id sid tid token lemma pos jm214m93s11 1 1 this this DET jm214m93s11 1 2 thesis thesis NOUN jm214m93s11 1 3 presents present VERB jm214m93s11 1 4 three three NUM jm214m93s11 1 5 statistical statistical ADJ jm214m93s11 1 6 projects project NOUN jm214m93s11 1 7 on on ADP jm214m93s11 1 8 clinical clinical ADJ jm214m93s11 1 9 trial trial NOUN jm214m93s11 1 10 design design NOUN jm214m93s11 1 11 , , PUNCT jm214m93s11 1 12 climate climate NOUN jm214m93s11 1 13 projections projection NOUN jm214m93s11 1 14 and and CCONJ jm214m93s11 1 15 air air NOUN jm214m93s11 1 16 pollution pollution NOUN jm214m93s11 1 17 assessment assessment NOUN jm214m93s11 1 18 . . PUNCT jm214m93s11 2 1 the the DET jm214m93s11 2 2 first first ADJ jm214m93s11 2 3 project project NOUN jm214m93s11 2 4 is be AUX jm214m93s11 2 5 related relate VERB jm214m93s11 2 6 to to ADP jm214m93s11 2 7 clinical clinical ADJ jm214m93s11 2 8 trial trial NOUN jm214m93s11 2 9 phase phase NOUN jm214m93s11 2 10 i i PROPN jm214m93s11 2 11 / / SYM jm214m93s11 2 12 ii ii PROPN jm214m93s11 2 13 design design NOUN jm214m93s11 2 14 . . PUNCT jm214m93s11 3 1 the the DET jm214m93s11 3 2 objective objective NOUN jm214m93s11 3 3 is be AUX jm214m93s11 3 4 to to PART jm214m93s11 3 5 find find VERB jm214m93s11 3 6 the the DET jm214m93s11 3 7 optimal optimal ADJ jm214m93s11 3 8 dose dose NOUN jm214m93s11 3 9 for for ADP jm214m93s11 3 10 treating treat VERB jm214m93s11 3 11 patients patient NOUN jm214m93s11 3 12 . . PUNCT jm214m93s11 4 1 however however ADV jm214m93s11 4 2 , , PUNCT jm214m93s11 4 3 this this DET jm214m93s11 4 4 quantity quantity NOUN jm214m93s11 4 5 may may AUX jm214m93s11 4 6 differ differ VERB jm214m93s11 4 7 according accord VERB jm214m93s11 4 8 to to ADP jm214m93s11 4 9 the the DET jm214m93s11 4 10 patient patient NOUN jm214m93s11 4 11 's 's PART jm214m93s11 4 12 individual individual ADJ jm214m93s11 4 13 characteristics characteristic NOUN jm214m93s11 4 14 . . PUNCT jm214m93s11 5 1 in in ADP jm214m93s11 5 2 this this DET jm214m93s11 5 3 thesis thesis NOUN jm214m93s11 5 4 , , PUNCT jm214m93s11 5 5 a a DET jm214m93s11 5 6 novel novel ADJ jm214m93s11 5 7 bayesian bayesian NOUN jm214m93s11 5 8 adaptive adaptive ADJ jm214m93s11 5 9 randomization randomization NOUN jm214m93s11 5 10 design design NOUN jm214m93s11 5 11 is be AUX jm214m93s11 5 12 introduced introduce VERB jm214m93s11 5 13 to to PART jm214m93s11 5 14 evaluate evaluate VERB jm214m93s11 5 15 the the DET jm214m93s11 5 16 treatment treatment NOUN jm214m93s11 5 17 effect effect NOUN jm214m93s11 5 18 for for ADP jm214m93s11 5 19 different different ADJ jm214m93s11 5 20 levels level NOUN jm214m93s11 5 21 of of ADP jm214m93s11 5 22 radiotherapy radiotherapy NOUN jm214m93s11 5 23 . . PUNCT jm214m93s11 6 1 this this DET jm214m93s11 6 2 design design NOUN jm214m93s11 6 3 is be AUX jm214m93s11 6 4 motivated motivate VERB jm214m93s11 6 5 by by ADP jm214m93s11 6 6 an an DET jm214m93s11 6 7 ongoing ongoing ADJ jm214m93s11 6 8 lung lung NOUN jm214m93s11 6 9 cancel cancel VERB jm214m93s11 6 10 clinical clinical ADJ jm214m93s11 6 11 trial trial NOUN jm214m93s11 6 12 , , PUNCT jm214m93s11 6 13 which which PRON jm214m93s11 6 14 classified classify VERB jm214m93s11 6 15 patients patient NOUN jm214m93s11 6 16 in in ADP jm214m93s11 6 17 two two NUM jm214m93s11 6 18 subgroups subgroup NOUN jm214m93s11 6 19 based base VERB jm214m93s11 6 20 on on ADP jm214m93s11 6 21 their their PRON jm214m93s11 6 22 radiation radiation NOUN jm214m93s11 6 23 