id sid tid token lemma pos hd76rx93b84 1 1 ultraviolet ultraviolet ADJ hd76rx93b84 1 2 irradiation irradiation NOUN hd76rx93b84 1 3 of of ADP hd76rx93b84 1 4 dna dna PROPN hd76rx93b84 1 5 induces induce VERB hd76rx93b84 1 6 formation formation NOUN hd76rx93b84 1 7 of of ADP hd76rx93b84 1 8 two two NUM hd76rx93b84 1 9 principal principal ADJ hd76rx93b84 1 10 photoproducts photoproduct NOUN hd76rx93b84 1 11 , , PUNCT hd76rx93b84 1 12 the the DET hd76rx93b84 1 13 more more ADV hd76rx93b84 1 14 prevalent prevalent ADJ hd76rx93b84 1 15 , , PUNCT hd76rx93b84 1 16 less less ADV hd76rx93b84 1 17 mutagenic mutagenic ADJ hd76rx93b84 1 18 cyclobutane cyclobutane NOUN hd76rx93b84 1 19 pyrimidine pyrimidine NOUN hd76rx93b84 1 20 dimer dimer NOUN hd76rx93b84 1 21 ( ( PUNCT hd76rx93b84 1 22 cpd cpd NOUN hd76rx93b84 1 23 ) ) PUNCT hd76rx93b84 1 24 and and CCONJ hd76rx93b84 1 25 the the DET hd76rx93b84 1 26 less less ADV hd76rx93b84 1 27 prevalent prevalent ADJ hd76rx93b84 1 28 , , PUNCT hd76rx93b84 1 29 more more ADV hd76rx93b84 1 30 mutagenic mutagenic ADJ hd76rx93b84 1 31 ( ( PUNCT hd76rx93b84 1 32 6 6 NUM hd76rx93b84 1 33 - - SYM hd76rx93b84 1 34 4 4 NUM hd76rx93b84 1 35 ) ) PUNCT hd76rx93b84 1 36 photoproduct photoproduct NOUN hd76rx93b84 1 37 , , PUNCT hd76rx93b84 1 38 ( ( PUNCT hd76rx93b84 1 39 pp pp ADV hd76rx93b84 1 40 ) ) PUNCT hd76rx93b84 1 41 . . PUNCT hd76rx93b84 2 1 these these DET hd76rx93b84 2 2 covalent covalent NOUN hd76rx93b84 2 3 dimers dimer NOUN hd76rx93b84 2 4 block block VERB hd76rx93b84 2 5 cell cell NOUN hd76rx93b84 2 6 replication replication NOUN hd76rx93b84 2 7 and and CCONJ hd76rx93b84 2 8 transcription transcription NOUN hd76rx93b84 2 9 , , PUNCT hd76rx93b84 2 10 corrupting corrupt VERB hd76rx93b84 2 11 genetic genetic ADJ hd76rx93b84 2 12 information information NOUN hd76rx93b84 2 13 and and CCONJ hd76rx93b84 2 14 leading lead VERB hd76rx93b84 2 15 to to ADP hd76rx93b84 2 16 cell cell NOUN hd76rx93b84 2 17 death death NOUN hd76rx93b84 2 18 and and CCONJ hd76rx93b84 2 19 skin skin NOUN hd76rx93b84 2 20 cancer cancer NOUN hd76rx93b84 2 21 . . PUNCT hd76rx93b84 3 1 in in ADP hd76rx93b84 3 2 bacteria bacteria NOUN hd76rx93b84 3 3 and and CCONJ hd76rx93b84 3 4 archaea archaea ADJ hd76rx93b84 3 5 kingdoms kingdom NOUN hd76rx93b84 3 6 , , PUNCT hd76rx93b84 3 7 cpd cpd PROPN hd76rx93b84 3 8 and and CCONJ hd76rx93b84 3 9 pp pp NOUN hd76rx93b84 3 10 are be AUX hd76rx93b84 3 11 repaired repair VERB hd76rx93b84 3 12 via via ADP hd76rx93b84 3 13 cpd cpd PROPN hd76rx93b84 3 14 photolyase photolyase PROPN hd76rx93b84 3 15 and and CCONJ hd76rx93b84 3 16 ( ( PUNCT hd76rx93b84 3 17 6 6 NUM hd76rx93b84 3 18 - - SYM hd76rx93b84 3 19 4 4 NUM hd76rx93b84 3 20 ) ) PUNCT hd76rx93b84 3 21 photolyase photolyase NOUN hd76rx93b84 3 22 . . PUNCT hd76rx93b84 4 1 sparse sparse ADJ hd76rx93b84 4 2 experimental experimental ADJ hd76rx93b84 4 3 results result NOUN hd76rx93b84 4 4 support support VERB hd76rx93b84 4 5 a a DET hd76rx93b84 4 6 repair repair NOUN hd76rx93b84 4 7 mechanism mechanism