id sid tid token lemma pos fq977s7887j 1 1 pancreatic pancreatic ADJ fq977s7887j 1 2 ductal ductal NOUN fq977s7887j 1 3 adenocarcinoma adenocarcinoma NOUN fq977s7887j 1 4 ( ( PUNCT fq977s7887j 1 5 pdac pdac PROPN fq977s7887j 1 6 ) ) PUNCT fq977s7887j 1 7 has have VERB fq977s7887j 1 8 a a DET fq977s7887j 1 9 5 5 NUM fq977s7887j 1 10 - - PUNCT fq977s7887j 1 11 year year NOUN fq977s7887j 1 12 survival survival NOUN fq977s7887j 1 13 rate rate NOUN fq977s7887j 1 14 of of ADP fq977s7887j 1 15 8 8 NUM fq977s7887j 1 16 % % NOUN fq977s7887j 1 17 . . PUNCT fq977s7887j 2 1 this this DET fq977s7887j 2 2 dismal dismal ADJ fq977s7887j 2 3 outlook outlook NOUN fq977s7887j 2 4 is be AUX fq977s7887j 2 5 largely largely ADV fq977s7887j 2 6 due due ADJ fq977s7887j 2 7 to to ADP fq977s7887j 2 8 the the DET fq977s7887j 2 9 inability inability NOUN fq977s7887j 2 10 to to PART fq977s7887j 2 11 diagnose diagnose VERB fq977s7887j 2 12 pdac pdac NOUN fq977s7887j 2 13 before before SCONJ fq977s7887j 2 14 metastasis metastasis NOUN fq977s7887j 2 15 occurs occur VERB fq977s7887j 2 16 . . PUNCT fq977s7887j 3 1 with with ADP fq977s7887j 3 2 52 52 NUM fq977s7887j 3 3 % % NOUN fq977s7887j 3 4 of of ADP fq977s7887j 3 5 patients patient NOUN fq977s7887j 3 6 being be AUX fq977s7887j 3 7 diagnosed diagnose VERB fq977s7887j 3 8 at at ADP fq977s7887j 3 9 metastatic metastatic ADJ fq977s7887j 3 10 stage stage NOUN fq977s7887j 3 11 , , PUNCT fq977s7887j 3 12 there there PRON fq977s7887j 3 13 is be VERB fq977s7887j 3 14 a a DET fq977s7887j 3 15 critical critical ADJ fq977s7887j 3 16 need need NOUN fq977s7887j 3 17 to to PART fq977s7887j 3 18 better well ADV fq977s7887j 3 19 understand understand VERB fq977s7887j 3 20 the the DET fq977s7887j 3 21 mechanisms mechanism NOUN fq977s7887j 3 22 of of ADP fq977s7887j 3 23 metastatic metastatic ADJ fq977s7887j 3 24 progression progression NOUN fq977s7887j 3 25 in in ADP fq977s7887j 3 26 this this DET fq977s7887j 3 27 disease disease NOUN fq977s7887j 3 28 . . PUNCT fq977s7887j 4 1 one one NUM fq977s7887j 4 2 hallmark hallmark NOUN fq977s7887j 4 3 of of ADP fq977s7887j 4 4 pdac pdac PROPN fq977s7887j 4 5 is be AUX fq977s7887j 4 6 inflammation inflammation NOUN fq977s7887j 4 7 . . PUNCT fq977s7887j 5 1 while while SCONJ fq977s7887j 5 2 many many ADJ fq977s7887j 5 3 studies study NOUN fq977s7887j 5 4 have have AUX fq977s7887j 5 5 focused focus VERB fq977s7887j 5 6 on on ADP fq977s7887j 5 7 elucidating elucidate VERB fq977s7887j 5 8 the the DET fq977s7887j 5 9 mechanisms mechanism NOUN fq977s7887j 5 10 by by ADP fq977s7887j 5 11 which which PRON fq977s7887j 5 12 inflammation inflammation NOUN fq977s7887j 5 13 drives drive VERB fq977s7887j 5 14 