susceptibility susceptibility NOUN jm214m93s11 6 24 status status NOUN jm214m93s11 6 25 . . PUNCT jm214m93s11 7 1 patients patient NOUN jm214m93s11 7 2 in in ADP jm214m93s11 7 3 this this DET jm214m93s11 7 4 trial trial NOUN jm214m93s11 7 5 experience experience NOUN jm214m93s11 7 6 tumor tumor NOUN jm214m93s11 7 7 progression progression NOUN jm214m93s11 7 8 and and CCONJ jm214m93s11 7 9 normal normal ADJ jm214m93s11 7 10 tissue tissue NOUN jm214m93s11 7 11 complication complication NOUN jm214m93s11 7 12 . . PUNCT jm214m93s11 8 1 the the DET jm214m93s11 8 2 cause cause NOUN jm214m93s11 8 3 - - PUNCT jm214m93s11 8 4 specific specific ADJ jm214m93s11 8 5 hazard hazard NOUN jm214m93s11 8 6 method method NOUN jm214m93s11 8 7 is be AUX jm214m93s11 8 8 employed employ VERB jm214m93s11 8 9 to to PART jm214m93s11 8 10 model model VERB jm214m93s11 8 11 the the DET jm214m93s11 8 12 two two NUM jm214m93s11 8 13 competing compete VERB jm214m93s11 8 14 events event NOUN jm214m93s11 8 15 . . PUNCT jm214m93s11 9 1 simulation simulation NOUN jm214m93s11 9 2 studies study NOUN jm214m93s11 9 3 are be AUX jm214m93s11 9 4 conducted conduct VERB jm214m93s11 9 5 to to PART jm214m93s11 9 6 show show VERB jm214m93s11 9 7 the the DET jm214m93s11 9 8 good good ADJ jm214m93s11 9 9 operating operating NOUN jm214m93s11 9 10 characteristics characteristic NOUN jm214m93s11 9 11 of of ADP jm214m93s11 9 12 this this DET jm214m93s11 9 13 design design NOUN jm214m93s11 9 14 under under ADP jm214m93s11 9 15 multiple multiple ADJ jm214m93s11 9 16 scenarios.the scenarios.the DET jm214m93s11 9 17 second second ADJ jm214m93s11 9 18 project project NOUN jm214m93s11 9 19 is be AUX jm214m93s11 9 20 focused focus VERB jm214m93s11 9 21 on on ADP jm214m93s11 9 22 climate climate NOUN jm214m93s11 9 23 projections projection NOUN jm214m93s11 9 24 . . PUNCT jm214m93s11 10 1 decision decision NOUN jm214m93s11 10 2 making making NOUN jm214m93s11 10 3 under under ADP jm214m93s11 10 4 climate climate NOUN jm214m93s11 10 5 change change NOUN jm214m93s11 10 6 requires require VERB jm214m93s11 10 7 an an DET jm214m93s11 10 8 accurate accurate ADJ jm214m93s11 10 9 quantification quantification NOUN jm214m93s11 10 10 of of ADP jm214m93s11 10 11 the the DET jm214m93s11 10 12 uncertainty uncertainty NOUN jm214m93s11 10 13 in in ADP jm214m93s11 10 14 the the DET jm214m93s11 10 15 future future ADJ jm214m93s11 10 16 climate climate NOUN jm214m93s11 10 17 . . PUNCT jm214m93s11 11 1 physically physically ADV jm214m93s11 11 2 constrained constrain VERB jm214m93s11 11 3 projections projection NOUN jm214m93s11 11 4 , , PUNCT jm214m93s11 11 5 in in ADP jm214m93s11 11 6 the the DET jm214m93s11 11 7 presence presence NOUN jm214m93s11 11 8 of of ADP jm214m93s11 11 9 both both DET jm214m93s11 11 10 observations observation NOUN jm214m93s11 11 11 and and CCONJ jm214m93s11 11 12 climate climate NOUN jm214m93s11 11 13 simulations simulation NOUN jm214m93s11 11 14 , , PUNCT jm214m93s11 11 15 can can AUX jm214m93s11 11 16 be be AUX jm214m93s11 11 17 obtained obtain VERB jm214m93s11 11 18 by by ADP jm214m93s11 11 19 establishing establish VERB jm214m93s11 11 20 an an DET jm214m93s11 11 21 empirical empirical ADJ jm214m93s11 11 22 relationship relationship NOUN jm214m93s11 11 23 in in ADP jm214m93s11 11 24 the the DET jm214m93s11 11 25 historical historical ADJ jm214m93s11 11 26 period period NOUN jm214m93s11 11 27 , , PUNCT jm214m93s11 11 28 and and CCONJ jm214m93s11 11 29 use use VERB jm214m93s11 11 30 