id	sid	tid	token	lemma	pos
gm80ht27s0n	1	1	pancreatic	pancreatic	ADJ
gm80ht27s0n	1	2	ductal	ductal	NOUN
gm80ht27s0n	1	3	adenocarcinoma	adenocarcinoma	NOUN
gm80ht27s0n	1	4	(	(	PUNCT
gm80ht27s0n	1	5	pdac	pdac	PROPN
gm80ht27s0n	1	6	)	)	PUNCT
gm80ht27s0n	1	7	is	be	AUX
gm80ht27s0n	1	8	the	the	DET
gm80ht27s0n	1	9	3rd	3rd	ADJ
gm80ht27s0n	1	10	leading	leading	ADJ
gm80ht27s0n	1	11	cause	cause	NOUN
gm80ht27s0n	1	12	of	of	ADP
gm80ht27s0n	1	13	cancer	cancer	NOUN
gm80ht27s0n	1	14	related	relate	VERB
gm80ht27s0n	1	15	death	death	NOUN
gm80ht27s0n	1	16	and	and	CCONJ
gm80ht27s0n	1	17	has	have	VERB
gm80ht27s0n	1	18	a	a	DET
gm80ht27s0n	1	19	five	five	NUM
gm80ht27s0n	1	20	year	year	NOUN
gm80ht27s0n	1	21	survival	survival	NOUN
gm80ht27s0n	1	22	rate	rate	NOUN
gm80ht27s0n	1	23	below	below	ADP
gm80ht27s0n	1	24	8	8	NUM
gm80ht27s0n	1	25	%	%	NOUN
gm80ht27s0n	1	26	.	.	PUNCT
gm80ht27s0n	2	1	this	this	DET
gm80ht27s0n	2	2	poor	poor	ADJ
gm80ht27s0n	2	3	prognosis	prognosis	NOUN
gm80ht27s0n	2	4	is	be	AUX
gm80ht27s0n	2	5	largely	largely	ADV
gm80ht27s0n	2	6	attributed	attribute	VERB
gm80ht27s0n	2	7	to	to	ADP
gm80ht27s0n	2	8	late	late	ADJ
gm80ht27s0n	2	9	diagnosis	diagnosis	NOUN
gm80ht27s0n	2	10	,	,	PUNCT
gm80ht27s0n	2	11	which	which	PRON
gm80ht27s0n	2	12	leaves	leave	VERB
gm80ht27s0n	2	13	clinicians	clinician	NOUN
gm80ht27s0n	2	14	to	to	PART
gm80ht27s0n	2	15	treat	treat	VERB
gm80ht27s0n	2	16	an	an	DET
gm80ht27s0n	2	17	advanced	advanced	ADJ
gm80ht27s0n	2	18	,	,	PUNCT
gm80ht27s0n	2	19	chemoresistant	chemoresistant	ADJ
gm80ht27s0n	2	20	disease	disease	NOUN
gm80ht27s0n	2	21	.	.	PUNCT
gm80ht27s0n	3	1	gemcitabine	gemcitabine	NOUN
gm80ht27s0n	3	2	based	base	VERB
gm80ht27s0n	3	3	therapy	therapy	NOUN
gm80ht27s0n	3	4	is	be	AUX
gm80ht27s0n	3	5	the	the	DET
gm80ht27s0n	3	6	standard	standard	NOUN
gm80ht27s0n	3	7	of	of	ADP
gm80ht27s0n	3	8	care	care	NOUN
gm80ht27s0n	3	9	for	for	ADP
gm80ht27s0n	3	10	patients	patient	NOUN
gm80ht27s0n	3	11	;	;	PUNCT
gm80ht27s0n	3	12	however	however	ADV
gm80ht27s0n	3	13	,	,	PUNCT
gm80ht27s0n	3	14	in	in	ADP
gm80ht27s0n	3	15	the	the	DET
gm80ht27s0n	3	16	majority	majority	NOUN
gm80ht27s0n	3	17	of	of	ADP
gm80ht27s0n	3	18	cases	case	NOUN
gm80ht27s0n	3	19	,	,	PUNCT
gm80ht27s0n	3	20	patients	patient	NOUN
gm80ht27s0n	3	21	exhibit	exhibit	VERB
gm80ht27s0n	3	22	tumor	tumor	NOUN
gm80ht27s0n	3	23	relapse	relapse	NOUN
gm80ht27s0n	3	24	and	and	CCONJ
gm80ht27s0n	3	25	resistance	resistance	NOUN
gm80ht27s0n	3	26	.	.	PUNCT
gm80ht27s0n	4	1	the	the	DET
gm80ht27s0n	4	2	overall	overall	ADJ
gm80ht27s0n	4	3	goal	goal	NOUN
gm80ht27s0n	4	4	of	of	ADP
gm80ht27s0n	4	5	this	this	DET
gm80ht27s0n	4	6	research	research	NOUN
gm80ht27s0n	4	7	was	be	AUX
gm80ht27s0n	4	8	to	to	PART
gm80ht27s0n	4	9	identify	identify	VERB
gm80ht27s0n	4	10	a	a	DET
gm80ht27s0n	4	11	mechanism	mechanism	NOUN
gm80ht27s0n	4	12	of	of	ADP
gm80ht27s0n	4	13	chemoresistance	chemoresistance	NOUN
gm80ht27s0n	4	14	and	and	CCONJ
gm80ht27s0n	4	15	develop	develop	VERB
gm80ht27s0n	4	16	a	a	DET
gm80ht27s0n	4	17	strategy	strategy	NOUN
gm80ht27s0n	4	18	to	to	PART
gm80ht27s0n	4	19	exploit	exploit	VERB
gm80ht27s0n	4	20	it	it	PRON
gm80ht27s0n	4	21	,	,	PUNCT
gm80ht27s0n	4	22	in	in	ADP
gm80ht27s0n	4	23	order	order	NOUN
gm80ht27s0n	4	24	to	to	PART
gm80ht27s0n	4	25	improve	improve	VERB
gm80ht27s0n	4	26	the	the	DET
gm80ht27s0n	4	27	efficacy	efficacy	NOUN
gm80ht27s0n	4	28	of	of	ADP
gm80ht27s0n	4	29	gemcitabine	gemcitabine	NOUN
gm80ht27s0n	4	30	(	(	PUNCT
gm80ht27s0n	4	31	gem	gem	NOUN
gm80ht27s0n	4	32	)	)	PUNCT
gm80ht27s0n	4	33	.	.	PUNCT
gm80ht27s0n	5	1	it	it	PRON
gm80ht27s0n	5	2	was	be	AUX
gm80ht27s0n	5	3	established	establish	VERB
gm80ht27s0n	5	4	that	that	DET
gm80ht27s0n	5	5	induction	induction	NOUN
gm80ht27s0n	5	6	of	of	ADP
gm80ht27s0n	5	7	grp78	grp78	PROPN
gm80ht27s0n	5	8	,	,	PUNCT
gm80ht27s0n	5	9	an	an	DET
gm80ht27s0n	5	10	endoplasmic	endoplasmic	ADJ
gm80ht27s0n	5	11	reticulum	reticulum	NOUN
gm80ht27s0n	5	12	chaperone	chaperone	NOUN
gm80ht27s0n	5	13	protein	protein	NOUN
gm80ht27s0n	5	14	,	,	PUNCT
gm80ht27s0n	5	15	has	have	VERB
gm80ht27s0n	5	16	a	a	DET
gm80ht27s0n	5	17	direct	direct	ADJ
gm80ht27s0n	5	18	relationship	relationship	NOUN
gm80ht27s0n	5	19	with	with	ADP
gm80ht27s0n	5	20	the	the	DET
gm80ht27s0n	5	21	gem	gem	NOUN
gm80ht27s0n	5	22	-	-	PUNCT
gm80ht27s0n	5	23	resistant	resistant	ADJ
gm80ht27s0n	5	24	status	status	NOUN
gm80ht27s0n	5	25	of	of	ADP
gm80ht27s0n	5	26	pancreatic	pancreatic	ADJ
gm80ht27s0n	5	27	cancer	cancer	NOUN
gm80ht27s0n	5	28	cell	cell	NOUN
gm80ht27s0n	5	29	lines	line	NOUN
gm80ht27s0n	5	30	and	and	CCONJ
gm80ht27s0n	5	31	tumors	tumor	NOUN
gm80ht27s0n	5	32	.	.	PUNCT
gm80ht27s0n	6	1	furthermore	furthermore	ADV
gm80ht27s0n	6	2	,	,	PUNCT
gm80ht27s0n	6	3	it	it	PRON
gm80ht27s0n	6	4	was	be	AUX
gm80ht27s0n	6	5	found	find	VERB
gm80ht27s0n	6	6	that	that	SCONJ
gm80ht27s0n	6	7	grp78	grp78	PROPN
gm80ht27s0n	6	8	could	could	AUX
gm80ht27s0n	6	9	be	be	AUX
gm80ht27s0n	6	10	induced	induce	VERB
gm80ht27s0n	6	11	by	by	ADP
gm80ht27s0n	6	12	gem	gem	NOUN
gm80ht27s0n	6	13	,	,	PUNCT
gm80ht27s0n	6	14	itself	itself	PRON
gm80ht27s0n	6	15	,	,	PUNCT
gm80ht27s0n	6	16	potentially	potentially	ADV
gm80ht27s0n	6	17	inducing	induce	VERB
gm80ht27s0n	6	18	its	its	PRON
gm80ht27s0n	6	19	own	own	ADJ