pdac pdac NOUN fq977s7887j 5 15 progression progression NOUN fq977s7887j 5 16 , , PUNCT fq977s7887j 5 17 few few ADJ fq977s7887j 5 18 have have AUX fq977s7887j 5 19 focused focus VERB fq977s7887j 5 20 on on ADP fq977s7887j 5 21 the the DET fq977s7887j 5 22 role role NOUN fq977s7887j 5 23 inflammation inflammation NOUN fq977s7887j 5 24 plays play VERB fq977s7887j 5 25 in in ADP fq977s7887j 5 26 metastasis metastasis NOUN fq977s7887j 5 27 . . PUNCT fq977s7887j 6 1 using use VERB fq977s7887j 6 2 a a DET fq977s7887j 6 3 novel novel ADJ fq977s7887j 6 4 inflammation inflammation NOUN fq977s7887j 6 5 - - PUNCT fq977s7887j 6 6 driven drive VERB fq977s7887j 6 7 mouse mouse NOUN fq977s7887j 6 8 model model NOUN fq977s7887j 6 9 of of ADP fq977s7887j 6 10 pdac pdac NOUN fq977s7887j 6 11 , , PUNCT fq977s7887j 6 12 a a DET fq977s7887j 6 13 subset subset NOUN fq977s7887j 6 14 of of ADP fq977s7887j 6 15 genes gene NOUN fq977s7887j 6 16 was be AUX fq977s7887j 6 17 uncovered uncover VERB fq977s7887j 6 18 that that SCONJ fq977s7887j 6 19 not not PART fq977s7887j 6 20 only only ADV fq977s7887j 6 21 were be AUX fq977s7887j 6 22 regulated regulate VERB fq977s7887j 6 23 by by ADP fq977s7887j 6 24 increased increase VERB fq977s7887j 6 25 inflammation inflammation NOUN fq977s7887j 6 26 , , PUNCT fq977s7887j 6 27 but but CCONJ fq977s7887j 6 28 also also ADV fq977s7887j 6 29 correlated correlate VERB fq977s7887j 6 30 with with ADP fq977s7887j 6 31 poor poor ADJ fq977s7887j 6 32 pdac pdac NOUN fq977s7887j 6 33 patient patient NOUN fq977s7887j 6 34 prognosis prognosis NOUN fq977s7887j 6 35 . . PUNCT fq977s7887j 7 1 the the DET fq977s7887j 7 2 overall overall ADJ fq977s7887j 7 3 goal goal NOUN fq977s7887j 7 4 of of ADP fq977s7887j 7 5 this this DET fq977s7887j 7 6 research research NOUN fq977s7887j 7 7 was be AUX fq977s7887j 7 8 to to PART fq977s7887j 7 9 investigate investigate VERB fq977s7887j 7 10 the the DET fq977s7887j 7 11 role role NOUN fq977s7887j 7 12 and and CCONJ fq977s7887j 7 13 regulation regulation NOUN fq977s7887j 7 14 of of ADP fq977s7887j 7 15 one one NUM fq977s7887j 7 16 of of ADP fq977s7887j 7 17 the the DET fq977s7887j 7 18 genes gene NOUN fq977s7887j 7 19 found find VERB fq977s7887j 7 20 in in ADP fq977s7887j 7 21 this this DET fq977s7887j 7 22 subset subset NOUN fq977s7887j 7 23 that that PRON fq977s7887j 7 24 is be AUX fq977s7887j 7 25 involved involve VERB fq977s7887j 7 26 in in ADP fq977s7887j 7 27 metastatic metastatic ADJ fq977s7887j 7 28 progression progression NOUN fq977s7887j 7 29 , , PUNCT fq977s7887j 7 30 namely namely ADV fq977s7887j 7 31 , , PUNCT fq977s7887j 7 32 metastasis metastasis NOUN fq977s7887j 7 33 suppressor suppressor NOUN