id sid tid token lemma pos f7623b61v6z 1 1 two two NUM f7623b61v6z 1 2 - - PUNCT f7623b61v6z 1 3 component component NOUN f7623b61v6z 1 4 gene gene NOUN f7623b61v6z 1 5 regulatory regulatory ADJ f7623b61v6z 1 6 systems system NOUN f7623b61v6z 1 7 in in ADP f7623b61v6z 1 8 bacteria bacteria NOUN f7623b61v6z 1 9 play play VERB f7623b61v6z 1 10 important important ADJ f7623b61v6z 1 11 roles role NOUN f7623b61v6z 1 12 in in ADP f7623b61v6z 1 13 regulating regulate VERB f7623b61v6z 1 14 expression expression NOUN f7623b61v6z 1 15 of of ADP f7623b61v6z 1 16 genes gene NOUN f7623b61v6z 1 17 encoding encode VERB f7623b61v6z 1 18 bacterial bacterial ADJ f7623b61v6z 1 19 toxins toxin NOUN f7623b61v6z 1 20 , , PUNCT f7623b61v6z 1 21 along along ADP f7623b61v6z 1 22 with with ADP f7623b61v6z 1 23 other other ADJ f7623b61v6z 1 24 virulence virulence NOUN f7623b61v6z 1 25 factors factor NOUN f7623b61v6z 1 26 that that PRON f7623b61v6z 1 27 interact interact VERB f7623b61v6z 1 28 with with ADP f7623b61v6z 1 29 the the DET f7623b61v6z 1 30 host host NOUN f7623b61v6z 1 31 and and CCONJ f7623b61v6z 1 32 promote promote VERB f7623b61v6z 1 33 survival survival NOUN f7623b61v6z 1 34 of of ADP f7623b61v6z 1 35 bacteria bacteria NOUN f7623b61v6z 1 36 in in ADP f7623b61v6z 1 37 vivo vivo PROPN f7623b61v6z 1 38 . . PUNCT f7623b61v6z 2 1 in in ADP f7623b61v6z 2 2 group group PROPN f7623b61v6z 2 3 a a DET f7623b61v6z 2 4 streptococcus streptococcus NOUN f7623b61v6z 2 5 pyogenes pyogene NOUN f7623b61v6z 2 6 ( ( PUNCT f7623b61v6z 2 7 gas gas NOUN f7623b61v6z 2 8 ) ) PUNCT f7623b61v6z 2 9 , , PUNCT f7623b61v6z 2 10 ∼13 ∼13 NOUN f7623b61v6z 2 11 such such ADJ f7623b61v6z 2 12 regulators regulator NOUN f7623b61v6z 2 13 are be AUX f7623b61v6z 2 14 known know VERB f7623b61v6z 2 15 . . PUNCT f7623b61v6z 3 1 the the DET f7623b61v6z 3 2 most most ADV f7623b61v6z 3 3 well well ADV f7623b61v6z 3 4 studied study VERB f7623b61v6z 3 5 of of ADP f7623b61v6z 3 6 these these PRON f7623b61v6z 3 7 is be AUX f7623b61v6z 3 8 the the DET f7623b61v6z 3 9 control control NOUN f7623b61v6z 3 10 of of ADP f7623b61v6z 3 11 virulence virulence NOUN f7623b61v6z 3 12 ( ( PUNCT f7623b61v6z 3 13 cov cov PROPN f7623b61v6z 3 14 ) ) PUNCT f7623b61v6z 3 15 intracellular intracellular ADJ f7623b61v6z 3 16 responder responder NOUN f7623b61v6z 3 17 ( ( PUNCT f7623b61v6z 3 18 covr)/extracellular covr)/extracellular ADJ f7623b61v6z 3 19 sensor sensor NOUN f7623b61v6z 3 20 ( ( PUNCT f7623b61v6z 3 21 covs covs PROPN f7623b61v6z 3 22 ) ) PUNCT f7623b61v6z 3 23 system system NOUN f7623b61v6z 3 24 ( ( PUNCT f7623b61v6z 3 25 covrs covrs PROPN f7623b61v6z 3 26 ) ) PUNCT f7623b61v6z 3 27 , , PUNCT f7623b61v6z 3 28 in in ADP f7623b61v6z 3 29 which which PRON f7623b61v6z 3 