id	sid	tid	token	lemma	pos
j3860576970	1	1	the	the	DET
j3860576970	1	2	canonical	canonical	ADJ
j3860576970	1	3	wnt	wnt	PROPN
j3860576970	1	4	/	/	SYM
j3860576970	1	5	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	1	6	signaling	signal	VERB
j3860576970	1	7	is	be	AUX
j3860576970	1	8	involved	involve	VERB
j3860576970	1	9	in	in	ADP
j3860576970	1	10	the	the	DET
j3860576970	1	11	remodeling	remodeling	NOUN
j3860576970	1	12	of	of	ADP
j3860576970	1	13	epithelial	epithelial	ADJ
j3860576970	1	14	tissue	tissue	NOUN
j3860576970	1	15	during	during	ADP
j3860576970	1	16	early	early	ADJ
j3860576970	1	17	embryonic	embryonic	ADJ
j3860576970	1	18	development	development	NOUN
j3860576970	1	19	.	.	PUNCT
j3860576970	2	1	an	an	DET
j3860576970	2	2	essential	essential	ADJ
j3860576970	2	3	component	component	NOUN
j3860576970	2	4	of	of	ADP
j3860576970	2	5	the	the	DET
j3860576970	2	6	canonical	canonical	ADJ
j3860576970	2	7	wnt	wnt	PROPN
j3860576970	2	8	pathway	pathway	NOUN
j3860576970	2	9	is	be	AUX
j3860576970	2	10	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	PROPN
j3860576970	2	11	,	,	PUNCT
j3860576970	2	12	whose	whose	DET
j3860576970	2	13	dual	dual	ADJ
j3860576970	2	14	role	role	NOUN
j3860576970	2	15	in	in	ADP
j3860576970	2	16	the	the	DET
j3860576970	2	17	cell	cell	NOUN
j3860576970	2	18	allows	allow	VERB
j3860576970	2	19	it	it	PRON
j3860576970	2	20	to	to	PART
j3860576970	2	21	function	function	VERB
j3860576970	2	22	either	either	CCONJ
j3860576970	2	23	as	as	ADP
j3860576970	2	24	a	a	DET
j3860576970	2	25	bridge	bridge	NOUN
j3860576970	2	26	between	between	ADP
j3860576970	2	27	cadherins	cadherin	NOUN
j3860576970	2	28	and	and	CCONJ
j3860576970	2	29	the	the	DET
j3860576970	2	30	actin	actin	NOUN
j3860576970	2	31	cytoskeleton	cytoskeleton	NOUN
j3860576970	2	32	at	at	ADP
j3860576970	2	33	the	the	DET
j3860576970	2	34	adherens	adherens	NOUN
j3860576970	2	35	junctions	junction	NOUN
j3860576970	2	36	,	,	PUNCT
j3860576970	2	37	or	or	CCONJ
j3860576970	2	38	as	as	ADP
j3860576970	2	39	a	a	DET
j3860576970	2	40	transcriptional	transcriptional	ADJ
j3860576970	2	41	transactivator	transactivator	NOUN
j3860576970	2	42	of	of	ADP
j3860576970	2	43	wnt	wnt	PROPN
j3860576970	2	44	target	target	NOUN
j3860576970	2	45	genes	gene	NOUN
j3860576970	2	46	when	when	SCONJ
j3860576970	2	47	bound	bind	VERB
j3860576970	2	48	to	to	PART
j3860576970	2	49	lymphoid	lymphoid	NOUN
j3860576970	2	50	enhancer	enhancer	NOUN
j3860576970	2	51	factor	factor	NOUN
j3860576970	2	52	(	(	PUNCT
j3860576970	2	53	lef)/	lef)/	PROPN
j3860576970	2	54	t	t	PROPN
j3860576970	2	55	-	-	PUNCT
j3860576970	2	56	cell	cell	NOUN
j3860576970	2	57	factor	factor	NOUN
j3860576970	2	58	(	(	PUNCT
j3860576970	2	59	tcf	tcf	NOUN
j3860576970	2	60	)	)	PUNCT
j3860576970	2	61	family	family	NOUN
