id sid tid token lemma pos g732d794p3k 1 1 global global ADJ g732d794p3k 1 2 changes change NOUN g732d794p3k 1 3 have have AUX g732d794p3k 1 4 caused cause VERB g732d794p3k 1 5 vector vector NOUN g732d794p3k 1 6 - - PUNCT g732d794p3k 1 7 borne bear VERB g732d794p3k 1 8 diseases disease NOUN g732d794p3k 1 9 ( ( PUNCT g732d794p3k 1 10 vbds vbds NOUN g732d794p3k 1 11 ) ) PUNCT g732d794p3k 1 12 to to PART g732d794p3k 1 13 resurge resurge VERB g732d794p3k 1 14 , , PUNCT g732d794p3k 1 15 inflicting inflict VERB g732d794p3k 1 16 high high ADJ g732d794p3k 1 17 morbidity morbidity NOUN g732d794p3k 1 18 and and CCONJ g732d794p3k 1 19 mortality mortality NOUN g732d794p3k 1 20 at at ADP g732d794p3k 1 21 a a DET g732d794p3k 1 22 disproportionate disproportionate ADJ g732d794p3k 1 23 level level NOUN g732d794p3k 1 24 in in ADP g732d794p3k 1 25 the the DET g732d794p3k 1 26 developing develop VERB g732d794p3k 1 27 world world NOUN g732d794p3k 1 28 . . PUNCT g732d794p3k 2 1 while while SCONJ g732d794p3k 2 2 vaccine vaccine NOUN g732d794p3k 2 3 candidates candidate NOUN g732d794p3k 2 4 are be AUX g732d794p3k 2 5 moving move VERB g732d794p3k 2 6 through through ADP g732d794p3k 2 7 the the DET g732d794p3k 2 8 developmental developmental ADJ g732d794p3k 2 9 pipeline pipeline NOUN g732d794p3k 2 10 , , PUNCT g732d794p3k 2 11 insecticides insecticide NOUN g732d794p3k 2 12 are be AUX g732d794p3k 2 13 playing play VERB g732d794p3k 2 14 a a DET g732d794p3k 2 15 fundamental fundamental ADJ g732d794p3k 2 16 role role NOUN g732d794p3k 2 17 in in ADP g732d794p3k 2 18 curbing curb VERB g732d794p3k 2 19 vector vector NOUN g732d794p3k 2 20 - - PUNCT g732d794p3k 2 21 transmitted transmit VERB g732d794p3k 2 22 diseases disease NOUN g732d794p3k 2 23 . . PUNCT g732d794p3k 3 1 the the DET g732d794p3k 3 2 worldwide worldwide ADJ g732d794p3k 3 3 emergence emergence NOUN g732d794p3k 3 4 of of ADP g732d794p3k 3 5 insecticide insecticide PROPN g732d794p3k 3 6 resistance resistance PROPN g732d794p3k 3 7 underscores underscore VERB g732d794p3k 3 8 the the DET g732d794p3k 3 9 necessity necessity NOUN g732d794p3k 3 10 of of ADP g732d794p3k 3 11 discovering discover VERB g732d794p3k 3 12 new new ADJ g732d794p3k 3 13 insecticides insecticide NOUN g732d794p3k 3 14 with with ADP g732d794p3k 3 15 novel novel ADJ g732d794p3k 3 16 modes mode NOUN g732d794p3k 3 17 of of ADP g732d794p3k 3 18 action action NOUN g732d794p3k 3 19 . . PUNCT g732d794p3k 4 1 recently recently ADV g732d794p3k 4 2 , , PUNCT g732d794p3k 4 3 g g NOUN g732d794p3k 4 4 - - PUNCT g732d794p3k 4 5 protein protein NOUN g732d794p3k 4 6 coupled couple VERB g732d794p3k 4 7 receptors receptor NOUN g732d794p3k 4 8 ( ( PUNCT g732d794p3k 4 9 gpcr gpcr ADJ g732d794p3k 4 10 ) ) PUNCT g732d794p3k 4 11 have have AUX g732d794p3k 4 12 been be AUX g732d794p3k 4 13 identified identify VERB g732d794p3k 4 14 as as ADP g732d794p3k 4 15 a a DET g732d794p3k 4 16 lucrative lucrative ADJ g732d794p3k 4 17 drug drug NOUN g732d794p3k 4 18 target target NOUN g732d794p3k 4 19 due due ADP g732d794p3k 4 20 to to ADP g732d794p3k 4 21 their their PRON g732d794p3k 4 22 involvement involvement NOUN g732d794p3k 4 23 in in ADP g732d794p3k 4 24 a a DET g732d794p3k 4 25 diverse diverse ADJ g732d794p3k 4 26 array