id	sid	tid	token	lemma	pos
gm80ht2727j	1	1	t	t	PROPN
gm80ht2727j	1	2	cell	cell	NOUN
gm80ht2727j	1	3	receptor	receptor	NOUN
gm80ht2727j	1	4	(	(	PUNCT
gm80ht2727j	1	5	tcr	tcr	PROPN
gm80ht2727j	1	6	)	)	PUNCT
gm80ht2727j	1	7	recognition	recognition	NOUN
gm80ht2727j	1	8	of	of	ADP
gm80ht2727j	1	9	peptides	peptide	NOUN
gm80ht2727j	1	10	bound	bind	VERB
gm80ht2727j	1	11	and	and	CCONJ
gm80ht2727j	1	12	presented	present	VERB
gm80ht2727j	1	13	by	by	ADP
gm80ht2727j	1	14	major	major	ADJ
gm80ht2727j	1	15	histocompatibility	histocompatibility	NOUN
gm80ht2727j	1	16	complex	complex	NOUN
gm80ht2727j	1	17	(	(	PUNCT
gm80ht2727j	1	18	mhc	mhc	NOUN
gm80ht2727j	1	19	)	)	PUNCT
gm80ht2727j	1	20	proteins	protein	NOUN
gm80ht2727j	1	21	initiates	initiate	VERB
gm80ht2727j	1	22	a	a	DET
gm80ht2727j	1	23	cellular	cellular	ADJ
gm80ht2727j	1	24	immune	immune	ADJ
gm80ht2727j	1	25	response	response	NOUN
gm80ht2727j	1	26	.	.	PUNCT
gm80ht2727j	2	1	the	the	DET
gm80ht2727j	2	2	stability	stability	NOUN
gm80ht2727j	2	3	of	of	ADP
gm80ht2727j	2	4	the	the	DET
gm80ht2727j	2	5	peptide	peptide	NOUN
gm80ht2727j	2	6	/	/	SYM
gm80ht2727j	2	7	mhc	mhc	PROPN
gm80ht2727j	2	8	molecule	molecule	NOUN
gm80ht2727j	2	9	is	be	AUX
gm80ht2727j	2	10	correlated	correlate	VERB
gm80ht2727j	2	11	with	with	ADP
gm80ht2727j	2	12	tcr	tcr	PROPN
gm80ht2727j	2	13	recognition	recognition	NOUN
gm80ht2727j	2	14	and	and	CCONJ
gm80ht2727j	2	15	the	the	DET
gm80ht2727j	2	16	resulting	result	VERB
gm80ht2727j	2	17	immune	immune	ADJ
gm80ht2727j	2	18	response	response	NOUN
gm80ht2727j	2	19	.	.	PUNCT
gm80ht2727j	3	1	residual	residual	ADJ
gm80ht2727j	3	2	dynamics	dynamic	NOUN
gm80ht2727j	3	3	of	of	ADP
gm80ht2727j	3	4	peptides	peptide	NOUN
gm80ht2727j	3	5	within	within	ADP
gm80ht2727j	3	6	mhc	mhc	NOUN
gm80ht2727j	3	7	binding	binding	ADJ
gm80ht2727j	3	8	grooves	groove	NOUN
gm80ht2727j	3	9	have	have	AUX
gm80ht2727j	3	10	also	also	ADV
gm80ht2727j	3	11	been	be	AUX
gm80ht2727j	3	12	suggested	suggest	VERB
gm80ht2727j	3	13	to	to	PART
gm80ht2727j	3	14	influence	influence	VERB
gm80ht2727j	3	15	tcr	tcr	PROPN
gm80ht2727j	3	16	recognition	recognition	NOUN
gm80ht2727j	3	17	,	,	PUNCT
gm80ht2727j	3	18	yet	yet	CCONJ
gm80ht2727j	3	19	nmr	nmr	PROPN
gm80ht2727j	3	20	studies	study	NOUN
gm80ht2727j	3	21	which	which	PRON
gm80ht2727j	3	22	could	could	AUX
gm80ht2727j	3	23	address	address	VERB
gm80ht2727j	3	24	this	this	PRON