NOUN hd76rx93b84 4 8 involving involve VERB hd76rx93b84 4 9 a a DET hd76rx93b84 4 10 light light NOUN hd76rx93b84 4 11 - - PUNCT hd76rx93b84 4 12 induced induce VERB hd76rx93b84 4 13 electron electron NOUN hd76rx93b84 4 14 - - PUNCT hd76rx93b84 4 15 transfer transfer NOUN hd76rx93b84 4 16 . . PUNCT hd76rx93b84 5 1 in in ADP hd76rx93b84 5 2 absence absence NOUN hd76rx93b84 5 3 of of ADP hd76rx93b84 5 4 an an DET hd76rx93b84 5 5 x x NOUN hd76rx93b84 5 6 - - NOUN hd76rx93b84 5 7 ray ray NOUN hd76rx93b84 5 8 structure structure NOUN hd76rx93b84 5 9 of of ADP hd76rx93b84 5 10 ( ( PUNCT hd76rx93b84 5 11 6 6 NUM hd76rx93b84 5 12 - - SYM hd76rx93b84 5 13 4 4 NUM hd76rx93b84 5 14 ) ) PUNCT hd76rx93b84 5 15 photolyase photolyase NOUN hd76rx93b84 5 16 and and CCONJ hd76rx93b84 5 17 due due ADP hd76rx93b84 5 18 to to ADP hd76rx93b84 5 19 the the DET hd76rx93b84 5 20 instability instability NOUN hd76rx93b84 5 21 of of ADP hd76rx93b84 5 22 the the DET hd76rx93b84 5 23 proposed propose VERB hd76rx93b84 5 24 oxetane oxetane NOUN hd76rx93b84 5 25 intermediate intermediate ADJ hd76rx93b84 5 26 the the DET hd76rx93b84 5 27 previously previously ADV hd76rx93b84 5 28 proposed propose VERB hd76rx93b84 5 29 oxetane oxetane NOUN hd76rx93b84 5 30 mechanism mechanism NOUN hd76rx93b84 5 31 can can AUX hd76rx93b84 5 32 not not PART hd76rx93b84 5 33 be be AUX hd76rx93b84 5 34 confirmed confirm VERB hd76rx93b84 5 35 experimentally experimentally ADV hd76rx93b84 5 36 . . PUNCT hd76rx93b84 6 1 mapping mapping NOUN hd76rx93b84 6 2 of of ADP hd76rx93b84 6 3 the the DET hd76rx93b84 6 4 potential potential ADJ hd76rx93b84 6 5 energy energy NOUN hd76rx93b84 6 6 surface surface NOUN hd76rx93b84 6 7 indicates indicate VERB hd76rx93b84 6 8 a a DET hd76rx93b84 6 9 barrierless barrierless NOUN hd76rx93b84 6 10 reaction reaction NOUN hd76rx93b84 6 11 from from ADP hd76rx93b84 6 12 the the DET hd76rx93b84 6 13 oxetane oxetane NOUN hd76rx93b84 6 14 radical radical ADJ hd76rx93b84 6 15 anion anion NOUN hd76rx93b84 6 16 to to ADP hd76rx93b84 6 17 two two NUM hd76rx93b84 6 18 thymine thymine NOUN hd76rx93b84 6 19 monmers monmer NOUN hd76rx93b84 6 20 . . PUNCT hd76rx93b84 7 1 formation formation NOUN hd76rx93b84 7 2 of of ADP hd76rx93b84 7 3 the the DET hd76rx93b84 7 4 oxetane oxetane NOUN hd76rx93b84 7 5 intermediate intermediate ADJ hd76rx93b84 7 6 from from ADP hd76rx93b84 7 7 two two NUM hd76rx93b84 7 8 thymines thymine NOUN hd76rx93b84 7 9 is be AUX hd76rx93b84 7 10 shown show VERB hd76rx93b84 7 11 to to PART hd76rx93b84 7 12 be be AUX hd76rx93b84 7 13 energetically energetically ADV hd76rx93b84 7 14 unfavorable unfavorable ADJ hd76rx93b84 7 15 . . PUNCT hd76rx93b84 8 1 reduction reduction NOUN hd76rx93b84 8 2 of of ADP hd76rx93b84 8 3 the the DET hd76rx93b84 8 4 oxetane oxetane NOUN hd76rx93b84 8 5 is be AUX hd76rx93b84 8 6 also also ADV hd76rx93b84 8 7 shown show VERB hd76rx93b84 8 8 to to PART hd76rx93b84 8 9 be be AUX hd76rx93b84 8 10 more more ADV hd76rx93b84 8 11 energetically energetically ADV hd76rx93b84 8 12 