30 environmental environmental ADJ f7623b61v6z 3 31 changes change NOUN f7623b61v6z 3 32 are be AUX f7623b61v6z 3 33 " " PUNCT f7623b61v6z 3 34 sensed sense VERB f7623b61v6z 3 35 " " PUNCT f7623b61v6z 3 36 by by ADP f7623b61v6z 3 37 the the DET f7623b61v6z 3 38 gene gene NOUN f7623b61v6z 3 39 product product NOUN f7623b61v6z 3 40 ( ( PUNCT f7623b61v6z 3 41 covs covs PROPN f7623b61v6z 3 42 ) ) PUNCT f7623b61v6z 3 43 of of ADP f7623b61v6z 3 44 covs covs PROPN f7623b61v6z 3 45 and and CCONJ f7623b61v6z 3 46 transmitted transmit VERB f7623b61v6z 3 47 to to ADP f7623b61v6z 3 48 its its PRON f7623b61v6z 3 49 cognate cognate ADJ f7623b61v6z 3 50 protein protein NOUN f7623b61v6z 3 51 product product NOUN f7623b61v6z 3 52 of of ADP f7623b61v6z 3 53 covr covr NOUN f7623b61v6z 3 54 ( ( PUNCT f7623b61v6z 3 55 covr covr NOUN f7623b61v6z 3 56 ) ) PUNCT f7623b61v6z 3 57 via via ADP f7623b61v6z 3 58 phosphorylation phosphorylation NOUN f7623b61v6z 3 59 - - PUNCT f7623b61v6z 3 60 dephosphorylation dephosphorylation NOUN f7623b61v6z 3 61 . . PUNCT f7623b61v6z 4 1 covrs covrs PROPN f7623b61v6z 4 2 regulates regulate VERB f7623b61v6z 4 3 a a DET f7623b61v6z 4 4 large large ADJ f7623b61v6z 4 5 number number NOUN f7623b61v6z 4 6 of of ADP f7623b61v6z 4 7 gas gas NOUN f7623b61v6z 4 8 virulence virulence NOUN f7623b61v6z 4 9 genes gene NOUN f7623b61v6z 4 10 involved involve VERB f7623b61v6z 4 11 in in ADP f7623b61v6z 4 12 invasiveness invasiveness NOUN f7623b61v6z 4 13 and and CCONJ f7623b61v6z 4 14 antiphagocytosis antiphagocytosis NOUN f7623b61v6z 4 15 , , PUNCT f7623b61v6z 4 16 e.g. e.g. X f7623b61v6z 4 17 , , PUNCT f7623b61v6z 4 18 cysteine cysteine NOUN f7623b61v6z 4 19 protease protease NOUN f7623b61v6z 4 20 ( ( PUNCT f7623b61v6z 4 21 speb speb PROPN f7623b61v6z 4 22 ) ) PUNCT f7623b61v6z 4 23 , , PUNCT f7623b61v6z 4 24 fibronectin fibronectin NOUN f7623b61v6z 4 25 binding bind VERB f7623b61v6z 4 26 protein protein NOUN f7623b61v6z 4 27 ( ( PUNCT f7623b61v6z 4 28 sfb1 sfb1 PROPN f7623b61v6z 4 29 ) ) PUNCT f7623b61v6z 4 30 , , PUNCT f7623b61v6z 4 31 hyaluronic hyaluronic ADJ f7623b61v6z 4 32 acid acid PROPN f7623b61v6z 4 33 capsule capsule PROPN f7623b61v6z 4 34 ( ( PUNCT f7623b61v6z 4 35 hasabc hasabc PROPN f7623b61v6z 4 36 ) ) PUNCT f7623b61v6z 4 37 , , PUNCT f7623b61v6z 4 38 and and CCONJ f7623b61v6z 4 39 streptokinase streptokinase PROPN f7623b61v6z 4 40 ( ( PUNCT f7623b61v6z 4 41 sk sk PROPN f7623b61v6z 4 42 ) ) PUNCT f7623b61v6z 4 43 . . PUNCT f7623b61v6z 5 1 deletion deletion NOUN f7623b61v6z 5 2 of of ADP f7623b61v6z 5 3 covrs covrs PROPN f7623b61v6z 5 4 derepressed derepresse VERB f7623b61v6z 5 5 the the DET f7623b61v6z 5 6 expression expression NOUN f7623b61v6z 5 7 of of ADP f7623b61v6z 5 8 these these DET