gm80ht2727j	3	25	most	most	ADV
gm80ht2727j	3	26	rigorously	rigorously	ADV
gm80ht2727j	3	27	have	have	AUX
gm80ht2727j	3	28	been	be	AUX
gm80ht2727j	3	29	hindered	hinder	VERB
gm80ht2727j	3	30	by	by	ADP
gm80ht2727j	3	31	the	the	DET
gm80ht2727j	3	32	prohibitive	prohibitive	ADJ
gm80ht2727j	3	33	expense	expense	NOUN
gm80ht2727j	3	34	of	of	ADP
gm80ht2727j	3	35	isotopically	isotopically	ADV
gm80ht2727j	3	36	labeled	label	VERB
gm80ht2727j	3	37	peptide	peptide	NOUN
gm80ht2727j	3	38	and	and	CCONJ
gm80ht2727j	3	39	the	the	DET
gm80ht2727j	3	40	large	large	ADJ
gm80ht2727j	3	41	size	size	NOUN
gm80ht2727j	3	42	of	of	ADP
gm80ht2727j	3	43	the	the	DET
gm80ht2727j	3	44	peptide	peptide	NOUN
gm80ht2727j	3	45	/	/	SYM
gm80ht2727j	3	46	mhc	mhc	NOUN
gm80ht2727j	3	47	complex	complex	NOUN
gm80ht2727j	3	48	.	.	PUNCT
gm80ht2727j	4	1	this	this	DET
gm80ht2727j	4	2	study	study	NOUN
gm80ht2727j	4	3	describe	describe	VERB
gm80ht2727j	4	4	methodologies	methodology	NOUN
gm80ht2727j	4	5	for	for	ADP
gm80ht2727j	4	6	characterizing	characterize	VERB
gm80ht2727j	4	7	peptide	peptide	NOUN
gm80ht2727j	4	8	dynamics	dynamic	NOUN
gm80ht2727j	4	9	within	within	ADP
gm80ht2727j	4	10	mhc	mhc	NOUN
gm80ht2727j	4	11	binding	bind	VERB
gm80ht2727j	4	12	grooves	groove	NOUN
gm80ht2727j	4	13	via	via	ADP
gm80ht2727j	4	14	nmr	nmr	NOUN
gm80ht2727j	4	15	,	,	PUNCT
gm80ht2727j	4	16	using	use	VERB
gm80ht2727j	4	17	a	a	DET
gm80ht2727j	4	18	biosynthetic	biosynthetic	ADJ
gm80ht2727j	4	19	approach	approach	NOUN
gm80ht2727j	4	20	for	for	ADP
gm80ht2727j	4	21	producing	produce	VERB
gm80ht2727j	4	22	labeled	label	VERB
gm80ht2727j	4	23	peptide	peptide	NOUN
gm80ht2727j	4	24	in	in	ADP
gm80ht2727j	4	25	which	which	PRON
gm80ht2727j	4	26	the	the	DET
gm80ht2727j	4	27	peptide	peptide	NOUN
gm80ht2727j	4	28	is	be	AUX
gm80ht2727j	4	29	fused	fuse	VERB
gm80ht2727j	4	30	to	to	ADP
gm80ht2727j	4	31	ubiquitin	ubiquitin	NOUN
gm80ht2727j	4	32	and	and	CCONJ
gm80ht2727j	4	33	a	a	DET
gm80ht2727j	4	34	ubiquitin	ubiquitin	NOUN
gm80ht2727j	4	35	dehydrolase	dehydrolase	NOUN
gm80ht2727j	4	36	used	use	VERB
gm80ht2727j	4	37	to	to	PART
gm80ht2727j	4	38	liberate	liberate	VERB
gm80ht2727j	4	39	the	the	DET
gm80ht2727j	4	40	peptide	peptide	NOUN
gm80ht2727j	4	41	.	.	PUNCT
gm80ht2727j	5	1	using	use	VERB
gm80ht2727j	5	2	the	the	DET
gm80ht2727j	5	3	tax11	tax11	PROPN
gm80ht2727j	5	4	-	-	PUNCT
gm80ht2727j	5	5	19	19	NUM
