id	sid	tid	token	lemma	pos
fn106w9490b	1	1	morphogenesis	morphogenesis	NOUN
fn106w9490b	1	2	and	and	CCONJ
fn106w9490b	1	3	differentiation	differentiation	NOUN
fn106w9490b	1	4	of	of	ADP
fn106w9490b	1	5	internal	internal	ADJ
fn106w9490b	1	6	epithelial	epithelial	ADJ
fn106w9490b	1	7	organs	organ	NOUN
fn106w9490b	1	8	is	be	AUX
fn106w9490b	1	9	dependent	dependent	ADJ
fn106w9490b	1	10	on	on	ADP
fn106w9490b	1	11	various	various	ADJ
fn106w9490b	1	12	processes	process	NOUN
fn106w9490b	1	13	including	include	VERB
fn106w9490b	1	14	cell	cell	NOUN
fn106w9490b	1	15	-	-	PUNCT
fn106w9490b	1	16	cell	cell	NOUN
fn106w9490b	1	17	and	and	CCONJ
fn106w9490b	1	18	cell	cell	NOUN
fn106w9490b	1	19	-	-	PUNCT
fn106w9490b	1	20	matrix	matrix	NOUN
fn106w9490b	1	21	interactions	interaction	NOUN
fn106w9490b	1	22	,	,	PUNCT
fn106w9490b	1	23	cell	cell	NOUN
fn106w9490b	1	24	polarity	polarity	NOUN
fn106w9490b	1	25	and	and	CCONJ
fn106w9490b	1	26	the	the	DET
fn106w9490b	1	27	interplay	interplay	NOUN
fn106w9490b	1	28	of	of	ADP
fn106w9490b	1	29	cell	cell	NOUN
fn106w9490b	1	30	survival	survival	NOUN
fn106w9490b	1	31	and	and	CCONJ
fn106w9490b	1	32	cell	cell	NOUN
fn106w9490b	1	33	death	death	NOUN
fn106w9490b	1	34	pathways	pathway	NOUN
fn106w9490b	1	35	.	.	PUNCT
fn106w9490b	2	1	epithelial	epithelial	ADJ
fn106w9490b	2	2	cancer	cancer	NOUN
fn106w9490b	2	3	progression	progression	NOUN
fn106w9490b	2	4	is	be	AUX
fn106w9490b	2	5	often	often	ADV
fn106w9490b	2	6	accompanied	accompany	VERB
fn106w9490b	2	7	by	by	ADP
fn106w9490b	2	8	the	the	DET
fn106w9490b	2	9	disruption	disruption	NOUN
fn106w9490b	2	10	of	of	ADP
fn106w9490b	2	11	epithelial	epithelial	ADJ
fn106w9490b	2	12	gland	gland	NOUN
fn106w9490b	2	13	architecture	architecture	NOUN
fn106w9490b	2	14	,	,	PUNCT
fn106w9490b	2	15	although	although	SCONJ
fn106w9490b	2	16	little	little	ADJ
fn106w9490b	2	17	is	be	AUX
fn106w9490b	2	18	understood	understand	VERB
fn106w9490b	2	19	about	about	ADP
fn106w9490b	2	20	the	the	DET
fn106w9490b	2	21	signaling	signal	VERB
fn106w9490b	2	22	pathways	pathway	NOUN
fn106w9490b	2	23	and	and	CCONJ
fn106w9490b	2	24	cellular	cellular	ADJ
fn106w9490b	2	25	processes	process	NOUN
fn106w9490b	2	26	involved	involve	VERB
fn106w9490b	2	27	.	.	PUNCT
fn106w9490b	3	1	however	however	ADV
fn106w9490b	3	2	,	,	PUNCT
fn106w9490b	3	3	various	various	ADJ
fn106w9490b	3	4	oncogenes	oncogene	NOUN
fn106w9490b	3	5	have	have	AUX
fn106w9490b	3	6	been	be	AUX
fn106w9490b	3	7	shown	show	VERB
fn106w9490b	3	8	to	to	PART
fn106w9490b	3	9	affect	affect	VERB
fn106w9490b	3	10	internal	internal	ADJ
fn106w9490b	3	11	epithelial	epithelial	ADJ
fn106w9490b	3	12	organ	organ	NOUN
fn106w9490b	3	13	development	development	NOUN
fn106w9490b	3	14	and	and	CCONJ
fn106w9490b	3	15	polarization	polarization	NOUN
fn106w9490b	3	16	by	by	ADP
fn106w9490b	3	17	deregulating	deregulate	VERB
