id	sid	tid	token	lemma	pos
kw52j67591c	1	1	the	the	DET
kw52j67591c	1	2	mosquito	mosquito	PROPN
kw52j67591c	1	3	-	-	PUNCT
kw52j67591c	1	4	vectored	vectore	VERB
kw52j67591c	1	5	dengue	dengue	NOUN
kw52j67591c	1	6	virus	virus	NOUN
kw52j67591c	1	7	(	(	PUNCT
kw52j67591c	1	8	denv	denv	NOUN
kw52j67591c	1	9	)	)	PUNCT
kw52j67591c	1	10	causes	cause	VERB
kw52j67591c	1	11	a	a	DET
kw52j67591c	1	12	potentially	potentially	ADV
kw52j67591c	1	13	fatal	fatal	ADJ
kw52j67591c	1	14	infection	infection	NOUN
kw52j67591c	1	15	found	find	VERB
kw52j67591c	1	16	mostly	mostly	ADV
kw52j67591c	1	17	in	in	ADP
kw52j67591c	1	18	tropical	tropical	ADJ
kw52j67591c	1	19	regions	region	NOUN
kw52j67591c	1	20	of	of	ADP
kw52j67591c	1	21	the	the	DET
kw52j67591c	1	22	world	world	NOUN
kw52j67591c	1	23	.	.	PUNCT
kw52j67591c	2	1	nearly	nearly	ADV
kw52j67591c	2	2	2.5	2.5	NUM
kw52j67591c	2	3	billion	billion	NUM
kw52j67591c	2	4	people	people	NOUN
kw52j67591c	2	5	are	be	AUX
kw52j67591c	2	6	at	at	ADP
kw52j67591c	2	7	risk	risk	NOUN
kw52j67591c	2	8	of	of	ADP
kw52j67591c	2	9	infection	infection	NOUN
kw52j67591c	2	10	and	and	CCONJ
kw52j67591c	2	11	an	an	DET
kw52j67591c	2	12	estimated	estimate	VERB
kw52j67591c	2	13	50	50	NUM
kw52j67591c	2	14	million	million	NUM
kw52j67591c	2	15	cases	case	NOUN
kw52j67591c	2	16	occur	occur	VERB
kw52j67591c	2	17	annually	annually	ADV
kw52j67591c	2	18	.	.	PUNCT
kw52j67591c	3	1	there	there	PRON
kw52j67591c	3	2	is	be	VERB
kw52j67591c	3	3	no	no	DET
kw52j67591c	3	4	vaccine	vaccine	NOUN
kw52j67591c	3	5	and	and	CCONJ
kw52j67591c	3	6	the	the	DET
kw52j67591c	3	7	only	only	ADJ
kw52j67591c	3	8	way	way	NOUN
kw52j67591c	3	9	to	to	PART
kw52j67591c	3	10	fight	fight	VERB
kw52j67591c	3	11	the	the	DET
kw52j67591c	3	12	spread	spread	NOUN
kw52j67591c	3	13	of	of	ADP
kw52j67591c	3	14	dengue	dengue	NOUN
kw52j67591c	3	15	is	be	AUX
kw52j67591c	3	16	to	to	PART
kw52j67591c	3	17	combat	combat	VERB
kw52j67591c	3	18	the	the	DET
kw52j67591c	3	19	mosquito	mosquito	PROPN
kw52j67591c	3	20	vector	vector	NOUN
kw52j67591c	3	21	.	.	PUNCT
kw52j67591c	4	1	an	an	DET
kw52j67591c	4	2	emerging	emerge	VERB
kw52j67591c	4	3	strategy	strategy	NOUN
kw52j67591c	4	4	for	for	ADP
kw52j67591c	4	5	preventing	prevent	VERB
kw52j67591c	4	6	dengue	dengue	NOUN
kw52j67591c	4	7	transmission	transmission	NOUN
kw52j67591c	4	8	involves	involve	VERB