f7623b61v6z 5 9 virulence virulence NOUN f7623b61v6z 5 10 factors factor NOUN f7623b61v6z 5 11 and and CCONJ f7623b61v6z 5 12 enhanced enhance VERB f7623b61v6z 5 13 the the DET f7623b61v6z 5 14 survival survival NOUN f7623b61v6z 5 15 of of ADP f7623b61v6z 5 16 gas gas NOUN f7623b61v6z 5 17 in in ADP f7623b61v6z 5 18 murine murine NOUN f7623b61v6z 5 19 infection infection NOUN f7623b61v6z 5 20 models model NOUN f7623b61v6z 5 21 . . PUNCT f7623b61v6z 6 1 however however ADV f7623b61v6z 6 2 , , PUNCT f7623b61v6z 6 3 specific specific ADJ f7623b61v6z 6 4 mechanisms mechanism NOUN f7623b61v6z 6 5 by by ADP f7623b61v6z 6 6 which which PRON f7623b61v6z 6 7 the the DET f7623b61v6z 6 8 covrs covrs ADJ f7623b61v6z 6 9 system system NOUN f7623b61v6z 6 10 regulates regulate VERB f7623b61v6z 6 11 the the DET f7623b61v6z 6 12 phagocytosis phagocytosis NOUN f7623b61v6z 6 13 of of ADP f7623b61v6z 6 14 gas gas NOUN f7623b61v6z 6 15 in in ADP f7623b61v6z 6 16 humans human NOUN f7623b61v6z 6 17 are be AUX f7623b61v6z 6 18 incomplete incomplete ADJ f7623b61v6z 6 19 . . PUNCT f7623b61v6z 7 1 the the DET f7623b61v6z 7 2 goal goal NOUN f7623b61v6z 7 3 of of ADP f7623b61v6z 7 4 this this DET f7623b61v6z 7 5 study study NOUN f7623b61v6z 7 6 is be AUX f7623b61v6z 7 7 centered center VERB f7623b61v6z 7 8 on on ADP f7623b61v6z 7 9 examining examine VERB f7623b61v6z 7 10 the the DET f7623b61v6z 7 11 role role NOUN f7623b61v6z 7 12 of of ADP f7623b61v6z 7 13 the the DET f7623b61v6z 7 14 covrs covrs ADJ f7623b61v6z 7 15 system system NOUN f7623b61v6z 7 16 in in ADP f7623b61v6z 7 17 regulating regulate VERB f7623b61v6z 7 18 complement complement NOUN f7623b61v6z 7 19 - - PUNCT f7623b61v6z 7 20 mediated mediate VERB f7623b61v6z 7 21 opsonophagocytosis opsonophagocytosis NOUN f7623b61v6z 7 22 of of ADP f7623b61v6z 7 23 gas gas NOUN f7623b61v6z 7 24 using use VERB f7623b61v6z 7 25 both both CCONJ f7623b61v6z 7 26 in in ADP f7623b61v6z 7 27 vitro vitro X f7623b61v6z 7 28 and and CCONJ f7623b61v6z 7 29 in in ADP f7623b61v6z 7 30 vivo vivo ADJ f7623b61v6z 7 31 systems.evasion systems.evasion NOUN f7623b61v6z 7 32 of of ADP f7623b61v6z 7 33 complement complement NOUN f7623b61v6z 7 34 - - PUNCT f7623b61v6z 7 35 mediated mediate VERB f7623b61v6z 7 36 opsonophagocytosis opsonophagocytosis NOUN f7623b61v6z 7 37 enables enable VERB f7623b61v6z 7 38 gas gas NOUN f7623b61v6z 7 39 to to PART f7623b61v6z 7 40 establish establish VERB f7623b61v6z 7 41 infection infection NOUN f7623b61v6z 7 42 . . PUNCT f7623b61v6z 8 1 in in ADP f7623b61v6z 8 2 general general ADJ f7623b61v6z 8 3 , , PUNCT f7623b61v6z 8 4 gas gas NOUN f7623b61v6z 8 5 inhibits inhibit VERB f7623b61v6z 8 6 the the DET f7623b61v6z 8 7 amplification amplification NOUN f7623b61v6z 8 