id sid tid token lemma pos kw52j675b52 1 1 in in ADP kw52j675b52 1 2 this this DET kw52j675b52 1 3 dissertation dissertation NOUN kw52j675b52 1 4 , , PUNCT kw52j675b52 1 5 i i PRON kw52j675b52 1 6 describe describe VERB kw52j675b52 1 7 the the DET kw52j675b52 1 8 results result NOUN kw52j675b52 1 9 of of ADP kw52j675b52 1 10 investigations investigation NOUN kw52j675b52 1 11 into into ADP kw52j675b52 1 12 the the DET kw52j675b52 1 13 influence influence NOUN kw52j675b52 1 14 of of ADP kw52j675b52 1 15 translation translation NOUN kw52j675b52 1 16 on on ADP kw52j675b52 1 17 protein protein NOUN kw52j675b52 1 18 folding fold VERB kw52j675b52 1 19 in in ADP kw52j675b52 1 20 living live VERB kw52j675b52 1 21 cells cell NOUN kw52j675b52 1 22 . . PUNCT kw52j675b52 2 1 the the DET kw52j675b52 2 2 environment environment NOUN kw52j675b52 2 3 in in ADP kw52j675b52 2 4 the the DET kw52j675b52 2 5 cell cell NOUN kw52j675b52 2 6 differs differ VERB kw52j675b52 2 7 greatly greatly ADV kw52j675b52 2 8 from from ADP kw52j675b52 2 9 that that PRON kw52j675b52 2 10 found find VERB kw52j675b52 2 11 in in ADP kw52j675b52 2 12 traditional traditional ADJ kw52j675b52 2 13 experimental experimental ADJ kw52j675b52 2 14 conditions condition NOUN kw52j675b52 2 15 for for ADP kw52j675b52 2 16 measuring measure VERB kw52j675b52 2 17 protein protein NOUN kw52j675b52 2 18 folding fold VERB kw52j675b52 2 19 in in ADP kw52j675b52 2 20 vitro vitro X kw52j675b52 2 21 . . PUNCT kw52j675b52 3 1 in in ADP kw52j675b52 3 2 the the DET kw52j675b52 3 3 cell cell NOUN kw52j675b52 3 4 , , PUNCT kw52j675b52 3 5 protein protein NOUN kw52j675b52 3 6 folding folding NOUN kw52j675b52 3 7 is be AUX kw52j675b52 3 8 coupled couple VERB kw52j675b52 3 9 to to ADP kw52j675b52 3 10 synthesis synthesis NOUN kw52j675b52 3 11 of of ADP kw52j675b52 3 12 the the DET kw52j675b52 3 13 protein protein NOUN kw52j675b52 3 14 by by ADP kw52j675b52 3 15 the the DET kw52j675b52 3 16 ribosome ribosome NOUN kw52j675b52 3 17 . . PUNCT kw52j675b52 4 1 the the DET kw52j675b52 4 2 nascent nascent ADJ kw52j675b52 4 3 polypeptide polypeptide NOUN kw52j675b52 4 4 chain chain NOUN kw52j675b52 4 5 begins begin VERB kw52j675b52 4 6 to to PART kw52j675b52 4 7 fold fold VERB kw52j675b52 4 8 as as SCONJ kw52j675b52 4 9 it it PRON kw52j675b52 4 10 emerges emerge VERB kw52j675b52 4 11 from from ADP kw52j675b52 4 12 the the DET kw52j675b52 4 13 exit exit NOUN kw52j675b52 4 14 tunnel tunnel NOUN kw52j675b52 4 15 of of ADP kw52j675b52 4 16 the the DET kw52j675b52 4 17 ribosome ribosome NOUN kw52j675b52 4 18 . . PUNCT kw52j675b52 5 1 this this DET kw52j675b52 5 2 co co ADJ kw52j675b52 5 3 - - ADJ kw52j675b52 5 4 translational translational ADJ kw52j675b52 5 5 folding folding NOUN kw52j675b52 5 6 represents represent VERB kw52j675b52 5 7 an