id sid tid token lemma pos fx719k4437n 1 1 selective selective ADJ fx719k4437n 1 2 delivery delivery NOUN fx719k4437n 1 3 of of ADP fx719k4437n 1 4 molecular molecular ADJ fx719k4437n 1 5 cargo cargo NOUN fx719k4437n 1 6 in in ADP fx719k4437n 1 7 complex complex ADJ fx719k4437n 1 8 biological biological ADJ fx719k4437n 1 9 systems system NOUN fx719k4437n 1 10 is be AUX fx719k4437n 1 11 a a DET fx719k4437n 1 12 major major ADJ fx719k4437n 1 13 unsolved unsolved ADJ fx719k4437n 1 14 problem problem NOUN fx719k4437n 1 15 that that PRON fx719k4437n 1 16 impacts impact VERB fx719k4437n 1 17 many many ADJ fx719k4437n 1 18 fields field NOUN fx719k4437n 1 19 of of ADP fx719k4437n 1 20 biomedical biomedical ADJ fx719k4437n 1 21 research research NOUN fx719k4437n 1 22 and and CCONJ fx719k4437n 1 23 technology technology NOUN fx719k4437n 1 24 . . PUNCT fx719k4437n 2 1 in in ADP fx719k4437n 2 2 addition addition NOUN fx719k4437n 2 3 to to ADP fx719k4437n 2 4 the the DET fx719k4437n 2 5 complexity complexity NOUN fx719k4437n 2 6 of of ADP fx719k4437n 2 7 finding find VERB fx719k4437n 2 8 the the DET fx719k4437n 2 9 correct correct ADJ fx719k4437n 2 10 target target NOUN fx719k4437n 2 11 in in ADP fx719k4437n 2 12 a a DET fx719k4437n 2 13 living live VERB fx719k4437n 2 14 animal animal NOUN fx719k4437n 2 15 , , PUNCT fx719k4437n 2 16 there there PRON fx719k4437n 2 17 is be VERB fx719k4437n 2 18 the the DET fx719k4437n 2 19 challenge challenge NOUN fx719k4437n 2 20 of of ADP fx719k4437n 2 21 transporting transport VERB fx719k4437n 2 22 molecular molecular ADJ fx719k4437n 2 23 cargo cargo NOUN fx719k4437n 2 24 across across ADP fx719k4437n 2 25 the the DET fx719k4437n 2 26 plasma plasma NOUN fx719k4437n 2 27 membrane membrane NOUN fx719k4437n 2 28 of of ADP fx719k4437n 2 29 a a DET fx719k4437n 2 30 living live VERB fx719k4437n 2 31 cell cell NOUN fx719k4437n 2 32 . . PUNCT fx719k4437n 3 1 this this DET fx719k4437n 3 2 thesis thesis NOUN fx719k4437n 3 3 describes describe VERB fx719k4437n 3 4 several several ADJ fx719k4437n 3 5 methods method NOUN fx719k4437n 3 6 to to PART fx719k4437n 3 7 deliver deliver VERB fx719k4437n 3 8 molecular molecular ADJ fx719k4437n 3 9 cargo cargo NOUN fx719k4437n 3 10 to to ADP fx719k4437n 3 11 specific specific ADJ fx719k4437n 3 12 biological biological ADJ fx719k4437n 3 13 sites site NOUN fx719k4437n 3 14 by by ADP fx719k4437n 3 15 targeting target VERB fx719k4437n 3 16 structures structure NOUN fx719k4437n 3 17 such such ADJ fx719k4437n 3 18 as as ADP fx719k4437n 3 19 anionic anionic ADJ fx719k4437n 3 20 phospholipids phospholipid NOUN fx719k4437n 3 21 . . PUNCT fx719k4437n 4 1 once once SCONJ fx719k4437n 4 2 class class NOUN fx719k4437n 4 3 of of ADP fx719k4437n 4 4 these these DET fx719k4437n 4 5 conjugates conjugate NOUN fx719k4437n 4 6 can can AUX fx719k4437n 4 7 enter enter VERB fx719k4437n 4 8 into into ADP fx719k4437n 4 9 living live VERB fx719k4437n 4 10 cells cell NOUN fx719k4437n 4 11 via via ADP fx719k4437n 4 12 endocytic endocytic ADJ fx719k4437n 4 13 uptake uptake NOUN fx719k4437n 4 14 while while SCONJ fx719k4437n 4 15 another another PRON fx719k4437n 4 16 can can AUX fx719k4437n 4 17 be be AUX fx719k4437n 4 18 transported transport VERB fx719k4437n 4 19 directly directly ADV fx719k4437n 4 20 across across ADP fx719k4437n 4 21 the the DET fx719k4437n 4 22 plasma plasma NOUN fx719k4437n 4 23 membrane membrane NOUN fx719k4437n 4 24 by by ADP fx719k4437n 4 25 phospholipid phospholipid NOUN fx719k4437n 4 26 transloases transloase NOUN fx719k4437n 4 27 . . PUNCT fx719k4437n 5 1 while while SCONJ fx719k4437n 5 2 the the DET fx719k4437n 5 3 efficacy efficacy NOUN fx719k4437n 