8 of of ADP f7623b61v6z 8 9 the the DET f7623b61v6z 8 10 complement complement NOUN f7623b61v6z 8 11 cascade cascade NOUN f7623b61v6z 8 12 on on ADP f7623b61v6z 8 13 its its PRON f7623b61v6z 8 14 cell cell NOUN f7623b61v6z 8 15 surface surface NOUN f7623b61v6z 8 16 by by ADP f7623b61v6z 8 17 facilitating facilitate VERB f7623b61v6z 8 18 the the DET f7623b61v6z 8 19 degradation degradation NOUN f7623b61v6z 8 20 of of ADP f7623b61v6z 8 21 c3b c3b NOUN f7623b61v6z 8 22 , , PUNCT f7623b61v6z 8 23 an an DET f7623b61v6z 8 24 opsonin opsonin NOUN f7623b61v6z 8 25 , , PUNCT f7623b61v6z 8 26 to to ADP f7623b61v6z 8 27 an an DET f7623b61v6z 8 28 inactive inactive ADJ f7623b61v6z 8 29 product product NOUN f7623b61v6z 8 30 , , PUNCT f7623b61v6z 8 31 inactivated inactivate VERB f7623b61v6z 8 32 c3b c3b NOUN f7623b61v6z 8 33 ( ( PUNCT f7623b61v6z 8 34 ic3b ic3b PROPN f7623b61v6z 8 35 ) ) PUNCT f7623b61v6z 8 36 , , PUNCT f7623b61v6z 8 37 in in ADP f7623b61v6z 8 38 a a DET f7623b61v6z 8 39 step step NOUN f7623b61v6z 8 40 catalyzed catalyze VERB f7623b61v6z 8 41 by by ADP f7623b61v6z 8 42 factor factor NOUN f7623b61v6z 8 43 i i PRON f7623b61v6z 8 44 ( ( PUNCT f7623b61v6z 8 45 fi fi PROPN f7623b61v6z 8 46 ) ) PUNCT f7623b61v6z 8 47 and and CCONJ f7623b61v6z 8 48 its its PRON f7623b61v6z 8 49 cofactor cofactor NOUN f7623b61v6z 8 50 , , PUNCT f7623b61v6z 8 51 factor factor NOUN f7623b61v6z 8 52 h h PROPN f7623b61v6z 8 53 ( ( PUNCT f7623b61v6z 8 54 fh fh PROPN f7623b61v6z 8 55 ) ) PUNCT f7623b61v6z 8 56 , , PUNCT f7623b61v6z 8 57 with with ADP f7623b61v6z 8 58 or or CCONJ f7623b61v6z 8 59 without without ADP f7623b61v6z 8 60 the the DET f7623b61v6z 8 61 participation participation NOUN f7623b61v6z 8 62 of of ADP f7623b61v6z 8 63 human human ADJ f7623b61v6z 8 64 host host NOUN f7623b61v6z 8 65 plasmin plasmin NOUN f7623b61v6z 8 66 ( ( PUNCT f7623b61v6z 8 67 hpm hpm NOUN f7623b61v6z 8 68 ) ) PUNCT f7623b61v6z 8 69 . . PUNCT f7623b61v6z 9 1 using use VERB f7623b61v6z 9 2 gas gas NOUN f7623b61v6z 9 3 strain strain NOUN f7623b61v6z 9 4 ap53 ap53 PROPN f7623b61v6z 9 5 , , PUNCT f7623b61v6z 9 6 which which PRON f7623b61v6z 9 7 strongly strongly ADV f7623b61v6z 9 8 binds bind VERB f7623b61v6z 9 9 host host NOUN f7623b61v6z 9 10 human human ADJ f7623b61v6z 9 11 plasminogen plasminogen NOUN f7623b61v6z 9 12 / / SYM f7623b61v6z 9 13 plasmin plasmin PROPN f7623b61v6z 9 14 ( ( PUNCT f7623b61v6z 9 15 hpg hpg PROPN f7623b61v6z 9 16 / / SYM f7623b61v6z 9 17 hpm hpm NOUN f7623b61v6z 9 18 ) ) PUNCT f7623b61v6z 9 19 , , PUNCT f7623b61v6z 9 20 this this DET f7623b61v6z 9 21 study study NOUN f7623b61v6z 9 22 identified identify VERB f7623b61v6z 9 23 a a DET f7623b61v6z 9 24 key key ADJ f7623b61v6z 9 25 role role NOUN f7623b61v6z 9 26 for