unfavorable unfavorable ADJ hd76rx93b84 8 13 that that SCONJ hd76rx93b84 8 14 direct direct ADJ hd76rx93b84 8 15 reduction reduction NOUN hd76rx93b84 8 16 of of ADP hd76rx93b84 8 17 pp pp PROPN hd76rx93b84 8 18 . . PUNCT hd76rx93b84 9 1 ab ab PROPN hd76rx93b84 9 2 inito inito PROPN hd76rx93b84 9 3 gas gas NOUN hd76rx93b84 9 4 phase phase NOUN hd76rx93b84 9 5 and and CCONJ hd76rx93b84 9 6 solution solution NOUN hd76rx93b84 9 7 calculations calculation NOUN hd76rx93b84 9 8 using use VERB hd76rx93b84 9 9 theozyme theozyme NOUN hd76rx93b84 9 10 models model NOUN hd76rx93b84 9 11 were be AUX hd76rx93b84 9 12 used use VERB hd76rx93b84 9 13 to to PART hd76rx93b84 9 14 systematically systematically ADV hd76rx93b84 9 15 reduce reduce VERB hd76rx93b84 9 16 alternative alternative ADJ hd76rx93b84 9 17 mechanistic mechanistic ADJ hd76rx93b84 9 18 possibilities possibility NOUN hd76rx93b84 9 19 to to ADP hd76rx93b84 9 20 two two NUM hd76rx93b84 9 21 competing compete VERB hd76rx93b84 9 22 pathways pathway NOUN hd76rx93b84 9 23 : : PUNCT hd76rx93b84 9 24 the the DET hd76rx93b84 9 25 oxetane oxetane NOUN hd76rx93b84 9 26 and and CCONJ hd76rx93b84 9 27 the the DET hd76rx93b84 9 28 carbinolamine carbinolamine NOUN hd76rx93b84 9 29 mechanisms mechanism NOUN hd76rx93b84 9 30 . . PUNCT hd76rx93b84 10 1 repair repair NOUN hd76rx93b84 10 2 of of ADP hd76rx93b84 10 3 pp pp PROPN hd76rx93b84 10 4 via via ADP hd76rx93b84 10 5 the the DET hd76rx93b84 10 6 carbinolamine carbinolamine NOUN hd76rx93b84 10 7 mechanism mechanism NOUN hd76rx93b84 10 8 was be AUX hd76rx93b84 10 9 found find VERB hd76rx93b84 10 10 to to PART hd76rx93b84 10 11 be be AUX hd76rx93b84 10 12 the the DET hd76rx93b84 10 13 energetically energetically ADV hd76rx93b84 10 14 preferred preferred ADJ hd76rx93b84 10 15 mechanism mechanism NOUN hd76rx93b84 10 16 . . PUNCT hd76rx93b84 11 1 additionally additionally ADV hd76rx93b84 11 2 , , PUNCT hd76rx93b84 11 3 repair repair NOUN hd76rx93b84 11 4 of of ADP hd76rx93b84 11 5 the the DET hd76rx93b84 11 6 minor minor ADJ hd76rx93b84 11 7 dewar dewar ADJ hd76rx93b84 11 8 photoproduct photoproduct NOUN hd76rx93b84 11 9 , , PUNCT hd76rx93b84 11 10 by by ADP hd76rx93b84 11 11 ( ( PUNCT hd76rx93b84 11 12 6 6 NUM hd76rx93b84 11 13 - - SYM hd76rx93b84 11 14 4 4 NUM hd76rx93b84 11 15 ) ) PUNCT hd76rx93b84 11 16 photolyase photolyase NOUN hd76rx93b84 11 17 is be AUX hd76rx93b84 11 18 explained explain VERB hd76rx93b84 11 19 by by ADP hd76rx93b84 11 20 merging merge VERB hd76rx93b84 11 21 the the DET hd76rx93b84 11 22 dewar dewar ADJ hd76rx93b84 11 23 repair repair NOUN hd76rx93b84 11 24 mechanism mechanism NOUN hd76rx93b84 11 25 with with ADP hd76rx93b84 11 26 that that PRON hd76rx93b84 11 27 of of ADP hd76rx93b84 11 28 the the DET hd76rx93b84 11 29 carbinolamine carbinolamine NOUN hd76rx93b84 11 30 mechanism mechanism NOUN hd76rx93b84 11 31 . . PUNCT hd76rx93b84 12 1 docking docking NOUN hd76rx93b84 12 2 and and CCONJ hd76rx93b84 12 3 molecular molecular ADJ hd76rx93b84 12 4 dynamics dynamic NOUN hd76rx93b84 