fq977s7887j 7 34 protein protein NOUN fq977s7887j 7 35 1 1 NUM fq977s7887j 7 36 ( ( PUNCT fq977s7887j 7 37 mtss1 mtss1 PROPN fq977s7887j 7 38 ) ) PUNCT fq977s7887j 7 39 . . PUNCT fq977s7887j 8 1 it it PRON fq977s7887j 8 2 was be AUX fq977s7887j 8 3 established establish VERB fq977s7887j 8 4 that that SCONJ fq977s7887j 8 5 loss loss NOUN fq977s7887j 8 6 of of ADP fq977s7887j 8 7 mtss1 mtss1 PROPN fq977s7887j 8 8 leads lead NOUN fq977s7887j 8 9 to to ADP fq977s7887j 8 10 increased increase VERB fq977s7887j 8 11 invasion invasion NOUN fq977s7887j 8 12 and and CCONJ fq977s7887j 8 13 migration migration NOUN fq977s7887j 8 14 in in ADP fq977s7887j 8 15 pdac pdac NOUN fq977s7887j 8 16 cells cell NOUN fq977s7887j 8 17 . . PUNCT fq977s7887j 9 1 moreover moreover ADV fq977s7887j 9 2 , , PUNCT fq977s7887j 9 3 cells cell NOUN fq977s7887j 9 4 treated treat VERB fq977s7887j 9 5 with with ADP fq977s7887j 9 6 cancer cancer NOUN fq977s7887j 9 7 - - PUNCT fq977s7887j 9 8 associated associate VERB fq977s7887j 9 9 fibroblast fibroblast NOUN fq977s7887j 9 10 - - PUNCT fq977s7887j 9 11 conditioned condition VERB fq977s7887j 9 12 media medium NOUN fq977s7887j 9 13 also also ADV fq977s7887j 9 14 have have AUX fq977s7887j 9 15 increased increase VERB fq977s7887j 9 16 metastatic metastatic ADJ fq977s7887j 9 17 potential potential NOUN fq977s7887j 9 18 , , PUNCT fq977s7887j 9 19 which which PRON fq977s7887j 9 20 is be AUX fq977s7887j 9 21 augmented augment VERB fq977s7887j 9 22 by by ADP fq977s7887j 9 23 mtss1 mtss1 ADJ fq977s7887j 9 24 loss loss NOUN fq977s7887j 9 25 . . PUNCT fq977s7887j 10 1 additionally additionally ADV fq977s7887j 10 2 , , PUNCT fq977s7887j 10 3 overexpression overexpression NOUN fq977s7887j 10 4 of of ADP fq977s7887j 10 5 mtss1 mtss1 ADJ fq977s7887j 10 6 in in ADP fq977s7887j 10 7 pdac pdac NOUN fq977s7887j 10 8 cells cell NOUN fq977s7887j 10 9 leads lead VERB fq977s7887j 10 10 to to ADP fq977s7887j 10 11 a a DET fq977s7887j 10 12 loss loss NOUN fq977s7887j 10 13 of of ADP fq977s7887j 10 14 migratory migratory ADJ fq977s7887j 10 15 potential potential NOUN fq977s7887j 10 16 in in ADP fq977s7887j 10 17 vitro vitro X fq977s7887j 10 18 and and CCONJ fq977s7887j 10 19 an an DET fq977s7887j 10 20 increase increase NOUN fq977s7887j 10 21 in in ADP fq977s7887j 10 22 overall overall ADJ fq977s7887j 10 23 survival survival NOUN fq977s7887j 10 24 in in ADP fq977s7887j 10 25 vivo vivo PROPN fq977s7887j 10 26 . . PUNCT fq977s7887j 11 1 furthermore furthermore ADV fq977s7887j 11 2 , , PUNCT fq977s7887j 11 3 a a DET fq977s7887j 11 4 novel novel ADJ fq977s7887j 11 5 regulatory regulatory ADJ fq977s7887j 11 6 mechanism mechanism NOUN fq977s7887j 11 7 for for