id	sid	tid	token	lemma	pos
fb494745k58	1	1	nearly	nearly	ADV
fb494745k58	1	2	500,000	500,000	NUM
fb494745k58	1	3	joint	joint	ADJ
fb494745k58	1	4	replacement	replacement	NOUN
fb494745k58	1	5	procedures	procedure	NOUN
fb494745k58	1	6	are	be	AUX
fb494745k58	1	7	performed	perform	VERB
fb494745k58	1	8	annually	annually	ADV
fb494745k58	1	9	with	with	ADP
fb494745k58	1	10	the	the	DET
fb494745k58	1	11	intention	intention	NOUN
fb494745k58	1	12	to	to	PART
fb494745k58	1	13	remove	remove	VERB
fb494745k58	1	14	damaged	damage	VERB
fb494745k58	1	15	tissue	tissue	NOUN
fb494745k58	1	16	and	and	CCONJ
fb494745k58	1	17	restore	restore	VERB
fb494745k58	1	18	normal	normal	ADJ
fb494745k58	1	19	joint	joint	ADJ
fb494745k58	1	20	activity	activity	NOUN
fb494745k58	1	21	to	to	ADP
fb494745k58	1	22	patients	patient	NOUN
fb494745k58	1	23	suffering	suffer	VERB
fb494745k58	1	24	from	from	ADP
fb494745k58	1	25	osteoarthritis	osteoarthritis	NOUN
fb494745k58	1	26	.	.	PUNCT
fb494745k58	2	1	current	current	ADJ
fb494745k58	2	2	methods	method	NOUN
fb494745k58	2	3	of	of	ADP
fb494745k58	2	4	joint	joint	ADJ
fb494745k58	2	5	fixation	fixation	NOUN
fb494745k58	2	6	are	be	AUX
fb494745k58	2	7	limited	limit	VERB
fb494745k58	2	8	to	to	ADP
fb494745k58	2	9	two	two	NUM
fb494745k58	2	10	methods	method	NOUN
fb494745k58	2	11	:	:	PUNCT
fb494745k58	2	12	the	the	DET
fb494745k58	2	13	use	use	NOUN
fb494745k58	2	14	of	of	ADP
fb494745k58	2	15	bone	bone	NOUN
fb494745k58	2	16	cement	cement	NOUN
fb494745k58	2	17	to	to	PART
fb494745k58	2	18	stabilize	stabilize	VERB
fb494745k58	2	19	the	the	DET
fb494745k58	2	20	orthopaedic	orthopaedic	ADJ
fb494745k58	2	21	implant	implant	NOUN
fb494745k58	2	22	in	in	ADP
fb494745k58	2	23	the	the	DET
fb494745k58	2	24	bone	bone	NOUN
fb494745k58	2	25	and	and	CCONJ
fb494745k58	2	26	the	the	DET
fb494745k58	2	27	use	use	NOUN
fb494745k58	2	28	of	of	ADP
fb494745k58	2	29	osseointegration	osseointegration	NOUN
fb494745k58	2	30	to	to	PART
fb494745k58	2	31	encourage	encourage	VERB
fb494745k58	2	32	bone	bone	NOUN
fb494745k58	2	33	to	to	PART
fb494745k58	2	34	integrate	integrate	VERB
fb494745k58	2	35	into	into	ADP
fb494745k58	2	36	the	the	DET
fb494745k58	2	37	implant	implant	ADJ
fb494745k58	2	38	surface	surface	NOUN
fb494745k58	2	39	.	.	PUNCT
fb494745k58	3	1	osseointegrative	osseointegrative	ADJ
fb494745k58	3	2	surfaces	surface	NOUN
fb494745k58	3	3	have	have	VERB
fb494745k58	3	4	lower	low	ADJ
fb494745k58	3	5	rates	rate	NOUN
fb494745k58	3	6	of	of	ADP
fb494745k58	3	7	revision	revision	NOUN
fb494745k58	3	8	surgery	surgery	NOUN
fb494745k58	3	9	,	,	PUNCT
fb494745k58	3	10	making	make	VERB
fb494745k58	3	11	it	it	PRON
fb494745k58	3	12	an	an	DET
fb494745k58	3	13	ideal	ideal	ADJ