array NOUN g732d794p3k 4 27 of of ADP g732d794p3k 4 28 insect insect NOUN g732d794p3k 4 29 physiological physiological ADJ g732d794p3k 4 30 and and CCONJ g732d794p3k 4 31 behavioral behavioral ADJ g732d794p3k 4 32 processes process NOUN g732d794p3k 4 33 . . PUNCT g732d794p3k 5 1 in in ADP g732d794p3k 5 2 particular particular ADJ g732d794p3k 5 3 , , PUNCT g732d794p3k 5 4 the the DET g732d794p3k 5 5 serotonin serotonin NOUN g732d794p3k 5 6 ( ( PUNCT g732d794p3k 5 7 5 5 NUM g732d794p3k 5 8 - - PUNCT g732d794p3k 5 9 ht ht ADJ g732d794p3k 5 10 ) ) PUNCT g732d794p3k 5 11 gpcr gpcr ADJ g732d794p3k 5 12 family family NOUN g732d794p3k 5 13 , , PUNCT g732d794p3k 5 14 subdivided subdivide VERB g732d794p3k 5 15 into into ADP g732d794p3k 5 16 5 5 NUM g732d794p3k 5 17 - - PUNCT g732d794p3k 5 18 ht1 ht1 NOUN g732d794p3k 5 19 , , PUNCT g732d794p3k 5 20 5 5 NUM g732d794p3k 5 21 - - SYM g732d794p3k 5 22 ht2 ht2 NOUN g732d794p3k 5 23 and and CCONJ g732d794p3k 5 24 5 5 NUM g732d794p3k 5 25 - - PUNCT g732d794p3k 5 26 ht7 ht7 PROPN g732d794p3k 5 27 , , PUNCT g732d794p3k 5 28 has have AUX g732d794p3k 5 29 been be AUX g732d794p3k 5 30 implicated implicate VERB g732d794p3k 5 31 in in ADP g732d794p3k 5 32 processes process NOUN g732d794p3k 5 33 paramount paramount ADV g732d794p3k 5 34 to to ADP g732d794p3k 5 35 vectorial vectorial ADJ g732d794p3k 5 36 capacity capacity NOUN g732d794p3k 5 37 including include VERB g732d794p3k 5 38 feeding feeding NOUN g732d794p3k 5 39 and and CCONJ g732d794p3k 5 40 locomotion locomotion NOUN g732d794p3k 5 41 . . PUNCT g732d794p3k 6 1 availability availability NOUN g732d794p3k 6 2 of of ADP g732d794p3k 6 3 deep deep ADJ g732d794p3k 6 4 - - PUNCT g732d794p3k 6 5 sequencing sequence VERB g732d794p3k 6 6 projects project NOUN g732d794p3k 6 7 and and CCONJ g732d794p3k 6 8 highly highly ADV g732d794p3k 6 9 conserved conserved ADJ g732d794p3k 6 10 regions region NOUN g732d794p3k 6 11 of of ADP g732d794p3k 6 12 amino amino NOUN g732d794p3k 6 13 acids acid NOUN g732d794p3k 6 14 within within ADP g732d794p3k 6 15 the the DET g732d794p3k 6 16 family family NOUN g732d794p3k 6 17 promoted promote VERB g732d794p3k 6 18 the the DET g732d794p3k 6 19 identification identification NOUN g732d794p3k 6 20 of of ADP g732d794p3k 6 21 5 5 NUM g732d794p3k 6 22 - - PUNCT g732d794p3k 6 23 ht ht NOUN g732d794p3k 6 24 gpcr gpcr ADJ g732d794p3k 6 25 target target NOUN g732d794p3k 6 26 genes gene NOUN g732d794p3k 6 27 in in ADP g732d794p3k 6 28 aedes aedes PROPN g732d794p3k 6 29 aegypti aegypti PROPN g732d794p3k 6 30 and and CCONJ g732d794p3k 6 31 anopheles anophele NOUN g732d794p3k 6 32 gambiae gambiae NOUN g732d794p3k 6 33 through through ADP g732d794p3k 6 34 sequence sequence NOUN g732d794p3k 6 35 similarity similarity NOUN g732d794p3k 6 36 and and CCONJ g732d794p3k 6 37 homology homology NOUN g732d794p3k 6 38 - - PUNCT g732d794p3k 6 39 based base VERB g732d794p3k 6 40 searches search NOUN g732d794p3k 6 41 . . PUNCT g732d794p3k 7 1 stage stage NOUN g732d794p3k 7 2 - - PUNCT g732d794p3k 7 3 specific specific ADJ g732d794p3k 7 4 expression expression NOUN g732d794p3k 7 5 profile profile NOUN g732d794p3k 7 6 determined determine VERB g732d794p3k 7 7 by by ADP g732d794p3k 7 8 quantitative quantitative ADJ g732d794p3k 7 9 rt rt NOUN g732d794p3k 7 10 - - PUNCT g732d794p3k 7 11 pcr pcr NOUN g732d794p3k 7 12 aided aid VERB g732d794p3k 7 13 in in ADP g732d794p3k 7 14 the the DET g732d794p3k 7 15 prioritization prioritization NOUN g732d794p3k 7 16 of of ADP g732d794p3k 7 17 genes gene NOUN g732d794p3k 7 18 for for ADP g732d794p3k 7 19 targeting target VERB g732d794p3k 7 20 of of ADP g732d794p3k 7 21 adult adult NOUN g732d794p3k 7 22 mosquitoes mosquito NOUN g732d794p3k 7 23 versus versus ADP g732d794p3k 7 24 immature immature ADJ g732d794p3k 7 25 stages stage NOUN g732d794p3k 7 26 , , PUNCT g732d794p3k 7 27 but but CCONJ g732d794p3k 7 28 most most ADV g732d794p3k 7 29 importantly importantly ADV g732d794p3k 7 30 , , PUNCT g732d794p3k 7 31 significant significant ADJ g732d794p3k 7 32 levels level NOUN g732d794p3k 7 33 of of ADP g732d794p3k 7 34 expression expression NOUN g732d794p3k 7 35 were be AUX g732d794p3k 7 36 observed observe VERB g732d794p3k 7 37 in in ADP g732d794p3k 7 38 the the DET g732d794p3k 7 39 adult adult NOUN g732d794p3k 7 40 female female ADJ g732d794p3k 7 41 head head NOUN g732d794p3k 7 42 . . PUNCT g732d794p3k 8 1 target target NOUN g732d794p3k 8 2 receptors receptor NOUN g732d794p3k 8 3 from from ADP g732d794p3k 8 4 each each DET g732d794p3k 8 5 5 5 NUM g732d794p3k 8 6 - - PUNCT g732d794p3k 8 7 ht ht NOUN g732d794p3k 8 8 subfamily subfamily NOUN g732d794p3k 8 9 were be AUX g732d794p3k 8 10 cloned clone VERB g732d794p3k 8 11 into into ADP g732d794p3k 8 12 the the DET g732d794p3k 8 13 pf9a pf9a PROPN g732d794p3k 8 14 cmv cmv PROPN g732d794p3k 8 15 hrluc hrluc PROPN g732d794p3k 8 16 - - PUNCT g732d794p3k 8 17 neo neo PROPN g732d794p3k 8 18 flexi flexi ADJ g732d794p3k 8 19 vector vector NOUN g732d794p3k 8 20 and and CCONJ g732d794p3k 8 21 expressed express VERB g732d794p3k 8 22 transiently transiently ADV g732d794p3k 8 23 in in ADP g732d794p3k 8 24 the the DET g732d794p3k 8 25 human human ADJ g732d794p3k 8 26 embryonic embryonic NOUN g732d794p3k 8 27 kidney kidney NOUN g732d794p3k 8 28 ( ( PUNCT g732d794p3k 8 29 hek-293 hek-293 SPACE g732d794p3k 8 30 ) ) PUNCT g732d794p3k 8 31 cell cell NOUN g732d794p3k 8 32 line line NOUN g732d794p3k 8 33 . . PUNCT g732d794p3k 9 1 the the DET g732d794p3k 9 2 gloresponse gloresponse PROPN g732d794p3k 9 3 reporter reporter NOUN g732d794p3k 9 4 system system NOUN g732d794p3k 9 5 and and CCONJ g732d794p3k 9 6 fluo-4 fluo-4 NUM g732d794p3k 9 7 direct direct ADJ g732d794p3k 9 8 calcium calcium NOUN g732d794p3k 9 9 assay assay PROPN g732d794p3k 9 10 were be AUX g732d794p3k 9 11 utilized utilize VERB g732d794p3k 9 12 to to PART g732d794p3k 9 13 characterize characterize VERB g732d794p3k 9 14 the the DET g732d794p3k 9 15 receptors receptor NOUN g732d794p3k 9 16 . . PUNCT g732d794p3k 10 1 potential potential ADJ g732d794p3k 10 2 agonist agonist NOUN g732d794p3k 10 3 and and CCONJ g732d794p3k 10 4 antagonist antagonist NOUN g732d794p3k 10 5 activity activity NOUN g732d794p3k 10 6 was be AUX g732d794p3k 10 7 analyzed analyze VERB g732d794p3k 10 8 through through ADP g732d794p3k 10 9 cell cell NOUN g732d794p3k 10 10 - - PUNCT g732d794p3k 10 11 based base VERB g732d794p3k 10 12 assays assay NOUN g732d794p3k 10 13 and and CCONJ g732d794p3k 10 14 dose dose NOUN