an DET kw52j675b52 5 8 important important ADJ kw52j675b52 5 9 restriction restriction NOUN kw52j675b52 5 10 on on ADP kw52j675b52 5 11 the the DET kw52j675b52 5 12 conformational conformational ADJ kw52j675b52 5 13 ensemble ensemble NOUN kw52j675b52 5 14 populated populate VERB kw52j675b52 5 15 by by ADP kw52j675b52 5 16 nascent nascent ADJ kw52j675b52 5 17 proteins protein NOUN kw52j675b52 5 18 in in ADP kw52j675b52 5 19 vivo vivo PROPN kw52j675b52 5 20 . . PUNCT kw52j675b52 6 1 in in ADP kw52j675b52 6 2 this this DET kw52j675b52 6 3 thesis thesis NOUN kw52j675b52 6 4 three three NUM kw52j675b52 6 5 sets set NOUN kw52j675b52 6 6 of of ADP kw52j675b52 6 7 investigations investigation NOUN kw52j675b52 6 8 into into ADP kw52j675b52 6 9 the the DET kw52j675b52 6 10 relationship relationship NOUN kw52j675b52 6 11 between between ADP kw52j675b52 6 12 translation translation NOUN kw52j675b52 6 13 and and CCONJ kw52j675b52 6 14 protein protein NOUN kw52j675b52 6 15 folding folding NOUN kw52j675b52 6 16 are be AUX kw52j675b52 6 17 described describe VERB kw52j675b52 6 18 . . PUNCT kw52j675b52 7 1 the the DET kw52j675b52 7 2 first first ADJ kw52j675b52 7 3 investigation investigation NOUN kw52j675b52 7 4 reveals reveal VERB kw52j675b52 7 5 that that SCONJ kw52j675b52 7 6 a a DET kw52j675b52 7 7 protein protein NOUN kw52j675b52 7 8 populates populate VERB kw52j675b52 7 9 different different ADJ kw52j675b52 7 10 conformations conformation NOUN kw52j675b52 7 11 after after ADP kw52j675b52 7 12 folding fold VERB kw52j675b52 7 13 co co NOUN kw52j675b52 7 14 - - NOUN kw52j675b52 7 15 translationally translationally ADV kw52j675b52 7 16 than than SCONJ kw52j675b52 7 17 it it PRON kw52j675b52 7 18 does do AUX kw52j675b52 7 19 in in ADP kw52j675b52 7 20 a a DET kw52j675b52 7 21 variety variety NOUN kw52j675b52 7 22 of of ADP kw52j675b52 7 23 in in ADP kw52j675b52 7 24 vitro vitro X kw52j675b52 7 25 refolding refolding NOUN kw52j675b52 7 26 conditions condition NOUN kw52j675b52 7 27 . . PUNCT kw52j675b52 8 1 the the DET kw52j675b52 8 2 next next ADJ kw52j675b52 8 3 investigation investigation NOUN kw52j675b52 8 4 shows show VERB kw52j675b52 8 5 that that SCONJ kw52j675b52 8 6 small small ADJ kw52j675b52 8 7 , , PUNCT kw52j675b52 8 8 genetically genetically ADV kw52j675b52 8 9 encoded encode VERB kw52j675b52 8 10 changes change NOUN kw52j675b52 8 11 in in ADP kw52j675b52 8 12 translation translation NOUN kw52j675b52 8 13 rate rate NOUN kw52j675b52 8 14 can can AUX kw52j675b52 8 15 predictably predictably ADV kw52j675b52 8 16 alter alter VERB kw52j675b52 8 17 the the DET kw52j675b52 8 18 folded fold VERB kw52j675b52 8 19 state state NOUN kw52j675b52 8 20 of of ADP kw52j675b52 8 21 a a DET kw52j675b52 8 22 protein protein NOUN kw52j675b52 8 23 . . PUNCT kw52j675b52 9 1 this