gm80ht27s0n	6	20	resistance	resistance	NOUN
gm80ht27s0n	6	21	mechanism	mechanism	NOUN
gm80ht27s0n	6	22	.	.	PUNCT
gm80ht27s0n	7	1	sirna	sirna	PROPN
gm80ht27s0n	7	2	knockdown	knockdown	PROPN
gm80ht27s0n	7	3	of	of	ADP
gm80ht27s0n	7	4	grp78	grp78	ADJ
gm80ht27s0n	7	5	expression	expression	NOUN
gm80ht27s0n	7	6	was	be	AUX
gm80ht27s0n	7	7	able	able	ADJ
gm80ht27s0n	7	8	to	to	PART
gm80ht27s0n	7	9	reverse	reverse	VERB
gm80ht27s0n	7	10	the	the	DET
gm80ht27s0n	7	11	gem	gem	NOUN
gm80ht27s0n	7	12	-	-	PUNCT
gm80ht27s0n	7	13	resistant	resistant	ADJ
gm80ht27s0n	7	14	status	status	NOUN
gm80ht27s0n	7	15	of	of	ADP
gm80ht27s0n	7	16	cell	cell	NOUN
gm80ht27s0n	7	17	lines	line	NOUN
gm80ht27s0n	7	18	.	.	PUNCT
gm80ht27s0n	8	1	further	far	ADV
gm80ht27s0n	8	2	,	,	PUNCT
gm80ht27s0n	8	3	it-139	it-139	NOUN
gm80ht27s0n	8	4	,	,	PUNCT
gm80ht27s0n	8	5	a	a	DET
gm80ht27s0n	8	6	first	first	ADJ
gm80ht27s0n	8	7	in	in	ADP
gm80ht27s0n	8	8	class	class	NOUN
gm80ht27s0n	8	9	,	,	PUNCT
gm80ht27s0n	8	10	ruthenium	ruthenium	NOUN
gm80ht27s0n	8	11	based	base	VERB
gm80ht27s0n	8	12	compound	compound	NOUN
gm80ht27s0n	8	13	,	,	PUNCT
gm80ht27s0n	8	14	was	be	AUX
gm80ht27s0n	8	15	used	use	VERB
gm80ht27s0n	8	16	to	to	PART
gm80ht27s0n	8	17	target	target	VERB
gm80ht27s0n	8	18	grp78	grp78	ADJ
gm80ht27s0n	8	19	induction	induction	NOUN
gm80ht27s0n	8	20	and	and	CCONJ
gm80ht27s0n	8	21	enhanced	enhance	VERB
gm80ht27s0n	8	22	the	the	DET
gm80ht27s0n	8	23	efficacy	efficacy	NOUN
gm80ht27s0n	8	24	of	of	ADP
gm80ht27s0n	8	25	gem	gem	NOUN
gm80ht27s0n	8	26	in	in	ADP
gm80ht27s0n	8	27	vitro	vitro	X
gm80ht27s0n	8	28	and	and	CCONJ
gm80ht27s0n	8	29	in	in	ADP
gm80ht27s0n	8	30	vivo	vivo	PROPN
gm80ht27s0n	8	31	.	.	PUNCT
gm80ht27s0n	9	1	mechanistically	mechanistically	ADV
gm80ht27s0n	9	2	,	,	PUNCT
gm80ht27s0n	9	3	it	it	PRON
gm80ht27s0n	9	4	was	be	AUX
gm80ht27s0n	9	5	determined	determine	VERB
gm80ht27s0n	9	6	that	that	SCONJ
gm80ht27s0n	9	7	it-139	it-139	NOUN
gm80ht27s0n	9	8	prevents	prevent	VERB
gm80ht27s0n	9	9	the	the	DET
gm80ht27s0n	9	10	stress	stress	NOUN
gm80ht27s0n	9	11	induction	induction	NOUN
gm80ht27s0n	9	12	of	of	ADP
gm80ht27s0n	9	13	grp78	grp78	PROPN
gm80ht27s0n	9	14	,	,	PUNCT
gm80ht27s0n	9	15	as	as	ADV
gm80ht27s0n	9	16	well	well	ADV
gm80ht27s0n	9	17	as	as	ADP
gm80ht27s0n	9	18	downstream	downstream	ADJ
gm80ht27s0n	9	19	targets	target	NOUN
gm80ht27s0n	9	20	p	p	PROPN
gm80ht27s0n	9	21	-	-	PUNCT
gm80ht27s0n	9	22	akt	akt	NOUN
gm80ht27s0n	9	23	and	and	CCONJ
gm80ht27s0n	9	24	ire1a	ire1a	PROPN
gm80ht27s0n	9	25	.	.	PUNCT
gm80ht27s0n	10	1	it	it	PRON
gm80ht27s0n	10	2	was	be	AUX
gm80ht27s0n	10	3	also	also	ADV
gm80ht27s0n	10	4	determined	determine	VERB