for ADP f7623b61v6z 9 27 covrs covrs PROPN f7623b61v6z 9 28 in in ADP f7623b61v6z 9 29 the the DET f7623b61v6z 9 30 regulation regulation NOUN f7623b61v6z 9 31 of of ADP f7623b61v6z 9 32 opsonophagocytosis opsonophagocytosis NOUN f7623b61v6z 9 33 of of ADP f7623b61v6z 9 34 gas gas NOUN f7623b61v6z 9 35 by by ADP f7623b61v6z 9 36 the the DET f7623b61v6z 9 37 host host NOUN f7623b61v6z 9 38 complement complement NOUN f7623b61v6z 9 39 system system NOUN f7623b61v6z 9 40 . . PUNCT f7623b61v6z 10 1 ap53 ap53 PROPN f7623b61v6z 10 2 cells cell NOUN f7623b61v6z 10 3 displayed display VERB f7623b61v6z 10 4 potent potent ADJ f7623b61v6z 10 5 binding binding NOUN f7623b61v6z 10 6 of of ADP f7623b61v6z 10 7 the the DET f7623b61v6z 10 8 host host NOUN f7623b61v6z 10 9 complement complement NOUN f7623b61v6z 10 10 inhibitor inhibitor NOUN f7623b61v6z 10 11 , , PUNCT f7623b61v6z 10 12 factor factor NOUN f7623b61v6z 10 13 h h PROPN f7623b61v6z 10 14 ( ( PUNCT f7623b61v6z 10 15 fh fh PROPN f7623b61v6z 10 16 ) ) PUNCT f7623b61v6z 10 17 , , PUNCT f7623b61v6z 10 18 which which PRON f7623b61v6z 10 19 concomitantly concomitantly ADV f7623b61v6z 10 20 led lead VERB f7623b61v6z 10 21 to to ADP f7623b61v6z 10 22 minimal minimal ADJ f7623b61v6z 10 23 c3b c3b NOUN f7623b61v6z 10 24 deposition deposition NOUN f7623b61v6z 10 25 on on ADP f7623b61v6z 10 26 ap53 ap53 PROPN f7623b61v6z 10 27 cells cell NOUN f7623b61v6z 10 28 . . PUNCT f7623b61v6z 11 1 this this PRON f7623b61v6z 11 2 resulted result VERB f7623b61v6z 11 3 in in ADP f7623b61v6z 11 4 weak weak ADJ f7623b61v6z 11 5 killing killing NOUN f7623b61v6z 11 6 of of ADP f7623b61v6z 11 7 the the DET f7623b61v6z 11 8 bacteria bacteria NOUN f7623b61v6z 11 9 by by ADP f7623b61v6z 11 10 human human ADJ f7623b61v6z 11 11 neutrophils neutrophil NOUN f7623b61v6z 11 12 and and CCONJ f7623b61v6z 11 13 a a DET f7623b61v6z 11 14 corresponding corresponding ADJ f7623b61v6z 11 15 high high ADJ f7623b61v6z 11 16 death death NOUN f7623b61v6z 11 17 rate rate NOUN f7623b61v6z 11 18 of of ADP f7623b61v6z 11 19 mice mouse NOUN f7623b61v6z 11 20 after after ADP f7623b61v6z 11 21 injection injection NOUN f7623b61v6z 11 22 of of ADP f7623b61v6z 11 23 these these DET f7623b61v6z 11 24 cells cell NOUN f7623b61v6z 11 25 . . PUNCT f7623b61v6z 12 1 ap53 ap53 PROPN f7623b61v6z 12 2 recruits recruit VERB f7623b61v6z 12 3 fh fh PROPN f7623b61v6z 12 4 to to ADP f7623b61v6z 12 5 its its PRON f7623b61v6z 12 6 cell cell NOUN f7623b61v6z 12 7 surface surface NOUN f7623b61v6z 12 8 via via ADP f7623b61v6z 12 9 a a DET f7623b61v6z 12 10 fh fh PROPN f7623b61v6z 12 11 receptor receptor NOUN f7623b61v6z 12 12 , , PUNCT f7623b61v6z 12 13 which which PRON f7623b61v6z 12 14 is be AUX f7623b61v6z 12 15 transcriptionally