fb494745k58	3	14	fixation	fixation	NOUN
fb494745k58	3	15	method	method	NOUN
fb494745k58	3	16	for	for	ADP
fb494745k58	3	17	younger	young	ADJ
fb494745k58	3	18	patients	patient	NOUN
fb494745k58	3	19	.	.	PUNCT
fb494745k58	4	1	however	however	ADV
fb494745k58	4	2	,	,	PUNCT
fb494745k58	4	3	current	current	ADJ
fb494745k58	4	4	osseointegrative	osseointegrative	ADJ
fb494745k58	4	5	technologies	technology	NOUN
fb494745k58	4	6	have	have	VERB
fb494745k58	4	7	yet	yet	ADV
fb494745k58	4	8	to	to	PART
fb494745k58	4	9	replace	replace	VERB
fb494745k58	4	10	bone	bone	NOUN
fb494745k58	4	11	cement	cement	NOUN
fb494745k58	4	12	as	as	ADP
fb494745k58	4	13	a	a	DET
fb494745k58	4	14	fixation	fixation	NOUN
fb494745k58	4	15	method	method	NOUN
fb494745k58	4	16	in	in	ADP
fb494745k58	4	17	total	total	ADJ
fb494745k58	4	18	knee	knee	NOUN
fb494745k58	4	19	arthroplasty	arthroplasty	NOUN
fb494745k58	4	20	,	,	PUNCT
fb494745k58	4	21	highlighting	highlight	VERB
fb494745k58	4	22	the	the	DET
fb494745k58	4	23	need	need	NOUN
fb494745k58	4	24	for	for	ADP
fb494745k58	4	25	improved	improved	ADJ
fb494745k58	4	26	surface	surface	NOUN
fb494745k58	4	27	designs	design	NOUN
fb494745k58	4	28	to	to	PART
fb494745k58	4	29	compensate	compensate	VERB
fb494745k58	4	30	for	for	ADP
fb494745k58	4	31	the	the	DET
fb494745k58	4	32	unique	unique	ADJ
fb494745k58	4	33	mechanics	mechanic	NOUN
fb494745k58	4	34	in	in	ADP
fb494745k58	4	35	the	the	DET
fb494745k58	4	36	knee	knee	NOUN
fb494745k58	4	37	.	.	PUNCT
fb494745k58	5	1	additive	additive	ADJ
fb494745k58	5	2	manufacturing	manufacturing	NOUN
fb494745k58	5	3	is	be	AUX
fb494745k58	5	4	a	a	DET
fb494745k58	5	5	highly	highly	ADV
fb494745k58	5	6	tunable	tunable	ADJ
fb494745k58	5	7	method	method	NOUN
fb494745k58	5	8	of	of	ADP
fb494745k58	5	9	design	design	NOUN
fb494745k58	5	10	that	that	PRON
fb494745k58	5	11	can	can	AUX
fb494745k58	5	12	be	be	AUX
fb494745k58	5	13	applied	apply	VERB
fb494745k58	5	14	to	to	ADP
fb494745k58	5	15	orthopaedic	orthopaedic	ADJ
fb494745k58	5	16	implants	implant	NOUN
fb494745k58	5	17	.	.	PUNCT
fb494745k58	6	1	however	however	ADV
fb494745k58	6	2	the	the	DET
fb494745k58	6	3	current	current	ADJ
fb494745k58	6	4	timeline	timeline	NOUN
fb494745k58	6	5	for	for	ADP
fb494745k58	6	6	exploring	explore	VERB
fb494745k58	6	7	new	new	ADJ
fb494745k58	6	8	scaffolds	scaffold	NOUN
fb494745k58	6	9	is	be	AUX
fb494745k58	6	10	resource	resource	NOUN
fb494745k58	6	11	intensive	intensive	ADJ
fb494745k58	6	12	and	and	CCONJ
fb494745k58	6	13	alternative	alternative	ADJ
fb494745k58	6	14	methods	method	NOUN
fb494745k58	6	15	of	of	ADP
fb494745k58	6	16	evaluating	evaluate	VERB
fb494745k58	6	17	design	design	NOUN
fb494745k58	6	18	iterations	iteration	NOUN
fb494745k58	6	19	needs	need	VERB