gm80ht2727j	5	6	peptide	peptide	NOUN
gm80ht2727j	5	7	bound	bind	VERB
gm80ht2727j	5	8	to	to	ADP
gm80ht2727j	5	9	the	the	DET
gm80ht2727j	5	10	45	45	NUM
gm80ht2727j	5	11	kd	kd	PROPN
gm80ht2727j	5	12	human	human	ADJ
gm80ht2727j	5	13	class	class	NOUN
gm80ht2727j	6	1	i	i	PRON
gm80ht2727j	6	2	mhc	mhc	INTJ
gm80ht2727j	6	3	hla	hla	NOUN
gm80ht2727j	6	4	-	-	NOUN
gm80ht2727j	6	5	a2	a2	X
gm80ht2727j	6	6	as	as	ADP
gm80ht2727j	6	7	a	a	DET
gm80ht2727j	6	8	model	model	NOUN
gm80ht2727j	6	9	system	system	NOUN
gm80ht2727j	6	10	,	,	PUNCT
gm80ht2727j	6	11	it	it	PRON
gm80ht2727j	6	12	is	be	AUX
gm80ht2727j	6	13	evident	evident	ADJ
gm80ht2727j	6	14	that	that	SCONJ
gm80ht2727j	6	15	peptides	peptide	NOUN
gm80ht2727j	6	16	generated	generate	VERB
gm80ht2727j	6	17	in	in	ADP
gm80ht2727j	6	18	this	this	DET
gm80ht2727j	6	19	manner	manner	NOUN
gm80ht2727j	6	20	can	can	AUX
gm80ht2727j	6	21	be	be	AUX
gm80ht2727j	6	22	well	well	ADV
gm80ht2727j	6	23	characterized	characterize	VERB
gm80ht2727j	6	24	in	in	ADP
gm80ht2727j	6	25	mhc	mhc	NOUN
gm80ht2727j	6	26	binding	bind	VERB
gm80ht2727j	6	27	grooves	groove	NOUN
gm80ht2727j	6	28	by	by	ADP
gm80ht2727j	6	29	nmr	nmr	NOUN
gm80ht2727j	6	30	,	,	PUNCT
gm80ht2727j	6	31	providing	provide	VERB
gm80ht2727j	6	32	the	the	DET
gm80ht2727j	6	33	opportunity	opportunity	NOUN
gm80ht2727j	6	34	to	to	PART
gm80ht2727j	6	35	more	more	ADV
gm80ht2727j	6	36	precisely	precisely	ADV
gm80ht2727j	6	37	study	study	VERB
gm80ht2727j	6	38	the	the	DET
gm80ht2727j	6	39	role	role	NOUN
gm80ht2727j	6	40	of	of	ADP
gm80ht2727j	6	41	peptide	peptide	NOUN
gm80ht2727j	6	42	dynamics	dynamic	NOUN
gm80ht2727j	6	43	in	in	ADP
gm80ht2727j	6	44	tcr	tcr	PROPN
gm80ht2727j	6	45	recognition	recognition	NOUN
gm80ht2727j	6	46	,	,	PUNCT
gm80ht2727j	6	47	specificity	specificity	NOUN
gm80ht2727j	6	48	,	,	PUNCT
gm80ht2727j	6	49	and	and	CCONJ
gm80ht2727j	6	50	cross-reactivity.using	cross-reactivity.use	VERB
gm80ht2727j	6	51	both	both	PRON
gm80ht2727j	6	52	nmr	nmr	NOUN
gm80ht2727j	6	53	and	and	CCONJ
gm80ht2727j	6	54	molecular	molecular	ADJ
gm80ht2727j	6	55	dynamics	dynamic	NOUN
gm80ht2727j	6	56	simulations	simulation	NOUN
gm80ht2727j	6	57	,	,	PUNCT
gm80ht2727j	6	58	the	the	DET
gm80ht2727j	6	59	principles	principle	NOUN
gm80ht2727j	6	60	governing	govern	VERB
gm80ht2727j	6	61	conformational	conformational	ADJ
gm80ht2727j	6	62	changes	change	NOUN