fn106w9490b	3	18	one	one	NUM
fn106w9490b	3	19	or	or	CCONJ
fn106w9490b	3	20	more	more	ADJ
fn106w9490b	3	21	of	of	ADP
fn106w9490b	3	22	the	the	DET
fn106w9490b	3	23	aforementioned	aforementioned	ADJ
fn106w9490b	3	24	cellular	cellular	ADJ
fn106w9490b	3	25	processes	process	NOUN
fn106w9490b	3	26	described	describe	VERB
fn106w9490b	3	27	above	above	ADV
fn106w9490b	3	28	.	.	PUNCT
fn106w9490b	4	1	this	this	DET
fn106w9490b	4	2	study	study	NOUN
fn106w9490b	4	3	describes	describe	VERB
fn106w9490b	4	4	a	a	DET
fn106w9490b	4	5	novel	novel	ADJ
fn106w9490b	4	6	role	role	NOUN
fn106w9490b	4	7	for	for	ADP
fn106w9490b	4	8	the	the	DET
fn106w9490b	4	9	arf6	arf6	PROPN
fn106w9490b	4	10	gtpase	gtpase	NOUN
fn106w9490b	4	11	in	in	ADP
fn106w9490b	4	12	the	the	DET
fn106w9490b	4	13	regulation	regulation	NOUN
fn106w9490b	4	14	of	of	ADP
fn106w9490b	4	15	epithelial	epithelial	ADJ
fn106w9490b	4	16	architecture	architecture	NOUN
fn106w9490b	4	17	and	and	CCONJ
fn106w9490b	4	18	gland	gland	NOUN
fn106w9490b	4	19	development	development	NOUN
fn106w9490b	4	20	.	.	PUNCT
fn106w9490b	5	1	arf6	arf6	PROPN
fn106w9490b	5	2	functions	function	NOUN
fn106w9490b	5	3	downstream	downstream	ADV
fn106w9490b	5	4	of	of	ADP
fn106w9490b	5	5	src	src	NOUN
fn106w9490b	5	6	,	,	PUNCT
fn106w9490b	5	7	the	the	DET
fn106w9490b	5	8	activation	activation	NOUN
fn106w9490b	5	9	of	of	ADP
fn106w9490b	5	10	which	which	PRON
fn106w9490b	5	11	leads	lead	VERB
fn106w9490b	5	12	to	to	ADP
fn106w9490b	5	13	the	the	DET
fn106w9490b	5	14	targeting	targeting	NOUN
fn106w9490b	5	15	of	of	ADP
fn106w9490b	5	16	the	the	DET
fn106w9490b	5	17	cell	cell	NOUN
fn106w9490b	5	18	-	-	PUNCT
fn106w9490b	5	19	cell	cell	NOUN
fn106w9490b	5	20	adhesion	adhesion	NOUN
fn106w9490b	5	21	molecule	molecule	NOUN
fn106w9490b	5	22	,	,	PUNCT
fn106w9490b	5	23	e	e	NOUN
fn106w9490b	5	24	-	-	NOUN
fn106w9490b	5	25	cadherin	cadherin	NOUN
fn106w9490b	5	26	,	,	PUNCT
fn106w9490b	5	27	to	to	ADP
fn106w9490b	5	28	the	the	DET
fn106w9490b	5	29	lysosome	lysosome	NOUN
fn106w9490b	5	30	.	.	PUNCT
fn106w9490b	6	1	by	by	ADP
fn106w9490b	6	2	use	use	NOUN
fn106w9490b	6	3	of	of	ADP
fn106w9490b	6	4	three	three	NUM
fn106w9490b	6	5	dimensional	dimensional	ADJ
fn106w9490b	6	6	cell	cell	NOUN
fn106w9490b	6	7	-	-	PUNCT
fn106w9490b	6	8	culture	culture	NOUN
fn106w9490b	6	9	,	,	PUNCT
fn106w9490b	6	10	the	the	DET
fn106w9490b	6	11	role	role	NOUN
fn106w9490b	6	12	of	of	ADP
fn106w9490b	6	13	arf6	arf6	PROPN
fn106w9490b	6	14	in	in	ADP
fn106w9490b	6	15	the	the	DET
fn106w9490b	6	16	development	development	NOUN
fn106w9490b	6	17	of	of	ADP
fn106w9490b	6	18	tubules	tubule	NOUN
fn106w9490b	6	19	and	and	CCONJ
fn106w9490b	6	20	cysts	cyst	NOUN
fn106w9490b	6	21	,	,	PUNCT
fn106w9490b	6	22	the	the	DET
fn106w9490b	6	23	building	building	NOUN
fn106w9490b	6	24	blocks	block	NOUN
fn106w9490b	6	25	of	of	ADP