ADP fq977s7887j 11 8 the the DET fq977s7887j 11 9 stabilization stabilization NOUN fq977s7887j 11 10 of of ADP fq977s7887j 11 11 mtss1 mtss1 PROPN fq977s7887j 11 12 via via ADP fq977s7887j 11 13 the the DET fq977s7887j 11 14 tumor tumor NOUN fq977s7887j 11 15 suppressor suppressor NOUN fq977s7887j 11 16 protein protein NOUN fq977s7887j 11 17 , , PUNCT fq977s7887j 11 18 phosphatase phosphatase NOUN fq977s7887j 11 19 and and CCONJ fq977s7887j 11 20 tensin tensin PROPN fq977s7887j 11 21 homolog homolog PROPN fq977s7887j 11 22 deleted delete VERB fq977s7887j 11 23 on on ADP fq977s7887j 11 24 chromosome chromosome NOUN fq977s7887j 11 25 10 10 NUM fq977s7887j 11 26 ( ( PUNCT fq977s7887j 11 27 pten pten NOUN fq977s7887j 11 28 ) ) PUNCT fq977s7887j 11 29 was be AUX fq977s7887j 11 30 discovered discover VERB fq977s7887j 11 31 . . PUNCT fq977s7887j 12 1 the the DET fq977s7887j 12 2 data datum NOUN fq977s7887j 12 3 show show VERB fq977s7887j 12 4 that that SCONJ fq977s7887j 12 5 pten pten NOUN fq977s7887j 12 6 loss loss NOUN fq977s7887j 12 7 results result NOUN fq977s7887j 12 8 in in ADP fq977s7887j 12 9 increased increase VERB fq977s7887j 12 10 metastatic metastatic ADJ fq977s7887j 12 11 potential potential NOUN fq977s7887j 12 12 and and CCONJ fq977s7887j 12 13 decreased decrease VERB fq977s7887j 12 14 mtss1 mtss1 ADJ fq977s7887j 12 15 expression expression NOUN fq977s7887j 12 16 in in ADP fq977s7887j 12 17 vitro vitro X fq977s7887j 12 18 . . PUNCT fq977s7887j 13 1 furthermore furthermore ADV fq977s7887j 13 2 , , PUNCT fq977s7887j 13 3 it it PRON fq977s7887j 13 4 was be AUX fq977s7887j 13 5 found find VERB fq977s7887j 13 6 that that SCONJ fq977s7887j 13 7 ectopic ectopic ADJ fq977s7887j 13 8 mtss1 mtss1 ADJ fq977s7887j 13 9 expression expression NOUN fq977s7887j 13 10 rescues rescue VERB fq977s7887j 13 11 this this DET fq977s7887j 13 12 effect effect NOUN fq977s7887j 13 13 . . PUNCT fq977s7887j 14 1 additionally additionally ADV fq977s7887j 14 2 , , PUNCT fq977s7887j 14 3 it it PRON fq977s7887j 14 4 was be AUX fq977s7887j 14 5 demonstrated demonstrate VERB fq977s7887j 14 6 that that SCONJ fq977s7887j 14 7 pten pten NOUN fq977s7887j 14 8 forms form VERB fq977s7887j 14 9 a a DET fq977s7887j 14 10 complex complex NOUN fq977s7887j 14 11 with with ADP fq977s7887j 14 12 mtss1 mtss1 PROPN fq977s7887j 14 13 , , PUNCT fq977s7887j 14 14 stabilizing stabilize VERB fq977s7887j 14 15 it it PRON fq977s7887j 14 16 from from ADP fq977s7887j 14 17 proteasomal proteasomal ADJ fq977s7887j 14 18 degradation degradation NOUN fq977s7887j 14 19 . . PUNCT fq977s7887j 15 1 finally finally ADV fq977s7887j 15 2 , , PUNCT fq977s7887j 15 3 it it PRON fq977s7887j 15 4 was be AUX