gm80ht2727j	6	63	observed	observe	VERB
gm80ht2727j	6	64	in	in	ADP
gm80ht2727j	6	65	tax	tax	NOUN
gm80ht2727j	6	66	(	(	PUNCT
gm80ht2727j	6	67	llfgypvyv	llfgypvyv	PROPN
gm80ht2727j	6	68	)	)	PUNCT
gm80ht2727j	6	69	and	and	CCONJ
gm80ht2727j	6	70	p6a	p6a	VERB
gm80ht2727j	6	71	-	-	PUNCT
gm80ht2727j	6	72	tax	tax	NOUN
gm80ht2727j	6	73	(	(	PUNCT
gm80ht2727j	6	74	llfgyavyv	llfgyavyv	PROPN
gm80ht2727j	6	75	)	)	PUNCT
gm80ht2727j	6	76	peptide	peptide	NOUN
gm80ht2727j	6	77	/	/	SYM
gm80ht2727j	6	78	mhc	mhc	ADV
gm80ht2727j	6	79	upon	upon	SCONJ
gm80ht2727j	6	80	tcr	tcr	NOUN
gm80ht2727j	6	81	binding	bind	VERB
gm80ht2727j	6	82	were	be	AUX
gm80ht2727j	6	83	examined	examine	VERB
gm80ht2727j	6	84	.	.	PUNCT
gm80ht2727j	7	1	nmr	nmr	PROPN
gm80ht2727j	7	2	results	result	NOUN
gm80ht2727j	7	3	indicated	indicate	VERB
gm80ht2727j	7	4	that	that	SCONJ
gm80ht2727j	7	5	despite	despite	SCONJ
gm80ht2727j	7	6	nearly	nearly	ADV
gm80ht2727j	7	7	identical	identical	ADJ
gm80ht2727j	7	8	crystallographic	crystallographic	ADJ
gm80ht2727j	7	9	structures	structure	NOUN
gm80ht2727j	7	10	,	,	PUNCT
gm80ht2727j	7	11	there	there	PRON
gm80ht2727j	7	12	are	be	VERB
gm80ht2727j	7	13	differences	difference	NOUN
gm80ht2727j	7	14	in	in	ADP
gm80ht2727j	7	15	the	the	DET
gm80ht2727j	7	16	conformations	conformation	NOUN
gm80ht2727j	7	17	of	of	ADP
gm80ht2727j	7	18	the	the	DET
gm80ht2727j	7	19	two	two	NUM
gm80ht2727j	7	20	peptide	peptide	NOUN
gm80ht2727j	7	21	/	/	SYM
gm80ht2727j	7	22	hla	hla	NOUN
gm80ht2727j	7	23	-	-	PUNCT
gm80ht2727j	7	24	a2	a2	ADJ
gm80ht2727j	7	25	complexes	complex	NOUN
gm80ht2727j	7	26	as	as	ADP
gm80ht2727j	7	27	a	a	DET
gm80ht2727j	7	28	function	function	NOUN
gm80ht2727j	7	29	of	of	ADP
gm80ht2727j	7	30	increasing	increase	VERB
gm80ht2727j	7	31	temperature	temperature	NOUN
gm80ht2727j	7	32	.	.	PUNCT
gm80ht2727j	8	1	analysis	analysis	NOUN
gm80ht2727j	8	2	of	of	ADP
gm80ht2727j	8	3	unrestrained	unrestrained	ADJ
gm80ht2727j	8	4	molecular	molecular	ADJ
gm80ht2727j	8	5	dynamics	dynamic	NOUN
gm80ht2727j	8	6	simulation	simulation	NOUN
gm80ht2727j	8	7	at	at	ADP
gm80ht2727j	8	8	300	300	NUM
gm80ht2727j	8	9	and	and	CCONJ
gm80ht2727j	8	10	330	330	NUM
gm80ht2727j	8	11	k	k	PROPN
gm80ht2727j	8	12	provided	provide	VERB
gm80ht2727j	8	13	insight	insight	NOUN
gm80ht2727j	8	14	into	into	ADP
gm80ht2727j	8	15	these	these	DET
gm80ht2727j	8	16	differences	difference	NOUN
