id sid tid token lemma pos h702q527w9h 1 1 accumulating accumulate VERB h702q527w9h 1 2 evidence evidence NOUN h702q527w9h 1 3 has have AUX h702q527w9h 1 4 shown show VERB h702q527w9h 1 5 the the DET h702q527w9h 1 6 presence presence NOUN h702q527w9h 1 7 of of ADP h702q527w9h 1 8 embryonic embryonic ADJ h702q527w9h 1 9 stem stem NOUN h702q527w9h 1 10 cell cell NOUN h702q527w9h 1 11 programs program NOUN h702q527w9h 1 12 in in ADP h702q527w9h 1 13 cancer cancer NOUN h702q527w9h 1 14 cells cell NOUN h702q527w9h 1 15 that that PRON h702q527w9h 1 16 contribute contribute VERB h702q527w9h 1 17 to to ADP h702q527w9h 1 18 aggressive aggressive ADJ h702q527w9h 1 19 malignancy malignancy NOUN h702q527w9h 1 20 . . PUNCT h702q527w9h 2 1 to to PART h702q527w9h 2 2 strategically strategically ADV h702q527w9h 2 3 identify identify VERB h702q527w9h 2 4 relevant relevant ADJ h702q527w9h 2 5 embryonic embryonic ADJ h702q527w9h 2 6 - - PUNCT h702q527w9h 2 7 like like ADJ h702q527w9h 2 8 mechanisms mechanism NOUN h702q527w9h 2 9 exploited exploit VERB h702q527w9h 2 10 by by ADP h702q527w9h 2 11 cancer cancer NOUN h702q527w9h 2 12 cells cell NOUN h702q527w9h 2 13 , , PUNCT h702q527w9h 2 14 we we PRON h702q527w9h 2 15 performed perform VERB h702q527w9h 2 16 mass mass ADJ h702q527w9h 2 17 spectrometry spectrometry NOUN h702q527w9h 2 18 of of ADP h702q527w9h 2 19 the the DET h702q527w9h 2 20 cell cell NOUN h702q527w9h 2 21 surface surface NOUN h702q527w9h 2 22 proteome proteome NOUN h702q527w9h 2 23 of of ADP h702q527w9h 2 24 human human ADJ h702q527w9h 2 25 induced induce VERB h702q527w9h 2 26 pluripotent pluripotent ADJ h702q527w9h 2 27 stem stem NOUN h702q527w9h 2 28 cells cell NOUN h702q527w9h 2 29 ( ( PUNCT h702q527w9h 2 30 ips ips PROPN h702q527w9h 2 31 cells cell NOUN h702q527w9h 2 32 ) ) PUNCT h702q527w9h 2 33 and and CCONJ h702q527w9h 2 34 breast breast NOUN h702q527w9h 2 35 cancer cancer NOUN h702q527w9h 2 36 cells cell NOUN h702q527w9h 2 37 to to PART h702q527w9h 2 38 find find VERB h702q527w9h 2 39 surface surface NOUN h702q527w9h 2 40 molecules molecule NOUN h702q527w9h 2 41 shared share VERB h702q527w9h 2 42 by by ADP h702q527w9h 2 43 both both DET h702q527w9h 2 44 cell cell NOUN h702q527w9h 2 45 types type NOUN h702q527w9h 2 46 . . PUNCT h702q527w9h 3 1 plakoglobin plakoglobin PROPN h702q527w9h 3 2 was be AUX h702q527w9h 3 3 identified identify VERB h702q527w9h 3 4 as as ADP h702q527w9h 3 5 a a DET h702q527w9h 3 6 target target NOUN h702q527w9h 3 7 of of ADP h702q527w9h 3 8 high high ADJ h702q527w9h 3 9 significance significance NOUN h702q527w9h 3 10 for for ADP h702q527w9h 3 11 its its PRON h702q527w9h 3 12 reported reported ADJ h702q527w9h 3 13 importance importance NOUN h702q527w9h 3 14 in in ADP h702q527w9h 3 15 circulating circulate VERB h702q527w9h 3 16 tumor tumor NOUN h702q527w9h 3 17 cell cell NOUN h702q527w9h 3 18 ( ( PUNCT h702q527w9h 3 19 ctc ctc NOUN h702q527w9h 3 20 ) ) PUNCT h702q527w9h 3 21 clusters cluster NOUN h702q527w9h 3 22 of of ADP h702q527w9h 3 23 breast breast NOUN h702q527w9h 3 24 cancer cancer NOUN h702q527w9h 3 25 . . PUNCT h702q527w9h 4 1 moreover moreover ADV h702q527w9h 4 2 , , PUNCT h702q527w9h 4 3 as as ADP h702q527w9h 4 4 a a DET h702q527w9h 4 5 homolog homolog NOUN h702q527w9h 4 6 of of ADP h702q527w9h 4 7 β β PROPN h702q527w9h 4 8 - - PUNCT h702q527w9h 4 9 catenin catenin PROPN h702q527w9h 4 10 , , PUNCT h702q527w9h 4 11 plakoglobin plakoglobin PROPN h702q527w9h 4 12 has have AUX h702q527w9h 4 13 also