it it PRON jm214m93s11 11 31 to to PART jm214m93s11 11 32 correct correct VERB jm214m93s11 11 33 the the DET jm214m93s11 11 34 bias bias NOUN jm214m93s11 11 35 of of ADP jm214m93s11 11 36 future future ADJ jm214m93s11 11 37 simulations simulation NOUN jm214m93s11 11 38 . . PUNCT jm214m93s11 12 1 traditional traditional ADJ jm214m93s11 12 2 bias bias NOUN jm214m93s11 12 3 correction correction NOUN jm214m93s11 12 4 approaches approach NOUN jm214m93s11 12 5 do do AUX jm214m93s11 12 6 not not PART jm214m93s11 12 7 account account VERB jm214m93s11 12 8 for for ADP jm214m93s11 12 9 the the DET jm214m93s11 12 10 uncertainty uncertainty NOUN jm214m93s11 12 11 in in ADP jm214m93s11 12 12 the the DET jm214m93s11 12 13 climate climate NOUN jm214m93s11 12 14 simulation simulation NOUN jm214m93s11 12 15 and and CCONJ jm214m93s11 12 16 focus focus VERB jm214m93s11 12 17 on on ADP jm214m93s11 12 18 regionally regionally ADV jm214m93s11 12 19 aggregated aggregated ADJ jm214m93s11 12 20 variables variable NOUN jm214m93s11 12 21 without without ADP jm214m93s11 12 22 spatial spatial ADJ jm214m93s11 12 23 dependence dependence NOUN jm214m93s11 12 24 . . PUNCT jm214m93s11 13 1 a a DET jm214m93s11 13 2 new new ADJ jm214m93s11 13 3 statistical statistical ADJ jm214m93s11 13 4 model model NOUN jm214m93s11 13 5 is be AUX jm214m93s11 13 6 proposed propose VERB jm214m93s11 13 7 for for ADP jm214m93s11 13 8 bias bias NOUN jm214m93s11 13 9 correction correction NOUN jm214m93s11 13 10 of of ADP jm214m93s11 13 11 monthly monthly ADJ jm214m93s11 13 12 surface surface NOUN jm214m93s11 13 13 temperatures temperature NOUN jm214m93s11 13 14 with with ADP jm214m93s11 13 15 sparse sparse ADJ jm214m93s11 13 16 and and CCONJ jm214m93s11 13 17 interpretable interpretable ADJ jm214m93s11 13 18 spatial spatial ADJ jm214m93s11 13 19 structure structure NOUN jm214m93s11 13 20 and and CCONJ jm214m93s11 13 21 is be AUX jm214m93s11 13 22 used use VERB jm214m93s11 13 23 to to PART jm214m93s11 13 24 obtain obtain VERB jm214m93s11 13 25 future future ADJ jm214m93s11 13 26 projections projection NOUN jm214m93s11 13 27 with with ADP jm214m93s11 13 28 associated associated ADJ jm214m93s11 13 29 uncertainty uncertainty NOUN jm214m93s11 13 30 , , PUNCT jm214m93s11 13 31 using use VERB jm214m93s11 13 32 only only ADV jm214m93s11 13 33 a a DET jm214m93s11 13 34 small small ADJ jm214m93s11 13 35 ensemble ensemble NOUN jm214m93s11 13 36 of of ADP jm214m93s11 13 37 global global ADJ jm214m93s11 13 38 simulations.the simulations.the DET jm214m93s11 13 39 last last ADJ jm214m93s11 13 40 project project NOUN jm214m93s11 13 41 deals deal VERB jm214m93s11 13 42 with with ADP jm214m93s11 13 43 the the DET jm214m93s11 13 44 connection connection NOUN jm214m93s11 13 45 between between ADP jm214m93s11 13 46 the the DET jm214m93s11 13 47 ongoing ongoing ADJ jm214m93s11 13 48 covid-19 covid-19 PROPN jm214m93s11 13 49 pandemic pandemic ADJ jm214m93s11 13 50 and and CCONJ jm214m93s11 13 51 air air NOUN jm214m93s11 13 52 pollution pollution NOUN jm214m93s11 13 53 . . PUNCT jm214m93s11 14 1 exposure exposure NOUN jm214m93s11 14 2 to to ADP jm214m93s11 14 3 degraded degrade VERB jm214m93s11 14 4 air air NOUN jm214m93s11 14 5 quality quality NOUN jm214m93s11 14 6 leads lead VERB jm214m93s11 14 7 to to ADP jm214m93s11 14 8 increased increase VERB jm214m93s11 14 9 premature premature ADJ jm214m93s11 14 10 mortality mortality NOUN jm214m93s11 14 11 from from ADP jm214m93s11 14 12 cardiovascular