kw52j67591c	4	9	genetic	genetic	ADJ
kw52j67591c	4	10	modification	modification	NOUN
kw52j67591c	4	11	of	of	ADP
kw52j67591c	4	12	the	the	DET
kw52j67591c	4	13	mosquito	mosquito	NOUN
kw52j67591c	4	14	with	with	ADP
kw52j67591c	4	15	anti	anti	ADJ
kw52j67591c	4	16	-	-	ADJ
kw52j67591c	4	17	viral	viral	ADJ
kw52j67591c	4	18	agents	agent	NOUN
kw52j67591c	4	19	.	.	PUNCT
kw52j67591c	5	1	rna	rna	NOUN
kw52j67591c	5	2	enzymes	enzyme	NOUN
kw52j67591c	5	3	known	know	VERB
kw52j67591c	5	4	as	as	ADP
kw52j67591c	5	5	ribozymes	ribozyme	NOUN
kw52j67591c	5	6	hold	hold	VERB
kw52j67591c	5	7	great	great	ADJ
kw52j67591c	5	8	potential	potential	NOUN
kw52j67591c	5	9	in	in	ADP
kw52j67591c	5	10	this	this	DET
kw52j67591c	5	11	area	area	NOUN
kw52j67591c	5	12	due	due	ADP
kw52j67591c	5	13	to	to	ADP
kw52j67591c	5	14	their	their	PRON
kw52j67591c	5	15	autocatalytic	autocatalytic	ADJ
kw52j67591c	5	16	properties	property	NOUN
kw52j67591c	5	17	and	and	CCONJ
kw52j67591c	5	18	minimal	minimal	ADJ
kw52j67591c	5	19	cofactor	cofactor	NOUN
kw52j67591c	5	20	requirements	requirement	NOUN
kw52j67591c	5	21	.	.	PUNCT
kw52j67591c	6	1	the	the	DET
kw52j67591c	6	2	hepatitis	hepatitis	PROPN
kw52j67591c	6	3	delta	delta	PROPN
kw52j67591c	6	4	virus	virus	NOUN
kw52j67591c	6	5	(	(	PUNCT
kw52j67591c	6	6	hdv	hdv	PROPN
kw52j67591c	6	7	)	)	PUNCT
kw52j67591c	6	8	ribozyme	ribozyme	NOUN
kw52j67591c	6	9	is	be	AUX
kw52j67591c	6	10	a	a	DET
kw52j67591c	6	11	promising	promising	ADJ
kw52j67591c	6	12	candidate	candidate	NOUN
kw52j67591c	6	13	for	for	ADP
kw52j67591c	6	14	dengue	dengue	NOUN
kw52j67591c	6	15	inactivation	inactivation	NOUN
kw52j67591c	6	16	because	because	SCONJ
kw52j67591c	6	17	it	it	PRON
kw52j67591c	6	18	can	can	AUX
kw52j67591c	6	19	be	be	AUX
kw52j67591c	6	20	easily	easily	ADV
kw52j67591c	6	21	altered	alter	VERB
kw52j67591c	6	22	to	to	PART
kw52j67591c	6	23	cleave	cleave	VERB
kw52j67591c	6	24	a	a	DET
kw52j67591c	6	25	target	target	NOUN
kw52j67591c	6	26	of	of	ADP
kw52j67591c	6	27	choice	choice	NOUN
kw52j67591c	6	28	and	and	CCONJ
kw52j67591c	6	29	is	be	AUX
kw52j67591c	6	30	both	both	PRON
kw52j67591c	6	31	active	active	ADJ
kw52j67591c	6	32	and	and	CCONJ
kw52j67591c	6	33	stable	stable	ADJ
kw52j67591c	6	34	at	at	ADP
kw52j67591c	6	35	physiological	physiological	ADJ
kw52j67591c	6	36	ph	ph	NOUN
kw52j67591c	6	37	and	and	CCONJ
kw52j67591c	6	38	magnesium	magnesium	NOUN