this DET kw52j675b52 9 2 thesis thesis NOUN kw52j675b52 9 3 shows show VERB kw52j675b52 9 4 for for ADP kw52j675b52 9 5 the the DET kw52j675b52 9 6 first first ADJ kw52j675b52 9 7 time time NOUN kw52j675b52 9 8 that that SCONJ kw52j675b52 9 9 the the DET kw52j675b52 9 10 co co ADJ kw52j675b52 9 11 - - ADJ kw52j675b52 9 12 translational translational ADJ kw52j675b52 9 13 molecular molecular ADJ kw52j675b52 9 14 chaperone chaperone NOUN kw52j675b52 9 15 trigger trigger NOUN kw52j675b52 9 16 factor factor NOUN kw52j675b52 9 17 can can AUX kw52j675b52 9 18 promote promote VERB kw52j675b52 9 19 the the DET kw52j675b52 9 20 formation formation NOUN kw52j675b52 9 21 of of ADP kw52j675b52 9 22 native native ADJ kw52j675b52 9 23 folded fold VERB kw52j675b52 9 24 structure structure NOUN kw52j675b52 9 25 by by ADP kw52j675b52 9 26 nascent nascent ADJ kw52j675b52 9 27 polypeptides polypeptide NOUN kw52j675b52 9 28 still still ADV kw52j675b52 9 29 associated associate VERB kw52j675b52 9 30 with with ADP kw52j675b52 9 31 the the DET kw52j675b52 9 32 ribosome ribosome NOUN kw52j675b52 9 33 . . PUNCT kw52j675b52 10 1 investigations investigation NOUN kw52j675b52 10 2 into into ADP kw52j675b52 10 3 the the DET kw52j675b52 10 4 role role NOUN kw52j675b52 10 5 of of ADP kw52j675b52 10 6 genetic genetic ADJ kw52j675b52 10 7 elements element NOUN kw52j675b52 10 8 that that PRON kw52j675b52 10 9 modulate modulate VERB kw52j675b52 10 10 translation translation NOUN kw52j675b52 10 11 on on ADP kw52j675b52 10 12 bacterial bacterial ADJ kw52j675b52 10 13 physiology physiology NOUN kw52j675b52 10 14 are be AUX kw52j675b52 10 15 also also ADV kw52j675b52 10 16 described describe VERB kw52j675b52 10 17 . . PUNCT kw52j675b52 11 1 the the DET kw52j675b52 11 2 results result NOUN kw52j675b52 11 3 presented present VERB kw52j675b52 11 4 in in ADP kw52j675b52 11 5 this this DET kw52j675b52 11 6 thesis thesis NOUN kw52j675b52 11 7 show show VERB kw52j675b52 11 8 that that SCONJ kw52j675b52 11 9 the the DET kw52j675b52 11 10 coupling coupling NOUN kw52j675b52 11 11 of of ADP kw52j675b52 11 12 protein protein NOUN kw52j675b52 11 13 folding fold VERB kw52j675b52 11 14 to to ADP kw52j675b52 11 15 the the DET kw52j675b52 11 16 process process NOUN kw52j675b52 11 17 of of ADP kw52j675b52 11 18 translation translation NOUN kw52j675b52 11 19 is be AUX kw52j675b52 11 20 critical critical ADJ kw52j675b52 11 21 part part NOUN kw52j675b52 11 22 of of ADP kw52j675b52 11 23 how how SCONJ kw52j675b52 11 24 nascent nascent ADJ kw52j675b52 11 25 proteins protein NOUN kw52j675b52 11 26 reach reach VERB kw52j675b52 11 27 their their PRON kw52j675b52 11 28 native native ADJ kw52j675b52 11 29 structures structure NOUN kw52j675b52 11 30 in in ADP kw52j675b52 11 31 vivo vivo PROPN kw52j675b52 11 32 . . PUNCT