fn106w9490b	6	26	epithelial	epithelial	ADJ
fn106w9490b	6	27	glands	gland	NOUN
fn106w9490b	6	28	has	have	AUX
fn106w9490b	6	29	also	also	ADV
fn106w9490b	6	30	been	be	AUX
fn106w9490b	6	31	investigated	investigate	VERB
fn106w9490b	6	32	.	.	PUNCT
fn106w9490b	7	1	tubules	tubule	NOUN
fn106w9490b	7	2	form	form	VERB
fn106w9490b	7	3	in	in	ADP
fn106w9490b	7	4	response	response	NOUN
fn106w9490b	7	5	to	to	ADP
fn106w9490b	7	6	cues	cue	NOUN
fn106w9490b	7	7	derived	derive	VERB
fn106w9490b	7	8	from	from	ADP
fn106w9490b	7	9	morphogens	morphogen	NOUN
fn106w9490b	7	10	such	such	ADJ
fn106w9490b	7	11	as	as	ADP
fn106w9490b	7	12	hepatocyte	hepatocyte	NOUN
fn106w9490b	7	13	growth	growth	NOUN
fn106w9490b	7	14	factor	factor	NOUN
fn106w9490b	7	15	.	.	PUNCT
fn106w9490b	8	1	arf6	arf6	PROPN
fn106w9490b	8	2	is	be	AUX
fn106w9490b	8	3	transiently	transiently	ADV
fn106w9490b	8	4	activated	activate	VERB
fn106w9490b	8	5	during	during	ADP
fn106w9490b	8	6	tubulogenesis	tubulogenesis	NOUN
fn106w9490b	8	7	and	and	CCONJ
fn106w9490b	8	8	perturbing	perturb	VERB
fn106w9490b	8	9	the	the	DET
fn106w9490b	8	10	arf6	arf6	PROPN
fn106w9490b	8	11	gtp	gtp	PROPN
fn106w9490b	8	12	/	/	PROPN
fn106w9490b	8	13	gdp	gdp	PROPN
fn106w9490b	8	14	cycle	cycle	NOUN
fn106w9490b	8	15	by	by	ADP
fn106w9490b	8	16	inducible	inducible	ADJ
fn106w9490b	8	17	expression	expression	NOUN
fn106w9490b	8	18	of	of	ADP
fn106w9490b	8	19	arf6	arf6	PROPN
fn106w9490b	8	20	mutants	mutant	VERB
fn106w9490b	8	21	defective	defective	ADJ
fn106w9490b	8	22	in	in	ADP
fn106w9490b	8	23	gtp	gtp	PROPN
fn106w9490b	8	24	binding	binding	PROPN
fn106w9490b	8	25	or	or	CCONJ
fn106w9490b	8	26	hydrolysis	hydrolysis	NOUN
fn106w9490b	8	27	inhibits	inhibit	VERB
fn106w9490b	8	28	the	the	DET
fn106w9490b	8	29	development	development	NOUN
fn106w9490b	8	30	of	of	ADP
fn106w9490b	8	31	mature	mature	ADJ
fn106w9490b	8	32	tubules	tubule	NOUN
fn106w9490b	8	33	.	.	PUNCT
fn106w9490b	9	1	further	far	ADV
fn106w9490b	9	2	,	,	PUNCT
fn106w9490b	9	3	we	we	PRON
fn106w9490b	9	4	show	show	VERB
fn106w9490b	9	5	that	that	SCONJ
fn106w9490b	9	6	activation	activation	NOUN
fn106w9490b	9	7	of	of	ADP
fn106w9490b	9	8	arf6	arf6	PROPN
fn106w9490b	9	9	is	be	AUX
fn106w9490b	9	10	necessary	necessary	ADJ
fn106w9490b	9	11	and	and	CCONJ
fn106w9490b	9	12	sufficient	sufficient	ADJ
fn106w9490b	9	13	to	to	PART
fn106w9490b	9	14	initiate	initiate	VERB
fn106w9490b	9	15	tubule	tubule	NOUN
fn106w9490b	9	16	extension	extension	NOUN
fn106w9490b	9	17	.	.	PUNCT
fn106w9490b	10	1	arf6	arf6	PROPN
fn106w9490b	10	2	regulates	regulate	VERB
fn106w9490b	10	3	the	the	DET
fn106w9490b	10	4	subcellular	subcellular	ADJ
fn106w9490b	10	5	distribution	distribution	NOUN
fn106w9490b	10	6	of	of	ADP
fn106w9490b	10	7	the	the	DET
fn106w9490b	10	8	gtpase	gtpase	NOUN
fn106w9490b	10	9	,	,	PUNCT
fn106w9490b	10	10	rac1	rac1	PROPN