5 4 of of ADP fx719k4437n 5 5 a a DET fx719k4437n 5 6 therapeutic therapeutic ADJ fx719k4437n 5 7 aget aget NOUN fx719k4437n 5 8 can can AUX fx719k4437n 5 9 be be AUX fx719k4437n 5 10 monitored monitor VERB fx719k4437n 5 11 by by ADP fx719k4437n 5 12 assaying assay VERB fx719k4437n 5 13 a a DET fx719k4437n 5 14 physiological physiological ADJ fx719k4437n 5 15 response response NOUN fx719k4437n 5 16 , , PUNCT fx719k4437n 5 17 this this PRON fx719k4437n 5 18 may may AUX fx719k4437n 5 19 be be AUX fx719k4437n 5 20 time time NOUN fx719k4437n 5 21 consuming consume VERB fx719k4437n 5 22 and and CCONJ fx719k4437n 5 23 require require VERB fx719k4437n 5 24 large large ADJ fx719k4437n 5 25 quantities quantity NOUN fx719k4437n 5 26 of of ADP fx719k4437n 5 27 resources resource NOUN fx719k4437n 5 28 . . PUNCT fx719k4437n 6 1 fluorescence fluorescence ADJ fx719k4437n 6 2 imaging imaging NOUN fx719k4437n 6 3 provides provide VERB fx719k4437n 6 4 a a DET fx719k4437n 6 5 powerful powerful ADJ fx719k4437n 6 6 and and CCONJ fx719k4437n 6 7 convenient convenient ADJ fx719k4437n 6 8 method method NOUN fx719k4437n 6 9 to to PART fx719k4437n 6 10 monitor monitor VERB fx719k4437n 6 11 biological biological ADJ fx719k4437n 6 12 systems system NOUN fx719k4437n 6 13 both both CCONJ fx719k4437n 6 14 in in ADP fx719k4437n 6 15 vitro vitro X fx719k4437n 6 16 and and CCONJ fx719k4437n 6 17 in in ADP fx719k4437n 6 18 vivo vivo NOUN fx719k4437n 6 19 in in ADP fx719k4437n 6 20 real real ADJ fx719k4437n 6 21 time time NOUN fx719k4437n 6 22 . . PUNCT fx719k4437n 7 1 therefore therefore ADV fx719k4437n 7 2 , , PUNCT fx719k4437n 7 3 there there PRON fx719k4437n 7 4 is be VERB fx719k4437n 7 5 a a DET fx719k4437n 7 6 need need NOUN fx719k4437n 7 7 for for ADP fx719k4437n 7 8 fluorescent fluorescent ADJ fx719k4437n 7 9 dyes dye NOUN fx719k4437n 7 10 that that PRON fx719k4437n 7 11 are be AUX fx719k4437n 7 12 brighter bright ADJ fx719k4437n 7 13 , , PUNCT fx719k4437n 7 14 more more ADV fx719k4437n 7 15 photostable photostable ADJ fx719k4437n 7 16 , , PUNCT fx719k4437n 7 17 and and CCONJ fx719k4437n 7 18 robust robust ADJ fx719k4437n 7 19 in in ADP fx719k4437n 7 20 biological biological ADJ fx719k4437n 7 21 systems system NOUN fx719k4437n 7 22 . . PUNCT fx719k4437n 8 1 the the DET fx719k4437n 8 2 dye dye NOUN fx719k4437n 8 3 described describe VERB fx719k4437n 8 4 here here ADV fx719k4437n 8 5 , , PUNCT fx719k4437n 8 6 the the DET fx719k4437n 8 7 squaraine squaraine ADJ fx719k4437n 8 8 rotaxane rotaxane NOUN fx719k4437n 8 9 , , PUNCT fx719k4437n 8 10 shows show VERB fx719k4437n 8 11 significantly significantly ADV fx719k4437n 8 12 greater great ADJ fx719k4437n 8 13 photostability photostability NOUN fx719k4437n 8 14 and and CCONJ fx719k4437n 8 15 resistance resistance NOUN fx719k4437n 8 16 to to ADP fx719k4437n 8 17 degradation degradation NOUN fx719k4437n 8 18 in in ADP fx719k4437n 8 19 biological biological ADJ fx719k4437n 8 20 systems system NOUN fx719k4437n 8 21 as as SCONJ fx719k4437n 8 22 compared compare VERB fx719k4437n 8 23 to to ADP fx719k4437n 8 24 conventional conventional ADJ fx719k4437n 8 25 fluorescent fluorescent NOUN fx719k4437n 8 26 dyes dye NOUN fx719k4437n 8 27 . . PUNCT fx719k4437n 9 1 also also ADV fx719k4437n 9 2 , , PUNCT fx719k4437n 9 3 it it PRON fx719k4437n 9 4 can can AUX fx719k4437n 9 5 be be AUX fx719k4437n 9 6 chemically chemically ADV fx719k4437n 9 7 modified modify VERB fx719k4437n 9 8 to to PART fx719k4437n 9 9 localize localize VERB fx719k4437n 9 10 to to ADP fx719k4437n 9 11 different different ADJ fx719k4437n 9 12 subcellular subcellular ADJ fx719k4437n 9 13 targets target NOUN fx719k4437n 9 14 . . PUNCT