fb494745k58	6	20	to	to	PART
fb494745k58	6	21	be	be	AUX
fb494745k58	6	22	addressed.here	addressed.here	ADV
fb494745k58	6	23	an	an	PRON
fb494745k58	6	24	in	in	ADP
fb494745k58	6	25	situ	situ	ADJ
fb494745k58	6	26	bioreactor	bioreactor	NOUN
fb494745k58	6	27	was	be	AUX
fb494745k58	6	28	used	use	VERB
fb494745k58	6	29	for	for	ADP
fb494745k58	6	30	modeling	model	VERB
fb494745k58	6	31	bone	bone	NOUN
fb494745k58	6	32	formation	formation	NOUN
fb494745k58	6	33	into	into	ADP
fb494745k58	6	34	porous	porous	ADJ
fb494745k58	6	35	,	,	PUNCT
fb494745k58	6	36	additively	additively	ADV
fb494745k58	6	37	manufactured	manufacture	VERB
fb494745k58	6	38	scaffolds	scaffold	NOUN
fb494745k58	6	39	.	.	PUNCT
fb494745k58	7	1	scaffolds	scaffold	NOUN
fb494745k58	7	2	were	be	AUX
fb494745k58	7	3	inserted	insert	VERB
fb494745k58	7	4	into	into	ADP
fb494745k58	7	5	cancellous	cancellous	ADJ
fb494745k58	7	6	bone	bone	NOUN
fb494745k58	7	7	both	both	CCONJ
fb494745k58	7	8	normal	normal	ADJ
fb494745k58	7	9	and	and	CCONJ
fb494745k58	7	10	orthogonal	orthogonal	ADJ
fb494745k58	7	11	to	to	ADP
fb494745k58	7	12	loading	load	VERB
fb494745k58	7	13	to	to	PART
fb494745k58	7	14	provide	provide	VERB
fb494745k58	7	15	different	different	ADJ
fb494745k58	7	16	levels	level	NOUN
fb494745k58	7	17	of	of	ADP
fb494745k58	7	18	contact	contact	NOUN
fb494745k58	7	19	between	between	ADP
fb494745k58	7	20	the	the	DET
fb494745k58	7	21	two	two	NUM
fb494745k58	7	22	surfaces	surface	NOUN
fb494745k58	7	23	.	.	PUNCT
fb494745k58	8	1	initially	initially	ADV
fb494745k58	8	2	,	,	PUNCT
fb494745k58	8	3	an	an	DET
fb494745k58	8	4	in	in	ADP
fb494745k58	8	5	situ	situ	ADJ
fb494745k58	8	6	bioreactor	bioreactor	NOUN
fb494745k58	8	7	model	model	NOUN
fb494745k58	8	8	previously	previously	ADV
fb494745k58	8	9	used	use	VERB
fb494745k58	8	10	in	in	ADP
fb494745k58	8	11	bone	bone	NOUN
fb494745k58	8	12	marrow	marrow	NOUN
fb494745k58	8	13	mechanobiology	mechanobiology	NOUN
fb494745k58	8	14	studies	study	NOUN
fb494745k58	8	15	was	be	AUX
fb494745k58	8	16	used	use	VERB
fb494745k58	8	17	for	for	ADP
fb494745k58	8	18	evaluating	evaluate	VERB
fb494745k58	8	19	the	the	DET
fb494745k58	8	20	impact	impact	NOUN
fb494745k58	8	21	of	of	ADP
fb494745k58	8	22	a	a	DET
fb494745k58	8	23	wnt	wnt	PROPN
fb494745k58	8	24	agonist	agonist	NOUN
fb494745k58	8	25	and	and	CCONJ
fb494745k58	8	26	its	its	PRON
fb494745k58	8	27	impact	impact	NOUN
fb494745k58	8	28	on	on	ADP
fb494745k58	8	29	bone	bone	NOUN
fb494745k58	8	30	formation	formation	NOUN
fb494745k58	8	31	.	.	PUNCT
fb494745k58	9	1	additionally	additionally	ADV
fb494745k58	9	2	circulating	circulate	VERB
fb494745k58	9	3	chemokines	chemokine	NOUN
fb494745k58	9	4	within	within	ADP
fb494745k58	9	5	the	the	DET