also ADV h702q527w9h 4 14 been be AUX h702q527w9h 4 15 described describe VERB h702q527w9h 4 16 to to PART h702q527w9h 4 17 be be AUX h702q527w9h 4 18 involved involve VERB h702q527w9h 4 19 in in ADP h702q527w9h 4 20 signaling signal VERB h702q527w9h 4 21 pathways pathway NOUN h702q527w9h 4 22 essential essential ADJ h702q527w9h 4 23 for for ADP h702q527w9h 4 24 both both DET h702q527w9h 4 25 cancer cancer NOUN h702q527w9h 4 26 cells cell NOUN h702q527w9h 4 27 and and CCONJ h702q527w9h 4 28 stem stem NOUN h702q527w9h 4 29 cells cell NOUN h702q527w9h 4 30 . . PUNCT h702q527w9h 5 1 however however ADV h702q527w9h 5 2 , , PUNCT h702q527w9h 5 3 how how SCONJ h702q527w9h 5 4 plakoglobin plakoglobin PROPN h702q527w9h 5 5 affects affect VERB h702q527w9h 5 6 cancer cancer NOUN h702q527w9h 5 7 aggressiveness aggressiveness NOUN h702q527w9h 5 8 , , PUNCT h702q527w9h 5 9 and and CCONJ h702q527w9h 5 10 whether whether SCONJ h702q527w9h 5 11 it it PRON h702q527w9h 5 12 plays play VERB h702q527w9h 5 13 an an DET h702q527w9h 5 14 important important ADJ h702q527w9h 5 15 role role NOUN h702q527w9h 5 16 in in ADP h702q527w9h 5 17 maintaining maintain VERB h702q527w9h 5 18 stem stem NOUN h702q527w9h 5 19 cell cell NOUN h702q527w9h 5 20 functions function NOUN h702q527w9h 5 21 , , PUNCT h702q527w9h 5 22 remains remain VERB h702q527w9h 5 23 unclear unclear ADJ h702q527w9h 5 24 . . PUNCT h702q527w9h 6 1 here here ADV h702q527w9h 6 2 , , PUNCT h702q527w9h 6 3 we we PRON h702q527w9h 6 4 report report VERB h702q527w9h 6 5 that that SCONJ h702q527w9h 6 6 plakoglobin plakoglobin NOUN h702q527w9h 6 7 is be AUX h702q527w9h 6 8 overexpressed overexpresse VERB h702q527w9h 6 9 in in ADP h702q527w9h 6 10 cancer cancer NOUN h702q527w9h 6 11 stem stem NOUN h702q527w9h 6 12 cell cell NOUN h702q527w9h 6 13 populations population NOUN h702q527w9h 6 14 of of ADP h702q527w9h 6 15 breast breast NOUN h702q527w9h 6 16 cancer cancer NOUN h702q527w9h 6 17 , , PUNCT h702q527w9h 6 18 as as ADV h702q527w9h 6 19 well well ADV h702q527w9h 6 20 as as ADP h702q527w9h 6 21 ips ips PROPN h702q527w9h 6 22 cells cell NOUN h702q527w9h 6 23 compared compare VERB h702q527w9h 6 24 to to ADP h702q527w9h 6 25 their their PRON h702q527w9h 6 26 parental parental ADJ h702q527w9h 6 27 somatic somatic ADJ h702q527w9h 6 28 cells cell NOUN h702q527w9h 6 29 . . PUNCT h702q527w9h 7 1 overexpression overexpression NOUN h702q527w9h 7 2 of of ADP h702q527w9h 7 3 plakoglobin plakoglobin PROPN h702q527w9h 7 4 resulted result VERB h702q527w9h 7 5 in in ADP h702q527w9h 7 6 elevated elevated ADJ h702q527w9h 7 7 cell cell NOUN h702q527w9h 7 8 - - PUNCT h702q527w9h 7 9 cell cell NOUN h702q527w9h 7 10 adhesion adhesion NOUN h702q527w9h 7 11 , , PUNCT h702q527w9h 7 12 as as ADV h702q527w9h 7 13 well well ADV h702q527w9h 7 14 as as ADP h702q527w9h 7 15 motility motility NOUN h702q527w9h 7 16 , , PUNCT h702q527w9h 7 17 in in ADP h702q527w9h 7 18 both both PRON h702q527w9h 7 19 breast breast NOUN h702q527w9h 7 20 cancer cancer NOUN h702q527w9h 7 21 cells cell NOUN h702q527w9h 7 22 and and CCONJ h702q527w9h 7 23 ips ips PROPN h702q527w9h 7 24 cells cell NOUN h702q527w9h 7 25 . . PUNCT h702q527w9h 8 1 furthermore furthermore ADV h702q527w9h 8 2 , , PUNCT h702q527w9h 8 3 overexpression overexpression NOUN h702q527w9h 8 4 of of ADP h702q527w9h 8 5 plakoglobin plakoglobin NOUN h702q527w9h 8 6 in in ADP h702q527w9h 8 7 both both DET h702q527w9h 8 8 cell cell NOUN h702q527w9h 8 9 types type NOUN h702q527w9h 8 10 led