gm80ht2727j	8	17	,	,	PUNCT
gm80ht2727j	8	18	showing	show	VERB
gm80ht2727j	8	19	that	that	SCONJ
gm80ht2727j	8	20	the	the	DET
gm80ht2727j	8	21	central	central	ADJ
gm80ht2727j	8	22	region	region	NOUN
gm80ht2727j	8	23	of	of	ADP
gm80ht2727j	8	24	both	both	DET
gm80ht2727j	8	25	peptides	peptide	NOUN
gm80ht2727j	8	26	sampled	sample	VERB
gm80ht2727j	8	27	alternative	alternative	ADJ
gm80ht2727j	8	28	conformations	conformation	NOUN
gm80ht2727j	8	29	.	.	PUNCT
gm80ht2727j	9	1	in	in	ADP
gm80ht2727j	9	2	addition	addition	NOUN
gm80ht2727j	9	3	,	,	PUNCT
gm80ht2727j	9	4	the	the	DET
gm80ht2727j	9	5	studies	study	NOUN
gm80ht2727j	9	6	suggested	suggest	VERB
gm80ht2727j	9	7	that	that	SCONJ
gm80ht2727j	9	8	conformational	conformational	ADJ
gm80ht2727j	9	9	changes	change	NOUN
gm80ht2727j	9	10	observed	observe	VERB
gm80ht2727j	9	11	upon	upon	SCONJ
gm80ht2727j	9	12	tcr	tcr	NOUN
gm80ht2727j	9	13	binding	bind	VERB
gm80ht2727j	9	14	to	to	ADP
gm80ht2727j	9	15	mhc	mhc	NOUN
gm80ht2727j	9	16	can	can	AUX
gm80ht2727j	9	17	not	not	PART
gm80ht2727j	9	18	be	be	AUX
gm80ht2727j	9	19	explained	explain	VERB
gm80ht2727j	9	20	solely	solely	ADV
gm80ht2727j	9	21	as	as	ADP
gm80ht2727j	9	22	an	an	DET
gm80ht2727j	9	23	induced	induce	VERB
gm80ht2727j	9	24	-	-	PUNCT
gm80ht2727j	9	25	fit	fit	NOUN
gm80ht2727j	9	26	or	or	CCONJ
gm80ht2727j	9	27	selection	selection	NOUN
gm80ht2727j	9	28	of	of	ADP
gm80ht2727j	9	29	a	a	DET
gm80ht2727j	9	30	pre	pre	ADJ
gm80ht2727j	9	31	-	-	ADJ
gm80ht2727j	9	32	existing	existing	ADJ
gm80ht2727j	9	33	equilibrium	equilibrium	NOUN
gm80ht2727j	9	34	conformation	conformation	NOUN
gm80ht2727j	9	35	but	but	CCONJ
gm80ht2727j	9	36	rather	rather	ADV
gm80ht2727j	9	37	a	a	DET
gm80ht2727j	9	38	combination	combination	NOUN
gm80ht2727j	9	39	of	of	ADP
gm80ht2727j	9	40	these	these	DET
gm80ht2727j	9	41	two	two	NUM
gm80ht2727j	9	42	binding	bind	VERB
gm80ht2727j	9	43	mechanisms.in	mechanisms.in	X
gm80ht2727j	9	44	the	the	DET
gm80ht2727j	9	45	case	case	NOUN
gm80ht2727j	9	46	of	of	ADP
gm80ht2727j	9	47	the	the	DET
gm80ht2727j	9	48	mart-1	mart-1	NUM
gm80ht2727j	9	49	melanoma	melanoma	NOUN
gm80ht2727j	9	50	antigen	antigen	NOUN
gm80ht2727j	9	51	(	(	PUNCT
gm80ht2727j	9	52	aagigiltv	aagigiltv	PROPN
gm80ht2727j	9	53	)	)	PUNCT
gm80ht2727j	9	54	,	,	PUNCT
gm80ht2727j	9	55	despite	despite	SCONJ
gm80ht2727j	9	56	improving	improve	VERB
gm80ht2727j	9	57	peptide	peptide	NOUN
