id sid tid token lemma pos jh343r09c54 1 1 the the DET jh343r09c54 1 2 aortic aortic NOUN jh343r09c54 1 3 valve valve NOUN jh343r09c54 1 4 is be AUX jh343r09c54 1 5 one one NUM jh343r09c54 1 6 of of ADP jh343r09c54 1 7 the the DET jh343r09c54 1 8 four four NUM jh343r09c54 1 9 valves valve NOUN jh343r09c54 1 10 of of ADP jh343r09c54 1 11 the the DET jh343r09c54 1 12 heart heart NOUN jh343r09c54 1 13 , , PUNCT jh343r09c54 1 14 responsible responsible ADJ jh343r09c54 1 15 for for ADP jh343r09c54 1 16 the the DET jh343r09c54 1 17 unidirectional unidirectional ADJ jh343r09c54 1 18 flow flow NOUN jh343r09c54 1 19 of of ADP jh343r09c54 1 20 blood blood NOUN jh343r09c54 1 21 from from ADP jh343r09c54 1 22 the the DET jh343r09c54 1 23 left left ADJ jh343r09c54 1 24 ventricle ventricle NOUN jh343r09c54 1 25 to to ADP jh343r09c54 1 26 the the DET jh343r09c54 1 27 aorta aorta NOUN jh343r09c54 1 28 . . PUNCT jh343r09c54 2 1 the the DET jh343r09c54 2 2 most most ADV jh343r09c54 2 3 common common ADJ jh343r09c54 2 4 aortic aortic NOUN jh343r09c54 2 5 valve valve NOUN jh343r09c54 2 6 disease disease NOUN jh343r09c54 2 7 , , PUNCT jh343r09c54 2 8 calcific calcific PROPN jh343r09c54 2 9 aortic aortic NOUN jh343r09c54 2 10 stenosis stenosis NOUN jh343r09c54 2 11 , , PUNCT jh343r09c54 2 12 is be AUX jh343r09c54 2 13 characterized characterize VERB jh343r09c54 2 14 by by ADP jh343r09c54 2 15 the the DET jh343r09c54 2 16 narrowing narrowing NOUN jh343r09c54 2 17 of of ADP jh343r09c54 2 18 the the DET jh343r09c54 2 19 valve valve NOUN jh343r09c54 2 20 due due ADP jh343r09c54 2 21 to to ADP jh343r09c54 2 22 the the DET jh343r09c54 2 23 presence presence NOUN jh343r09c54 2 24 of of ADP jh343r09c54 2 25 calcified calcify VERB jh343r09c54 2 26 nodules nodule NOUN jh343r09c54 2 27 on on ADP jh343r09c54 2 28 the the DET jh343r09c54 2 29 valvular valvular ADJ jh343r09c54 2 30 leaflets leaflet NOUN jh343r09c54 2 31 and and CCONJ jh343r09c54 2 32 is be AUX jh343r09c54 2 33 present present ADJ jh343r09c54 2 34 in in ADP jh343r09c54 2 35 8 8 NUM jh343r09c54 2 36 % % NOUN jh343r09c54 2 37 of of ADP jh343r09c54 2 38 the the DET jh343r09c54 2 39 population population NOUN jh343r09c54 2 40 above above ADP jh343r09c54 2 41 65 65 NUM jh343r09c54 2 42 years year NOUN jh343r09c54 2 43 of of ADP jh343r09c54 2 44 age age NOUN jh343r09c54 2 45 . . PUNCT jh343r09c54 3 1 the the DET jh343r09c54 3 2 processes process NOUN jh343r09c54 3 3 by by ADP jh343r09c54 3 4 which which PRON jh343r09c54 3 5 calcification calcification NOUN jh343r09c54 3 6 occurs occur VERB jh343r09c54 3 7 are be AUX jh343r09c54 3 8 poorly poorly ADV jh343r09c54 3 9 understood understand VERB jh343r09c54 3 10 . . PUNCT jh343r09c54 4 1 blood blood NOUN jh343r09c54 4 2 exerts exert VERB jh343r09c54 4 3 a a DET jh343r09c54 4 4 combination combination NOUN jh343r09c54 4 5 of of ADP jh343r09c54 4 6 forces force NOUN jh343r09c54 4 7 on on ADP jh343r09c54 4 8 the the DET jh343r09c54 4 9 valve valve NOUN jh343r09c54 4 10 leaflets leaflet NOUN jh343r09c54 4 11 , , PUNCT jh343r09c54 4 12 which which PRON jh343r09c54 4 13 are be AUX jh343r09c54 4 14 believed believe VERB jh343r09c54 4 15 to to PART jh343r09c54 4 16 have have VERB jh343r09c54 4 17 a a DET jh343r09c54 4 18 significant significant ADJ jh343r09c54 4 19 effect effect NOUN jh343r09c54 4 20 on on ADP jh343r09c54 4 21 valvular valvular ADJ jh343r09c54 4 22 disease disease NOUN jh343r09c54 4 23 progression progression NOUN jh343r09c54 4 24 . . PUNCT jh343r09c54 5 1 this this DET jh343r09c54 5 2 study study NOUN jh343r09c54 5 3 investigates investigate VERB jh343r09c54 5 4 the the DET jh343r09c54 5 5 role role NOUN jh343r09c54 5 6 played play VERB jh343r09c54 5 7 by by ADP jh343r09c54 5 8 blood blood NOUN jh343r09c54 5 9 flow flow NOUN jh343r09c54 5 10 dynamics dynamic NOUN jh343r09c54 5 11 and and CCONJ jh343r09c54 5 12 prospective prospective ADJ jh343r09c54 5 13 mechanosensitive mechanosensitive ADJ jh343r09c54 5 14 molecules molecule NOUN jh343r09c54 5 15 in in ADP jh343r09c54 5 16 the the DET jh343r09c54 5 17 development development NOUN jh343r09c54 5 18 of of ADP jh343r09c54 5 19 aortic aortic NOUN jh343r09c54 5 20 valve valve NOUN jh343r09c54 5 21 disease disease NOUN jh343r09c54 5 22 . . PUNCT jh343r09c54 6 1 these these DET jh343r09c54 6 2 insights insight NOUN jh343r09c54 6 3 may may AUX jh343r09c54 6 4 aid aid VERB jh343r09c54 6 5 in in ADP jh343r09c54 6 6 development development NOUN jh343r09c54 6 7 of of ADP jh343r09c54 6 8 pharmacological pharmacological ADJ jh343r09c54 6 9 management management NOUN jh343r09c54 6 10 of of ADP jh343r09c54 6 11 valvular valvular ADJ jh343r09c54 6 12 disease disease NOUN jh343r09c54 6 13 . . PUNCT