j3860576970	2	62	of	of	ADP
j3860576970	2	63	transcription	transcription	NOUN
j3860576970	2	64	factors	factor	NOUN
j3860576970	2	65	.	.	PUNCT
j3860576970	3	1	the	the	DET
j3860576970	3	2	dual	dual	ADJ
j3860576970	3	3	function	function	NOUN
j3860576970	3	4	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	3	5	in	in	ADP
j3860576970	3	6	cell	cell	NOUN
j3860576970	3	7	adhesion	adhesion	NOUN
j3860576970	3	8	and	and	CCONJ
j3860576970	3	9	transcription	transcription	NOUN
j3860576970	3	10	is	be	AUX
j3860576970	3	11	tightly	tightly	ADV
j3860576970	3	12	regulated	regulate	VERB
j3860576970	3	13	in	in	ADP
j3860576970	3	14	vertebrates	vertebrate	NOUN
j3860576970	3	15	in	in	ADP
j3860576970	3	16	order	order	NOUN
j3860576970	3	17	to	to	PART
j3860576970	3	18	maintain	maintain	VERB
j3860576970	3	19	a	a	DET
j3860576970	3	20	balanced	balanced	ADJ
j3860576970	3	21	level	level	NOUN
j3860576970	3	22	of	of	ADP
j3860576970	3	23	canonical	canonical	ADJ
j3860576970	3	24	wnt	wnt	PROPN
j3860576970	3	25	signaling	signaling	NOUN
j3860576970	3	26	.	.	PUNCT
j3860576970	4	1	deregulation	deregulation	NOUN
j3860576970	4	2	of	of	ADP
j3860576970	4	3	this	this	DET
j3860576970	4	4	conserved	conserve	VERB
j3860576970	4	5	developmental	developmental	ADJ
j3860576970	4	6	pathway	pathway	NOUN
j3860576970	4	7	is	be	AUX
j3860576970	4	8	frequently	frequently	ADV
j3860576970	4	9	associated	associate	VERB
j3860576970	4	10	with	with	ADP
j3860576970	4	11	disease	disease	NOUN
j3860576970	4	12	,	,	PUNCT
j3860576970	4	13	especially	especially	ADV
j3860576970	4	14	in	in	ADP
j3860576970	4	15	pre	pre	ADJ
j3860576970	4	16	-	-	ADJ
j3860576970	4	17	malignant	malignant	ADJ
j3860576970	4	18	lesions	lesion	NOUN
j3860576970	4	19	and	and	CCONJ
j3860576970	4	20	metastatic	metastatic	ADJ
j3860576970	4	21	disease	disease	NOUN
j3860576970	4	22	.	.	PUNCT
j3860576970	5	1	in	in	ADP
j3860576970	5	2	this	this	DET
j3860576970	5	3	research	research	NOUN
j3860576970	5	4	dissertation	dissertation	NOUN
j3860576970	5	5	,	,	PUNCT
j3860576970	5	6	a	a	DET
j3860576970	5	7	novel	novel	ADJ
j3860576970	5	8	role	role	NOUN
j3860576970	5	9	for	for	ADP
j3860576970	5	10	the	the	DET
j3860576970	5	11	arf6	arf6	PROPN
j3860576970	5	12	gtpase	gtpase	NOUN
j3860576970	5	13	in	in	ADP
j3860576970	5	14	the	the	DET
j3860576970	5	15	regulation	regulation	NOUN
j3860576970	5	16	of	of	ADP
j3860576970	5	17	wnt	wnt	PROPN
j3860576970	5	18	/	/	SYM
j3860576970	5	19	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	5	20	signaling	signal	VERB
j3860576970	5	21	via	via	ADP
j3860576970	5	22	its	its	PRON
j3860576970	5	23	effect	effect	NOUN
j3860576970	5	24	on	on	ADP
j3860576970	5	25	the	the	DET
j3860576970	5	26	turnover	turnover	NOUN
j3860576970	5	27	of	of	ADP
j3860576970	5	28	adhesion	adhesion	NOUN