fb494745k58	9	6	media	medium	NOUN
fb494745k58	9	7	and	and	CCONJ
fb494745k58	9	8	the	the	DET
fb494745k58	9	9	importance	importance	NOUN
fb494745k58	9	10	of	of	ADP
fb494745k58	9	11	maintaining	maintain	VERB
fb494745k58	9	12	them	they	PRON
fb494745k58	9	13	within	within	ADP
fb494745k58	9	14	the	the	DET
fb494745k58	9	15	media	medium	NOUN
fb494745k58	9	16	was	be	AUX
fb494745k58	9	17	shown	show	VERB
fb494745k58	9	18	to	to	PART
fb494745k58	9	19	retain	retain	VERB
fb494745k58	9	20	normal	normal	ADJ
fb494745k58	9	21	bone	bone	NOUN
fb494745k58	9	22	remodeling	remodeling	NOUN
fb494745k58	9	23	behavior	behavior	NOUN
fb494745k58	9	24	.	.	PUNCT
fb494745k58	10	1	osseointegration	osseointegration	NOUN
fb494745k58	10	2	due	due	ADP
fb494745k58	10	3	to	to	ADP
fb494745k58	10	4	mechanical	mechanical	ADJ
fb494745k58	10	5	stimulation	stimulation	NOUN
fb494745k58	10	6	of	of	ADP
fb494745k58	10	7	bone	bone	NOUN
fb494745k58	10	8	marrow	marrow	NOUN
fb494745k58	10	9	alone	alone	ADV
fb494745k58	10	10	was	be	AUX
fb494745k58	10	11	also	also	ADV
fb494745k58	10	12	explored	explore	VERB
fb494745k58	10	13	.	.	PUNCT
fb494745k58	11	1	stimulation	stimulation	NOUN
fb494745k58	11	2	of	of	ADP
fb494745k58	11	3	bone	bone	NOUN
fb494745k58	11	4	marrow	marrow	NOUN
fb494745k58	11	5	resulted	result	VERB
fb494745k58	11	6	in	in	ADP
fb494745k58	11	7	bone	bone	NOUN
fb494745k58	11	8	formation	formation	NOUN
fb494745k58	11	9	within	within	ADP
fb494745k58	11	10	scaffold	scaffold	NOUN
fb494745k58	11	11	pores	pore	NOUN
fb494745k58	11	12	.	.	PUNCT
fb494745k58	12	1	when	when	SCONJ
fb494745k58	12	2	the	the	DET
fb494745k58	12	3	same	same	ADJ
fb494745k58	12	4	orientation	orientation	NOUN
fb494745k58	12	5	was	be	AUX
fb494745k58	12	6	subjected	subject	VERB
fb494745k58	12	7	to	to	ADP
fb494745k58	12	8	compressive	compressive	ADJ
fb494745k58	12	9	loading	loading	NOUN
fb494745k58	12	10	,	,	PUNCT
fb494745k58	12	11	bone	bone	NOUN
fb494745k58	12	12	formation	formation	NOUN
fb494745k58	12	13	did	do	AUX
fb494745k58	12	14	not	not	PART
fb494745k58	12	15	increase	increase	VERB
fb494745k58	12	16	,	,	PUNCT
fb494745k58	12	17	supporting	support	VERB
fb494745k58	12	18	the	the	DET
fb494745k58	12	19	need	need	NOUN
fb494745k58	12	20	for	for	ADP
fb494745k58	12	21	increased	increase	VERB
fb494745k58	12	22	mechanical	mechanical	ADJ
fb494745k58	12	23	strain	strain	NOUN
fb494745k58	12	24	in	in	ADP
fb494745k58	12	25	the	the	DET
fb494745k58	12	26	bone	bone	NOUN
fb494745k58	12	27	.	.	PUNCT
fb494745k58	13	1	finally	finally	ADV
fb494745k58	13	2	,	,	PUNCT
fb494745k58	13	3	a	a	DET
fb494745k58	13	4	transverse	transverse	NOUN
fb494745k58	13	5	loading	loading	NOUN
fb494745k58	13	6	model	model	NOUN
fb494745k58	13	7	was	be	AUX
fb494745k58	13	8	designed	design	VERB