12 5 of of ADP hd76rx93b84 12 6 pp pp PROPN hd76rx93b84 12 7 or or CCONJ hd76rx93b84 12 8 the the DET hd76rx93b84 12 9 oxetane oxetane NOUN hd76rx93b84 12 10 intermediate intermediate ADJ hd76rx93b84 12 11 in in ADP hd76rx93b84 12 12 a a DET hd76rx93b84 12 13 refined refined ADJ hd76rx93b84 12 14 homology homology NOUN hd76rx93b84 12 15 model model NOUN hd76rx93b84 12 16 of of ADP hd76rx93b84 12 17 ( ( PUNCT hd76rx93b84 12 18 6 6 NUM hd76rx93b84 12 19 - - SYM hd76rx93b84 12 20 4 4 NUM hd76rx93b84 12 21 ) ) PUNCT hd76rx93b84 12 22 photolyase photolyase NOUN hd76rx93b84 12 23 provided provide VERB hd76rx93b84 12 24 structural structural ADJ hd76rx93b84 12 25 models model NOUN hd76rx93b84 12 26 of of ADP hd76rx93b84 12 27 the the DET hd76rx93b84 12 28 enzyme enzyme NOUN hd76rx93b84 12 29 - - PUNCT hd76rx93b84 12 30 substrate substrate NOUN hd76rx93b84 12 31 complexes complex NOUN hd76rx93b84 12 32 and and CCONJ hd76rx93b84 12 33 were be AUX hd76rx93b84 12 34 found find VERB hd76rx93b84 12 35 to to PART hd76rx93b84 12 36 be be AUX hd76rx93b84 12 37 consistent consistent ADJ hd76rx93b84 12 38 with with ADP hd76rx93b84 12 39 a a DET hd76rx93b84 12 40 carbinolamine carbinolamine NOUN hd76rx93b84 12 41 mechanism mechanism NOUN hd76rx93b84 12 42 . . PUNCT hd76rx93b84 13 1 more more ADV hd76rx93b84 13 2 comprehensive comprehensive ADJ hd76rx93b84 13 3 simulations simulation NOUN hd76rx93b84 13 4 included include VERB hd76rx93b84 13 5 a a DET hd76rx93b84 13 6 short short ADJ hd76rx93b84 13 7 ddna ddna PROPN hd76rx93b84 13 8 fragment fragment NOUN hd76rx93b84 13 9 containing contain VERB hd76rx93b84 13 10 pp pp PROPN hd76rx93b84 13 11 bound bind VERB hd76rx93b84 13 12 in in ADP hd76rx93b84 13 13 the the DET hd76rx93b84 13 14 active active ADJ hd76rx93b84 13 15 site site NOUN hd76rx93b84 13 16 of of ADP hd76rx93b84 13 17 ( ( PUNCT hd76rx93b84 13 18 6 6 NUM hd76rx93b84 13 19 - - SYM hd76rx93b84 13 20 4 4 NUM hd76rx93b84 13 21 ) ) PUNCT hd76rx93b84 13 22 photolyase photolyase NOUN hd76rx93b84 13 23 . . PUNCT hd76rx93b84 14 1 molecular molecular ADJ hd76rx93b84 14 2 dynamics dynamic NOUN hd76rx93b84 14 3 results result NOUN hd76rx93b84 14 4 described describe VERB hd76rx93b84 14 5 key key ADJ hd76rx93b84 14 6 residue residue ADJ hd76rx93b84 14 7 interactions interaction NOUN hd76rx93b84 14 8 involved involve VERB hd76rx93b84 14 9 in in ADP hd76rx93b84 14 10 mechanistic mechanistic ADJ hd76rx93b84 14 11 and and CCONJ hd76rx93b84 14 12 binding binding ADJ hd76rx93b84 14 13 interactions interaction NOUN hd76rx93b84 14 14 between between ADP hd76rx93b84 14 15 ( ( PUNCT hd76rx93b84 14 16 6 6 NUM hd76rx93b84 14 17 - - SYM hd76rx93b84 14 18 4 4 NUM hd76rx93b84 14 19 ) ) PUNCT hd76rx93b84 14 20 photolyase photolyase NOUN hd76rx93b84 14 21 , , PUNCT hd76rx93b84 14 22 fadh fadh NOUN hd76rx93b84 14 23 and and CCONJ hd76rx93b84 14 24 pp pp PROPN hd76rx93b84 14 25 . . PUNCT hd76rx93b84 15 1 the the DET hd76rx93b84 15 2 experimental experimental ADJ hd76rx93b84 15 3 component component NOUN hd76rx93b84 