cardiovascular ADJ jm214m93s11 14 13 and and CCONJ jm214m93s11 14 14 respiratory respiratory ADJ jm214m93s11 14 15 diseases disease NOUN jm214m93s11 14 16 . . PUNCT jm214m93s11 15 1 among among ADP jm214m93s11 15 2 the the DET jm214m93s11 15 3 far far ADV jm214m93s11 15 4 - - PUNCT jm214m93s11 15 5 reaching reach VERB jm214m93s11 15 6 implications implication NOUN jm214m93s11 15 7 of of ADP jm214m93s11 15 8 the the DET jm214m93s11 15 9 ongoing ongoing ADJ jm214m93s11 15 10 pandemic pandemic NOUN jm214m93s11 15 11 , , PUNCT jm214m93s11 15 12 a a DET jm214m93s11 15 13 significant significant ADJ jm214m93s11 15 14 air air NOUN jm214m93s11 15 15 quality quality NOUN jm214m93s11 15 16 improvement improvement NOUN jm214m93s11 15 17 has have AUX jm214m93s11 15 18 been be AUX jm214m93s11 15 19 observed observe VERB jm214m93s11 15 20 after after ADP jm214m93s11 15 21 the the DET jm214m93s11 15 22 lockdowns lockdown NOUN jm214m93s11 15 23 imposed impose VERB jm214m93s11 15 24 by by ADP jm214m93s11 15 25 many many ADJ jm214m93s11 15 26 countries country NOUN jm214m93s11 15 27 . . PUNCT jm214m93s11 16 1 we we PRON jm214m93s11 16 2 presented present VERB jm214m93s11 16 3 the the DET jm214m93s11 16 4 first first ADJ jm214m93s11 16 5 comprehensive comprehensive ADJ jm214m93s11 16 6 study study NOUN jm214m93s11 16 7 investigating investigate VERB jm214m93s11 16 8 the the DET jm214m93s11 16 9 connection connection NOUN jm214m93s11 16 10 between between ADP jm214m93s11 16 11 interventions intervention NOUN jm214m93s11 16 12 adopted adopt VERB jm214m93s11 16 13 to to PART jm214m93s11 16 14 control control VERB jm214m93s11 16 15 a a DET jm214m93s11 16 16 pandemic pandemic ADJ jm214m93s11 16 17 spread spread NOUN jm214m93s11 16 18 and and CCONJ jm214m93s11 16 19 subsequent subsequent ADJ jm214m93s11 16 20 effects effect NOUN jm214m93s11 16 21 on on ADP jm214m93s11 16 22 large large ADJ jm214m93s11 16 23 - - PUNCT jm214m93s11 16 24 scale scale NOUN jm214m93s11 16 25 air air NOUN jm214m93s11 16 26 quality quality NOUN jm214m93s11 16 27 and and CCONJ jm214m93s11 16 28 human human ADJ jm214m93s11 16 29 health health NOUN jm214m93s11 16 30 . . PUNCT jm214m93s11 17 1 we we PRON jm214m93s11 17 2 use use VERB jm214m93s11 17 3 fine fine ADJ jm214m93s11 17 4 particulate particulate NOUN jm214m93s11 17 5 matter matter NOUN jm214m93s11 17 6 observations observation NOUN jm214m93s11 17 7 in in ADP jm214m93s11 17 8 europe europe PROPN jm214m93s11 17 9 and and CCONJ jm214m93s11 17 10 china china PROPN jm214m93s11 17 11 during during ADP jm214m93s11 17 12 2016 2016 NUM jm214m93s11 17 13 - - SYM jm214m93s11 17 14 2020 2020 NUM jm214m93s11 17 15 and and CCONJ jm214m93s11 17 16 integrate integrate VERB jm214m93s11 17 17 them they PRON jm214m93s11 17 18 with with ADP jm214m93s11 17 19 chemical chemical ADJ jm214m93s11 17 20 transport transport NOUN jm214m93s11 17 21 model model NOUN jm214m93s11 17 22 simulations simulation NOUN jm214m93s11 17 23 as as ADV jm214m93s11 17 24 well well ADV jm214m93s11 17 25 as as ADP jm214m93s11 17 26 the the DET jm214m93s11 17 27 latest late ADJ jm214m93s11 17 28 epidemiological epidemiological ADJ jm214m93s11 17 29 studies study NOUN jm214m93s11 17 30 to to PART jm214m93s11 17 31 quantify quantify VERB jm214m93s11 17 32 the the DET jm214m93s11 17 33 health health NOUN jm214m93s11 17 34 benefits benefit NOUN jm214m93s11 17 35 during during ADP jm214m93s11 17 36 the the DET jm214m93s11 17 37 pandemic pandemic NOUN jm214m93s11 17 38 . . PUNCT