transcriptionally ADV f7623b61v6z 12 16 controlled control VERB f7623b61v6z 12 17 by by ADP f7623b61v6z 12 18 covrs covrs PROPN f7623b61v6z 12 19 . . PUNCT f7623b61v6z 13 1 further far ADV f7623b61v6z 13 2 , , PUNCT f7623b61v6z 13 3 the the DET f7623b61v6z 13 4 data datum NOUN f7623b61v6z 13 5 show show VERB f7623b61v6z 13 6 that that SCONJ f7623b61v6z 13 7 both both DET f7623b61v6z 13 8 fi fi NOUN f7623b61v6z 13 9 - - PUNCT f7623b61v6z 13 10 fh fh PROPN f7623b61v6z 13 11 and and CCONJ f7623b61v6z 13 12 hpm hpm NOUN f7623b61v6z 13 13 sequentially sequentially ADV f7623b61v6z 13 14 cleave cleave VERB f7623b61v6z 13 15 c3b c3b NOUN f7623b61v6z 13 16 . . PUNCT f7623b61v6z 14 1 whereas whereas SCONJ f7623b61v6z 14 2 fi fi NOUN f7623b61v6z 14 3 - - PUNCT f7623b61v6z 14 4 fh fh PROPN f7623b61v6z 14 5 proteolytically proteolytically ADV f7623b61v6z 14 6 cleaves cleave VERB f7623b61v6z 14 7 c3b c3b NOUN f7623b61v6z 14 8 into into ADP f7623b61v6z 14 9 ic3b ic3b PROPN f7623b61v6z 14 10 , , PUNCT f7623b61v6z 14 11 hpm hpm NOUN f7623b61v6z 14 12 catalyzes catalyze NOUN f7623b61v6z 14 13 cleavage cleavage NOUN f7623b61v6z 14 14 of of ADP f7623b61v6z 14 15 ic3b ic3b PROPN f7623b61v6z 14 16 into into ADP f7623b61v6z 14 17 multiple multiple ADJ f7623b61v6z 14 18 smaller small ADJ f7623b61v6z 14 19 peptides peptide NOUN f7623b61v6z 14 20 . . PUNCT f7623b61v6z 15 1 in in ADP f7623b61v6z 15 2 addition addition NOUN f7623b61v6z 15 3 , , PUNCT f7623b61v6z 15 4 the the DET f7623b61v6z 15 5 role role NOUN f7623b61v6z 15 6 of of ADP f7623b61v6z 15 7 covrs covrs ADJ f7623b61v6z 15 8 system system NOUN f7623b61v6z 15 9 was be AUX f7623b61v6z 15 10 also also ADV f7623b61v6z 15 11 examined examine VERB f7623b61v6z 15 12 in in ADP f7623b61v6z 15 13 the the DET f7623b61v6z 15 14 regulation regulation NOUN f7623b61v6z 15 15 of of ADP f7623b61v6z 15 16 htpa htpa NOUN f7623b61v6z 15 17 in in ADP f7623b61v6z 15 18 the the DET f7623b61v6z 15 19 ap53 ap53 PROPN f7623b61v6z 15 20 strain strain NOUN f7623b61v6z 15 21 . . PUNCT f7623b61v6z 16 1 htpa htpa PROPN f7623b61v6z 16 2 is be AUX f7623b61v6z 16 3 a a DET f7623b61v6z 16 4 novel novel ADJ f7623b61v6z 16 5 histidine histidine NOUN f7623b61v6z 16 6 triad triad NOUN f7623b61v6z 16 7 proteins protein NOUN f7623b61v6z 16 8 ( ( PUNCT f7623b61v6z 16 9 htp htp PROPN f7623b61v6z 16 10 ) ) PUNCT f7623b61v6z 16 11 that that PRON f7623b61v6z 16 12 is be AUX f7623b61v6z 16 13 thought think VERB f7623b61v6z 16 14 to to PART f7623b61v6z 16 15 be be AUX f7623b61v6z 16 16 regulated regulate VERB f7623b61v6z 16 17 by by ADP f7623b61v6z 16 18 covrs covrs PROPN f7623b61v6z 16 19 in in ADP f7623b61v6z 16 20 other other ADJ f7623b61v6z 16 21 strain strain NOUN f7623b61v6z 16 22 ( ( PUNCT f7623b61v6z 