15 4 of of ADP hd76rx93b84 15 5 this this DET hd76rx93b84 15 6 work work NOUN hd76rx93b84 15 7 involved involve VERB hd76rx93b84 15 8 design design NOUN hd76rx93b84 15 9 of of ADP hd76rx93b84 15 10 a a DET hd76rx93b84 15 11 reductive reductive ADJ hd76rx93b84 15 12 , , PUNCT hd76rx93b84 15 13 biomimetic biomimetic ADJ hd76rx93b84 15 14 , , PUNCT hd76rx93b84 15 15 artificial artificial ADJ hd76rx93b84 15 16 photolyase photolyase NOUN hd76rx93b84 15 17 capable capable ADJ hd76rx93b84 15 18 of of ADP hd76rx93b84 15 19 selective selective ADJ hd76rx93b84 15 20 noncovalent noncovalent NOUN hd76rx93b84 15 21 binding binding NOUN hd76rx93b84 15 22 and and CCONJ hd76rx93b84 15 23 repair repair NOUN hd76rx93b84 15 24 of of ADP hd76rx93b84 15 25 cpd cpd PROPN hd76rx93b84 15 26 in in ADP hd76rx93b84 15 27 water water NOUN hd76rx93b84 15 28 . . PUNCT hd76rx93b84 16 1 after after ADP hd76rx93b84 16 2 successfully successfully ADV hd76rx93b84 16 3 demonstrating demonstrate VERB hd76rx93b84 16 4 the the DET hd76rx93b84 16 5 function function NOUN hd76rx93b84 16 6 of of ADP hd76rx93b84 16 7 the the DET hd76rx93b84 16 8 ar ar PROPN hd76rx93b84 16 9 tificial tificial PROPN hd76rx93b84 16 10 photolyase photolyase NOUN hd76rx93b84 16 11 in in ADP hd76rx93b84 16 12 the the DET hd76rx93b84 16 13 repair repair NOUN hd76rx93b84 16 14 of of ADP hd76rx93b84 16 15 cpd cpd NOUN hd76rx93b84 16 16 models model NOUN hd76rx93b84 16 17 under under ADP hd76rx93b84 16 18 physiological physiological ADJ hd76rx93b84 16 19 conditions condition NOUN hd76rx93b84 16 20 , , PUNCT hd76rx93b84 16 21 the the DET hd76rx93b84 16 22 reductive reductive ADJ hd76rx93b84 16 23 artificial artificial ADJ hd76rx93b84 16 24 photolyase photolyase NOUN hd76rx93b84 16 25 was be AUX hd76rx93b84 16 26 shown show VERB hd76rx93b84 16 27 to to PART hd76rx93b84 16 28 successfully successfully ADV hd76rx93b84 16 29 repair repair VERB hd76rx93b84 16 30 cpd cpd NOUN hd76rx93b84 16 31 with with ADP hd76rx93b84 16 32 a a DET hd76rx93b84 16 33 phosphate phosphate NOUN hd76rx93b84 16 34 backbone backbone NOUN hd76rx93b84 16 35 under under ADP hd76rx93b84 16 36 physiological physiological ADJ hd76rx93b84 16 37 conditions condition NOUN hd76rx93b84 16 38 . . PUNCT hd76rx93b84 17 1 the the DET hd76rx93b84 17 2 development development NOUN hd76rx93b84 17 3 of of ADP hd76rx93b84 17 4 an an DET hd76rx93b84 17 5 assay assay NOUN hd76rx93b84 17 6 capable capable ADJ hd76rx93b84 17 7 of of ADP hd76rx93b84 17 8 separating separate VERB hd76rx93b84 17 9 and and CCONJ hd76rx93b84 17 10 quantitatively quantitatively ADV hd76rx93b84 17 11 measuring measure VERB hd76rx93b84 17 12 the the DET hd76rx93b84 17 13 photo photo NOUN hd76rx93b84 17 14 - - PUNCT hd76rx93b84 17 15 reaction reaction NOUN hd76rx93b84 17 16 kinetics kinetic NOUN hd76rx93b84 17 17 cpd cpd PROPN hd76rx93b84 17 18 repair repair PROPN hd76rx93b84 17 19 in in ADP hd76rx93b84 17 20 ddna ddna PROPN hd76rx93b84 17 21 was be AUX hd76rx93b84 17 22 completed complete VERB hd76rx93b84 17 23 . . PUNCT