fn106w9490b	10	11	,	,	PUNCT
fn106w9490b	10	12	to	to	PART
fn106w9490b	10	13	tubule	tubule	NOUN
fn106w9490b	10	14	extensions	extension	NOUN
fn106w9490b	10	15	.	.	PUNCT
fn106w9490b	11	1	furthermore	furthermore	ADV
fn106w9490b	11	2	,	,	PUNCT
fn106w9490b	11	3	arf6	arf6	PROPN
fn106w9490b	11	4	-	-	PUNCT
fn106w9490b	11	5	induced	induce	VERB
fn106w9490b	11	6	erk	erk	NOUN
fn106w9490b	11	7	activation	activation	NOUN
fn106w9490b	11	8	regulates	regulate	VERB
fn106w9490b	11	9	rac1	rac1	PROPN
fn106w9490b	11	10	activation	activation	NOUN
fn106w9490b	11	11	during	during	ADP
fn106w9490b	11	12	tubule	tubule	NOUN
fn106w9490b	11	13	initiation	initiation	NOUN
fn106w9490b	11	14	through	through	ADP
fn106w9490b	11	15	the	the	DET
fn106w9490b	11	16	expression	expression	NOUN
fn106w9490b	11	17	of	of	ADP
fn106w9490b	11	18	the	the	DET
fn106w9490b	11	19	receptor	receptor	NOUN
fn106w9490b	11	20	for	for	ADP
fn106w9490b	11	21	urokinase	urokinase	NOUN
fn106w9490b	11	22	plasminogen	plasminogen	NOUN
fn106w9490b	11	23	activator	activator	NOUN
fn106w9490b	11	24	.	.	PUNCT
fn106w9490b	12	1	sustained	sustained	ADJ
fn106w9490b	12	2	activation	activation	NOUN
fn106w9490b	12	3	of	of	ADP
fn106w9490b	12	4	arf6	arf6	PROPN
fn106w9490b	12	5	also	also	ADV
fn106w9490b	12	6	inhibits	inhibit	VERB
fn106w9490b	12	7	the	the	DET
fn106w9490b	12	8	normal	normal	ADJ
fn106w9490b	12	9	progression	progression	NOUN
fn106w9490b	12	10	of	of	ADP
fn106w9490b	12	11	cyst	cyst	NOUN
fn106w9490b	12	12	development	development	NOUN
fn106w9490b	12	13	.	.	PUNCT
fn106w9490b	13	1	cysts	cyst	NOUN
fn106w9490b	13	2	expressing	express	VERB
fn106w9490b	13	3	an	an	DET
fn106w9490b	13	4	arf6	arf6	PROPN
fn106w9490b	13	5	-	-	PUNCT
fn106w9490b	13	6	gtp	gtp	PROPN
fn106w9490b	13	7	mutant	mutant	NOUN
fn106w9490b	13	8	exhibit	exhibit	VERB
fn106w9490b	13	9	a	a	DET
fn106w9490b	13	10	significant	significant	ADJ
fn106w9490b	13	11	pool	pool	NOUN
fn106w9490b	13	12	of	of	ADP
fn106w9490b	13	13	internalized	internalized	ADJ
fn106w9490b	13	14	e	e	NOUN
fn106w9490b	13	15	-	-	NOUN
fn106w9490b	13	16	cadherin	cadherin	NOUN
fn106w9490b	13	17	thereby	thereby	ADV
fn106w9490b	13	18	disrupting	disrupt	VERB
fn106w9490b	13	19	cyst	cyst	NOUN
fn106w9490b	13	20	architecture	architecture	NOUN
fn106w9490b	13	21	.	.	PUNCT
fn106w9490b	14	1	in	in	ADP
fn106w9490b	14	2	addition	addition	NOUN
fn106w9490b	14	3	,	,	PUNCT
fn106w9490b	14	4	the	the	DET
fn106w9490b	14	5	levels	level	NOUN
fn106w9490b	14	6	of	of	ADP
fn106w9490b	14	7	bcl-2	bcl-2	NOUN
fn106w9490b	14	8	are	be	AUX
fn106w9490b	14	9	higher	high	ADJ
fn106w9490b	14	10	in	in	ADP
fn106w9490b	14	11	arf6	arf6	PROPN
fn106w9490b	14	12	-	-	PUNCT
fn106w9490b	14	13	gtp	gtp	PROPN
fn106w9490b	14	14	cysts	cyst	NOUN
fn106w9490b	14	15	relative	relative	ADJ
fn106w9490b	14	16	to	to	ADP
fn106w9490b	14	17	normal	normal	ADJ