g732d794p3k 10 15 - - PUNCT g732d794p3k 10 16 response response NOUN g732d794p3k 10 17 curves curve NOUN g732d794p3k 10 18 . . PUNCT g732d794p3k 11 1 chemical chemical ADJ g732d794p3k 11 2 compounds compound NOUN g732d794p3k 11 3 reported report VERB g732d794p3k 11 4 to to PART g732d794p3k 11 5 effect effect VERB g732d794p3k 11 6 invertebrate invertebrate NOUN g732d794p3k 11 7 5 5 NUM g732d794p3k 11 8 - - PUNCT g732d794p3k 11 9 ht ht NOUN g732d794p3k 11 10 receptors receptor NOUN g732d794p3k 11 11 were be AUX g732d794p3k 11 12 tested test VERB g732d794p3k 11 13 for for ADP g732d794p3k 11 14 their their PRON g732d794p3k 11 15 impact impact NOUN g732d794p3k 11 16 on on ADP g732d794p3k 11 17 locomotion locomotion NOUN g732d794p3k 11 18 , , PUNCT g732d794p3k 11 19 sugar sugar NOUN g732d794p3k 11 20 feeding feeding NOUN g732d794p3k 11 21 , , PUNCT g732d794p3k 11 22 and and CCONJ g732d794p3k 11 23 blood blood NOUN g732d794p3k 11 24 feeding feed VERB g732d794p3k 11 25 via via ADP g732d794p3k 11 26 in in ADP g732d794p3k 11 27 vivo vivo PROPN g732d794p3k 11 28 behavioral behavioral ADJ g732d794p3k 11 29 assays assay NOUN g732d794p3k 11 30 . . PUNCT g732d794p3k 12 1 results result NOUN g732d794p3k 12 2 suggest suggest VERB g732d794p3k 12 3 that that SCONJ g732d794p3k 12 4 the the DET g732d794p3k 12 5 serotonergic serotonergic ADJ g732d794p3k 12 6 system system NOUN g732d794p3k 12 7 is be AUX g732d794p3k 12 8 involved involve VERB g732d794p3k 12 9 in in ADP g732d794p3k 12 10 the the DET g732d794p3k 12 11 modulation modulation NOUN g732d794p3k 12 12 of of ADP g732d794p3k 12 13 these these DET g732d794p3k 12 14 behaviors behavior NOUN g732d794p3k 12 15 . . PUNCT g732d794p3k 13 1 by by ADP g732d794p3k 13 2 dampening dampen VERB g732d794p3k 13 3 locomotion locomotion NOUN g732d794p3k 13 4 and and CCONJ g732d794p3k 13 5 blood blood NOUN g732d794p3k 13 6 - - PUNCT g732d794p3k 13 7 feeding feeding NOUN g732d794p3k 13 8 , , PUNCT g732d794p3k 13 9 indirect indirect ADJ g732d794p3k 13 10 determinants determinant NOUN g732d794p3k 13 11 of of ADP g732d794p3k 13 12 vectorial vectorial ADJ g732d794p3k 13 13 capacity capacity NOUN g732d794p3k 13 14 , , PUNCT g732d794p3k 13 15 transmission transmission NOUN g732d794p3k 13 16 and and CCONJ g732d794p3k 13 17 burden burden NOUN g732d794p3k 13 18 of of ADP g732d794p3k 13 19 vbds vbds NOUN g732d794p3k 13 20 could could AUX g732d794p3k 13 21 effectively effectively ADV g732d794p3k 13 22 be be AUX g732d794p3k 13 23 reduced reduce VERB g732d794p3k 13 24 . . PUNCT g732d794p3k 14 1 considering consider VERB g732d794p3k 14 2 these these DET g732d794p3k 14 3 positive positive ADJ g732d794p3k 14 4 global global ADJ g732d794p3k 14 5 health health NOUN g732d794p3k 14 6 implications implication NOUN g732d794p3k 14 7 , , PUNCT g732d794p3k 14 8 the the DET g732d794p3k 14 9 serotonergic serotonergic NOUN g732d794p3k 14 10 system system NOUN g732d794p3k 14 11 is be AUX g732d794p3k 14 12 a a DET g732d794p3k 14 13 compelling compelling ADJ g732d794p3k 14 14 target target NOUN g732d794p3k 14 15 for for ADP g732d794p3k 14 16 the the DET g732d794p3k 14 17 novel novel ADJ g732d794p3k 14 18 insecticide insecticide PROPN g732d794p3k 14 19 pipeline pipeline PROPN g732d794p3k 14 20 . . PUNCT