16 23 m23nd m23nd PROPN f7623b61v6z 16 24 ) ) PUNCT f7623b61v6z 16 25 , , PUNCT f7623b61v6z 16 26 participate participate VERB f7623b61v6z 16 27 in in ADP f7623b61v6z 16 28 zinc zinc NOUN f7623b61v6z 16 29 binding binding NOUN f7623b61v6z 16 30 , , PUNCT f7623b61v6z 16 31 and and CCONJ f7623b61v6z 16 32 considered consider VERB f7623b61v6z 16 33 as as ADP f7623b61v6z 16 34 an an DET f7623b61v6z 16 35 effective effective ADJ f7623b61v6z 16 36 vaccine vaccine NOUN f7623b61v6z 16 37 candidate candidate NOUN f7623b61v6z 16 38 against against ADP f7623b61v6z 16 39 gas gas NOUN f7623b61v6z 16 40 infections infection NOUN f7623b61v6z 16 41 . . PUNCT f7623b61v6z 17 1 interestingly interestingly ADV f7623b61v6z 17 2 , , PUNCT f7623b61v6z 17 3 our our PRON f7623b61v6z 17 4 data datum NOUN f7623b61v6z 17 5 demonstrate demonstrate VERB f7623b61v6z 17 6 that that SCONJ f7623b61v6z 17 7 while while SCONJ f7623b61v6z 17 8 htpa htpa NOUN f7623b61v6z 17 9 has have VERB f7623b61v6z 17 10 a a DET f7623b61v6z 17 11 role role NOUN f7623b61v6z 17 12 in in ADP f7623b61v6z 17 13 avoiding avoid VERB f7623b61v6z 17 14 the the DET f7623b61v6z 17 15 host host NOUN f7623b61v6z 17 16 innate innate ADJ f7623b61v6z 17 17 immunity immunity NOUN f7623b61v6z 17 18 , , PUNCT f7623b61v6z 17 19 it it PRON f7623b61v6z 17 20 is be AUX f7623b61v6z 17 21 not not PART f7623b61v6z 17 22 regulated regulate VERB f7623b61v6z 17 23 by by ADP f7623b61v6z 17 24 covrs covrs PROPN f7623b61v6z 17 25 in in ADP f7623b61v6z 17 26 the the DET f7623b61v6z 17 27 ap53 ap53 PROPN f7623b61v6z 17 28 strain strain NOUN f7623b61v6z 17 29 . . PUNCT f7623b61v6z 18 1 taken take VERB f7623b61v6z 18 2 together together ADV f7623b61v6z 18 3 , , PUNCT f7623b61v6z 18 4 these these DET f7623b61v6z 18 5 results result NOUN f7623b61v6z 18 6 indicate indicate VERB f7623b61v6z 18 7 that that SCONJ f7623b61v6z 18 8 covrs covrs PROPN f7623b61v6z 18 9 is be AUX f7623b61v6z 18 10 a a DET f7623b61v6z 18 11 critical critical ADJ f7623b61v6z 18 12 transcriptional transcriptional NOUN f7623b61v6z 18 13 regulator regulator NOUN f7623b61v6z 18 14 of of ADP f7623b61v6z 18 15 genes gene NOUN f7623b61v6z 18 16 directing direct VERB f7623b61v6z 18 17 gas gas NOUN f7623b61v6z 18 18 killing killing NOUN f7623b61v6z 18 19 by by ADP f7623b61v6z 18 20 neutrophils neutrophil NOUN f7623b61v6z 18 21 and and CCONJ f7623b61v6z 18 22 thus thus ADV f7623b61v6z 18 23 protection protection NOUN f7623b61v6z 18 24 of of ADP f7623b61v6z 18 25 bacterial bacterial ADJ f7623b61v6z 18 26 cells cell NOUN f7623b61v6z 18 27 from from ADP f7623b61v6z 18 28 the the DET f7623b61v6z 18 29 host host NOUN f7623b61v6z 18 30 complement complement NOUN f7623b61v6z 18 31 response response NOUN f7623b61v6z 18 32 . . PUNCT