fn106w9490b	14	18	cysts	cyst	NOUN
fn106w9490b	14	19	thereby	thereby	ADV
fn106w9490b	14	20	affecting	affect	VERB
fn106w9490b	14	21	lumen	luman	NOUN
fn106w9490b	14	22	clearance	clearance	NOUN
fn106w9490b	14	23	by	by	ADP
fn106w9490b	14	24	apoptosis	apoptosis	NOUN
fn106w9490b	14	25	.	.	PUNCT
fn106w9490b	15	1	this	this	DET
fn106w9490b	15	2	latter	latter	ADJ
fn106w9490b	15	3	step	step	NOUN
fn106w9490b	15	4	is	be	AUX
fn106w9490b	15	5	dependent	dependent	ADJ
fn106w9490b	15	6	on	on	ADP
fn106w9490b	15	7	arf6	arf6	PROPN
fn106w9490b	15	8	regulated	regulate	VERB
fn106w9490b	15	9	erk	erk	PROPN
fn106w9490b	15	10	activation	activation	NOUN
fn106w9490b	15	11	,	,	PUNCT
fn106w9490b	15	12	which	which	PRON
fn106w9490b	15	13	in	in	ADP
fn106w9490b	15	14	turn	turn	NOUN
fn106w9490b	15	15	is	be	AUX
fn106w9490b	15	16	dependent	dependent	ADJ
fn106w9490b	15	17	on	on	ADP
fn106w9490b	15	18	pld	pld	PROPN
fn106w9490b	15	19	.	.	PUNCT
fn106w9490b	16	1	arf6	arf6	PROPN
fn106w9490b	16	2	-	-	PUNCT
fn106w9490b	16	3	dependent	dependent	ADJ
fn106w9490b	16	4	pld	pld	ADJ
fn106w9490b	16	5	activation	activation	NOUN
fn106w9490b	16	6	promotes	promote	VERB
fn106w9490b	16	7	receptor	receptor	NOUN
fn106w9490b	16	8	endocytosis	endocytosis	NOUN
fn106w9490b	16	9	that	that	PRON
fn106w9490b	16	10	ultimately	ultimately	ADV
fn106w9490b	16	11	permits	permit	VERB
fn106w9490b	16	12	erk	erk	NOUN
fn106w9490b	16	13	signaling	signal	VERB
fn106w9490b	16	14	from	from	ADP
fn106w9490b	16	15	intracellular	intracellular	ADJ
fn106w9490b	16	16	endosomes	endosome	NOUN
fn106w9490b	16	17	.	.	PUNCT
fn106w9490b	17	1	thus	thus	ADV
fn106w9490b	17	2	,	,	PUNCT
fn106w9490b	17	3	the	the	DET
fn106w9490b	17	4	studies	study	NOUN
fn106w9490b	17	5	described	describe	VERB
fn106w9490b	17	6	in	in	ADP
fn106w9490b	17	7	this	this	DET
fn106w9490b	17	8	research	research	NOUN
fn106w9490b	17	9	dissertation	dissertation	NOUN
fn106w9490b	17	10	have	have	AUX
fn106w9490b	17	11	identified	identify	VERB
fn106w9490b	17	12	a	a	DET
fn106w9490b	17	13	signaling	signal	VERB
fn106w9490b	17	14	apparatus	apparatus	NOUN
fn106w9490b	17	15	downstream	downstream	ADV
fn106w9490b	17	16	of	of	ADP
fn106w9490b	17	17	arf6	arf6	PROPN
fn106w9490b	17	18	activation	activation	NOUN
fn106w9490b	17	19	that	that	PRON
fn106w9490b	17	20	regulates	regulate	VERB
fn106w9490b	17	21	epithelial	epithelial	ADJ
fn106w9490b	17	22	morphogenesis	morphogenesis	NOUN
fn106w9490b	17	23	and	and	CCONJ
fn106w9490b	17	24	could	could	AUX
fn106w9490b	17	25	potentially	potentially	ADV
fn106w9490b	17	26	contribute	contribute	VERB
fn106w9490b	17	27	to	to	ADP
fn106w9490b	17	28	epithelial	epithelial	ADJ
fn106w9490b	17	29	cancer	cancer	NOUN
fn106w9490b	17	30	initiation	initiation	NOUN
fn106w9490b	17	31	and	and	CCONJ
fn106w9490b	17	32	progression	progression	NOUN
fn106w9490b	17	33	.	.	PUNCT