gm80ht27s0n	10	5	that	that	SCONJ
gm80ht27s0n	10	6	grp78	grp78	ADJ
gm80ht27s0n	10	7	induction	induction	NOUN
gm80ht27s0n	10	8	may	may	AUX
gm80ht27s0n	10	9	not	not	PART
gm80ht27s0n	10	10	be	be	AUX
gm80ht27s0n	10	11	limited	limit	VERB
gm80ht27s0n	10	12	to	to	ADP
gm80ht27s0n	10	13	gem	gem	NOUN
gm80ht27s0n	10	14	,	,	PUNCT
gm80ht27s0n	10	15	and	and	CCONJ
gm80ht27s0n	10	16	that	that	SCONJ
gm80ht27s0n	10	17	dna	dna	PROPN
gm80ht27s0n	10	18	damaging	damaging	ADJ
gm80ht27s0n	10	19	agents	agent	NOUN
gm80ht27s0n	10	20	also	also	ADV
gm80ht27s0n	10	21	have	have	VERB
gm80ht27s0n	10	22	the	the	DET
gm80ht27s0n	10	23	potential	potential	NOUN
gm80ht27s0n	10	24	to	to	PART
gm80ht27s0n	10	25	induce	induce	VERB
gm80ht27s0n	10	26	the	the	DET
gm80ht27s0n	10	27	unfolded	unfolded	ADJ
gm80ht27s0n	10	28	protein	protein	NOUN
gm80ht27s0n	10	29	burden	burden	NOUN
gm80ht27s0n	10	30	in	in	ADP
gm80ht27s0n	10	31	cells	cell	NOUN
gm80ht27s0n	10	32	,	,	PUNCT
gm80ht27s0n	10	33	resulting	result	VERB
gm80ht27s0n	10	34	in	in	ADP
gm80ht27s0n	10	35	a	a	DET
gm80ht27s0n	10	36	subsequent	subsequent	ADJ
gm80ht27s0n	10	37	induction	induction	NOUN
gm80ht27s0n	10	38	of	of	ADP
gm80ht27s0n	10	39	grp78	grp78	PROPN
gm80ht27s0n	10	40	.	.	PUNCT
gm80ht27s0n	11	1	because	because	SCONJ
gm80ht27s0n	11	2	grp78	grp78	PROPN
gm80ht27s0n	11	3	has	have	AUX
gm80ht27s0n	11	4	been	be	AUX
gm80ht27s0n	11	5	connected	connect	VERB
gm80ht27s0n	11	6	to	to	ADP
gm80ht27s0n	11	7	poor	poor	ADJ
gm80ht27s0n	11	8	prognosis	prognosis	NOUN
gm80ht27s0n	11	9	across	across	ADP
gm80ht27s0n	11	10	cancer	cancer	NOUN
gm80ht27s0n	11	11	types	type	NOUN
gm80ht27s0n	11	12	and	and	CCONJ
gm80ht27s0n	11	13	treatments	treatment	NOUN
gm80ht27s0n	11	14	,	,	PUNCT
gm80ht27s0n	11	15	it	it	PRON
gm80ht27s0n	11	16	is	be	AUX
gm80ht27s0n	11	17	possible	possible	ADJ
gm80ht27s0n	11	18	that	that	SCONJ
gm80ht27s0n	11	19	grp78	grp78	PROPN
gm80ht27s0n	11	20	targeting	targeting	NOUN
gm80ht27s0n	11	21	,	,	PUNCT
gm80ht27s0n	11	22	via	via	ADP
gm80ht27s0n	11	23	it-139	it-139	NOUN
gm80ht27s0n	11	24	,	,	PUNCT
gm80ht27s0n	11	25	can	can	AUX
gm80ht27s0n	11	26	be	be	AUX
gm80ht27s0n	11	27	used	use	VERB
gm80ht27s0n	11	28	to	to	PART
gm80ht27s0n	11	29	improve	improve	VERB
gm80ht27s0n	11	30	the	the	DET
gm80ht27s0n	11	31	efficacy	efficacy	NOUN
gm80ht27s0n	11	32	of	of	ADP
gm80ht27s0n	11	33	chemotherapeutics	chemotherapeutic	NOUN
gm80ht27s0n	11	34	in	in	ADP
gm80ht27s0n	11	35	cancers	cancer	NOUN
gm80ht27s0n	11	36	beyond	beyond	ADP
gm80ht27s0n	11	37	gem	gem	NOUN
gm80ht27s0n	11	38	therapy	therapy	NOUN
gm80ht27s0n	11	39	in	in	ADP
gm80ht27s0n	11	40	pdac	pdac	NOUN
gm80ht27s0n	11	41	.	.	PUNCT