gm80ht2727j	9	58	binding	bind	VERB
gm80ht2727j	9	59	40	40	NUM
gm80ht2727j	9	60	-	-	ADJ
gm80ht2727j	9	61	fold	fold	ADJ
gm80ht2727j	9	62	,	,	PUNCT
gm80ht2727j	9	63	replacement	replacement	NOUN
gm80ht2727j	9	64	of	of	ADP
gm80ht2727j	9	65	the	the	DET
gm80ht2727j	9	66	suboptimal	suboptimal	ADJ
gm80ht2727j	9	67	alanine	alanine	NOUN
gm80ht2727j	9	68	at	at	ADP
gm80ht2727j	9	69	position	position	NOUN
gm80ht2727j	9	70	2	2	NUM
gm80ht2727j	9	71	with	with	ADP
gm80ht2727j	9	72	leucine	leucine	NOUN
gm80ht2727j	9	73	(	(	PUNCT
gm80ht2727j	9	74	algigiltv	algigiltv	PROPN
gm80ht2727j	9	75	)	)	PUNCT
gm80ht2727j	9	76	completely	completely	ADV
gm80ht2727j	9	77	abolished	abolish	VERB
gm80ht2727j	9	78	t	t	PROPN
gm80ht2727j	9	79	cell	cell	NOUN
gm80ht2727j	9	80	recognition	recognition	NOUN
gm80ht2727j	9	81	.	.	PUNCT
gm80ht2727j	10	1	although	although	SCONJ
gm80ht2727j	10	2	crystallographic	crystallographic	ADJ
gm80ht2727j	10	3	structures	structure	NOUN
gm80ht2727j	10	4	indicated	indicate	VERB
gm80ht2727j	10	5	similar	similar	ADJ
gm80ht2727j	10	6	backbone	backbone	NOUN
gm80ht2727j	10	7	conformations	conformation	NOUN
gm80ht2727j	10	8	of	of	ADP
gm80ht2727j	10	9	both	both	DET
gm80ht2727j	10	10	peptides	peptide	NOUN
gm80ht2727j	10	11	,	,	PUNCT
gm80ht2727j	10	12	molecular	molecular	ADJ
gm80ht2727j	10	13	dynamics	dynamic	NOUN
gm80ht2727j	10	14	simulations	simulation	NOUN
gm80ht2727j	10	15	and	and	CCONJ
gm80ht2727j	10	16	nmr	nmr	NOUN
gm80ht2727j	10	17	at	at	ADP
gm80ht2727j	10	18	multiple	multiple	ADJ
gm80ht2727j	10	19	temperatures	temperature	NOUN
gm80ht2727j	10	20	showed	show	VERB
gm80ht2727j	10	21	alternative	alternative	ADJ
gm80ht2727j	10	22	conformations	conformation	NOUN
gm80ht2727j	10	23	in	in	ADP
gm80ht2727j	10	24	the	the	DET
gm80ht2727j	10	25	modified	modify	VERB
gm80ht2727j	10	26	peptide	peptide	NOUN
gm80ht2727j	10	27	.	.	PUNCT
gm80ht2727j	11	1	this	this	PRON
gm80ht2727j	11	2	tracked	track	VERB
gm80ht2727j	11	3	closely	closely	ADV
gm80ht2727j	11	4	with	with	ADP
gm80ht2727j	11	5	the	the	DET
gm80ht2727j	11	6	crystallographic	crystallographic	ADJ
gm80ht2727j	11	7	results	result	NOUN
gm80ht2727j	11	8	,	,	PUNCT
gm80ht2727j	11	9	showing	show	VERB
gm80ht2727j	11	10	that	that	SCONJ
gm80ht2727j	11	11	the	the	DET
gm80ht2727j	11	12	modified	modify	VERB
gm80ht2727j	11	13	peptide	peptide	NOUN
gm80ht2727j	11	14	samples	sample	NOUN