fb494745k58	13	9	.	.	PUNCT
fb494745k58	14	1	three	three	NUM
fb494745k58	14	2	different	different	ADJ
fb494745k58	14	3	magnitudes	magnitude	NOUN
fb494745k58	14	4	of	of	ADP
fb494745k58	14	5	compressive	compressive	ADJ
fb494745k58	14	6	loading	loading	NOUN
fb494745k58	14	7	were	be	AUX
fb494745k58	14	8	applied	apply	VERB
fb494745k58	14	9	to	to	ADP
fb494745k58	14	10	bones	bone	NOUN
fb494745k58	14	11	with	with	ADP
fb494745k58	14	12	scaffolds	scaffold	NOUN
fb494745k58	14	13	inserted	insert	VERB
fb494745k58	14	14	orthogonal	orthogonal	ADJ
fb494745k58	14	15	to	to	ADP
fb494745k58	14	16	loading	loading	NOUN
fb494745k58	14	17	.	.	PUNCT
fb494745k58	15	1	strains	strain	NOUN
fb494745k58	15	2	in	in	ADP
fb494745k58	15	3	the	the	DET
fb494745k58	15	4	bone	bone	NOUN
fb494745k58	15	5	were	be	AUX
fb494745k58	15	6	higher	high	ADJ
fb494745k58	15	7	and	and	CCONJ
fb494745k58	15	8	fell	fall	VERB
fb494745k58	15	9	within	within	ADP
fb494745k58	15	10	the	the	DET
fb494745k58	15	11	normal	normal	ADJ
fb494745k58	15	12	physiological	physiological	ADJ
fb494745k58	15	13	range	range	NOUN
fb494745k58	15	14	and	and	CCONJ
fb494745k58	15	15	resulted	result	VERB
fb494745k58	15	16	in	in	ADP
fb494745k58	15	17	the	the	DET
fb494745k58	15	18	highest	high	ADJ
fb494745k58	15	19	areas	area	NOUN
fb494745k58	15	20	of	of	ADP
fb494745k58	15	21	bone	bone	NOUN
fb494745k58	15	22	measured	measure	VERB
fb494745k58	15	23	.	.	PUNCT
fb494745k58	16	1	interestingly	interestingly	ADV
fb494745k58	16	2	,	,	PUNCT
fb494745k58	16	3	location	location	NOUN
fb494745k58	16	4	along	along	ADP
fb494745k58	16	5	the	the	DET
fb494745k58	16	6	scaffold	scaffold	NOUN
fb494745k58	16	7	surface	surface	NOUN
fb494745k58	16	8	did	do	AUX
fb494745k58	16	9	not	not	PART
fb494745k58	16	10	impact	impact	VERB
fb494745k58	16	11	overall	overall	ADJ
fb494745k58	16	12	bone	bone	NOUN
fb494745k58	16	13	ingrowth	ingrowth	NOUN
fb494745k58	16	14	into	into	ADP
fb494745k58	16	15	the	the	DET
fb494745k58	16	16	pores	pore	NOUN
fb494745k58	16	17	.	.	PUNCT
fb494745k58	17	1	while	while	SCONJ
fb494745k58	17	2	overall	overall	ADJ
fb494745k58	17	3	ingrowth	ingrowth	NOUN
fb494745k58	17	4	was	be	AUX
fb494745k58	17	5	less	less	ADJ
fb494745k58	17	6	than	than	ADP
fb494745k58	17	7	values	value	NOUN
fb494745k58	17	8	measured	measure	VERB
fb494745k58	17	9	in	in	ADP
fb494745k58	17	10	vivo	vivo	PROPN
fb494745k58	17	11	,	,	PUNCT
fb494745k58	17	12	depth	depth	NOUN
fb494745k58	17	13	penetration	penetration	NOUN
fb494745k58	17	14	aligns	align	VERB
fb494745k58	17	15	with	with	ADP
fb494745k58	17	16	current	current	ADJ
fb494745k58	17	17	in	in	ADP
fb494745k58	17	18	vivo	vivo	NOUN
fb494745k58	17	19	reports	report	NOUN
fb494745k58	17	20	.	.	PUNCT