j3860576970	5	29	molecules	molecule	NOUN
j3860576970	5	30	in	in	ADP
j3860576970	5	31	madin	madin	ADJ
j3860576970	5	32	-	-	PUNCT
j3860576970	5	33	darby	darby	ADJ
j3860576970	5	34	canine	canine	NOUN
j3860576970	5	35	kidney	kidney	NOUN
j3860576970	5	36	(	(	PUNCT
j3860576970	5	37	mdck	mdck	ADJ
j3860576970	5	38	)	)	PUNCT
j3860576970	5	39	epithelial	epithelial	ADJ
j3860576970	5	40	cells	cell	NOUN
j3860576970	5	41	,	,	PUNCT
j3860576970	5	42	is	be	AUX
j3860576970	5	43	demonstrated	demonstrate	VERB
j3860576970	5	44	.	.	PUNCT
j3860576970	6	1	activation	activation	NOUN
j3860576970	6	2	of	of	ADP
j3860576970	6	3	arf6	arf6	PROPN
j3860576970	6	4	during	during	ADP
j3860576970	6	5	canonical	canonical	PROPN
j3860576970	6	6	wnt	wnt	PROPN
j3860576970	6	7	signaling	signal	VERB
j3860576970	6	8	led	lead	VERB
j3860576970	6	9	to	to	AUX
j3860576970	6	10	intracellular	intracellular	ADJ
j3860576970	6	11	accumulation	accumulation	NOUN
j3860576970	6	12	of	of	ADP
j3860576970	6	13	pools	pool	NOUN
j3860576970	6	14	of	of	ADP
j3860576970	6	15	active	active	ADJ
j3860576970	6	16	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	6	17	by	by	ADP
j3860576970	6	18	promoting	promote	VERB
j3860576970	6	19	e	e	NOUN
j3860576970	6	20	-	-	ADJ
j3860576970	6	21	cadherin	cadherin	ADJ
j3860576970	6	22	endocytosis	endocytosis	NOUN
j3860576970	6	23	and	and	CCONJ
j3860576970	6	24	triggering	trigger	VERB
j3860576970	6	25	an	an	DET
j3860576970	6	26	intracellular	intracellular	ADJ
j3860576970	6	27	erk	erk	NOUN
j3860576970	6	28	-	-	PUNCT
j3860576970	6	29	ck2	ck2	NOUN
j3860576970	6	30	signaling	signal	VERB
j3860576970	6	31	cascade	cascade	NOUN
j3860576970	6	32	that	that	PRON
j3860576970	6	33	results	result	VERB
j3860576970	6	34	in	in	ADP
j3860576970	6	35	the	the	DET
j3860576970	6	36	dissociation	dissociation	NOUN
j3860576970	6	37	of	of	ADP
j3860576970	6	38	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	6	39	from	from	ADP
j3860576970	6	40	ìäå_ìâå±-catenin	ìäå_ìâå±-catenin	NUM
j3860576970	6	41	complexes	complex	NOUN
j3860576970	6	42	.	.	PUNCT
j3860576970	7	1	the	the	DET
j3860576970	7	2	contribution	contribution	NOUN
j3860576970	7	3	of	of	ADP
j3860576970	7	4	membrane	membrane	NOUN
j3860576970	7	5	bound	bind	VERB
j3860576970	7	6	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	PROPN
j3860576970	7	7	to	to	PART
j3860576970	7	8	transcription	transcription	NOUN
j3860576970	7	9	initiation	initiation	NOUN
j3860576970	7	10	was	be	AUX
j3860576970	7	11	based	base	VERB
j3860576970	7	12	on	on	ADP
j3860576970	7	13	the	the	DET
j3860576970	7	14	presence	presence	NOUN
j3860576970	7	15	of	of	ADP
j3860576970	7	16	n	n	NOUN
j3860576970	7	17	-	-	PUNCT
j3860576970	7	18	terminally	terminally	NOUN
j3860576970	7	19	dephosphorylated	dephosphorylate	VERB