gm80ht2727j	11	15	all	all	DET
gm80ht2727j	11	16	the	the	DET
gm80ht2727j	11	17	conformations	conformation	NOUN
gm80ht2727j	11	18	observed	observe	VERB
gm80ht2727j	11	19	crystallographically	crystallographically	ADV
gm80ht2727j	11	20	.	.	PUNCT
gm80ht2727j	12	1	collectively	collectively	ADV
gm80ht2727j	12	2	,	,	PUNCT
gm80ht2727j	12	3	these	these	DET
gm80ht2727j	12	4	observations	observation	NOUN
gm80ht2727j	12	5	reveal	reveal	VERB
gm80ht2727j	12	6	that	that	SCONJ
gm80ht2727j	12	7	contrary	contrary	ADJ
gm80ht2727j	12	8	to	to	ADP
gm80ht2727j	12	9	the	the	DET
gm80ht2727j	12	10	usual	usual	ADJ
gm80ht2727j	12	11	considerations	consideration	NOUN
gm80ht2727j	12	12	regarding	regard	VERB
gm80ht2727j	12	13	peptide	peptide	NOUN
gm80ht2727j	12	14	antigenicity	antigenicity	NOUN
gm80ht2727j	12	15	,	,	PUNCT
gm80ht2727j	12	16	antigen	antigen	NOUN
gm80ht2727j	12	17	dynamical	dynamical	ADJ
gm80ht2727j	12	18	properties	property	NOUN
gm80ht2727j	12	19	can	can	AUX
gm80ht2727j	12	20	profoundly	profoundly	ADV
gm80ht2727j	12	21	influence	influence	VERB
gm80ht2727j	12	22	t	t	PROPN
gm80ht2727j	12	23	cell	cell	NOUN
gm80ht2727j	12	24	recognition	recognition	NOUN
gm80ht2727j	12	25	.	.	PUNCT
gm80ht2727j	13	1	further	far	ADV
gm80ht2727j	13	2	,	,	PUNCT
gm80ht2727j	13	3	these	these	DET
gm80ht2727j	13	4	observations	observation	NOUN
gm80ht2727j	13	5	demonstrate	demonstrate	VERB
gm80ht2727j	13	6	that	that	SCONJ
gm80ht2727j	13	7	seemingly	seemingly	ADV
gm80ht2727j	13	8	minor	minor	ADJ
gm80ht2727j	13	9	modifications	modification	NOUN
gm80ht2727j	13	10	within	within	ADP
gm80ht2727j	13	11	a	a	DET
gm80ht2727j	13	12	peptide	peptide	NOUN
gm80ht2727j	13	13	can	can	AUX
gm80ht2727j	13	14	have	have	VERB
gm80ht2727j	13	15	dramatic	dramatic	ADJ
gm80ht2727j	13	16	unanticipated	unanticipated	ADJ
gm80ht2727j	13	17	consequences	consequence	NOUN
gm80ht2727j	13	18	such	such	ADJ
gm80ht2727j	13	19	as	as	ADP
gm80ht2727j	13	20	increasing	increase	VERB
gm80ht2727j	13	21	antigenic	antigenic	ADJ
gm80ht2727j	13	22	peptide	peptide	NOUN
gm80ht2727j	13	23	dynamics	dynamic	NOUN
gm80ht2727j	13	24	,	,	PUNCT
gm80ht2727j	13	25	with	with	ADP
gm80ht2727j	13	26	implications	implication	NOUN
gm80ht2727j	13	27	for	for	ADP
gm80ht2727j	13	28	tcr	tcr	NOUN
gm80ht2727j	13	29	binding	binding	NOUN
gm80ht2727j	13	30	and	and	CCONJ
gm80ht2727j	13	31	kinetics	kinetic	NOUN
gm80ht2727j	13	32	.	.	PUNCT