lead VERB h702q527w9h 8 11 to to ADP h702q527w9h 8 12 increased increase VERB h702q527w9h 8 13 resistance resistance NOUN h702q527w9h 8 14 to to ADP h702q527w9h 8 15 apoptosis apoptosis NOUN h702q527w9h 8 16 by by ADP h702q527w9h 8 17 alleviating alleviate VERB h702q527w9h 8 18 rho rho NOUN h702q527w9h 8 19 / / SYM h702q527w9h 8 20 rock rock NOUN h702q527w9h 8 21 activity activity NOUN h702q527w9h 8 22 through through ADP h702q527w9h 8 23 increased increase VERB h702q527w9h 8 24 cell cell NOUN h702q527w9h 8 25 adhesion adhesion NOUN h702q527w9h 8 26 . . PUNCT h702q527w9h 9 1 our our PRON h702q527w9h 9 2 findings finding NOUN h702q527w9h 9 3 establish establish VERB h702q527w9h 9 4 a a DET h702q527w9h 9 5 novel novel ADJ h702q527w9h 9 6 role role NOUN h702q527w9h 9 7 for for ADP h702q527w9h 9 8 plakoglobin plakoglobin NOUN h702q527w9h 9 9 in in ADP h702q527w9h 9 10 regulating regulate VERB h702q527w9h 9 11 cell cell NOUN h702q527w9h 9 12 behavior behavior NOUN h702q527w9h 9 13 and and CCONJ h702q527w9h 9 14 survival survival NOUN h702q527w9h 9 15 in in ADP h702q527w9h 9 16 cancer cancer NOUN h702q527w9h 9 17 and and CCONJ h702q527w9h 9 18 stem stem NOUN h702q527w9h 9 19 cells cell NOUN h702q527w9h 9 20 , , PUNCT h702q527w9h 9 21 and and CCONJ h702q527w9h 9 22 suggest suggest VERB h702q527w9h 9 23 that that SCONJ h702q527w9h 9 24 an an DET h702q527w9h 9 25 embryonic embryonic ADJ h702q527w9h 9 26 - - PUNCT h702q527w9h 9 27 like like ADJ h702q527w9h 9 28 mechanism mechanism NOUN h702q527w9h 9 29 of of ADP h702q527w9h 9 30 plakoglobin plakoglobin PROPN h702q527w9h 9 31 may may AUX h702q527w9h 9 32 be be AUX h702q527w9h 9 33 exploited exploit VERB h702q527w9h 9 34 by by ADP h702q527w9h 9 35 cancer cancer NOUN h702q527w9h 9 36 cells cell NOUN h702q527w9h 9 37 to to PART h702q527w9h 9 38 provide provide VERB h702q527w9h 9 39 a a DET h702q527w9h 9 40 survival survival NOUN h702q527w9h 9 41 advantage advantage NOUN h702q527w9h 9 42 to to PART h702q527w9h 9 43 overcome overcome VERB h702q527w9h 9 44 anoikis anoiki NOUN h702q527w9h 9 45 during during ADP h702q527w9h 9 46 metastasis metastasis NOUN h702q527w9h 9 47 . . PUNCT h702q527w9h 10 1 the the DET h702q527w9h 10 2 paralleled parallel VERB h702q527w9h 10 3 studies study NOUN h702q527w9h 10 4 in in ADP h702q527w9h 10 5 ips ips PROPN h702q527w9h 10 6 cells cell NOUN h702q527w9h 10 7 provide provide VERB h702q527w9h 10 8 insights insight NOUN h702q527w9h 10 9 into into ADP h702q527w9h 10 10 future future ADJ h702q527w9h 10 11 mechanistic mechanistic ADJ h702q527w9h 10 12 inquiries inquiry NOUN h702q527w9h 10 13 of of ADP h702q527w9h 10 14 tumor tumor NOUN h702q527w9h 10 15 progression progression NOUN h702q527w9h 10 16 , , PUNCT h702q527w9h 10 17 and and CCONJ h702q527w9h 10 18 thus thus ADV h702q527w9h 10 19 new new ADJ h702q527w9h 10 20 potential potential ADJ h702q527w9h 10 21 avenues avenue NOUN h702q527w9h 10 22 for for ADP h702q527w9h 10 23 therapeutic therapeutic ADJ h702q527w9h 10 24 target target NOUN h702q527w9h 10 25 discoveries discovery NOUN h702q527w9h 10 26 towards towards ADP h702q527w9h 10 27 the the DET h702q527w9h 10 28 long long ADJ h702q527w9h 10 29 - - PUNCT h702q527w9h 10 30 term term NOUN h702q527w9h 10 31 goals goal NOUN h702q527w9h 10 32 of of ADP h702q527w9h 10 33 preventing prevent VERB h702q527w9h 10 34 cancer cancer NOUN h702q527w9h 10 35 metastasis metastasis NOUN h702q527w9h 10 36 and and CCONJ h702q527w9h 10 37 relapse relapse NOUN h702q527w9h 10 38 . . PUNCT