j3860576970	7	20	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	PROPN
j3860576970	7	21	,	,	PUNCT
j3860576970	7	22	which	which	PRON
j3860576970	7	23	has	have	AUX
j3860576970	7	24	been	be	AUX
j3860576970	7	25	shown	show	VERB
j3860576970	7	26	to	to	PART
j3860576970	7	27	mediate	mediate	VERB
j3860576970	7	28	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	7	29	transactivation	transactivation	NOUN
j3860576970	7	30	.	.	PUNCT
j3860576970	8	1	furthermore	furthermore	ADV
j3860576970	8	2	,	,	PUNCT
j3860576970	8	3	erk	erk	PROPN
j3860576970	8	4	phosphorylates	phosphorylate	NOUN
j3860576970	8	5	lrp6	lrp6	PROPN
j3860576970	8	6	to	to	PART
j3860576970	8	7	amplify	amplify	VERB
j3860576970	8	8	the	the	DET
j3860576970	8	9	wnt	wnt	PROPN
j3860576970	8	10	transduction	transduction	NOUN
j3860576970	8	11	pathway	pathway	NOUN
j3860576970	8	12	.	.	PUNCT
j3860576970	9	1	wnt	wnt	PROPN
j3860576970	9	2	/	/	SYM
j3860576970	9	3	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	9	4	signaling	signal	VERB
j3860576970	9	5	also	also	ADV
j3860576970	9	6	initiated	initiate	VERB
j3860576970	9	7	a	a	DET
j3860576970	9	8	proliferation	proliferation	NOUN
j3860576970	9	9	response	response	NOUN
j3860576970	9	10	that	that	PRON
j3860576970	9	11	correlated	correlate	VERB
j3860576970	9	12	with	with	ADP
j3860576970	9	13	the	the	DET
j3860576970	9	14	luminal	luminal	ADJ
j3860576970	9	15	filling	filling	NOUN
j3860576970	9	16	of	of	ADP
j3860576970	9	17	epithelial	epithelial	ADJ
j3860576970	9	18	glandular	glandular	ADJ
j3860576970	9	19	structures	structure	NOUN
j3860576970	9	20	.	.	PUNCT
j3860576970	10	1	sustained	sustained	ADJ
j3860576970	10	2	proliferation	proliferation	NOUN
j3860576970	10	3	of	of	ADP
j3860576970	10	4	cells	cell	NOUN
j3860576970	10	5	may	may	AUX
j3860576970	10	6	be	be	AUX
j3860576970	10	7	facilitated	facilitate	VERB
j3860576970	10	8	by	by	ADP
j3860576970	10	9	arf6	arf6	PROPN
j3860576970	10	10	-	-	PUNCT
j3860576970	10	11	dependent	dependent	ADJ
j3860576970	10	12	endocytosis	endocytosis	NOUN
j3860576970	10	13	of	of	ADP
j3860576970	10	14	the	the	DET
j3860576970	10	15	lrp6	lrp6	NOUN
j3860576970	10	16	receptor	receptor	NOUN
j3860576970	10	17	and	and	CCONJ
j3860576970	10	18	erk	erk	PROPN
j3860576970	10	19	kinase	kinase	PROPN
j3860576970	10	20	.	.	PUNCT
j3860576970	11	1	furthermore	furthermore	ADV
j3860576970	11	2	,	,	PUNCT
j3860576970	11	3	we	we	PRON
j3860576970	11	4	showed	show	VERB
j3860576970	11	5	that	that	SCONJ
j3860576970	11	6	the	the	DET
j3860576970	11	7	erk	erk	PROPN
j3860576970	11	8	-	-	PUNCT
j3860576970	11	9	ck2	ck2	PROPN
j3860576970	11	10	signaling	signal	VERB
j3860576970	11	11	cascade	cascade	NOUN
j3860576970	11	12	mediates	mediate	VERB
j3860576970	11	13	the	the	DET
j3860576970	11	14	proliferation	proliferation	NOUN