fb494745k58	18	1	this	this	PRON
fb494745k58	18	2	is	be	AUX
fb494745k58	18	3	the	the	DET
fb494745k58	18	4	first	first	ADJ
fb494745k58	18	5	time	time	NOUN
fb494745k58	18	6	that	that	PRON
fb494745k58	18	7	bone	bone	NOUN
fb494745k58	18	8	formation	formation	NOUN
fb494745k58	18	9	has	have	AUX
fb494745k58	18	10	been	be	AUX
fb494745k58	18	11	modeled	model	VERB
fb494745k58	18	12	in	in	ADP
fb494745k58	18	13	situ	situ	NOUN
fb494745k58	18	14	and	and	CCONJ
fb494745k58	18	15	provides	provide	VERB
fb494745k58	18	16	a	a	DET
fb494745k58	18	17	unique	unique	ADJ
fb494745k58	18	18	evaluation	evaluation	NOUN
fb494745k58	18	19	method	method	NOUN
fb494745k58	18	20	of	of	ADP
fb494745k58	18	21	new	new	ADJ
fb494745k58	18	22	orthopaedic	orthopaedic	ADJ
fb494745k58	18	23	scaffold	scaffold	NOUN
fb494745k58	18	24	designs	design	NOUN
fb494745k58	18	25	.	.	PUNCT
fb494745k58	19	1	these	these	DET
fb494745k58	19	2	studies	study	NOUN
fb494745k58	19	3	highlight	highlight	VERB
fb494745k58	19	4	the	the	DET
fb494745k58	19	5	potential	potential	NOUN
fb494745k58	19	6	for	for	ADP
fb494745k58	19	7	an	an	PRON
fb494745k58	19	8	in	in	ADP
fb494745k58	19	9	situ	situ	ADJ
fb494745k58	19	10	method	method	NOUN
fb494745k58	19	11	for	for	ADP
fb494745k58	19	12	evaluating	evaluate	VERB
fb494745k58	19	13	everchanging	everchange	VERB
fb494745k58	19	14	scaffold	scaffold	NOUN
fb494745k58	19	15	designs	design	NOUN
fb494745k58	19	16	prior	prior	ADV
fb494745k58	19	17	to	to	ADP
fb494745k58	19	18	in	in	ADP
fb494745k58	19	19	vivo	vivo	ADJ
fb494745k58	19	20	testing	testing	NOUN
fb494745k58	19	21	.	.	PUNCT
fb494745k58	20	1	beyond	beyond	ADP
fb494745k58	20	2	preclinical	preclinical	ADJ
fb494745k58	20	3	testing	testing	NOUN
fb494745k58	20	4	,	,	PUNCT
fb494745k58	20	5	this	this	DET
fb494745k58	20	6	system	system	NOUN
fb494745k58	20	7	could	could	AUX
fb494745k58	20	8	further	further	VERB
fb494745k58	20	9	the	the	DET
fb494745k58	20	10	understanding	understanding	NOUN
fb494745k58	20	11	of	of	ADP
fb494745k58	20	12	osseointegration	osseointegration	NOUN
fb494745k58	20	13	at	at	ADP
fb494745k58	20	14	a	a	DET
fb494745k58	20	15	local	local	ADJ
fb494745k58	20	16	level	level	NOUN
fb494745k58	20	17	,	,	PUNCT
fb494745k58	20	18	resulting	result	VERB
fb494745k58	20	19	from	from	ADP
fb494745k58	20	20	both	both	DET
fb494745k58	20	21	mechanical	mechanical	ADJ
fb494745k58	20	22	and	and	CCONJ
fb494745k58	20	23	biochemical	biochemical	ADJ
fb494745k58	20	24	interactions	interaction	NOUN
fb494745k58	20	25	,	,	PUNCT
fb494745k58	20	26	ultimately	ultimately	ADV
fb494745k58	20	27	influencing	influence	VERB
fb494745k58	20	28	new	new	ADJ
fb494745k58	20	29	implant	implant	ADJ
fb494745k58	20	30	designs	design	NOUN
fb494745k58	20	31	.	.	PUNCT