kw52j67591c	6	39	concentrations	concentration	NOUN
kw52j67591c	6	40	.	.	PUNCT
kw52j67591c	7	1	we	we	PRON
kw52j67591c	7	2	have	have	AUX
kw52j67591c	7	3	investigated	investigate	VERB
kw52j67591c	7	4	the	the	DET
kw52j67591c	7	5	potential	potential	NOUN
kw52j67591c	7	6	of	of	ADP
kw52j67591c	7	7	an	an	DET
kw52j67591c	7	8	hdv	hdv	NOUN
kw52j67591c	7	9	-	-	PUNCT
kw52j67591c	7	10	based	base	VERB
kw52j67591c	7	11	ribozyme	ribozyme	NOUN
kw52j67591c	7	12	to	to	PART
kw52j67591c	7	13	function	function	VERB
kw52j67591c	7	14	as	as	ADP
kw52j67591c	7	15	a	a	DET
kw52j67591c	7	16	means	means	NOUN
kw52j67591c	7	17	of	of	ADP
kw52j67591c	7	18	inducing	induce	VERB
kw52j67591c	7	19	denv	denv	ADJ
kw52j67591c	7	20	refractivity	refractivity	NOUN
kw52j67591c	7	21	in	in	ADP
kw52j67591c	7	22	mosquitoes	mosquito	NOUN
kw52j67591c	7	23	.	.	PUNCT
kw52j67591c	8	1	we	we	PRON
kw52j67591c	8	2	have	have	AUX
kw52j67591c	8	3	modified	modify	VERB
kw52j67591c	8	4	the	the	DET
kw52j67591c	8	5	hdv	hdv	NOUN
kw52j67591c	8	6	ribozyme	ribozyme	NOUN
kw52j67591c	8	7	to	to	PART
kw52j67591c	8	8	target	target	VERB
kw52j67591c	8	9	a	a	DET
kw52j67591c	8	10	portion	portion	NOUN
kw52j67591c	8	11	of	of	ADP
kw52j67591c	8	12	the	the	DET
kw52j67591c	8	13	denv	denv	ADJ
kw52j67591c	8	14	genome	genome	NOUN
kw52j67591c	8	15	that	that	PRON
kw52j67591c	8	16	is	be	AUX
kw52j67591c	8	17	conserved	conserve	VERB
kw52j67591c	8	18	among	among	ADP
kw52j67591c	8	19	all	all	DET
kw52j67591c	8	20	four	four	NUM
kw52j67591c	8	21	dengue	dengue	NOUN
kw52j67591c	8	22	serotypes	serotype	NOUN
kw52j67591c	8	23	.	.	PUNCT
kw52j67591c	9	1	the	the	DET
kw52j67591c	9	2	ability	ability	NOUN
kw52j67591c	9	3	of	of	ADP
kw52j67591c	9	4	the	the	DET
kw52j67591c	9	5	ribozyme	ribozyme	NOUN
kw52j67591c	9	6	to	to	PART
kw52j67591c	9	7	cleave	cleave	VERB
kw52j67591c	9	8	this	this	DET
kw52j67591c	9	9	conserved	conserved	ADJ
kw52j67591c	9	10	sequence	sequence	NOUN
kw52j67591c	9	11	was	be	AUX
kw52j67591c	9	12	examined	examine	VERB
kw52j67591c	9	13	in	in	ADP
kw52j67591c	9	14	cell	cell	NOUN
kw52j67591c	9	15	culture	culture	NOUN
kw52j67591c	9	16	using	use	VERB
kw52j67591c	9	17	a	a	DET
kw52j67591c	9	18	5	5	NUM
kw52j67591c	9	19	'	'	PUNCT
kw52j67591c	9	20	denv	denv	NOUN
kw52j67591c	9	21	/	/	SYM
kw52j67591c	9	22	firefly	firefly	NOUN
kw52j67591c	9	23	luciferase	luciferase	NOUN