j3860576970	11	15	response	response	NOUN
j3860576970	11	16	that	that	PRON
j3860576970	11	17	sustains	sustain	VERB
j3860576970	11	18	luminal	luminal	VERB
j3860576970	11	19	filling	fill	VERB
j3860576970	11	20	in	in	ADP
j3860576970	11	21	cysts	cyst	NOUN
j3860576970	11	22	and	and	CCONJ
j3860576970	11	23	acinar	acinar	NOUN
j3860576970	11	24	structures	structure	NOUN
j3860576970	11	25	.	.	PUNCT
j3860576970	12	1	finally	finally	ADV
j3860576970	12	2	,	,	PUNCT
j3860576970	12	3	the	the	DET
j3860576970	12	4	identification	identification	NOUN
j3860576970	12	5	of	of	ADP
j3860576970	12	6	consensus	consensus	NOUN
j3860576970	12	7	sites	site	NOUN
j3860576970	12	8	for	for	ADP
j3860576970	12	9	interaction	interaction	NOUN
j3860576970	12	10	with	with	ADP
j3860576970	12	11	transcription	transcription	NOUN
j3860576970	12	12	factors	factor	NOUN
j3860576970	12	13	regulated	regulate	VERB
j3860576970	12	14	by	by	ADP
j3860576970	12	15	wnt	wnt	PRON
j3860576970	12	16	in	in	ADP
j3860576970	12	17	the	the	DET
j3860576970	12	18	arf6	arf6	PROPN
j3860576970	12	19	promoter	promoter	NOUN
j3860576970	12	20	is	be	AUX
j3860576970	12	21	indicative	indicative	ADJ
j3860576970	12	22	of	of	ADP
j3860576970	12	23	potential	potential	ADJ
j3860576970	12	24	transcriptional	transcriptional	NOUN
j3860576970	12	25	control	control	NOUN
j3860576970	12	26	by	by	ADP
j3860576970	12	27	signaling	signal	VERB
j3860576970	12	28	pathways	pathway	NOUN
j3860576970	12	29	that	that	PRON
j3860576970	12	30	contribute	contribute	VERB
j3860576970	12	31	to	to	ADP
j3860576970	12	32	epithelial	epithelial	ADJ
j3860576970	12	33	-	-	PUNCT
j3860576970	12	34	mesenchymal	mesenchymal	NOUN
j3860576970	12	35	transitions	transition	NOUN
j3860576970	12	36	.	.	PUNCT
j3860576970	13	1	in	in	ADP
j3860576970	13	2	summary	summary	NOUN
j3860576970	13	3	,	,	PUNCT
j3860576970	13	4	this	this	DET
j3860576970	13	5	study	study	NOUN
j3860576970	13	6	identifies	identify	VERB
j3860576970	13	7	arf6	arf6	PROPN
j3860576970	13	8	as	as	ADP
j3860576970	13	9	a	a	DET
j3860576970	13	10	new	new	ADJ
j3860576970	13	11	target	target	NOUN
j3860576970	13	12	of	of	ADP
j3860576970	13	13	wnt	wnt	PROPN
j3860576970	13	14	/	/	SYM
j3860576970	13	15	ìäå_ìâå_-catenin	ìäå_ìâå_-catenin	NUM
j3860576970	13	16	activation	activation	NOUN
j3860576970	13	17	with	with	ADP
j3860576970	13	18	a	a	DET
j3860576970	13	19	therapeutic	therapeutic	ADJ
j3860576970	13	20	potential	potential	NOUN
j3860576970	13	21	in	in	ADP
j3860576970	13	22	pre	pre	ADJ
j3860576970	13	23	-	-	ADJ
j3860576970	13	24	invasive	invasive	ADJ
j3860576970	13	25	lesions	lesion	NOUN
j3860576970	13	26	of	of	ADP
j3860576970	13	27	glandular	glandular	ADJ
j3860576970	13	28	epithelial	epithelial	ADJ
j3860576970	13	29	tissue	tissue	NOUN
j3860576970	13	30	.	.	PUNCT