 5 the the DET n583xs57z6j 14 6 impact impact NOUN n583xs57z6j 14 7 of of ADP n583xs57z6j 14 8 y130 y130 PROPN n583xs57z6j 14 9 phosphorylation phosphorylation NOUN n583xs57z6j 14 10 demonstrated demonstrate VERB n583xs57z6j 14 11 that that SCONJ n583xs57z6j 14 12 ics ic NOUN n583xs57z6j 14 13 phosphorylated phosphorylate VERB n583xs57z6j 14 14 at at ADP n583xs57z6j 14 15 y130 y130 PROPN n583xs57z6j 14 16 do do AUX n583xs57z6j 14 17 not not PART n583xs57z6j 14 18 bind bind VERB n583xs57z6j 14 19 lc8 lc8 PROPN n583xs57z6j 14 20 . . PUNCT n583xs57z6j 15 1 these these DET n583xs57z6j 15 2 results result NOUN n583xs57z6j 15 3 suggest suggest VERB n583xs57z6j 15 4 that that SCONJ n583xs57z6j 15 5 phosphorylation phosphorylation NOUN n583xs57z6j 15 6 of of ADP n583xs57z6j 15 7 dynein dynein NOUN n583xs57z6j 15 8 ics ics NOUN n583xs57z6j 15 9 modulates modulate NOUN n583xs57z6j 15 10 subunit subunit NOUN n583xs57z6j 15 11 composition composition NOUN n583xs57z6j 15 12 during during ADP n583xs57z6j 15 13 mitosis mitosis NOUN n583xs57z6j 15 14 and and CCONJ n583xs57z6j 15 15 plays play VERB n583xs57z6j 15 16 a a DET n583xs57z6j 15 17 role role NOUN n583xs57z6j 15 18 targeting target VERB n583xs57z6j 15 19 dynein dynein ADJ n583xs57z6j 15 20 ics ic NOUN n583xs57z6j 15 21 to to ADP n583xs57z6j 15 22 specific specific ADJ n583xs57z6j 15 23 functional functional ADJ n583xs57z6j 15 24 mitotic mitotic ADJ n583xs57z6j 15 25 sites site NOUN n583xs57z6j 15 26 . . PUNCT