kw52j67591c	9	24	fusion	fusion	NOUN
kw52j67591c	9	25	target	target	NOUN
kw52j67591c	9	26	and	and	CCONJ
kw52j67591c	9	27	luciferase	luciferase	NOUN
kw52j67591c	9	28	assays	assay	NOUN
kw52j67591c	9	29	,	,	PUNCT
kw52j67591c	9	30	rt	rt	PROPN
kw52j67591c	9	31	-	-	PUNCT
kw52j67591c	9	32	pcr	pcr	NOUN
kw52j67591c	9	33	,	,	PUNCT
kw52j67591c	9	34	western	western	ADJ
kw52j67591c	9	35	dot	dot	NOUN
kw52j67591c	9	36	-	-	PUNCT
kw52j67591c	9	37	blot	blot	NOUN
kw52j67591c	9	38	,	,	PUNCT
kw52j67591c	9	39	and	and	CCONJ
kw52j67591c	9	40	in	in	ADP
kw52j67591c	9	41	-	-	PUNCT
kw52j67591c	9	42	vitro	vitro	X
kw52j67591c	9	43	cleavage	cleavage	NOUN
kw52j67591c	9	44	assays	assay	NOUN
kw52j67591c	9	45	.	.	PUNCT
kw52j67591c	10	1	our	our	PRON
kw52j67591c	10	2	analyses	analysis	NOUN
kw52j67591c	10	3	provide	provide	VERB
kw52j67591c	10	4	validation	validation	NOUN
kw52j67591c	10	5	of	of	ADP
kw52j67591c	10	6	this	this	DET
kw52j67591c	10	7	ribozyme	ribozyme	NOUN
kw52j67591c	10	8	as	as	ADP
kw52j67591c	10	9	a	a	DET
kw52j67591c	10	10	candidate	candidate	NOUN
kw52j67591c	10	11	effector	effector	NOUN
kw52j67591c	10	12	gene	gene	NOUN
kw52j67591c	10	13	for	for	ADP
kw52j67591c	10	14	dengue	dengue	PROPN
kw52j67591c	10	15	virus	virus	NOUN
kw52j67591c	10	16	refractivity	refractivity	NOUN
kw52j67591c	10	17	in	in	ADP
kw52j67591c	10	18	mosquito	mosquito	NOUN
kw52j67591c	10	19	cells	cell	NOUN
kw52j67591c	10	20	,	,	PUNCT
kw52j67591c	10	21	although	although	SCONJ
kw52j67591c	10	22	future	future	ADJ
kw52j67591c	10	23	work	work	NOUN
kw52j67591c	10	24	is	be	AUX
kw52j67591c	10	25	necessary	necessary	ADJ
kw52j67591c	10	26	to	to	PART
kw52j67591c	10	27	determine	determine	VERB
kw52j67591c	10	28	the	the	DET
kw52j67591c	10	29	extent	extent	NOUN
kw52j67591c	10	30	of	of	ADP
kw52j67591c	10	31	target	target	NOUN
kw52j67591c	10	32	cleavage	cleavage	NOUN
kw52j67591c	10	33	.	.	PUNCT
kw52j67591c	11	1	we	we	PRON
kw52j67591c	11	2	also	also	ADV
kw52j67591c	11	3	propose	propose	VERB
kw52j67591c	11	4	further	further	ADJ
kw52j67591c	11	5	development	development	NOUN
kw52j67591c	11	6	of	of	ADP
kw52j67591c	11	7	the	the	DET
kw52j67591c	11	8	ribozyme	ribozyme	NOUN
kw52j67591c	11	9	for	for	ADP
kw52j67591c	11	10	use	use	NOUN
kw52j67591c	11	11	as	as	ADP
kw52j67591c	11	12	an	an	DET
kw52j67591c	11	13	rna	rna	NOUN
kw52j67591c	11	14	drug	drug	NOUN
kw52j67591c	11	15	.	.	PUNCT