fq977s7887j 15 5 shown show VERB fq977s7887j 15 6 that that SCONJ fq977s7887j 15 7 the the DET fq977s7887j 15 8 inflammatory inflammatory ADJ fq977s7887j 15 9 tumor tumor NOUN fq977s7887j 15 10 microenvironment microenvironment NOUN fq977s7887j 15 11 , , PUNCT fq977s7887j 15 12 which which PRON fq977s7887j 15 13 makes make VERB fq977s7887j 15 14 up up ADP fq977s7887j 15 15 over over ADP fq977s7887j 15 16 90 90 NUM fq977s7887j 15 17 % % NOUN fq977s7887j 15 18 of of ADP fq977s7887j 15 19 pdac pdac PROPN fq977s7887j 15 20 tumor tumor NOUN fq977s7887j 15 21 bulk bulk NOUN fq977s7887j 15 22 , , PUNCT fq977s7887j 15 23 is be AUX fq977s7887j 15 24 capable capable ADJ fq977s7887j 15 25 of of ADP fq977s7887j 15 26 downregulating downregulate VERB fq977s7887j 15 27 pten pten NOUN fq977s7887j 15 28 expression expression NOUN fq977s7887j 15 29 , , PUNCT fq977s7887j 15 30 potentially potentially ADV fq977s7887j 15 31 uncovering uncover VERB fq977s7887j 15 32 a a DET fq977s7887j 15 33 novel novel ADJ fq977s7887j 15 34 extrinsic extrinsic ADJ fq977s7887j 15 35 mechanism mechanism NOUN fq977s7887j 15 36 of of ADP fq977s7887j 15 37 mtss1 mtss1 ADJ fq977s7887j 15 38 regulation regulation NOUN fq977s7887j 15 39 . . PUNCT fq977s7887j 16 1 collectively collectively ADV fq977s7887j 16 2 , , PUNCT fq977s7887j 16 3 these these DET fq977s7887j 16 4 data datum NOUN fq977s7887j 16 5 offer offer VERB fq977s7887j 16 6 both both DET fq977s7887j 16 7 new new ADJ fq977s7887j 16 8 insight insight NOUN fq977s7887j 16 9 into into ADP fq977s7887j 16 10 the the DET fq977s7887j 16 11 role role NOUN fq977s7887j 16 12 and and CCONJ fq977s7887j 16 13 regulation regulation NOUN fq977s7887j 16 14 of of ADP fq977s7887j 16 15 mtss1 mtss1 NOUN fq977s7887j 16 16 in in ADP fq977s7887j 16 17 suppressing suppress VERB fq977s7887j 16 18 tumor tumor NOUN fq977s7887j 16 19 cell cell NOUN fq977s7887j 16 20 invasion invasion NOUN fq977s7887j 16 21 and and CCONJ fq977s7887j 16 22 migration migration NOUN fq977s7887j 16 23 as as ADV fq977s7887j 16 24 well well ADV fq977s7887j 16 25 as as ADP fq977s7887j 16 26 a a DET fq977s7887j 16 27 different different ADJ fq977s7887j 16 28 glimpse glimpse NOUN fq977s7887j 16 29 as as ADP fq977s7887j 16 30 to to ADP fq977s7887j 16 31 what what PRON fq977s7887j 16 32 molecular molecular ADJ fq977s7887j 16 33 mechanisms mechanism NOUN fq977s7887j 16 34 could could AUX fq977s7887j 16 35 be be AUX fq977s7887j 16 36 leading lead VERB fq977s7887j 16 37 to to ADP fq977s7887j 16 38 early early ADJ fq977s7887j 16 39 cell cell NOUN fq977s7887j 16 40 dissemination dissemination NOUN fq977s7887j 16 41 in in ADP fq977s7887j 16 42 pdac pdac PROPN fq977s7887j 16 43 . . PUNCT